chr18 : 26,233,162 – 26,233,905

743 bp 110 TFs 2 linked genes

This 743 bp open chromatin element is linked to TAF4B and SS18 and is bound by 110 transcription factors.

Linked Genes

2 genes

Gene	Expression	Dist. to TSS	Distance	Link type
TAF4B		6.7 kb	Proximal	Proximity
SS18		142.8 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

110 transcription factors

ALX3 1 dataset

Motif ES_0h ES_0h-ALX3_MA0634.2 6 bp overlap

CTBP2 1 dataset

ChIP WA01 ENCSR000EUO.CTBP2.WA01 248 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF460KDD 195 bp overlap

DRGX 1 dataset

Motif ES_0h ES_0h-DRGX_MA1481.2 6 bp overlap

EMX1 1 dataset

Motif ES_0h ES_0h-EMX1_MA0612.3 6 bp overlap

EMX2 1 dataset

Motif ES_0h ES_0h-EMX2_MA0886.2 6 bp overlap

EN1 1 dataset

Motif ES_0h ES_0h-EN1_MA0027.3 6 bp overlap

EP300 1 dataset

ChIP H1 ENCFF927IYK 297 bp overlap

ETV5::HOXA2 1 dataset

Motif ES_0h ES_0h-ETV5HOXA2_MA1948.2 12 bp overlap

ETV6 1 dataset

ChIP WTC11 ENCFF812SCD 437 bp overlap

EVX1 1 dataset

Motif ES_0h ES_0h-EVX1_MA0887.2 6 bp overlap

EVX2 1 dataset

Motif ES_0h ES_0h-EVX2_MA0888.2 6 bp overlap

FOXE1 2 datasets

Motif DE_12h DE_12h-FOXE1_MA1487.3 12 bp overlap

Motif ES_0h ES_0h-FOXE1_MA1487.3 12 bp overlap

Foxq1 2 datasets

Motif DE_12h DE_12h-Foxq1_MA0040.2 10 bp overlap

Motif ES_0h ES_0h-Foxq1_MA0040.2 10 bp overlap

GATA6 7 datasets

ChIP DE DE-GATA6-2 299 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 348 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 514 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 516 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 292 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 340 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 378 bp overlap

GLIS1 1 dataset

ChIP HEK293 ENCFF299RSE 244 bp overlap

GLIS2 2 datasets

Motif DE_12h DE_12h-GLIS2_MA0736.1 14 bp overlap

Motif ES_0h ES_0h-GLIS2_MA0736.1 14 bp overlap

GSX1 1 dataset

Motif ES_0h ES_0h-GSX1_MA0892.2 6 bp overlap

GSX2 1 dataset

Motif ES_0h ES_0h-GSX2_MA0893.3 7 bp overlap

HDAC2 1 dataset

ChIP H1 ENCFF939VKA 237 bp overlap

HNF4A 2 datasets

Motif DE_12h DE_12h-HNF4A_MA1494.2 14 bp overlap

Motif ES_0h ES_0h-HNF4A_MA1494.2 14 bp overlap

HOXA1 1 dataset

Motif ES_0h ES_0h-HOXA1_MA1495.2 6 bp overlap

HOXA2 1 dataset

Motif ES_0h ES_0h-HOXA2_MA0900.3 6 bp overlap

HOXA3 1 dataset

Motif ES_0h ES_0h-HOXA3_MA2119.1 7 bp overlap

HOXA6 1 dataset

Motif ES_0h ES_0h-HOXA6_MA1497.2 7 bp overlap

HOXB1 1 dataset

Motif ES_0h ES_0h-HOXB1_MA2093.1 7 bp overlap

HOXB2 1 dataset

Motif ES_0h ES_0h-HOXB2_MA0902.3 6 bp overlap

HOXB3 1 dataset

Motif ES_0h ES_0h-HOXB3_MA0903.2 6 bp overlap

HOXB5 1 dataset

Motif ES_0h ES_0h-HOXB5_MA0904.3 6 bp overlap

HOXB6 1 dataset

Motif ES_0h ES_0h-HOXB6_MA1500.2 7 bp overlap

HOXB7 1 dataset

Motif ES_0h ES_0h-HOXB7_MA1501.2 7 bp overlap

HOXB8 1 dataset

Motif ES_0h ES_0h-HOXB8_MA1502.2 7 bp overlap

HOXC8 1 dataset

Motif ES_0h ES_0h-HOXC8_MA1505.2 6 bp overlap

HOXD8 1 dataset

Motif ES_0h ES_0h-HOXD8_MA0910.3 7 bp overlap

ISX 1 dataset

Motif ES_0h ES_0h-ISX_MA0654.2 6 bp overlap

JUN 7 datasets

ChIP DE_D1 S08-DE-d1-JUN-exp1 423 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 503 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 740 bp overlap

ChIP ESC S24-ESC-d0-JUN-exp1 370 bp overlap

ChIP ESC S34-ESC-d0-JUN-exp2 567 bp overlap

ChIP HUES-8 GSE109524.JUN.HUES-8 365 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 366 bp overlap

KDM1A 1 dataset

ChIP H1 ENCFF696SGD 481 bp overlap

LHX5 1 dataset

Motif ES_0h ES_0h-LHX5_MA1519.2 7 bp overlap

Lhx4 1 dataset

Motif ES_0h ES_0h-Lhx4_MA0704.2 6 bp overlap

Lhx8 1 dataset

Motif ES_0h ES_0h-Lhx8_MA0705.2 6 bp overlap

MAFF 1 dataset

Motif ES_0h ES_0h-MAFF_MA0495.4 11 bp overlap

MEIS1 2 datasets

Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap

Motif ES_0h ES_0h-MEIS1_MA0498.3 5 bp overlap

MEOX1 1 dataset

Motif ES_0h ES_0h-MEOX1_MA0661.2 7 bp overlap

MEOX2 1 dataset

Motif ES_0h ES_0h-MEOX2_MA0706.2 7 bp overlap

MIXL1 1 dataset

Motif ES_0h ES_0h-MIXL1_MA0662.2 6 bp overlap

MNX1 1 dataset

Motif ES_0h ES_0h-MNX1_MA0707.3 6 bp overlap

Mafb 1 dataset

Motif ES_0h ES_0h-Mafb_MA0117.3 11 bp overlap

NANOG 4 datasets

ChIP H1 ENCFF747ZPQ 241 bp overlap

ChIP HUES-8 GSE109524.NANOG.HUES-8 356 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 178 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 557 bp overlap

NKX6-2 1 dataset

Motif ES_0h ES_0h-NKX6-2_MA0675.2 6 bp overlap

NR1H2::RXRA 2 datasets

Motif DE_12h DE_12h-NR1H2RXRA_MA0115.1 17 bp overlap

Motif ES_0h ES_0h-NR1H2RXRA_MA0115.1 17 bp overlap

NR2C2 2 datasets

Motif DE_12h DE_12h-NR2C2_MA0504.2 14 bp overlap

Motif ES_0h ES_0h-NR2C2_MA0504.2 14 bp overlap

NR2F1 2 datasets

Motif DE_12h DE_12h-NR2F1_MA1537.2 13 bp overlap

Motif ES_0h ES_0h-NR2F1_MA1537.2 13 bp overlap

NRL 1 dataset

Motif ES_0h ES_0h-NRL_MA0842.3 12 bp overlap

Nr2F6 2 datasets

Motif DE_12h DE_12h-Nr2F6_MA0728.1 15 bp overlap

Motif ES_0h ES_0h-Nr2F6_MA0728.1 15 bp overlap

Nr2f6 2 datasets

Motif DE_12h DE_12h-Nr2f6_MA0677.2 13 bp overlap

Motif ES_0h ES_0h-Nr2f6_MA0677.2 13 bp overlap

PATZ1 2 datasets

Motif DE_12h DE_12h-PATZ1_MA1961.2 11 bp overlap

Motif ES_0h ES_0h-PATZ1_MA1961.2 11 bp overlap

PAX5 2 datasets

Motif DE_12h DE_12h-PAX5_MA0014.4 8 bp overlap

Motif ES_0h ES_0h-PAX5_MA0014.4 8 bp overlap

PDX1 1 dataset

Motif ES_0h ES_0h-PDX1_MA0132.3 6 bp overlap

PLAG1 2 datasets

Motif DE_12h DE_12h-PLAG1_MA0163.1 14 bp overlap

Motif ES_0h ES_0h-PLAG1_MA0163.1 14 bp overlap

POU1F1 1 dataset

Motif ES_0h ES_0h-POU1F1_MA0784.3 14 bp overlap

POU2F1 1 dataset

Motif ES_0h ES_0h-POU2F1_MA0785.2 9 bp overlap

POU2F1::SOX2 2 datasets

Motif DE_12h DE_12h-POU2F1SOX2_MA1962.1 17 bp overlap

Motif ES_0h ES_0h-POU2F1SOX2_MA1962.1 17 bp overlap

POU2F2 1 dataset

Motif ES_0h ES_0h-POU2F2_MA0507.3 13 bp overlap

POU3F1 1 dataset

Motif ES_0h ES_0h-POU3F1_MA0786.2 10 bp overlap

POU3F2 1 dataset

Motif ES_0h ES_0h-POU3F2_MA0787.1 12 bp overlap

POU3F3 1 dataset

Motif ES_0h ES_0h-POU3F3_MA0788.1 13 bp overlap

POU3F4 1 dataset

Motif ES_0h ES_0h-POU3F4_MA0789.1 9 bp overlap

POU5F1 1 dataset

ChIP DE_D1 DED1-OCT4_Batch_II 308 bp overlap

POU5F1B 1 dataset

Motif ES_0h ES_0h-POU5F1B_MA0792.1 9 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 418 bp overlap

POU6F1 1 dataset

Motif ES_0h ES_0h-POU6F1_MA0628.2 6 bp overlap

PPARA::RXRA 2 datasets

Motif DE_12h DE_12h-PPARARXRA_MA1148.2 17 bp overlap

Motif ES_0h ES_0h-PPARARXRA_MA1148.2 17 bp overlap

PPARD 2 datasets

Motif DE_12h DE_12h-PPARD_MA1550.2 14 bp overlap

Motif ES_0h ES_0h-PPARD_MA1550.2 14 bp overlap

PRRX1 1 dataset

Motif ES_0h ES_0h-PRRX1_MA0716.2 6 bp overlap

Pou5f1::Sox2 2 datasets

Motif DE_12h DE_12h-Pou5f1Sox2_MA0142.1 15 bp overlap

Motif ES_0h ES_0h-Pou5f1Sox2_MA0142.1 15 bp overlap

Prdm15 2 datasets

Motif DE_12h DE_12h-Prdm15_MA1616.2 11 bp overlap

Motif ES_0h ES_0h-Prdm15_MA1616.2 11 bp overlap

RARA 2 datasets

Motif DE_12h DE_12h-RARA_MA0729.1 18 bp overlap

Motif ES_0h ES_0h-RARA_MA0729.1 18 bp overlap

RAX2 1 dataset

Motif ES_0h ES_0h-RAX2_MA0717.2 6 bp overlap

RFX1 2 datasets

Motif DE_12h DE_12h-RFX1_MA0509.3 16 bp overlap

Motif ES_0h ES_0h-RFX1_MA0509.3 16 bp overlap

RFX3 2 datasets

Motif DE_12h DE_12h-RFX3_MA0798.3 16 bp overlap

Motif ES_0h ES_0h-RFX3_MA0798.3 16 bp overlap

RFX5 2 datasets

Motif DE_12h DE_12h-RFX5_MA0510.3 14 bp overlap

Motif ES_0h ES_0h-RFX5_MA0510.3 14 bp overlap

RXRB 2 datasets

Motif DE_12h DE_12h-RXRB_MA0855.1 14 bp overlap

Motif ES_0h ES_0h-RXRB_MA0855.1 14 bp overlap

RXRG 2 datasets

Motif DE_12h DE_12h-RXRG_MA0856.1 14 bp overlap

Motif ES_0h ES_0h-RXRG_MA0856.1 14 bp overlap

Rarb 2 datasets

Motif DE_12h DE_12h-Rarb_MA0857.1 16 bp overlap

Motif ES_0h ES_0h-Rarb_MA0857.1 16 bp overlap

Rarg 2 datasets

Motif DE_12h DE_12h-Rarg_MA0859.2 15 bp overlap

Motif ES_0h ES_0h-Rarg_MA0859.2 15 bp overlap

Rxra 2 datasets

Motif DE_12h DE_12h-Rxra_MA0512.2 14 bp overlap

Motif ES_0h ES_0h-Rxra_MA0512.2 14 bp overlap

SHOX 1 dataset

Motif ES_0h ES_0h-SHOX_MA0630.2 6 bp overlap

SMAD2_3 2 datasets

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 289 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 444 bp overlap

SMAD3 1 dataset

ChIP BG03_DIFF_2H GSE36578.SMAD3.BG03_DIFF_2H 183 bp overlap

SP1 1 dataset

ChIP H1 ENCFF263FUH 321 bp overlap

SP7 2 datasets

ChIP HEK293 ENCFF733RBE 494 bp overlap

ChIP HEK293 ENCSR468IJT.SP7.HEK293 244 bp overlap

SPI1 6 datasets

ChIP GM12891 ENCFF563IUT 241 bp overlap

ChIP HL-60 ENCFF645GBT 271 bp overlap

ChIP K-562 ENCSR000BGW.SPI1.K-562 116 bp overlap

ChIP K562 ENCFF410ORC 205 bp overlap

Shox2 1 dataset

Motif ES_0h ES_0h-Shox2_MA0720.2 6 bp overlap

THRB 2 datasets

Motif DE_12h DE_12h-THRB_MA1574.2 13 bp overlap

Motif ES_0h ES_0h-THRB_MA1574.2 13 bp overlap

TLX2 1 dataset

Motif ES_0h ES_0h-TLX2_MA1577.2 6 bp overlap

TP63 2 datasets

ChIP keratinocyte_D0 GSE59824.TP63.keratinocyte_D0 196 bp overlap

ChIP keratinocyte_D2 GSE59824.TP63.keratinocyte_D2 256 bp overlap

UNCX 1 dataset

Motif ES_0h ES_0h-UNCX_MA0721.2 6 bp overlap

VAX2 1 dataset

Motif ES_0h ES_0h-VAX2_MA0723.3 6 bp overlap

WT1 1 dataset

ChIP HEK293 ENCFF906HIR 425 bp overlap

Wt1 2 datasets

Motif DE_12h DE_12h-Wt1_MA1627.2 10 bp overlap

Motif ES_0h ES_0h-Wt1_MA1627.2 10 bp overlap

YY1 1 dataset

ChIP H1 ENCFF524BTL 337 bp overlap

ZBTB18 2 datasets

Motif DE_12h DE_12h-ZBTB18_MA0698.2 11 bp overlap

Motif ES_0h ES_0h-ZBTB18_MA0698.2 11 bp overlap

ZBTB8A 1 dataset

ChIP HEK293 ENCFF303WRD 571 bp overlap

ZIC1 2 datasets

Motif DE_12h DE_12h-ZIC1_MA0696.1 14 bp overlap

Motif ES_0h ES_0h-ZIC1_MA0696.1 14 bp overlap

ZIC4 2 datasets

Motif DE_12h DE_12h-ZIC4_MA0751.2 14 bp overlap

Motif ES_0h ES_0h-ZIC4_MA0751.2 14 bp overlap

ZNF114 1 dataset

ChIP GM23338 ENCFF631OSW 279 bp overlap

ZNF157 1 dataset

Motif ES_0h ES_0h-ZNF157_MA2331.1 21 bp overlap

ZNF423 1 dataset

ChIP WTC11 ENCFF574PBR 317 bp overlap

ZNF462 1 dataset

ChIP GM23338 ENCFF896CCA 251 bp overlap

mix-a 1 dataset

Motif ES_0h ES_0h-mix-a_MA0621.2 7 bp overlap