chr3 : 178,964,368 – 178,964,920
552 bp 96 TFs 5 linked genes
This 552 bp open chromatin element is linked to 5 target genes and is bound by 96 transcription factors.
Linked Genes
5 genes
Link type
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
KCNMB2-AS1 104.3 kb Distal Multiome
ZMAT3 107.1 kb Distal Multiome
PIK3CA 183.6 kb Distal Multiome
KCNMB3 295.1 kb Distal Multiome
KCNMB2 428.3 kb Distal Multiome+HiCAR
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr3:178,959,368 – 178,969,920
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
96 transcription factors
Source
Cell type
ARNT2 3 datasets
Motif DE_36h DE_36h-ARNT2_MA1464.2 8 bp overlap
Motif DE_48h DE_48h-ARNT2_MA1464.2 8 bp overlap
Motif DE_60h DE_60h-ARNT2_MA1464.2 8 bp overlap
ARNT::HIF1A 4 datasets
Motif DE_36h DE_36h-ARNTHIF1A_MA0259.2 5 bp overlap
Motif DE_36h DE_36h-ARNTHIF1A_MA0259.2 5 bp overlap
Motif DE_48h DE_48h-ARNTHIF1A_MA0259.2 5 bp overlap
Motif DE_60h DE_60h-ARNTHIF1A_MA0259.2 5 bp overlap
Arnt 3 datasets
Motif DE_36h DE_36h-Arnt_MA0004.1 6 bp overlap
Motif DE_48h DE_48h-Arnt_MA0004.1 6 bp overlap
Motif DE_60h DE_60h-Arnt_MA0004.1 6 bp overlap
Arntl 3 datasets
Motif DE_36h DE_36h-Arntl_MA0603.2 8 bp overlap
Motif DE_48h DE_48h-Arntl_MA0603.2 8 bp overlap
Motif DE_60h DE_60h-Arntl_MA0603.2 8 bp overlap
BHLHE40 3 datasets
Motif DE_36h DE_36h-BHLHE40_MA0464.3 8 bp overlap
Motif DE_48h DE_48h-BHLHE40_MA0464.3 8 bp overlap
Motif DE_60h DE_60h-BHLHE40_MA0464.3 8 bp overlap
BHLHE41 3 datasets
Motif DE_36h DE_36h-BHLHE41_MA0636.1 10 bp overlap
Motif DE_48h DE_48h-BHLHE41_MA0636.1 10 bp overlap
Motif DE_60h DE_60h-BHLHE41_MA0636.1 10 bp overlap
CLOCK 3 datasets
Motif DE_36h DE_36h-CLOCK_MA0819.3 7 bp overlap
Motif DE_48h DE_48h-CLOCK_MA0819.3 7 bp overlap
Motif DE_60h DE_60h-CLOCK_MA0819.3 7 bp overlap
Crx 3 datasets
Motif DE_36h DE_36h-Crx_MA0467.3 6 bp overlap
Motif DE_48h DE_48h-Crx_MA0467.3 6 bp overlap
Motif DE_60h DE_60h-Crx_MA0467.3 6 bp overlap
Dmbx1 3 datasets
Motif DE_36h DE_36h-Dmbx1_MA0883.2 10 bp overlap
Motif DE_48h DE_48h-Dmbx1_MA0883.2 10 bp overlap
Motif DE_60h DE_60h-Dmbx1_MA0883.2 10 bp overlap
EHF 2 datasets
Motif DE_36h DE_36h-EHF_MA0598.4 9 bp overlap
Motif DE_60h DE_60h-EHF_MA0598.4 9 bp overlap
ELF1 2 datasets
Motif DE_36h DE_36h-ELF1_MA0473.4 9 bp overlap
Motif DE_60h DE_60h-ELF1_MA0473.4 9 bp overlap
ELF2 3 datasets
Motif DE_36h DE_36h-ELF2_MA1483.3 10 bp overlap
Motif DE_48h DE_48h-ELF2_MA1483.3 10 bp overlap
Motif DE_60h DE_60h-ELF2_MA1483.3 10 bp overlap
ELF3 2 datasets
Motif DE_36h DE_36h-ELF3_MA0640.3 9 bp overlap
Motif DE_60h DE_60h-ELF3_MA0640.3 9 bp overlap
ELK4 2 datasets
Motif DE_36h DE_36h-ELK4_MA0076.3 9 bp overlap
Motif DE_60h DE_60h-ELK4_MA0076.3 9 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 416 bp overlap
ETS1 1 dataset
ChIP cardiomyocyte_D2 GSE129986.ETS1.cardiomyocyte_D2 278 bp overlap
ETV1 3 datasets
Motif DE_36h DE_36h-ETV1_MA0761.3 9 bp overlap
Motif DE_48h DE_48h-ETV1_MA0761.3 9 bp overlap
Motif DE_60h DE_60h-ETV1_MA0761.3 9 bp overlap
Erg 2 datasets
Motif DE_36h DE_36h-Erg_MA0474.4 10 bp overlap
Motif DE_60h DE_60h-Erg_MA0474.4 10 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 552 bp overlap
ChIP DE DE-FOXA2-2 474 bp overlap
FOXO6 3 datasets
Motif DE_36h DE_36h-FOXO6_MA0849.1 7 bp overlap
Motif DE_48h DE_48h-FOXO6_MA0849.1 7 bp overlap
Motif DE_60h DE_60h-FOXO6_MA0849.1 7 bp overlap
Foxj2 3 datasets
Motif DE_36h DE_36h-Foxj2_MA0614.1 8 bp overlap
Motif DE_48h DE_48h-Foxj2_MA0614.1 8 bp overlap
Motif DE_60h DE_60h-Foxj2_MA0614.1 8 bp overlap
GABPA 2 datasets
Motif DE_36h DE_36h-GABPA_MA0062.4 10 bp overlap
Motif DE_60h DE_60h-GABPA_MA0062.4 10 bp overlap
GATA1::TAL1 2 datasets
Motif DE_36h DE_36h-GATA1TAL1_MA0140.3 17 bp overlap
Motif DE_60h DE_60h-GATA1TAL1_MA0140.3 17 bp overlap
GATA2 1 dataset
ChIP TF1 GSE73207.GATA2.TF1 405 bp overlap
GATA4 5 datasets
ChIP DE DE-GATA4-1 552 bp overlap
ChIP DE DE-GATA4-2 552 bp overlap
ChIP foregut GSE117136.GATA4.foregut 515 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 516 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 300 bp overlap
GATA6 14 datasets
ChIP AGS GSE51705.GATA6.AGS 152 bp overlap
ChIP DE DE-GATA6-1 552 bp overlap
ChIP DE DE-GATA6-2 552 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 552 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 552 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 545 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 552 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 552 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 552 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 552 bp overlap
ChIP foregut GSE117136.GATA6.foregut 416 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 358 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 506 bp overlap
ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 457 bp overlap
GSC 3 datasets
Motif DE_36h DE_36h-GSC_MA0648.2 6 bp overlap
Motif DE_48h DE_48h-GSC_MA0648.2 6 bp overlap
Motif DE_60h DE_60h-GSC_MA0648.2 6 bp overlap
GSC2 3 datasets
Motif DE_36h DE_36h-GSC2_MA0891.2 6 bp overlap
Motif DE_48h DE_48h-GSC2_MA0891.2 6 bp overlap
Motif DE_60h DE_60h-GSC2_MA0891.2 6 bp overlap
HDAC3 1 dataset
ChIP RH4_DMSO-6H GSE116344.HDAC3.RH4_DMSO-6H 99 bp overlap
HIC2 1 dataset
Motif DE_36h DE_36h-HIC2_MA0738.2 6 bp overlap
HOXB4 3 datasets
Motif DE_36h DE_36h-HOXB4_MA1499.2 6 bp overlap
Motif DE_48h DE_48h-HOXB4_MA1499.2 6 bp overlap
Motif DE_60h DE_60h-HOXB4_MA1499.2 6 bp overlap
HOXC4 3 datasets
Motif DE_36h DE_36h-HOXC4_MA1504.2 6 bp overlap
Motif DE_48h DE_48h-HOXC4_MA1504.2 6 bp overlap
Motif DE_60h DE_60h-HOXC4_MA1504.2 6 bp overlap
HOXD3 3 datasets
Motif DE_36h DE_36h-HOXD3_MA0912.2 8 bp overlap
Motif DE_48h DE_48h-HOXD3_MA0912.2 8 bp overlap
Motif DE_60h DE_60h-HOXD3_MA0912.2 8 bp overlap
HOXD4 3 datasets
Motif DE_36h DE_36h-HOXD4_MA1507.2 6 bp overlap
Motif DE_48h DE_48h-HOXD4_MA1507.2 6 bp overlap
Motif DE_60h DE_60h-HOXD4_MA1507.2 6 bp overlap
Hmx2 3 datasets
Motif DE_36h DE_36h-Hmx2_MA0897.2 15 bp overlap
Motif DE_48h DE_48h-Hmx2_MA0897.2 15 bp overlap
Motif DE_60h DE_60h-Hmx2_MA0897.2 15 bp overlap
Ikzf3 2 datasets
Motif DE_36h DE_36h-Ikzf3_MA1992.2 9 bp overlap
Motif DE_60h DE_60h-Ikzf3_MA1992.2 9 bp overlap
JUN 2 datasets
ChIP DE_D2 S02-DE-d2-JUN-exp1 351 bp overlap
ChIP DE_D2 S54-DE-d2-JUN-exp2 334 bp overlap
MAX 3 datasets
Motif DE_36h DE_36h-MAX_MA0058.4 6 bp overlap
Motif DE_48h DE_48h-MAX_MA0058.4 6 bp overlap
Motif DE_60h DE_60h-MAX_MA0058.4 6 bp overlap
MEIS1 1 dataset
Motif DE_36h DE_36h-MEIS1_MA0498.3 5 bp overlap
MLXIPL 3 datasets
Motif DE_36h DE_36h-MLXIPL_MA0664.2 8 bp overlap
Motif DE_48h DE_48h-MLXIPL_MA0664.2 8 bp overlap
Motif DE_60h DE_60h-MLXIPL_MA0664.2 8 bp overlap
MNT 3 datasets
Motif DE_36h DE_36h-MNT_MA0825.2 6 bp overlap
Motif DE_48h DE_48h-MNT_MA0825.2 6 bp overlap
Motif DE_60h DE_60h-MNT_MA0825.2 6 bp overlap
MYB 2 datasets
Motif DE_36h DE_36h-MYB_MA0100.4 6 bp overlap
ChIP Loucy GSE94000.MYB.Loucy 223 bp overlap
Mlxip 3 datasets
Motif DE_36h DE_36h-Mlxip_MA0622.2 6 bp overlap
Motif DE_48h DE_48h-Mlxip_MA0622.2 6 bp overlap
Motif DE_60h DE_60h-Mlxip_MA0622.2 6 bp overlap
NFKB1 1 dataset
Motif DE_36h DE_36h-NFKB1_MA0105.4 13 bp overlap
NKX2-2 2 datasets
Motif DE_36h DE_36h-NKX2-2_MA1645.2 8 bp overlap
Motif DE_60h DE_60h-NKX2-2_MA1645.2 8 bp overlap
NR2F6 1 dataset
ChIP K-562 ENCSR707QWA.NR2F6.K-562 192 bp overlap
Nr1h3::Rxra 3 datasets
Motif DE_36h DE_36h-Nr1h3Rxra_MA0494.2 16 bp overlap
Motif DE_48h DE_48h-Nr1h3Rxra_MA0494.2 16 bp overlap
Motif DE_60h DE_60h-Nr1h3Rxra_MA0494.2 16 bp overlap
Nr2F6 2 datasets
Motif DE_36h DE_36h-Nr2F6_MA0728.1 15 bp overlap
Motif DE_60h DE_60h-Nr2F6_MA0728.1 15 bp overlap
Nr2e3 1 dataset
Motif DE_36h DE_36h-Nr2e3_MA0164.2 6 bp overlap
OTX1 3 datasets
Motif DE_36h DE_36h-OTX1_MA0711.2 6 bp overlap
Motif DE_48h DE_48h-OTX1_MA0711.2 6 bp overlap
Motif DE_60h DE_60h-OTX1_MA0711.2 6 bp overlap
OTX2 3 datasets
Motif DE_36h DE_36h-OTX2_MA0712.3 7 bp overlap
Motif DE_48h DE_48h-OTX2_MA0712.3 7 bp overlap
Motif DE_60h DE_60h-OTX2_MA0712.3 7 bp overlap
PAX3 3 datasets
Motif DE_36h DE_36h-PAX3_MA1546.2 14 bp overlap
Motif DE_48h DE_48h-PAX3_MA1546.2 14 bp overlap
Motif DE_60h DE_60h-PAX3_MA1546.2 14 bp overlap
PDX1 1 dataset
ChIP pancreatic-progenitor GSE117136.PDX1.pancreatic-progenitor 385 bp overlap
PITX1 3 datasets
Motif DE_36h DE_36h-PITX1_MA0682.3 6 bp overlap
Motif DE_48h DE_48h-PITX1_MA0682.3 6 bp overlap
Motif DE_60h DE_60h-PITX1_MA0682.3 6 bp overlap
PITX2 3 datasets
Motif DE_36h DE_36h-PITX2_MA1547.2 8 bp overlap
Motif DE_48h DE_48h-PITX2_MA1547.2 8 bp overlap
Motif DE_60h DE_60h-PITX2_MA1547.2 8 bp overlap
PITX3 3 datasets
Motif DE_36h DE_36h-PITX3_MA0714.2 6 bp overlap
Motif DE_48h DE_48h-PITX3_MA0714.2 6 bp overlap
Motif DE_60h DE_60h-PITX3_MA0714.2 6 bp overlap
POU1F1 3 datasets
Motif DE_36h DE_36h-POU1F1_MA0784.3 14 bp overlap
Motif DE_48h DE_48h-POU1F1_MA0784.3 14 bp overlap
Motif DE_60h DE_60h-POU1F1_MA0784.3 14 bp overlap
POU2F1 3 datasets
Motif DE_36h DE_36h-POU2F1_MA0785.2 9 bp overlap
Motif DE_48h DE_48h-POU2F1_MA0785.2 9 bp overlap
Motif DE_60h DE_60h-POU2F1_MA0785.2 9 bp overlap
POU2F2 3 datasets
Motif DE_36h DE_36h-POU2F2_MA0507.3 13 bp overlap
Motif DE_48h DE_48h-POU2F2_MA0507.3 13 bp overlap
Motif DE_60h DE_60h-POU2F2_MA0507.3 13 bp overlap
POU3F1 3 datasets
Motif DE_36h DE_36h-POU3F1_MA0786.2 10 bp overlap
Motif DE_48h DE_48h-POU3F1_MA0786.2 10 bp overlap
Motif DE_60h DE_60h-POU3F1_MA0786.2 10 bp overlap
POU3F2 3 datasets
Motif DE_36h DE_36h-POU3F2_MA0787.1 12 bp overlap
Motif DE_48h DE_48h-POU3F2_MA0787.1 12 bp overlap
Motif DE_60h DE_60h-POU3F2_MA0787.1 12 bp overlap
POU3F3 3 datasets
Motif DE_36h DE_36h-POU3F3_MA0788.1 13 bp overlap
Motif DE_48h DE_48h-POU3F3_MA0788.1 13 bp overlap
Motif DE_60h DE_60h-POU3F3_MA0788.1 13 bp overlap
POU3F4 3 datasets
Motif DE_36h DE_36h-POU3F4_MA0789.1 9 bp overlap
Motif DE_48h DE_48h-POU3F4_MA0789.1 9 bp overlap
Motif DE_60h DE_60h-POU3F4_MA0789.1 9 bp overlap
POU5F1B 3 datasets
Motif DE_36h DE_36h-POU5F1B_MA0792.1 9 bp overlap
Motif DE_48h DE_48h-POU5F1B_MA0792.1 9 bp overlap
Motif DE_60h DE_60h-POU5F1B_MA0792.1 9 bp overlap
POU6F1 3 datasets
Motif DE_36h DE_36h-POU6F1_MA1549.2 7 bp overlap
Motif DE_48h DE_48h-POU6F1_MA1549.2 7 bp overlap
Motif DE_60h DE_60h-POU6F1_MA1549.2 7 bp overlap
POU6F2 3 datasets
Motif DE_36h DE_36h-POU6F2_MA0793.2 9 bp overlap
Motif DE_48h DE_48h-POU6F2_MA0793.2 9 bp overlap
Motif DE_60h DE_60h-POU6F2_MA0793.2 9 bp overlap
Plagl1 2 datasets
Motif DE_36h DE_36h-Plagl1_MA1615.2 8 bp overlap
Motif DE_48h DE_48h-Plagl1_MA1615.2 8 bp overlap
RHOXF1 3 datasets
Motif DE_36h DE_36h-RHOXF1_MA0719.2 6 bp overlap
Motif DE_48h DE_48h-RHOXF1_MA0719.2 6 bp overlap
Motif DE_60h DE_60h-RHOXF1_MA0719.2 6 bp overlap
RUNX3 3 datasets
Motif DE_36h DE_36h-RUNX3_MA0684.3 8 bp overlap
Motif DE_48h DE_48h-RUNX3_MA0684.3 8 bp overlap
Motif DE_60h DE_60h-RUNX3_MA0684.3 8 bp overlap
Rarg 3 datasets
Motif DE_36h DE_36h-Rarg_MA0860.1 17 bp overlap
Motif DE_48h DE_48h-Rarg_MA0860.1 17 bp overlap
Motif DE_60h DE_60h-Rarg_MA0860.1 17 bp overlap
SMAD2-3 2 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 486 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 438 bp overlap
SMAD2_3 2 datasets
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 459 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 451 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 339 bp overlap
SP5 1 dataset
Motif DE_36h DE_36h-SP5_MA1965.2 6 bp overlap
SREBF1 3 datasets
Motif DE_36h DE_36h-SREBF1_MA0595.1 10 bp overlap
Motif DE_48h DE_48h-SREBF1_MA0595.1 10 bp overlap
Motif DE_60h DE_60h-SREBF1_MA0595.1 10 bp overlap
SREBF2 3 datasets
Motif DE_36h DE_36h-SREBF2_MA0596.1 10 bp overlap
Motif DE_48h DE_48h-SREBF2_MA0596.1 10 bp overlap
Motif DE_60h DE_60h-SREBF2_MA0596.1 10 bp overlap
STAT1 3 datasets
Motif DE_36h DE_36h-STAT1_MA0137.4 9 bp overlap
Motif DE_48h DE_48h-STAT1_MA0137.4 9 bp overlap
Motif DE_60h DE_60h-STAT1_MA0137.4 9 bp overlap
Stat5a 3 datasets
Motif DE_36h DE_36h-Stat5a_MA1624.2 9 bp overlap
Motif DE_48h DE_48h-Stat5a_MA1624.2 9 bp overlap
Motif DE_60h DE_60h-Stat5a_MA1624.2 9 bp overlap
Stat5a::Stat5b 3 datasets
Motif DE_36h DE_36h-Stat5aStat5b_MA0519.2 9 bp overlap
Motif DE_48h DE_48h-Stat5aStat5b_MA0519.2 9 bp overlap
Motif DE_60h DE_60h-Stat5aStat5b_MA0519.2 9 bp overlap
Stat5b 3 datasets
Motif DE_36h DE_36h-Stat5b_MA1625.2 9 bp overlap
Motif DE_48h DE_48h-Stat5b_MA1625.2 9 bp overlap
Motif DE_60h DE_60h-Stat5b_MA1625.2 9 bp overlap
T 1 dataset
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 340 bp overlap
TAL1 2 datasets
ChIP PRIMA2 GSE33850.TAL1.PRIMA2 168 bp overlap
ChIP ProEs GSE59087.TAL1.ProEs 117 bp overlap
TCF7L2 1 dataset
ChIP MDA-MB-453 GSE45201.TCF7L2.MDA-MB-453 66 bp overlap
THRA 3 datasets
Motif DE_36h DE_36h-THRA_MA1969.2 18 bp overlap
Motif DE_48h DE_48h-THRA_MA1969.2 18 bp overlap
Motif DE_60h DE_60h-THRA_MA1969.2 18 bp overlap
THRB 3 datasets
Motif DE_36h DE_36h-THRB_MA1576.2 18 bp overlap
Motif DE_48h DE_48h-THRB_MA1576.2 18 bp overlap
Motif DE_60h DE_60h-THRB_MA1576.2 18 bp overlap
TP53 1 dataset
Motif DE_36h DE_36h-TP53_MA0106.3 18 bp overlap
TP63 1 dataset
Motif DE_36h DE_36h-TP63_MA0525.2 18 bp overlap
TP73 1 dataset
Motif DE_36h DE_36h-TP73_MA0861.2 16 bp overlap
Thap11 2 datasets
Motif DE_36h DE_36h-Thap11_MA1573.2 14 bp overlap
Motif DE_60h DE_60h-Thap11_MA1573.2 14 bp overlap
Vdr 3 datasets
Motif DE_36h DE_36h-Vdr_MA0693.4 7 bp overlap
Motif DE_48h DE_48h-Vdr_MA0693.4 7 bp overlap
Motif DE_60h DE_60h-Vdr_MA0693.4 7 bp overlap
ZKSCAN5 3 datasets
Motif DE_36h DE_36h-ZKSCAN5_MA1652.2 9 bp overlap
Motif DE_48h DE_48h-ZKSCAN5_MA1652.2 9 bp overlap
Motif DE_60h DE_60h-ZKSCAN5_MA1652.2 9 bp overlap
ZNF263 1 dataset
Motif DE_36h DE_36h-ZNF263_MA0528.3 7 bp overlap
ZNF281 1 dataset
Motif DE_36h DE_36h-ZNF281_MA1630.3 10 bp overlap
ZNF354A 1 dataset
Motif DE_36h DE_36h-ZNF354A_MA1978.2 20 bp overlap
ZNF460 1 dataset
Motif DE_36h DE_36h-ZNF460_MA1596.1 16 bp overlap
ZNF707 2 datasets
Motif DE_36h DE_36h-ZNF707_MA1715.1 15 bp overlap
Motif DE_60h DE_60h-ZNF707_MA1715.1 15 bp overlap
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