chr2:44,930,118–44,930,479

chr2 : 44,930,118 – 44,930,479

361 bp 64 TFs 6 linked genes

This 361 bp open chromatin element is linked to 6 target genes and is bound by 64 transcription factors.

Linked Genes

6 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000278957		1.7 kb	Proximal	Proximity
ENSG00000276229		4.8 kb	Proximal	Proximity
ENSG00000277809		5.1 kb	Proximal	Proximity
LINC01833		5.3 kb	Proximal	Proximity
ENSG00000276048		6.9 kb	Proximal	Proximity
ENSG00000274547		8.4 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

64 transcription factors

ChIP prostate_fetal-fibroblast GSE90772.AR.prostate_fetal-fibroblast 221 bp overlap

ASH2L 2 datasets

ChIP H1 ENCFF399KAM 299 bp overlap

ChIP WA01 ENCSR850KIP.ASH2L.WA01 361 bp overlap

ChIP HUES-64 GSE104059.BRD1.HUES-64 361 bp overlap

ChIP MV4-11-B_BI00894999_35nM_4h GSE101821.BRD4.MV4-11-B_BI00894999_35nM_4h 136 bp overlap

ChIP K-562 ENCSR000ATU.CBX2.K-562 61 bp overlap

ChIP hMSC GSE117084.CBX4.hMSC 171 bp overlap

CBX7 4 datasets

ChIP HEK293T_PCGF2fl GSE119618.CBX7.HEK293T_PCGF2fl 192 bp overlap

ChIP hESC GSE133412.CBX7.hESC 211 bp overlap

ChIP hESC_QKO GSE133412.CBX7.hESC_QKO 187 bp overlap

ChIP hESC_TKO GSE133412.CBX7.hESC_TKO 217 bp overlap

CDK9 2 datasets

ChIP HCT-116 GSE72622.CDK9.HCT-116 156 bp overlap

ChIP MM1-S_JQ1_500NM GSE42355.CDK9.MM1-S_JQ1_500NM 107 bp overlap

CDKN1B 1 dataset

ChIP MDA-MB-231 GSE112444.CDKN1B.MDA-MB-231 230 bp overlap

CTBP2 2 datasets

ChIP H1 ENCFF329MAX 289 bp overlap

ChIP WA01 ENCSR000EUO.CTBP2.WA01 361 bp overlap

ChIP thyroid-gland ENCSR744YJR.CTCF.thyroid-gland 102 bp overlap

Cebpa 3 datasets

ChIP BLaER1 ENCFF335XTP 152 bp overlap

ChIP BLaER1 ENCFF364PUR 112 bp overlap

ChIP BLaER1 ENCFF460KDD 251 bp overlap

ChIP ProEs GSE59087.EED.ProEs 113 bp overlap

EP300 1 dataset

ChIP AML GSE131939.EP300.AML 155 bp overlap

ChIP TSU-1621MT GSE60477.ERG.TSU-1621MT 236 bp overlap

ChIP TSU-1621MT_ATRA GSE60477.ERG.TSU-1621MT_ATRA 270 bp overlap

ETS1 5 datasets

ChIP GM23338 ENCFF701IZH 235 bp overlap

ChIP HUVEC-C_12h GSE93030.ETS1.HUVEC-C_12h 152 bp overlap

ChIP HUVEC-C_VEGF_12H GSE41166.ETS1.HUVEC-C_VEGF_12H 196 bp overlap

ChIP HUVEC-C_VEGF_12h GSE109625.ETS1.HUVEC-C_VEGF_12h 152 bp overlap

ChIP hESC ENCSR534VHI.ETS1.hESC 144 bp overlap

EZH2 29 datasets

ChIP A673 ENCFF790MVL 300 bp overlap

ChIP A673 ENCFF790MVL 173 bp overlap

ChIP A673 ENCFF955JRZ 300 bp overlap

ChIP A673 ENCFF955JRZ 181 bp overlap

ChIP B-cell ENCSR000AUZ.EZH2.B-cell 361 bp overlap

ChIP GM23248 ENCFF404ZHM 86 bp overlap

ChIP GM23248 ENCFF404ZHM 106 bp overlap

ChIP GM23248 ENCFF404ZHM 53 bp overlap

ChIP GM23248 ENCFF506FWX 181 bp overlap

ChIP GM23248 ENCFF506FWX 304 bp overlap

ChIP GM23248 ENCFF506FWX 57 bp overlap

ChIP GM23338 ENCFF613YON 361 bp overlap

ChIP H1 ENCFF232NZA 361 bp overlap

ChIP astrocyte ENCFF365JTP 361 bp overlap

ChIP dermal-fibroblast_Preneoplastic GSE126396.EZH2.dermal-fibroblast_Preneoplastic 361 bp overlap

ChIP dermal-fibroblast_Transformed GSE126396.EZH2.dermal-fibroblast_Transformed 361 bp overlap

ChIP dermal-fibroblast_Untransformed GSE126396.EZH2.dermal-fibroblast_Untransformed 103 bp overlap

ChIP dermal-fibroblast_Untransformed GSE126396.EZH2.dermal-fibroblast_Untransformed 152 bp overlap

ChIP endothelial cell of umbilical vein ENCFF539AKL 361 bp overlap

ChIP fibroblast of dermis ENCFF029VZK 361 bp overlap

ChIP fibroblast of lung ENCFF479BAW 204 bp overlap

ChIP fibroblast of lung ENCFF479BAW 361 bp overlap

ChIP hepatocyte ENCFF118DKH 82 bp overlap

ChIP hepatocyte ENCFF552DZB 361 bp overlap

ChIP keratinocyte ENCFF070STK 343 bp overlap

ChIP keratinocyte ENCFF070STK 361 bp overlap

ChIP neural progenitor cell ENCFF018MKA 118 bp overlap

ChIP neural progenitor cell ENCFF018MKA 213 bp overlap

ChIP neural progenitor cell ENCFF472NFV 361 bp overlap

FLI1 2 datasets

ChIP HUVEC-C GSE109695.FLI1.HUVEC-C 131 bp overlap

ChIP SK-N-MC_SHGFP_96H GSE61944.FLI1.SK-N-MC_SHGFP_96H 281 bp overlap

GABPA 2 datasets

ChIP H1 ENCFF739QFD 230 bp overlap

ChIP WA01 ENCSR000BIW.GABPA.WA01 269 bp overlap

GATA2 1 dataset

ChIP SKH1 GSE87283.GATA2.SKH1 134 bp overlap

GATA6 4 datasets

ChIP DE_D1 S14-DE-d1-GATA6-exp1 88 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 134 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 361 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 361 bp overlap

HDAC6 1 dataset

ChIP GM12878 ENCSR933EYC.HDAC6.GM12878 176 bp overlap

HEXIM1 1 dataset

ChIP HCT-116 GSE72622.HEXIM1.HCT-116 115 bp overlap

HIVEP1 1 dataset

ChIP Hep-G2 ENCSR697WMX.HIVEP1.Hep-G2 193 bp overlap

INO80 1 dataset

ChIP Huh-7 GSE97411.INO80.Huh-7 251 bp overlap

ChIP T-cell GSE136853.IRF4.T-cell 150 bp overlap

JARID2 3 datasets

ChIP AMIPS8 GSE48516.JARID2.AMIPS8 111 bp overlap

ChIP hESC GSE133412.JARID2.hESC 164 bp overlap

ChIP hESC_TKO GSE133412.JARID2.hESC_TKO 178 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 361 bp overlap

ChIP ESC S34-ESC-d0-JUN-exp2 236 bp overlap

ChIP HUES-8 GSE109524.JUN.HUES-8 211 bp overlap

ChIP MDA-BoM-1833 GSE112444.JUN.MDA-BoM-1833 186 bp overlap

KDM5B 1 dataset

ChIP HCC2157 GSE46055.KDM5B.HCC2157 146 bp overlap

ChIP TSU-1621MT GSE60477.LMO2.TSU-1621MT 189 bp overlap

ChIP Jurkat GSE83777.MYC.Jurkat 176 bp overlap

ChIP LA-N-5 GSE138295.MYCN.LA-N-5 65 bp overlap

NANOG 6 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 361 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 200 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 117 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 361 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 334 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 168 bp overlap

Motif DE_12h DE_12h-Nrf1_MA0506.3 12 bp overlap

OGG1 2 datasets

ChIP HEK293 GSE89017.OGG1.HEK293 140 bp overlap

ChIP HEK293_60_min GSE89017.OGG1.HEK293_60_min 123 bp overlap

ChIP retina_pigment GSE60024.PAX6.retina_pigment 202 bp overlap

PCGF2 3 datasets

ChIP HEK293T_PCGF2fl GSE119618.PCGF2.HEK293T_PCGF2fl 181 bp overlap

ChIP NT2-D1 GSE101538.PCGF2.NT2-D1 334 bp overlap

ChIP fibroblast_OHT GSE55605.PCGF2.fibroblast_OHT 225 bp overlap

POU5F1 2 datasets

ChIP DE_D1 DED1-OCT4_Batch_II 270 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 107 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 289 bp overlap

ChIP U-937_ATRA-treated_RAR GSE98006.RARA.U-937_ATRA-treated_RAR 184 bp overlap

RBBP5 2 datasets

ChIP WA01 ENCSR000AQC.RBBP5.WA01 148 bp overlap

ChIP WA01 ENCSR000AQC.RBBP5.WA01 158 bp overlap

RNF2 4 datasets

ChIP H1 ENCFF239FFS 361 bp overlap

ChIP HEK293T_PCGF135fl_OHT GSE119618.RNF2.HEK293T_PCGF135fl_OHT 69 bp overlap

ChIP HEK293T_PCGF2fl GSE119618.RNF2.HEK293T_PCGF2fl 88 bp overlap

ChIP NCCIT GSE71675.RNF2.NCCIT 361 bp overlap

RUNX1T1 1 dataset

ChIP Kasumi-1 GSE115115.RUNX1T1.Kasumi-1 361 bp overlap

SIN3A 2 datasets

ChIP H1 ENCFF042ZSL 167 bp overlap

ChIP WA01 ENCSR000EBO.SIN3A.WA01 120 bp overlap

SMAD2 1 dataset

ChIP hESC_YAP-_activinA_15h GSE99202.SMAD2.hESC_YAP-_activinA_15h 125 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 361 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 146 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 83 bp overlap

SMAD2_3 3 datasets

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 55 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 103 bp overlap

ChIP ESC S33-ESC-d0-SMAD2_3-exp2 292 bp overlap

SMAD3 1 dataset

ChIP hESC GSE29422.SMAD3.hESC 155 bp overlap

SMARCC1 2 datasets

ChIP SK-N-MC GSE94275.SMARCC1.SK-N-MC 50 bp overlap

ChIP SK-N-MC_shEWSFLI1 GSE94275.SMARCC1.SK-N-MC_shEWSFLI1 275 bp overlap

ChIP WA01 ENCSR000BIR.SP1.WA01 287 bp overlap

ChIP CD34_FETAL GSE70660.SPI1.CD34_FETAL 128 bp overlap

SREBP2 1 dataset

ChIP HCC70 GSE126380.SREBP2.HCC70 165 bp overlap

SS18-SSX 1 dataset

ChIP fibroblast_78aa-SSX-Tail GSE139053.SS18-SSX.fibroblast_78aa-SSX-Tail 110 bp overlap

SUZ12 10 datasets

ChIP GM12878 ENCSR744XTG.SUZ12.GM12878 256 bp overlap

ChIP GM12878 ENCSR091BOQ.SUZ12.GM12878 204 bp overlap

ChIP H1 ENCFF507HGF 257 bp overlap

ChIP H1 ENCFF881NFR 361 bp overlap

ChIP HEK293T_PCGF135fl GSE119618.SUZ12.HEK293T_PCGF135fl 151 bp overlap

ChIP HEK293T_PCGF135fl_OHT GSE119618.SUZ12.HEK293T_PCGF135fl_OHT 176 bp overlap

ChIP HEK293T_PCGF2fl GSE119618.SUZ12.HEK293T_PCGF2fl 190 bp overlap

ChIP HEK293T_PCGF2fl_OHT GSE119618.SUZ12.HEK293T_PCGF2fl_OHT 187 bp overlap

ChIP NT2/D1 ENCFF574SXS 361 bp overlap

ChIP WA01 ENCSR000EUQ.SUZ12.WA01 277 bp overlap

ChIP TSU-1621MT GSE60477.TAL1.TSU-1621MT 172 bp overlap

TCF12 1 dataset

ChIP WA01 ENCSR000BIT.TCF12.WA01 291 bp overlap

ChIP Kasumi-1 GSE43834.TCF3.Kasumi-1 176 bp overlap

TCF7L2 1 dataset

ChIP CD34_PROG_BIO GSE29194.TCF7L2.CD34_PROG_BIO 177 bp overlap

TEAD4 1 dataset

ChIP ESC S26-ESC-d0-TEAD4-exp1 361 bp overlap

ZBTB48 1 dataset

ChIP U2OS_ZBTB48-KO GSE96776.ZBTB48.U2OS_ZBTB48-KO 215 bp overlap

ZKSCAN5 1 dataset

Motif DE_12h DE_12h-ZKSCAN5_MA1652.2 9 bp overlap

ZNF304 1 dataset

ChIP HEK293T GSE78099.ZNF304.HEK293T 180 bp overlap

ZNF692 1 dataset

Motif DE_12h DE_12h-ZNF692_MA1986.2 8 bp overlap

Zfp809 1 dataset

Motif DE_12h DE_12h-Zfp809_MA2125.1 9 bp overlap