chr2 : 174,925,097 – 174,925,704

607 bp 80 TFs 4 linked genes

This 607 bp open chromatin element is linked to 4 target genes and is bound by 80 transcription factors.

Linked Genes

4 genes

Gene	Dist. to TSS	Distance	Link type
CHN1	79.8 kb	Distal	Multiome
WIPF1	242.6 kb	Distal	Multiome
ATF2	242.6 kb	Distal	Multiome
ATP5MC3	256.2 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

80 transcription factors

AR 1 dataset

ChIP LNCaP-abl GSE39459.AR.LNCaP-abl 112 bp overlap

ASH2L 1 dataset

ChIP WA01 ENCSR850KIP.ASH2L.WA01 570 bp overlap

Arid3a 2 datasets

Motif DE_12h DE_12h-Arid3a_MA0151.1 6 bp overlap

Motif ES_0h ES_0h-Arid3a_MA0151.1 6 bp overlap

BCL6B 3 datasets

Motif DE_12h DE_12h-BCL6B_MA0731.1 17 bp overlap

Motif ES_0h ES_0h-BCL6B_MA0731.1 17 bp overlap

BRD4 1 dataset

ChIP HAP1 GSE108387.BRD4.HAP1 489 bp overlap

CHD7 2 datasets

ChIP H1 ENCFF126NLU 353 bp overlap

ChIP WA01 ENCSR000AVA.CHD7.WA01 266 bp overlap

CTCF 1 dataset

ChIP neuroblastoma GSE115862.CTCF.neuroblastoma 71 bp overlap

E2F7 2 datasets

Motif DE_12h DE_12h-E2F7_MA0758.1 14 bp overlap

Motif ES_0h ES_0h-E2F7_MA0758.1 14 bp overlap

EBF3 1 dataset

Motif DE_12h DE_12h-EBF3_MA1637.2 9 bp overlap

EP300 1 dataset

ChIP WA01 ENCSR000BKK.EP300.WA01 125 bp overlap

Ebf2 1 dataset

Motif DE_12h DE_12h-Ebf2_MA1604.2 9 bp overlap

FOXA1 1 dataset

ChIP CFPAC-1 GSE119930.FOXA1.CFPAC-1 55 bp overlap

FOXG1 2 datasets

Motif DE_12h DE_12h-FOXG1_MA0613.1 8 bp overlap

Motif ES_0h ES_0h-FOXG1_MA0613.1 8 bp overlap

FOXN3 2 datasets

Motif DE_12h DE_12h-FOXN3_MA1489.1 8 bp overlap

Motif ES_0h ES_0h-FOXN3_MA1489.1 8 bp overlap

FOXP1 1 dataset

ChIP H9 GSE31006.FOXP1.H9 140 bp overlap

GATA6 1 dataset

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 274 bp overlap

HDAC2 2 datasets

ChIP H1 ENCFF939VKA 237 bp overlap

ChIP WA01 ENCSR000BNR.HDAC2.WA01 297 bp overlap

HSF1 3 datasets

Motif DE_12h DE_12h-HSF1_MA0486.2 13 bp overlap

Motif ES_0h ES_0h-HSF1_MA0486.2 13 bp overlap

ChIP WA09_heat-shock GSE105028.HSF1.WA09_heat-shock 322 bp overlap

Irf1 1 dataset

Motif ES_0h ES_0h-Irf1_MA0050.4 11 bp overlap

JUN 3 datasets

ChIP DE_D1 S08-DE-d1-JUN-exp1 204 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 563 bp overlap

ChIP ESC S34-ESC-d0-JUN-exp2 320 bp overlap

MED1 1 dataset

ChIP hESC_PRIMED GSE69646.MED1.hESC_PRIMED 514 bp overlap

MEIS1 2 datasets

Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap

Motif ES_0h ES_0h-MEIS1_MA0498.3 5 bp overlap

MYB 1 dataset

Motif DE_12h DE_12h-MYB_MA0100.4 6 bp overlap

NANOG 7 datasets

ChIP GM23338 ENCFF065NZG 282 bp overlap

ChIP GM23338 ENCSR061DGF.NANOG.GM23338 187 bp overlap

ChIP HUES-8 GSE109524.NANOG.HUES-8 607 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 366 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 607 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 600 bp overlap

ChIP hESC GSE18292.NANOG.hESC 105 bp overlap

NFATC3 1 dataset

Motif DE_12h DE_12h-NFATC3_MA0625.3 6 bp overlap

NFATC4 1 dataset

Motif DE_12h DE_12h-NFATC4_MA1525.3 9 bp overlap

NIPBL 3 datasets

ChIP WA09 GSE105028.NIPBL.WA09 280 bp overlap

ChIP WA09_heat-shock GSE105028.NIPBL.WA09_heat-shock 143 bp overlap

ChIP hESC_WNT3A_ACTIVIN GSE64758.NIPBL.hESC_WNT3A_ACTIVIN 200 bp overlap

NR1I3 1 dataset

Motif DE_12h DE_12h-NR1I3_MA1534.2 8 bp overlap

Nfatc1 1 dataset

Motif DE_12h DE_12h-Nfatc1_MA0624.3 6 bp overlap

Nfatc2 1 dataset

Motif DE_12h DE_12h-Nfatc2_MA0152.3 8 bp overlap

PKNOX2 2 datasets

Motif DE_12h DE_12h-PKNOX2_MA0783.1 12 bp overlap

Motif ES_0h ES_0h-PKNOX2_MA0783.1 12 bp overlap

POU1F1 2 datasets

Motif DE_12h DE_12h-POU1F1_MA0784.3 14 bp overlap

Motif ES_0h ES_0h-POU1F1_MA0784.3 14 bp overlap

POU2F1 2 datasets

Motif DE_12h DE_12h-POU2F1_MA0785.2 9 bp overlap

Motif ES_0h ES_0h-POU2F1_MA0785.2 9 bp overlap

POU2F1::SOX2 1 dataset

Motif DE_12h DE_12h-POU2F1SOX2_MA1962.1 17 bp overlap

POU2F2 2 datasets

Motif DE_12h DE_12h-POU2F2_MA0507.3 13 bp overlap

Motif ES_0h ES_0h-POU2F2_MA0507.3 13 bp overlap

POU3F1 2 datasets

Motif DE_12h DE_12h-POU3F1_MA0786.2 10 bp overlap

Motif ES_0h ES_0h-POU3F1_MA0786.2 10 bp overlap

POU3F2 2 datasets

Motif DE_12h DE_12h-POU3F2_MA0787.1 12 bp overlap

Motif ES_0h ES_0h-POU3F2_MA0787.1 12 bp overlap

POU3F3 2 datasets

Motif DE_12h DE_12h-POU3F3_MA0788.1 13 bp overlap

Motif ES_0h ES_0h-POU3F3_MA0788.1 13 bp overlap

POU5F1 7 datasets

ChIP GM23338 ENCFF333SNB 302 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 607 bp overlap

ChIP WA09 GSE105028.POU5F1.WA09 245 bp overlap

ChIP WA09_heat-shock GSE105028.POU5F1.WA09_heat-shock 243 bp overlap

ChIP hESC ENCSR264RJX.POU5F1.hESC 185 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 252 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 607 bp overlap

POU5F1B 2 datasets

Motif DE_12h DE_12h-POU5F1B_MA0792.1 9 bp overlap

Motif ES_0h ES_0h-POU5F1B_MA0792.1 9 bp overlap

PRDM9 1 dataset

Motif ES_0h ES_0h-PRDM9_MA1723.2 20 bp overlap

Pou5f1::Sox2 1 dataset

Motif DE_12h DE_12h-Pou5f1Sox2_MA0142.1 15 bp overlap

RBPJ 1 dataset

Motif ES_0h ES_0h-RBPJ_MA1116.2 6 bp overlap

RELB 1 dataset

Motif DE_12h DE_12h-RELB_MA1117.2 7 bp overlap

SIX1 1 dataset

Motif ES_0h ES_0h-SIX1_MA1118.2 9 bp overlap

SIX2 1 dataset

Motif ES_0h ES_0h-SIX2_MA1119.2 11 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 374 bp overlap

SMAD2_3 1 dataset

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 346 bp overlap

SMARCA4 4 datasets

ChIP WA09 GSE105028.SMARCA4.WA09 446 bp overlap

ChIP WA09_heat-shock GSE105028.SMARCA4.WA09_heat-shock 270 bp overlap

ChIP hiPSC GSE124903.SMARCA4.hiPSC 519 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 448 bp overlap

SMARCB1 3 datasets

ChIP hiPSC GSE124903.SMARCB1.hiPSC 319 bp overlap

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 224 bp overlap

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 192 bp overlap

SMARCC1 2 datasets

ChIP hiPSC GSE124903.SMARCC1.hiPSC 607 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 558 bp overlap

SOX2 1 dataset

ChIP hiPSC GSE56567.SOX2.hiPSC 219 bp overlap

SOX21 1 dataset

Motif DE_12h DE_12h-SOX21_MA0866.1 15 bp overlap

SP2 1 dataset

Motif DE_12h DE_12h-SP2_MA0516.3 9 bp overlap

Six4 1 dataset

Motif ES_0h ES_0h-Six4_MA2001.2 7 bp overlap

T 1 dataset

ChIP H9_MESODERM GSE60606.T.H9_MESODERM 262 bp overlap

TAL1::TCF3 2 datasets

Motif DE_12h DE_12h-TAL1TCF3_MA0091.2 10 bp overlap

Motif ES_0h ES_0h-TAL1TCF3_MA0091.2 10 bp overlap

TBP 3 datasets

ChIP hESC GSE122298.TBP.hESC 177 bp overlap

ChIP hESC_10h GSE122298.TBP.hESC_10h 122 bp overlap

ChIP hESC_2h GSE122298.TBP.hESC_2h 273 bp overlap

TBX1 2 datasets

Motif DE_12h DE_12h-TBX1_MA0805.1 8 bp overlap

Motif ES_0h ES_0h-TBX1_MA0805.1 8 bp overlap

TBX15 2 datasets

Motif DE_12h DE_12h-TBX15_MA0803.1 8 bp overlap

Motif ES_0h ES_0h-TBX15_MA0803.1 8 bp overlap

TBX2 2 datasets

Motif DE_12h DE_12h-TBX2_MA0688.2 9 bp overlap

Motif ES_0h ES_0h-TBX2_MA0688.2 9 bp overlap

TBX21 2 datasets

Motif DE_12h DE_12h-TBX21_MA0690.3 10 bp overlap

Motif ES_0h ES_0h-TBX21_MA0690.3 10 bp overlap

TBX4 2 datasets

Motif DE_12h DE_12h-TBX4_MA0806.1 8 bp overlap

Motif ES_0h ES_0h-TBX4_MA0806.1 8 bp overlap

TBX5 2 datasets

Motif DE_12h DE_12h-TBX5_MA0807.1 8 bp overlap

Motif ES_0h ES_0h-TBX5_MA0807.1 8 bp overlap

TCF3 1 dataset

ChIP NPC GSE154479.TCF3.NPC 259 bp overlap

TEAD1 1 dataset

ChIP WTC11 ENCFF502QUV 401 bp overlap

TEAD4 2 datasets

ChIP ESC S26-ESC-d0-TEAD4-exp1 478 bp overlap

ChIP hESC GSE99202.TEAD4.hESC 348 bp overlap

TFAP2C 3 datasets

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 116 bp overlap

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 317 bp overlap

ChIP UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc 60 bp overlap

TGIF1 2 datasets

Motif DE_12h DE_12h-TGIF1_MA0796.1 12 bp overlap

Motif ES_0h ES_0h-TGIF1_MA0796.1 12 bp overlap

TGIF2 2 datasets

Motif DE_12h DE_12h-TGIF2_MA0797.1 12 bp overlap

Motif ES_0h ES_0h-TGIF2_MA0797.1 12 bp overlap

TP53 1 dataset

ChIP H9_ectoderm GSE142050.TP53.H9_ectoderm 546 bp overlap

ZKSCAN5 1 dataset

Motif ES_0h ES_0h-ZKSCAN5_MA1652.2 9 bp overlap

ZNF136 2 datasets

Motif DE_12h DE_12h-ZNF136_MA1588.1 15 bp overlap

Motif ES_0h ES_0h-ZNF136_MA1588.1 15 bp overlap

ZNF143 1 dataset

Motif ES_0h ES_0h-ZNF143_MA0088.2 16 bp overlap

ZNF462 3 datasets

ChIP GM23338 ENCFF896CCA 251 bp overlap

ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 197 bp overlap

ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 303 bp overlap

ZNF528 1 dataset

Motif DE_12h DE_12h-ZNF528_MA1597.1 17 bp overlap

ZNF677 1 dataset

Motif DE_12h DE_12h-ZNF677_MA2101.1 12 bp overlap

ZNF684 2 datasets

Motif DE_12h DE_12h-ZNF684_MA1600.2 14 bp overlap

ZNF766 1 dataset

Motif ES_0h ES_0h-ZNF766_MA2098.1 9 bp overlap

Zfx 1 dataset

Motif DE_12h DE_12h-Zfx_MA0146.3 10 bp overlap