chr5 : 173,232,659 – 173,232,972
313 bp 88 TFs 1 linked gene
This 313 bp open chromatin element is linked to NKX2-5 and is bound by 88 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
NKX2-5 2.3 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr5:173,227,659 – 173,237,972
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
88 transcription factors
Source
Cell type
AGO1 1 dataset
ChIP Hep-G2 ENCSR555ZMV.AGO1.Hep-G2 113 bp overlap
AR 3 datasets
ChIP MDA-MB-453 ERP003503.AR.MDA-MB-453 150 bp overlap
ChIP myofibroblast GSE90772.AR.myofibroblast 313 bp overlap
ChIP prostate_fetal-fibroblast GSE90772.AR.prostate_fetal-fibroblast 198 bp overlap
ARID4B 1 dataset
ChIP PC-3 GSE116669.ARID4B.PC-3 182 bp overlap
ARNT 1 dataset
ChIP MCF-7_aza GSE85352.ARNT.MCF-7_aza 267 bp overlap
ARNTL 1 dataset
ChIP NSC_hNP1 GSE134972.ARNTL.NSC_hNP1 313 bp overlap
ASCL1 1 dataset
Motif ES_0h ES_0h-ASCL1_MA1100.3 8 bp overlap
BCOR 1 dataset
ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 313 bp overlap
BHLHE22 1 dataset
Motif ES_0h ES_0h-BHLHE22_MA1635.2 6 bp overlap
BRD1 1 dataset
ChIP HUES-64 GSE104059.BRD1.HUES-64 52 bp overlap
BRD4 4 datasets
ChIP COLO-741 GSE73319.BRD4.COLO-741 66 bp overlap
ChIP MDA-MB-157 ERP003925.BRD4.MDA-MB-157 97 bp overlap
ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 313 bp overlap
ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 313 bp overlap
Bhlha15 1 dataset
Motif ES_0h ES_0h-Bhlha15_MA1472.3 8 bp overlap
CBX4 1 dataset
ChIP hMSC GSE117084.CBX4.hMSC 313 bp overlap
CDK9 1 dataset
ChIP HCT-116 GSE72622.CDK9.HCT-116 313 bp overlap
CHD1 3 datasets
ChIP WA01 ENCSR000AQK.CHD1.WA01 240 bp overlap
ChIP hMSC-TERT GSE89179.CHD1.hMSC-TERT 313 bp overlap
ChIP hMSC-TERT_osteoblast GSE89179.CHD1.hMSC-TERT_osteoblast 313 bp overlap
CTBP2 1 dataset
ChIP WA01 ENCSR000EUO.CTBP2.WA01 282 bp overlap
CTCF 2 datasets
ChIP 786-O_NORMOXIA GSE78113.CTCF.786-O_NORMOXIA 247 bp overlap
ChIP spleen ENCFF065CBS 313 bp overlap
E2F6 2 datasets
ChIP H1 ENCFF785DWK 66 bp overlap
ChIP WA01 ENCSR000BSI.E2F6.WA01 155 bp overlap
EED 1 dataset
ChIP ProEs GSE59087.EED.ProEs 228 bp overlap
ESR1 4 datasets
ChIP Ishikawa GSE99905.ESR1.Ishikawa 246 bp overlap
ChIP MCF-7_PaPE-1 GSE93510.ESR1.MCF-7_PaPE-1 168 bp overlap
ChIP MCF-7_PaPE-1_OA GSE93510.ESR1.MCF-7_PaPE-1_OA 313 bp overlap
ChIP MCF-7_Y537S_DMSO GSE148277.ESR1.MCF-7_Y537S_DMSO 233 bp overlap
EZH2 28 datasets
ChIP GM23248 ENCFF404ZHM 292 bp overlap
ChIP GM23338 ENCFF613YON 313 bp overlap
ChIP GM23338 ENCFF886DXX 313 bp overlap
ChIP H1 ENCFF232NZA 313 bp overlap
ChIP HUVEC-C GSE109625.EZH2.HUVEC-C 313 bp overlap
ChIP Hep-G2 ENCSR000ARI.EZH2.Hep-G2 198 bp overlap
ChIP LNCaP-abl GSE39459.EZH2.LNCaP-abl 313 bp overlap
ChIP RCH-ACV GSE135024.EZH2.RCH-ACV 57 bp overlap
ChIP THP-1 GSE135024.EZH2.THP-1 313 bp overlap
ChIP astrocyte ENCFF365JTP 313 bp overlap
ChIP endothelial cell of umbilical vein ENCFF539AKL 313 bp overlap
ChIP epithelial_mammary ENCSR000ARE.EZH2.epithelial_mammary 313 bp overlap
ChIP fibroblast of dermis ENCFF029VZK 217 bp overlap
ChIP fibroblast of dermis ENCFF029VZK 83 bp overlap
ChIP fibroblast of lung ENCFF479BAW 313 bp overlap
ChIP hESC GSE113817.EZH2.hESC 313 bp overlap
ChIP hESC_KO GSE113817.EZH2.hESC_KO 313 bp overlap
ChIP hepatocyte ENCFF552DZB 313 bp overlap
ChIP hiPSC_WTa_RNase-neg GSE128135.EZH2.hiPSC_WTa_RNase-neg 313 bp overlap
ChIP keratinocyte ENCFF070STK 303 bp overlap
ChIP keratinocyte ENCFF070STK 87 bp overlap
ChIP keratinocyte ENCFF070STK 87 bp overlap
ChIP myotube ENCSR000ASZ.EZH2.myotube 313 bp overlap
ChIP neural cell ENCFF610EPB 61 bp overlap
ChIP neural progenitor cell ENCFF018MKA 313 bp overlap
ChIP neural progenitor cell ENCFF018MKA 313 bp overlap
ChIP neural progenitor cell ENCFF472NFV 313 bp overlap
ChIP peripheral-blood-mononuclear-cell_B-cell GSE115772.EZH2.peripheral-blood-mononuclear-cell_B-cell 142 bp overlap
FOXA2 1 dataset
ChIP BJ1-hTERT_FoxHnf1aCoExp GSE90454.FOXA2.BJ1-hTERT_FoxHnf1aCoExp 211 bp overlap
FOXO1 1 dataset
ChIP CD34 GSE80773.FOXO1.CD34 235 bp overlap
GABPA 1 dataset
ChIP WA01 ENCSR000BIW.GABPA.WA01 221 bp overlap
HDAC2 1 dataset
ChIP WA01 ENCSR000AVB.HDAC2.WA01 153 bp overlap
HEXIM1 1 dataset
ChIP HCT-116 GSE72622.HEXIM1.HCT-116 252 bp overlap
HIVEP1 1 dataset
ChIP Hep-G2 ENCSR697WMX.HIVEP1.Hep-G2 313 bp overlap
HNRNPC 1 dataset
ChIP Hep-G2 GSE120104.HNRNPC.Hep-G2 173 bp overlap
HOXA3 1 dataset
ChIP Hep-G2 ENCSR999JKC.HOXA3.Hep-G2 206 bp overlap
INO80 2 datasets
ChIP Hep-G2 GSE97411.INO80.Hep-G2 134 bp overlap
ChIP Huh-7 GSE97411.INO80.Huh-7 313 bp overlap
KDM4A 1 dataset
ChIP H1 ENCFF078LED 270 bp overlap
KDM5B 2 datasets
ChIP Hep-G2 ENCSR227MRE.KDM5B.Hep-G2 310 bp overlap
ChIP SUM185_SHCTCF GSE46055.KDM5B.SUM185_SHCTCF 313 bp overlap
KDM6B 1 dataset
ChIP CUTLL1 GSE56694.KDM6B.CUTLL1 252 bp overlap
KMT2A 1 dataset
ChIP THP-1 GSE83671.KMT2A.THP-1 153 bp overlap
MBD2 1 dataset
ChIP HeLa GSE41006.MBD2.HeLa 187 bp overlap
MED1 3 datasets
ChIP G296S_2 GSE85628.MED1.G296S_2 313 bp overlap
ChIP cardiomyocyte GSE85628.MED1.cardiomyocyte 313 bp overlap
ChIP cardiomyocyte_1 GSE85628.MED1.cardiomyocyte_1 313 bp overlap
MYCN 1 dataset
ChIP NB-1643 GSE138295.MYCN.NB-1643 299 bp overlap
MYF5 1 dataset
Motif ES_0h ES_0h-MYF5_MA1641.2 8 bp overlap
MYOCD 1 dataset
ChIP A-549 GSE128921.MYOCD.A-549 298 bp overlap
MYOD1 1 dataset
ChIP IMR-90_GM GSE128527.MYOD1.IMR-90_GM 313 bp overlap
MYOG 1 dataset
Motif ES_0h ES_0h-MYOG_MA0500.3 8 bp overlap
NANOG 2 datasets
ChIP HUES-8 GSE109524.NANOG.HUES-8 242 bp overlap
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 274 bp overlap
NR2F2 2 datasets
ChIP MCF-7_E2 GSE132432.NR2F2.MCF-7_E2 313 bp overlap
ChIP MCF-7_Veh GSE132432.NR2F2.MCF-7_Veh 313 bp overlap
Neurod2 1 dataset
Motif ES_0h ES_0h-Neurod2_MA1993.2 6 bp overlap
OGG1 4 datasets
ChIP HEK293 GSE89017.OGG1.HEK293 223 bp overlap
ChIP HEK293_15min GSE89017.OGG1.HEK293_15min 313 bp overlap
ChIP HEK293_30_min GSE89017.OGG1.HEK293_30_min 256 bp overlap
ChIP HEK293_60_min GSE89017.OGG1.HEK293_60_min 134 bp overlap
Olig2 1 dataset
Motif ES_0h ES_0h-Olig2_MA1997.2 6 bp overlap
PCBP1 1 dataset
ChIP Hep-G2 GSE120104.PCBP1.Hep-G2 171 bp overlap
PCGF2 2 datasets
ChIP HEK293T_PCGF2fl GSE119618.PCGF2.HEK293T_PCGF2fl 54 bp overlap
ChIP fibroblast_MET GSE55605.PCGF2.fibroblast_MET 140 bp overlap
POLR2A 3 datasets
ChIP neural cell ENCFF604SPB 51 bp overlap
ChIP spleen ENCFF446ZGT 87 bp overlap
ChIP spleen ENCFF706IUS 71 bp overlap
POU2F1 2 datasets
ChIP T-47D GSE148277.POU2F1.T-47D 222 bp overlap
ChIP T-47D_D538G GSE148277.POU2F1.T-47D_D538G 297 bp overlap
POU5F1 4 datasets
ChIP DE_D1 DED1-OCT4_Batch_II 313 bp overlap
ChIP HUES-8 GSE109524.POU5F1.HUES-8 306 bp overlap
ChIP SKM-1 GSE93706.POU5F1.SKM-1 195 bp overlap
ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 313 bp overlap
POU5F1_M 1 dataset
ChIP DE_D1 DED1-OCT4-M_Batch_II 313 bp overlap
PRDM14 1 dataset
ChIP NCCIT GSE71675.PRDM14.NCCIT 212 bp overlap
Ptf1A 1 dataset
Motif ES_0h ES_0h-Ptf1A_MA1619.2 8 bp overlap
RBBP5 1 dataset
ChIP WA01 ENCSR000AQC.RBBP5.WA01 218 bp overlap
RBFOX2 2 datasets
ChIP HepG2 ENCFF554DMZ 313 bp overlap
ChIP HepG2 ENCFF939HTZ 313 bp overlap
REST 4 datasets
ChIP H1 ENCFF429RUE 76 bp overlap
ChIP K562 ENCFF430APM 50 bp overlap
ChIP colorectal-cancer_shCDH1 GSE112555.REST.colorectal-cancer_shCDH1 308 bp overlap
ChIP colorectal-cancer_shCTRL_intact GSE112555.REST.colorectal-cancer_shCTRL_intact 223 bp overlap
RNF2 2 datasets
ChIP H1 ENCFF239FFS 313 bp overlap
ChIP HEK293T_PCGF2fl GSE119618.RNF2.HEK293T_PCGF2fl 187 bp overlap
RORC 2 datasets
ChIP HCC70 GSE126380.RORC.HCC70 313 bp overlap
ChIP HCC70_XY018 GSE126380.RORC.HCC70_XY018 313 bp overlap
RUNX1 4 datasets
ChIP AML_Blast GSE60130.RUNX1.AML_Blast 165 bp overlap
ChIP CD34 GSE64862.RUNX1.CD34 165 bp overlap
ChIP H9_DOX-5_HA GSE137670.RUNX1.H9_DOX-5_HA 306 bp overlap
ChIP Jurkat GSE85524.RUNX1.Jurkat 302 bp overlap
RUNX1T1 1 dataset
ChIP Kasumi-1_E2 GSE102697.RUNX1T1.Kasumi-1_E2 153 bp overlap
SAFB 1 dataset
ChIP K-562 ENCSR072VUO.SAFB.K-562 93 bp overlap
SIRT6 2 datasets
ChIP SK-MEL-239_L-C-B GSE102813.SIRT6.SK-MEL-239_L-C-B 156 bp overlap
ChIP SK-MEL-239_L-C-B GSE102813.SIRT6.SK-MEL-239_L-C-B 82 bp overlap
SMAD2-3 4 datasets
ChIP HUES-8 GSE109524.SMAD2-3.HUES-8 313 bp overlap
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 313 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 65 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 134 bp overlap
SMAD2_3 2 datasets
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 125 bp overlap
ChIP ESC S33-ESC-d0-SMAD2_3-exp2 313 bp overlap
SMC1 1 dataset
ChIP IMR-90_OIS GSE118494.SMC1.IMR-90_OIS 195 bp overlap
SREBP2 2 datasets
ChIP HCC70 GSE126380.SREBP2.HCC70 313 bp overlap
ChIP HCC70_XY018 GSE126380.SREBP2.HCC70_XY018 313 bp overlap
SRSF7 1 dataset
ChIP Hep-G2 GSE120104.SRSF7.Hep-G2 255 bp overlap
SSRP1 1 dataset
ChIP HT-1080_AclacinomycinA GSE107595.SSRP1.HT-1080_AclacinomycinA 313 bp overlap
STAT1 1 dataset
ChIP CD14_LPS GSE43036.STAT1.CD14_LPS 75 bp overlap
STAT3 1 dataset
ChIP WA01 ERP004237.STAT3.WA01 311 bp overlap
SUZ12 12 datasets
ChIP GM12878 ENCFF498QAM 251 bp overlap
ChIP GM12878 ENCSR744XTG.SUZ12.GM12878 313 bp overlap
ChIP H1 ENCFF507HGF 268 bp overlap
ChIP H1 ENCFF881NFR 313 bp overlap
ChIP HEK293T_PCGF135fl_OHT GSE119618.SUZ12.HEK293T_PCGF135fl_OHT 56 bp overlap
ChIP HEK293T_PCGF2fl GSE119618.SUZ12.HEK293T_PCGF2fl 232 bp overlap
ChIP LNCaP-abl GSE39459.SUZ12.LNCaP-abl 269 bp overlap
ChIP NT2-D1 GSE101538.SUZ12.NT2-D1 313 bp overlap
ChIP NT2/D1 ENCFF574SXS 306 bp overlap
ChIP NT2/D1 ENCFF574SXS 79 bp overlap
ChIP hiPSC_WTa_RNase-neg GSE128135.SUZ12.hiPSC_WTa_RNase-neg 304 bp overlap
ChIP hiPSC_WTb_RNase-neg GSE128135.SUZ12.hiPSC_WTb_RNase-neg 313 bp overlap
TCF12 1 dataset
ChIP WA01 ENCSR000BIT.TCF12.WA01 218 bp overlap
TFAP2C 1 dataset
ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 305 bp overlap
TFAP4::FLI1 1 dataset
Motif ES_0h ES_0h-TFAP4FLI1_MA1967.2 14 bp overlap
TFIIIC 1 dataset
ChIP HEK293 GSE119418.TFIIIC.HEK293 298 bp overlap
TP63 1 dataset
ChIP keratinocyte GSE33571.TP63.keratinocyte 107 bp overlap
TRIM25 1 dataset
ChIP BT-549 GSE79588.TRIM25.BT-549 313 bp overlap
Tcf12 1 dataset
Motif ES_0h ES_0h-Tcf12_MA0521.3 6 bp overlap
Tfcp2l1 1 dataset
Motif ES_0h ES_0h-Tfcp2l1_MA0145.2 14 bp overlap
Twist2 1 dataset
Motif ES_0h ES_0h-Twist2_MA0633.3 6 bp overlap
WDR5 1 dataset
ChIP SMMC-7721 GSE126982.WDR5.SMMC-7721 313 bp overlap
YY1 1 dataset
ChIP Huh-7 GSE97411.YY1.Huh-7 259 bp overlap
ZBTB33 1 dataset
ChIP K562 ENCFF427SDV 118 bp overlap
ZBTB48 1 dataset
ChIP U2OS_ZBTB48-KO GSE96776.ZBTB48.U2OS_ZBTB48-KO 313 bp overlap
ZNF736 1 dataset
ChIP HEK293T GSE78099.ZNF736.HEK293T 99 bp overlap
ZNF800 1 dataset
ChIP Hep-G2 ENCSR701WPG.ZNF800.Hep-G2 152 bp overlap
ZNF891 1 dataset
ChIP Hep-G2 ENCSR020CLV.ZNF891.Hep-G2 85 bp overlap
ZNF90 1 dataset
ChIP HEK293T GSE78099.ZNF90.HEK293T 51 bp overlap
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