chr2:202,163,899–202,164,942

chr2 : 202,163,899 – 202,164,942

1,043 bp 79 TFs 7 linked genes

This 1.0 kb open chromatin element is linked to 7 target genes and is bound by 79 transcription factors.

Linked Genes

7 genes

Gene	Expression	Dist. to TSS	Distance	Link type
SUMO1		74.1 kb	Distal	Multiome
NOP58		101.2 kb	Distal	Multiome
FZD7		130.7 kb	Distal	Multiome+HiCAR
ENSG00000273209		131.0 kb	Distal	Multiome+HiCAR
ENSG00000273456		211.6 kb	Distal	Multiome
BMPR2		211.8 kb	Distal	Multiome
ALS2		383.4 kb	Distal	Multiome+HiCAR

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

79 transcription factors

BRD2 2 datasets

ChIP MV4-11_DMSO GSE120715.BRD2.MV4-11_DMSO 144 bp overlap

ChIP MV4-11_IBET151_50nM GSE120715.BRD2.MV4-11_IBET151_50nM 141 bp overlap

ChIP MV4-11_IBET151_5000nM GSE120715.BRD3.MV4-11_IBET151_5000nM 151 bp overlap

CEBPB 1 dataset

ChIP IMR-90 ENCFF468UGY 251 bp overlap

ChIP 501-mel GSE134848.CHD4.501-mel 162 bp overlap

ChIP T-47D GSE62428.CHD8.T-47D 160 bp overlap

Cebpa 3 datasets

ChIP BLaER1 ENCFF093OYK 383 bp overlap

ChIP BLaER1 ENCFF364PUR 260 bp overlap

ChIP BLaER1 ENCFF460KDD 271 bp overlap

Motif DE_72h DE_72h-Crx_MA0467.3 6 bp overlap

Dmbx1 1 dataset

Motif DE_72h DE_72h-Dmbx1_MA0883.2 10 bp overlap

ChIP K-562 ENCSR000BMD.ELF1.K-562 117 bp overlap

EOMES 2 datasets

ChIP hESC GSE26097.EOMES.hESC 208 bp overlap

ChIP hESC GSE26097.EOMES.hESC 262 bp overlap

ERF::HOXB13 2 datasets

Motif DE_60h DE_60h-ERFHOXB13_MA1937.2 13 bp overlap

Motif DE_72h DE_72h-ERFHOXB13_MA1937.2 13 bp overlap

ESR2 2 datasets

Motif DE_60h DE_60h-ESR2_MA0258.2 15 bp overlap

Motif DE_72h DE_72h-ESR2_MA0258.2 15 bp overlap

ESRRA 1 dataset

Motif DE_72h DE_72h-ESRRA_MA0592.4 9 bp overlap

ESRRB 1 dataset

Motif DE_72h DE_72h-ESRRB_MA0141.4 10 bp overlap

ChIP neural progenitor cell ENCFF018MKA 754 bp overlap

FOXA2 3 datasets

ChIP DE DE-FOXA2-1 842 bp overlap

ChIP DE DE-FOXA2-2 286 bp overlap

ChIP DE DE-FOXA2-2 534 bp overlap

GATA2 1 dataset

ChIP hiPSC_SLC9ebs GSE107639.GATA2.hiPSC_SLC9ebs 292 bp overlap

GATA3 1 dataset

ChIP SK-N-SH ENCFF040SSB 365 bp overlap

GATA4 7 datasets

ChIP DE DE-GATA4-1 945 bp overlap

ChIP DE DE-GATA4-2 964 bp overlap

Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap

Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap

ChIP foregut GSE117136.GATA4.foregut 443 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 295 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 395 bp overlap

GATA5 1 dataset

Motif DE_72h DE_72h-GATA5_MA0766.3 8 bp overlap

GATA6 11 datasets

ChIP DE DE-GATA6-1 927 bp overlap

ChIP DE DE-GATA6-2 973 bp overlap

Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 959 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 809 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 879 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 1000 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 926 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 862 bp overlap

ChIP foregut GSE117136.GATA6.foregut 830 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 390 bp overlap

Motif DE_72h DE_72h-GSC_MA0648.2 6 bp overlap

Motif DE_72h DE_72h-GSC2_MA0891.2 6 bp overlap

Gata3 1 dataset

Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap

HNF4A 3 datasets

ChIP Caco-2_DIFF GSE23436.HNF4A.Caco-2_DIFF 177 bp overlap

Motif DE_72h DE_72h-HNF4A_MA0114.5 9 bp overlap

ChIP hiPSC GSE104613.HNF4A.hiPSC 322 bp overlap

HNF4G 1 dataset

Motif DE_72h DE_72h-HNF4G_MA0484.3 9 bp overlap

Motif DE_72h DE_72h-IRF3_MA1418.2 17 bp overlap

Motif DE_72h DE_72h-IRF5_MA1420.1 14 bp overlap

LIN54 1 dataset

Motif DE_72h DE_72h-LIN54_MA0619.2 7 bp overlap

ChIP melanocyte_CTR GSE50681.MITF.melanocyte_CTR 205 bp overlap

Msgn1 1 dataset

Motif DE_72h DE_72h-Msgn1_MA1524.3 10 bp overlap

NEUROD1 2 datasets

ChIP D283-Med_shNEUROD1-1579 GSE92582.NEUROD1.D283-Med_shNEUROD1-1579 203 bp overlap

ChIP D341-Med_shNEUROD1-1579 GSE92582.NEUROD1.D341-Med_shNEUROD1-1579 191 bp overlap

NFATC3 1 dataset

Motif DE_72h DE_72h-NFATC3_MA0625.3 6 bp overlap

NR3C1 1 dataset

ChIP A-549 ENCSR000BHF.NR3C1.A-549 206 bp overlap

NR5A1 1 dataset

Motif DE_72h DE_72h-NR5A1_MA1540.3 12 bp overlap

Nfat5 1 dataset

Motif DE_72h DE_72h-Nfat5_MA0606.3 8 bp overlap

Nfatc1 1 dataset

Motif DE_72h DE_72h-Nfatc1_MA0624.3 6 bp overlap

Nfatc2 1 dataset

Motif DE_72h DE_72h-Nfatc2_MA0152.3 8 bp overlap

Nr5A2 1 dataset

Motif DE_72h DE_72h-Nr5A2_MA0505.3 9 bp overlap

Motif DE_72h DE_72h-OTX1_MA0711.2 6 bp overlap

PITX1 1 dataset

Motif DE_72h DE_72h-PITX1_MA0682.3 6 bp overlap

PITX3 1 dataset

Motif DE_72h DE_72h-PITX3_MA0714.2 6 bp overlap

PPARD 1 dataset

Motif DE_72h DE_72h-PPARD_MA1550.2 14 bp overlap

PRDM9 1 dataset

Motif DE_72h DE_72h-PRDM9_MA1723.2 20 bp overlap

RHOXF1 1 dataset

Motif DE_72h DE_72h-RHOXF1_MA0719.2 6 bp overlap

Motif DE_72h DE_72h-RXRB_MA0855.1 14 bp overlap

Motif DE_72h DE_72h-RXRG_MA0856.1 14 bp overlap

Motif DE_72h DE_72h-Rarb_MA0857.1 16 bp overlap

Motif DE_72h DE_72h-Rarg_MA0859.2 15 bp overlap

Motif DE_72h DE_72h-Rxra_MA0512.2 14 bp overlap

SIN3A 1 dataset

ChIP HUVEC-C GSE103245.SIN3A.HUVEC-C 82 bp overlap

SMAD2 1 dataset

ChIP endoderm GSE29422.SMAD2.endoderm 152 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 933 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 499 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 915 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 850 bp overlap

SMAD3 1 dataset

ChIP endoderm GSE29422.SMAD3.endoderm 156 bp overlap

SMAD4 2 datasets

ChIP Caco-2 GSE112946.SMAD4.Caco-2 123 bp overlap

ChIP endoderm GSE29422.SMAD4.endoderm 155 bp overlap

SMARCA4 2 datasets

ChIP TTC-1240 GSE124903.SMARCA4.TTC-1240 379 bp overlap

ChIP hiPSC GSE124903.SMARCA4.hiPSC 159 bp overlap

SMARCC1 1 dataset

ChIP TTC-549_Dox GSE71504.SMARCC1.TTC-549_Dox 162 bp overlap

ChIP HAP1_WaplKO-33_SCC4KO GSE94992.SMC1.HAP1_WaplKO-33_SCC4KO 228 bp overlap

SNAI2 1 dataset

ChIP SMS-CTR_D48 GSE137168.SNAI2.SMS-CTR_D48 167 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 342 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 829 bp overlap

Motif DE_72h DE_72h-SP4_MA0685.2 9 bp overlap

Motif DE_72h DE_72h-SP5_MA1965.2 6 bp overlap

SPI1 2 datasets

ChIP Kasumi-1_SICTR GSE60130.SPI1.Kasumi-1_SICTR 184 bp overlap

ChIP primary-monocyte_donorA_ncMO GSE128834.SPI1.primary-monocyte_donorA_ncMO 84 bp overlap

STAT1 1 dataset

ChIP CD14_INFG_LPS GSE43036.STAT1.CD14_INFG_LPS 142 bp overlap

TCF21 1 dataset

ChIP HCASMC GSE124011.TCF21.HCASMC 296 bp overlap

TCF7L1 1 dataset

Motif DE_72h DE_72h-TCF7L1_MA1421.1 12 bp overlap

TFAP2B 1 dataset

Motif DE_72h DE_72h-TFAP2B_MA0813.1 13 bp overlap

TFAP2C 1 dataset

Motif DE_72h DE_72h-TFAP2C_MA0815.1 13 bp overlap

ChIP hESC_DAMAGED GSE39912.TP53.hESC_DAMAGED 204 bp overlap

TRPS1 1 dataset

Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap

ZBTB24 1 dataset

ChIP HCT-116 GSE111683.ZBTB24.HCT-116 239 bp overlap

ZNF121 2 datasets

ChIP HEK293 GSE76494.ZNF121.HEK293 112 bp overlap

ChIP HepG2 ENCFF343YSL 222 bp overlap

ZNF263 1 dataset

Motif DE_72h DE_72h-ZNF263_MA0528.3 7 bp overlap

ZNF274 1 dataset

Motif DE_72h DE_72h-ZNF274_MA1592.2 12 bp overlap

ZNF485 1 dataset

ChIP HEK293T GSE78099.ZNF485.HEK293T 474 bp overlap

ZNF766 1 dataset

Motif DE_72h DE_72h-ZNF766_MA2098.1 9 bp overlap

Zfp809 1 dataset

Motif DE_72h DE_72h-Zfp809_MA2125.1 9 bp overlap