chr6 : 154,645,535 – 154,646,800
1,265 bp 96 TFs 3 linked genes
This 1.3 kb open chromatin element is linked to SCAF8, CNKSR3, and TIAM2 and is bound by 96 transcription factors.
Linked Genes
3 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
SCAF8 87.1 kb Distal Multiome
CNKSR3 135.7 kb Distal Multiome
TIAM2 349.0 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr6:154,640,535 – 154,651,800
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
96 transcription factors
Source
Cell type
ATF2 2 datasets
Motif DE_36h DE_36h-ATF2_MA1632.2 10 bp overlap
Motif DE_48h DE_48h-ATF2_MA1632.2 10 bp overlap
Ahr::Arnt 3 datasets
Motif DE_36h DE_36h-AhrArnt_MA0006.2 5 bp overlap
Motif DE_48h DE_48h-AhrArnt_MA0006.2 5 bp overlap
Motif DE_60h DE_60h-AhrArnt_MA0006.2 5 bp overlap
BORCS8-MEF2B,MEF2B 1 dataset
ChIP GM12878 ENCFF427QAI 581 bp overlap
CREB1 2 datasets
Motif DE_36h DE_36h-CREB1_MA0018.5 8 bp overlap
Motif DE_48h DE_48h-CREB1_MA0018.5 8 bp overlap
CTCFL 3 datasets
Motif DE_36h DE_36h-CTCFL_MA1102.3 8 bp overlap
Motif DE_48h DE_48h-CTCFL_MA1102.3 8 bp overlap
Motif DE_60h DE_60h-CTCFL_MA1102.3 8 bp overlap
Cebpa 1 dataset
ChIP BLaER1 ENCFF262VBH 251 bp overlap
EBF1 6 datasets
ChIP GM12878 ENCFF167CZS 321 bp overlap
ChIP GM12878 ENCFF813OXE 265 bp overlap
ChIP GM12878 ENCSR000DZQ.EBF1.GM12878 137 bp overlap
ChIP GM12878 ENCSR000DZQ.EBF1.GM12878 254 bp overlap
ChIP MUTUL GSE75503.EBF1.MUTUL 616 bp overlap
ChIP NALM-6 GSE126300.EBF1.NALM-6 563 bp overlap
EOMES 2 datasets
ChIP hESC GSE26097.EOMES.hESC 269 bp overlap
ChIP hESC GSE26097.EOMES.hESC 248 bp overlap
ESR1 10 datasets
ChIP MCF-7 GSE76893.ESR1.MCF-7 161 bp overlap
ChIP MCF-7_DMSO GSE125594.ESR1.MCF-7_DMSO 235 bp overlap
ChIP MCF-7_E2_45m GSE67295.ESR1.MCF-7_E2_45m 197 bp overlap
ChIP MCF-7_ICI GSE125594.ESR1.MCF-7_ICI 236 bp overlap
ChIP MCF-7_LY2_ETOH GSE54592.ESR1.MCF-7_LY2_ETOH 148 bp overlap
ChIP MCF-7_estradiol-Dex_75min GSE99626.ESR1.MCF-7_estradiol-Dex_75min 117 bp overlap
ChIP MCF-7_parental GSE123284.ESR1.MCF-7_parental 167 bp overlap
ChIP MCF-7_parental_4-hydroxytamoxifen GSE123284.ESR1.MCF-7_parental_4-hydroxytamoxifen 181 bp overlap
ChIP MCF-7_shTEAD4 GSE125594.ESR1.MCF-7_shTEAD4 176 bp overlap
ChIP MDA-MB-134-VI_E2 GSE109103.ESR1.MDA-MB-134-VI_E2 212 bp overlap
ESR2 1 dataset
Motif DE_60h DE_60h-ESR2_MA0258.2 15 bp overlap
EWSR1-FLI1 2 datasets
Motif DE_36h DE_36h-EWSR1-FLI1_MA0149.1 18 bp overlap
Motif DE_48h DE_48h-EWSR1-FLI1_MA0149.1 18 bp overlap
FEZF1 1 dataset
ChIP HEK293 GSE76494.FEZF1.HEK293 184 bp overlap
FEZF2 1 dataset
Motif DE_36h DE_36h-FEZF2_MA2341.1 8 bp overlap
FIGLA 2 datasets
Motif DE_36h DE_36h-FIGLA_MA0820.2 6 bp overlap
Motif DE_48h DE_48h-FIGLA_MA0820.2 6 bp overlap
FOXA1 1 dataset
ChIP LNCaP_M253K GSE133386.FOXA1.LNCaP_M253K 142 bp overlap
FOXA2 4 datasets
ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.FOXA2.BJ1-hTERT_FOXA2_GATA4_Coexp 261 bp overlap
ChIP DE DE-FOXA2-1 149 bp overlap
ChIP DE DE-FOXA2-1 299 bp overlap
ChIP DE DE-FOXA2-2 409 bp overlap
FOXO1-PAX3 1 dataset
ChIP RH4_Entinostat-6H GSE116344.FOXO1-PAX3.RH4_Entinostat-6H 192 bp overlap
GATA1 2 datasets
ChIP CD34_ERYTH_BIO GSE29194.GATA1.CD34_ERYTH_BIO 124 bp overlap
ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 198 bp overlap
GATA1::TAL1 3 datasets
Motif DE_36h DE_36h-GATA1TAL1_MA0140.3 17 bp overlap
Motif DE_48h DE_48h-GATA1TAL1_MA0140.3 17 bp overlap
Motif DE_60h DE_60h-GATA1TAL1_MA0140.3 17 bp overlap
GATA2 4 datasets
ChIP CD34_ACY957 GSE60792.GATA2.CD34_ACY957 141 bp overlap
Motif DE_60h DE_60h-GATA2_MA0036.4 7 bp overlap
Motif DE_60h DE_60h-GATA2_MA0036.4 7 bp overlap
ChIP hiPSC_SLC6ebs GSE107639.GATA2.hiPSC_SLC6ebs 182 bp overlap
GATA3 2 datasets
ChIP MCF-7 GSE122847.GATA3.MCF-7 203 bp overlap
ChIP MCF-7 GSE133072.GATA3.MCF-7 261 bp overlap
GATA4 8 datasets
ChIP DE DE-GATA4-1 1028 bp overlap
ChIP DE DE-GATA4-2 1265 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
ChIP Hep-G2 GSE135714.GATA4.Hep-G2 225 bp overlap
ChIP YCC-3 GSE51705.GATA4.YCC-3 283 bp overlap
ChIP foregut GSE117136.GATA4.foregut 524 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 296 bp overlap
GATA5 1 dataset
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
GATA6 15 datasets
ChIP Caco-2_PROLIF GSE23436.GATA6.Caco-2_PROLIF 202 bp overlap
ChIP DE DE-GATA6-1 1109 bp overlap
ChIP DE DE-GATA6-2 1096 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 474 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 179 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 1265 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 1265 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 1265 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 870 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 194 bp overlap
ChIP YCC-3 GSE51705.GATA6.YCC-3 426 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 515 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 295 bp overlap
Gata3 2 datasets
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
HDAC3 1 dataset
ChIP RH4_DMSO-6H GSE116344.HDAC3.RH4_DMSO-6H 289 bp overlap
HIC2 1 dataset
Motif DE_48h DE_48h-HIC2_MA0738.2 6 bp overlap
HOXB13 1 dataset
ChIP prostate-cancer_PDX_167 GSE130408.HOXB13.prostate-cancer_PDX_167 57 bp overlap
IKZF1 1 dataset
ChIP pre-B-cell GSE107886.IKZF1.pre-B-cell 594 bp overlap
IKZF2 1 dataset
ChIP GM12878 ENCSR680UQE.IKZF2.GM12878 520 bp overlap
IKZF3 1 dataset
ChIP pre-B-cell GSE107886.IKZF3.pre-B-cell 525 bp overlap
JUN 1 dataset
ChIP DE_D2 S02-DE-d2-JUN-exp1 446 bp overlap
KLF4 1 dataset
ChIP WIBR3 GSE130417.KLF4.WIBR3 80 bp overlap
LMO2 1 dataset
ChIP Kasumi-1_SICTR GSE60130.LMO2.Kasumi-1_SICTR 146 bp overlap
MAF1 1 dataset
ChIP THP-1_macrophage_PMA GSE96800.MAF1.THP-1_macrophage_PMA 118 bp overlap
MAZ 3 datasets
Motif DE_36h DE_36h-MAZ_MA1522.2 8 bp overlap
Motif DE_48h DE_48h-MAZ_MA1522.2 8 bp overlap
Motif DE_60h DE_60h-MAZ_MA1522.2 8 bp overlap
MEF2B 1 dataset
ChIP GM12878 ENCSR177VFS.MEF2B.GM12878 620 bp overlap
MEIS1 3 datasets
ChIP CHRF28811 ERR063469.MEIS1.CHRF28811 199 bp overlap
Motif DE_36h DE_36h-MEIS1_MA0498.3 5 bp overlap
Motif DE_48h DE_48h-MEIS1_MA0498.3 5 bp overlap
MTA2 1 dataset
ChIP pre-B-cell GSE107886.MTA2.pre-B-cell 390 bp overlap
Mecom 1 dataset
Motif DE_60h DE_60h-Mecom_MA0029.2 11 bp overlap
NFKB1 3 datasets
Motif DE_36h DE_36h-NFKB1_MA0105.4 13 bp overlap
Motif DE_48h DE_48h-NFKB1_MA0105.4 13 bp overlap
Motif DE_60h DE_60h-NFKB1_MA0105.4 13 bp overlap
NKX2-2 3 datasets
Motif DE_36h DE_36h-NKX2-2_MA1645.2 8 bp overlap
Motif DE_48h DE_48h-NKX2-2_MA1645.2 8 bp overlap
Motif DE_60h DE_60h-NKX2-2_MA1645.2 8 bp overlap
NKX2-5 3 datasets
Motif DE_36h DE_36h-NKX2-5_MA0063.3 7 bp overlap
Motif DE_48h DE_48h-NKX2-5_MA0063.3 7 bp overlap
Motif DE_60h DE_60h-NKX2-5_MA0063.3 7 bp overlap
NR2C1 2 datasets
Motif DE_36h DE_36h-NR2C1_MA1535.2 6 bp overlap
Motif DE_48h DE_48h-NR2C1_MA1535.2 6 bp overlap
NR2C2 2 datasets
Motif DE_36h DE_36h-NR2C2_MA1536.2 6 bp overlap
Motif DE_48h DE_48h-NR2C2_MA1536.2 6 bp overlap
Npas4 2 datasets
Motif DE_36h DE_36h-Npas4_MA1995.2 7 bp overlap
Motif DE_48h DE_48h-Npas4_MA1995.2 7 bp overlap
Nr1H2 2 datasets
Motif DE_36h DE_36h-Nr1H2_MA1996.2 6 bp overlap
Motif DE_48h DE_48h-Nr1H2_MA1996.2 6 bp overlap
Nr1H4 2 datasets
Motif DE_36h DE_36h-Nr1H4_MA1110.3 6 bp overlap
Motif DE_48h DE_48h-Nr1H4_MA1110.3 6 bp overlap
Nr1h3 2 datasets
Motif DE_36h DE_36h-Nr1h3_MA2337.1 6 bp overlap
Motif DE_48h DE_48h-Nr1h3_MA2337.1 6 bp overlap
Nr1h3::Rxra 2 datasets
Motif DE_36h DE_36h-Nr1h3Rxra_MA0494.2 16 bp overlap
Motif DE_48h DE_48h-Nr1h3Rxra_MA0494.2 16 bp overlap
Nr2F6 1 dataset
Motif DE_36h DE_36h-Nr2F6_MA0728.1 15 bp overlap
Nr2e1 3 datasets
Motif DE_36h DE_36h-Nr2e1_MA0676.1 9 bp overlap
Motif DE_60h DE_60h-Nr2e1_MA0676.1 9 bp overlap
Motif DE_60h DE_60h-Nr2e1_MA0676.1 9 bp overlap
OSR1 3 datasets
Motif DE_36h DE_36h-OSR1_MA1542.2 8 bp overlap
Motif DE_48h DE_48h-OSR1_MA1542.2 8 bp overlap
Motif DE_60h DE_60h-OSR1_MA1542.2 8 bp overlap
OSR2 3 datasets
Motif DE_36h DE_36h-OSR2_MA1646.2 8 bp overlap
Motif DE_48h DE_48h-OSR2_MA1646.2 8 bp overlap
Motif DE_60h DE_60h-OSR2_MA1646.2 8 bp overlap
PBX3 3 datasets
Motif DE_36h DE_36h-PBX3_MA1114.2 11 bp overlap
Motif DE_48h DE_48h-PBX3_MA1114.2 11 bp overlap
Motif DE_60h DE_60h-PBX3_MA1114.2 11 bp overlap
PKNOX1 5 datasets
Motif DE_36h DE_36h-PKNOX1_MA0782.3 10 bp overlap
Motif DE_48h DE_48h-PKNOX1_MA0782.3 10 bp overlap
Motif DE_60h DE_60h-PKNOX1_MA0782.3 10 bp overlap
ChIP HEK293T ENCFF174WDB 391 bp overlap
ChIP HEK293T ENCSR233FAG.PKNOX1.HEK293T 268 bp overlap
POU5F1 1 dataset
ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 143 bp overlap
PPARA::RXRA 3 datasets
Motif DE_36h DE_36h-PPARARXRA_MA1148.2 17 bp overlap
Motif DE_48h DE_48h-PPARARXRA_MA1148.2 17 bp overlap
Motif DE_60h DE_60h-PPARARXRA_MA1148.2 17 bp overlap
PRDM6 2 datasets
ChIP HEK293 ENCFF283AJL 145 bp overlap
ChIP HEK293 ENCSR892QHR.PRDM6.HEK293 269 bp overlap
PRDM9 3 datasets
Motif DE_36h DE_36h-PRDM9_MA1723.2 20 bp overlap
Motif DE_48h DE_48h-PRDM9_MA1723.2 20 bp overlap
Motif DE_60h DE_60h-PRDM9_MA1723.2 20 bp overlap
Pparg::Rxra 3 datasets
Motif DE_36h DE_36h-PpargRxra_MA0065.3 13 bp overlap
Motif DE_48h DE_48h-PpargRxra_MA0065.3 13 bp overlap
Motif DE_60h DE_60h-PpargRxra_MA0065.3 13 bp overlap
RBM39 1 dataset
ChIP K-562 ENCSR764OXF.RBM39.K-562 159 bp overlap
RELA 1 dataset
ChIP MCF-7_Veh GSE67295.RELA.MCF-7_Veh 241 bp overlap
Rarg 2 datasets
Motif DE_36h DE_36h-Rarg_MA0860.1 17 bp overlap
Motif DE_48h DE_48h-Rarg_MA0860.1 17 bp overlap
SMAD2 1 dataset
Motif DE_60h DE_60h-SMAD2_MA1964.2 6 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 335 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 924 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 161 bp overlap
SMAD2_3 4 datasets
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 204 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 452 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 588 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 438 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 796 bp overlap
SP1 1 dataset
ChIP HEK293 GSE76494.SP1.HEK293 82 bp overlap
SP5 3 datasets
Motif DE_36h DE_36h-SP5_MA1965.2 6 bp overlap
Motif DE_48h DE_48h-SP5_MA1965.2 6 bp overlap
Motif DE_60h DE_60h-SP5_MA1965.2 6 bp overlap
SPI1 2 datasets
ChIP K-562 ENCSR000BGW.SPI1.K-562 86 bp overlap
ChIP K-562_NABUT GSE74999.SPI1.K-562_NABUT 137 bp overlap
SREBF1 2 datasets
Motif DE_36h DE_36h-SREBF1_MA0829.3 10 bp overlap
Motif DE_48h DE_48h-SREBF1_MA0829.3 10 bp overlap
SREBF2 2 datasets
Motif DE_36h DE_36h-SREBF2_MA0828.3 10 bp overlap
Motif DE_48h DE_48h-SREBF2_MA0828.3 10 bp overlap
TBX21 3 datasets
Motif DE_36h DE_36h-TBX21_MA0690.3 10 bp overlap
Motif DE_48h DE_48h-TBX21_MA0690.3 10 bp overlap
Motif DE_60h DE_60h-TBX21_MA0690.3 10 bp overlap
TFEC 2 datasets
Motif DE_36h DE_36h-TFEC_MA0871.3 8 bp overlap
Motif DE_48h DE_48h-TFEC_MA0871.3 8 bp overlap
THRA 2 datasets
Motif DE_36h DE_36h-THRA_MA1969.2 18 bp overlap
Motif DE_48h DE_48h-THRA_MA1969.2 18 bp overlap
THRB 2 datasets
Motif DE_36h DE_36h-THRB_MA1576.2 18 bp overlap
Motif DE_48h DE_48h-THRB_MA1576.2 18 bp overlap
TRPS1 2 datasets
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
ZBTB7A 1 dataset
ChIP HUDEP-2 GSE103445.ZBTB7A.HUDEP-2 294 bp overlap
ZEB1 2 datasets
Motif DE_36h DE_36h-ZEB1_MA0103.4 6 bp overlap
Motif DE_48h DE_48h-ZEB1_MA0103.4 6 bp overlap
ZNF135 1 dataset
Motif DE_36h DE_36h-ZNF135_MA1587.1 14 bp overlap
ZNF143 1 dataset
ChIP FLP143HA_T4 GSE39263.ZNF143.FLP143HA_T4 152 bp overlap
ZNF213 1 dataset
Motif DE_36h DE_36h-ZNF213_MA2121.1 12 bp overlap
ZNF257 1 dataset
Motif DE_48h DE_48h-ZNF257_MA1710.2 10 bp overlap
ZNF281 3 datasets
Motif DE_36h DE_36h-ZNF281_MA1630.3 10 bp overlap
Motif DE_48h DE_48h-ZNF281_MA1630.3 10 bp overlap
Motif DE_60h DE_60h-ZNF281_MA1630.3 10 bp overlap
ZNF341 2 datasets
ChIP HEK293 ENCFF944VMC 521 bp overlap
ChIP HEK293 ENCSR185FOY.ZNF341.HEK293 321 bp overlap
ZNF398 1 dataset
ChIP H9 GSE133630.ZNF398.H9 101 bp overlap
ZNF530 2 datasets
Motif DE_36h DE_36h-ZNF530_MA1981.2 14 bp overlap
Motif DE_60h DE_60h-ZNF530_MA1981.2 14 bp overlap
ZNF534 1 dataset
ChIP HEK293T GSE78099.ZNF534.HEK293T 104 bp overlap
ZNF610 1 dataset
Motif DE_36h DE_36h-ZNF610_MA1713.2 10 bp overlap
ZNF677 1 dataset
Motif DE_60h DE_60h-ZNF677_MA2101.1 12 bp overlap
ZNF682 3 datasets
Motif DE_36h DE_36h-ZNF682_MA1599.2 11 bp overlap
Motif DE_48h DE_48h-ZNF682_MA1599.2 11 bp overlap
Motif DE_60h DE_60h-ZNF682_MA1599.2 11 bp overlap
ZNF684 3 datasets
Motif DE_36h DE_36h-ZNF684_MA1600.2 14 bp overlap
Motif DE_48h DE_48h-ZNF684_MA1600.2 14 bp overlap
Motif DE_60h DE_60h-ZNF684_MA1600.2 14 bp overlap
ZNF736 1 dataset
ChIP HEK293T GSE78099.ZNF736.HEK293T 104 bp overlap
ZNF8 2 datasets
Motif DE_60h DE_60h-ZNF8_MA1718.1 20 bp overlap
Motif DE_60h DE_60h-ZNF8_MA1718.1 20 bp overlap
Zfp809 3 datasets
Motif DE_36h DE_36h-Zfp809_MA2125.1 9 bp overlap
Motif DE_48h DE_48h-Zfp809_MA2125.1 9 bp overlap
Motif DE_60h DE_60h-Zfp809_MA2125.1 9 bp overlap
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