chr16 : 25,148,364 – 25,149,417
1,053 bp 104 TFs 5 linked genes
This 1.1 kb open chromatin element is linked to 5 target genes and is bound by 104 transcription factors.
Linked Genes
5 genes
Distance
Link type
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
LCMT1-AS2 at TSS At TSS Proximity
LCMT1 37.2 kb Distal Multiome
ZKSCAN2 108.7 kb Distal Multiome
ZKSCAN2-DT 109.0 kb Distal Multiome
ARHGAP17 133.5 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr16:25,143,364 – 25,154,417
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
104 transcription factors
Source
Cell type
AR 1 dataset
ChIP MDA-MB-453 ERP003503.AR.MDA-MB-453 152 bp overlap
BCOR 1 dataset
ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 519 bp overlap
BRD3 2 datasets
ChIP K-562_DMSO-IFNG GSE138084.BRD3.K-562_DMSO-IFNG 259 bp overlap
ChIP K-562_iBET-BD1-IFNG GSE138084.BRD3.K-562_iBET-BD1-IFNG 295 bp overlap
BRD4 1 dataset
ChIP HEK293T GSE51633.BRD4.HEK293T 160 bp overlap
BRD9 1 dataset
ChIP G-401 GSE120234.BRD9.G-401 775 bp overlap
CTCF 8 datasets
Motif DE_24h DE_24h-CTCF_MA1929.2 31 bp overlap
Motif DE_36h DE_36h-CTCF_MA0139.2 15 bp overlap
Motif DE_36h DE_36h-CTCF_MA1929.2 31 bp overlap
Motif DE_72h DE_72h-CTCF_MA0139.2 15 bp overlap
Motif DE_72h DE_72h-CTCF_MA1929.2 31 bp overlap
Motif DE_72h DE_72h-CTCF_MA1929.2 31 bp overlap
ChIP choroid plexus epithelial cell ENCFF407YNR 277 bp overlap
ChIP choroid-plexus_epithelial ENCSR000DTL.CTCF.choroid-plexus_epithelial 141 bp overlap
Cebpa 2 datasets
ChIP BLaER1 ENCFF031ISE 328 bp overlap
ChIP BLaER1 ENCFF274GAT 515 bp overlap
DPRX 1 dataset
Motif DE_72h DE_72h-DPRX_MA1480.2 9 bp overlap
E2F6 4 datasets
Motif DE_24h DE_24h-E2F6_MA0471.3 8 bp overlap
Motif DE_36h DE_36h-E2F6_MA0471.3 8 bp overlap
Motif DE_48h DE_48h-E2F6_MA0471.3 8 bp overlap
Motif DE_72h DE_72h-E2F6_MA0471.3 8 bp overlap
ELF1 1 dataset
ChIP GM12878 ENCSR000BMB.ELF1.GM12878 148 bp overlap
EOMES 2 datasets
ChIP hESC GSE26097.EOMES.hESC 228 bp overlap
ChIP hESC GSE26097.EOMES.hESC 179 bp overlap
ESR1 4 datasets
ChIP Ishikawa_ETV4-KO2_Mili GSE129803.ESR1.Ishikawa_ETV4-KO2_Mili 172 bp overlap
ChIP MCF-7 GSE48930.ESR1.MCF-7 235 bp overlap
ChIP MCF-7_PaPE-1_OA GSE93510.ESR1.MCF-7_PaPE-1_OA 485 bp overlap
ChIP MCF-7_Veh_OA GSE93510.ESR1.MCF-7_Veh_OA 448 bp overlap
ESR1_Y537S 1 dataset
ChIP MCF-7_E2 GSE94493.ESR1_Y537S.MCF-7_E2 227 bp overlap
ESR1_pS118 1 dataset
ChIP MCF-7_E2_sc GSE117569.ESR1_pS118.MCF-7_E2_sc 535 bp overlap
ESR2 2 datasets
Motif DE_36h DE_36h-ESR2_MA0258.2 15 bp overlap
Motif DE_72h DE_72h-ESR2_MA0258.2 15 bp overlap
EZH2 1 dataset
ChIP RH30_DMSO GSE85169.EZH2.RH30_DMSO 243 bp overlap
FEZF2 2 datasets
Motif DE_36h DE_36h-FEZF2_MA2341.1 8 bp overlap
Motif DE_72h DE_72h-FEZF2_MA2341.1 8 bp overlap
FIGLA 2 datasets
Motif DE_36h DE_36h-FIGLA_MA0820.2 6 bp overlap
Motif DE_72h DE_72h-FIGLA_MA0820.2 6 bp overlap
FIP1L1 1 dataset
ChIP Hep-G2 ENCSR313VZG.FIP1L1.Hep-G2 218 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 406 bp overlap
ChIP DE DE-FOXA2-2 402 bp overlap
FOXN3 3 datasets
Motif DE_24h DE_24h-FOXN3_MA1489.1 8 bp overlap
Motif DE_48h DE_48h-FOXN3_MA1489.1 8 bp overlap
Motif DE_72h DE_72h-FOXN3_MA1489.1 8 bp overlap
GATA1 2 datasets
ChIP K-562 GSE107726.GATA1.K-562 164 bp overlap
ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 142 bp overlap
GATA2 5 datasets
ChIP ME-1_CBFB-MYH11-KD GSE117138.GATA2.ME-1_CBFB-MYH11-KD 475 bp overlap
ChIP SH-SY5Y ENCFF485YIB 405 bp overlap
ChIP SH-SY5Y ENCSR000EYB.GATA2.SH-SY5Y 418 bp overlap
ChIP SK-N-SH ENCSR706VOO.GATA2.SK-N-SH 171 bp overlap
ChIP hiPSC_SLC6ebs GSE107639.GATA2.hiPSC_SLC6ebs 419 bp overlap
GATA3 1 dataset
ChIP Kelly GSE65664.GATA3.Kelly 195 bp overlap
GATA3_Nter 1 dataset
ChIP T-47D_CR3flp GSE99479.GATA3_Nter.T-47D_CR3flp 356 bp overlap
GATA4 5 datasets
ChIP DE DE-GATA4-1 780 bp overlap
ChIP DE DE-GATA4-2 745 bp overlap
ChIP foregut GSE117136.GATA4.foregut 519 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 305 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 431 bp overlap
GATA6 11 datasets
ChIP DE DE-GATA6-1 694 bp overlap
ChIP DE DE-GATA6-2 758 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 659 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 819 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 702 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 724 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 875 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 736 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 753 bp overlap
ChIP foregut GSE117136.GATA6.foregut 383 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 534 bp overlap
GCM2 2 datasets
Motif DE_36h DE_36h-GCM2_MA0767.2 8 bp overlap
Motif DE_72h DE_72h-GCM2_MA0767.2 8 bp overlap
HIC2 2 datasets
Motif DE_36h DE_36h-HIC2_MA0738.2 6 bp overlap
Motif DE_72h DE_72h-HIC2_MA0738.2 6 bp overlap
HOXB13 1 dataset
ChIP G-401 GSE65381.HOXB13.G-401 542 bp overlap
Hand1::Tcf3 1 dataset
Motif DE_72h DE_72h-Hand1Tcf3_MA0092.2 9 bp overlap
INSM1 2 datasets
Motif DE_24h DE_24h-INSM1_MA0155.1 12 bp overlap
Motif DE_48h DE_48h-INSM1_MA0155.1 12 bp overlap
INTS11 1 dataset
ChIP HeLa GSE125534.INTS11.HeLa 224 bp overlap
Isl1 2 datasets
Motif DE_36h DE_36h-Isl1_MA1608.2 7 bp overlap
Motif DE_72h DE_72h-Isl1_MA1608.2 7 bp overlap
JUN 4 datasets
ChIP DE_D1 S13-DE-d1-JUN-exp1 315 bp overlap
ChIP DE_D1 S40-DE-d1-JUN-exp2 536 bp overlap
ChIP DE_D2 S02-DE-d2-JUN-exp1 589 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 558 bp overlap
KMT2A 3 datasets
ChIP HEK293T_N-term GSE90762.KMT2A.HEK293T_N-term 292 bp overlap
ChIP HEK293T_N-term_C49 GSE90762.KMT2A.HEK293T_N-term_C49 386 bp overlap
ChIP HEK293T_N-term_shCtrl_TASP1-KO GSE90762.KMT2A.HEK293T_N-term_shCtrl_TASP1-KO 305 bp overlap
L3MBTL2 2 datasets
ChIP HEK293T ENCFF482NJV 506 bp overlap
ChIP HEK293T ENCFF482NJV 541 bp overlap
MAFF 2 datasets
Motif DE_36h DE_36h-MAFF_MA0495.4 11 bp overlap
Motif DE_72h DE_72h-MAFF_MA0495.4 11 bp overlap
MED1 1 dataset
ChIP HCT-116_shLuc_thaps GSE121798.MED1.HCT-116_shLuc_thaps 365 bp overlap
MED26 1 dataset
ChIP HEK293T GSE121024.MED26.HEK293T 190 bp overlap
MEIS1 2 datasets
Motif DE_36h DE_36h-MEIS1_MA0498.3 5 bp overlap
Motif DE_72h DE_72h-MEIS1_MA0498.3 5 bp overlap
MXI1 2 datasets
Motif DE_36h DE_36h-MXI1_MA1108.3 6 bp overlap
Motif DE_72h DE_72h-MXI1_MA1108.3 6 bp overlap
MYCN 4 datasets
ChIP CHP-134 GSE129588.MYCN.CHP-134 308 bp overlap
ChIP Kelly GSE94822.MYCN.Kelly 338 bp overlap
ChIP Kelly GSE94782.MYCN.Kelly 144 bp overlap
ChIP LA-N-5 GSE138295.MYCN.LA-N-5 338 bp overlap
Mafb 2 datasets
Motif DE_36h DE_36h-Mafb_MA0117.3 11 bp overlap
Motif DE_72h DE_72h-Mafb_MA0117.3 11 bp overlap
NANOG 1 dataset
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 233 bp overlap
NFATC3 1 dataset
Motif DE_72h DE_72h-NFATC3_MA0625.3 6 bp overlap
NR3C1 1 dataset
ChIP breast_tumor_Male_15 GSE104399.NR3C1.breast_tumor_Male_15 259 bp overlap
NRL 2 datasets
Motif DE_36h DE_36h-NRL_MA0842.3 12 bp overlap
Motif DE_72h DE_72h-NRL_MA0842.3 12 bp overlap
Nfat5 1 dataset
Motif DE_72h DE_72h-Nfat5_MA0606.3 8 bp overlap
Nfatc1 1 dataset
Motif DE_72h DE_72h-Nfatc1_MA0624.3 6 bp overlap
Nr2e3 3 datasets
Motif DE_24h DE_24h-Nr2e3_MA0164.2 6 bp overlap
Motif DE_48h DE_48h-Nr2e3_MA0164.2 6 bp overlap
Motif DE_72h DE_72h-Nr2e3_MA0164.2 6 bp overlap
PHIP 1 dataset
ChIP HEK293_ab833 GSE101646.PHIP.HEK293_ab833 248 bp overlap
POLR2A 2 datasets
ChIP neural cell ENCFF604SPB 385 bp overlap
ChIP spleen ENCFF706IUS 545 bp overlap
POU5F1 2 datasets
ChIP BG03 GSE21614.POU5F1.BG03 153 bp overlap
ChIP DE_D1 DED1-OCT4_Batch_II 651 bp overlap
POU5F1_M 1 dataset
ChIP DE_D1 DED1-OCT4-M_Batch_II 537 bp overlap
PRDM1 1 dataset
ChIP HEK293 ENCFF302TBP 421 bp overlap
PRDM10 1 dataset
ChIP HEK293 ENCFF145WQQ 355 bp overlap
PTBP1 1 dataset
ChIP Hep-G2 ENCSR156APP.PTBP1.Hep-G2 202 bp overlap
RARA 1 dataset
ChIP hiPSC_D2 GSE132532.RARA.hiPSC_D2 214 bp overlap
RELA 1 dataset
ChIP 786-O GSE86092.RELA.786-O 213 bp overlap
RORB 2 datasets
Motif DE_36h DE_36h-RORB_MA1150.2 10 bp overlap
Motif DE_72h DE_72h-RORB_MA1150.2 10 bp overlap
SMAD2 2 datasets
Motif DE_72h DE_72h-SMAD2_MA1964.2 6 bp overlap
ChIP endoderm GSE29422.SMAD2.endoderm 169 bp overlap
SMAD2-3 5 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 793 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 971 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 674 bp overlap
ChIP HUVEC-C_TGFB1 GSE134556.SMAD2-3.HUVEC-C_TGFB1 191 bp overlap
ChIP HUVEC-C_TGFB1 GSE134556.SMAD2-3.HUVEC-C_TGFB1 182 bp overlap
SMAD2_3 5 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 414 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 659 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 782 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 916 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 902 bp overlap
SMAD4 1 dataset
ChIP endoderm GSE29422.SMAD4.endoderm 226 bp overlap
SMARCA4 2 datasets
ChIP G-401_Dox GSE71504.SMARCA4.G-401_Dox 362 bp overlap
ChIP hiPSC GSE124903.SMARCA4.hiPSC 507 bp overlap
SMARCB1 1 dataset
ChIP hiPSC GSE124903.SMARCB1.hiPSC 300 bp overlap
SMARCC1 3 datasets
ChIP DE_D1 S15-DE-d1-BAF155-exp1 518 bp overlap
ChIP G-401_Dox GSE71504.SMARCC1.G-401_Dox 434 bp overlap
ChIP G-401_NoDox GSE71504.SMARCC1.G-401_NoDox 404 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 367 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 690 bp overlap
SP5 9 datasets
Motif DE_24h DE_24h-SP5_MA1965.2 6 bp overlap
Motif DE_24h DE_24h-SP5_MA1965.2 6 bp overlap
Motif DE_36h DE_36h-SP5_MA1965.2 6 bp overlap
Motif DE_36h DE_36h-SP5_MA1965.2 6 bp overlap
Motif DE_48h DE_48h-SP5_MA1965.2 6 bp overlap
Motif DE_48h DE_48h-SP5_MA1965.2 6 bp overlap
Motif DE_72h DE_72h-SP5_MA1965.2 6 bp overlap
Motif DE_72h DE_72h-SP5_MA1965.2 6 bp overlap
Motif DE_72h DE_72h-SP5_MA1965.2 6 bp overlap
SPI1 1 dataset
ChIP macrophage_IFNG GSE47188.SPI1.macrophage_IFNG 324 bp overlap
T 2 datasets
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 260 bp overlap
ChIP H9_MESODERM GSE60606.T.H9_MESODERM 184 bp overlap
TAL1 1 dataset
ChIP K-562_enCRISPRi-LK GSE132212.TAL1.K-562_enCRISPRi-LK 142 bp overlap
TAL1::TCF3 2 datasets
Motif DE_36h DE_36h-TAL1TCF3_MA0091.2 10 bp overlap
Motif DE_72h DE_72h-TAL1TCF3_MA0091.2 10 bp overlap
TBL1X 1 dataset
ChIP HEK293T GSE35197.TBL1X.HEK293T 255 bp overlap
TBP 1 dataset
ChIP K-562 GSE55306.TBP.K-562 177 bp overlap
TEAD4 1 dataset
ChIP MCF-7_BLRP_WT_E2 GSE125594.TEAD4.MCF-7_BLRP_WT_E2 230 bp overlap
TFAP2A 6 datasets
Motif DE_24h DE_24h-TFAP2A_MA0872.1 13 bp overlap
Motif DE_36h DE_36h-TFAP2A_MA0872.1 13 bp overlap
Motif DE_48h DE_48h-TFAP2A_MA0872.1 13 bp overlap
Motif DE_72h DE_72h-TFAP2A_MA0872.1 13 bp overlap
ChIP WA09 GSE105081.TFAP2A.WA09 242 bp overlap
ChIP WA09 GSE105081.TFAP2A.WA09 70 bp overlap
TFAP2B 5 datasets
Motif DE_24h DE_24h-TFAP2B_MA0813.1 13 bp overlap
Motif DE_36h DE_36h-TFAP2B_MA0813.1 13 bp overlap
Motif DE_48h DE_48h-TFAP2B_MA0813.1 13 bp overlap
Motif DE_72h DE_72h-TFAP2B_MA0813.1 13 bp overlap
ChIP SK-N-SH ENCFF869XXQ 441 bp overlap
TFAP2C 5 datasets
Motif DE_24h DE_24h-TFAP2C_MA0815.1 13 bp overlap
Motif DE_36h DE_36h-TFAP2C_MA0815.1 13 bp overlap
Motif DE_48h DE_48h-TFAP2C_MA0815.1 13 bp overlap
Motif DE_72h DE_72h-TFAP2C_MA0815.1 13 bp overlap
ChIP WA09 GSE105081.TFAP2C.WA09 197 bp overlap
TP63 1 dataset
ChIP foreskin GSE126390.TP63.foreskin 154 bp overlap
YY1 2 datasets
ChIP Hep-G2_NC GSE120104.YY1.Hep-G2_NC 344 bp overlap
ChIP Hep-G2_RBM25-KD GSE120104.YY1.Hep-G2_RBM25-KD 422 bp overlap
ZBTB33 2 datasets
ChIP K-562 ENCSR876GXA.ZBTB33.K-562 513 bp overlap
ChIP K562 ENCFF875HLX 336 bp overlap
ZBTB42 1 dataset
ChIP HEK293 GSE76494.ZBTB42.HEK293 224 bp overlap
ZBTB7C 2 datasets
Motif DE_36h DE_36h-ZBTB7C_MA0695.2 8 bp overlap
Motif DE_72h DE_72h-ZBTB7C_MA0695.2 8 bp overlap
ZEB1 2 datasets
Motif DE_36h DE_36h-ZEB1_MA0103.4 6 bp overlap
Motif DE_72h DE_72h-ZEB1_MA0103.4 6 bp overlap
ZFP14 4 datasets
Motif DE_24h DE_24h-ZFP14_MA1972.1 15 bp overlap
Motif DE_36h DE_36h-ZFP14_MA1972.1 15 bp overlap
Motif DE_48h DE_48h-ZFP14_MA1972.1 15 bp overlap
Motif DE_72h DE_72h-ZFP14_MA1972.1 15 bp overlap
ZFX 1 dataset
ChIP HEK293T_FLAG GSE145160.ZFX.HEK293T_FLAG 393 bp overlap
ZIC1 2 datasets
Motif DE_36h DE_36h-ZIC1_MA0696.1 14 bp overlap
Motif DE_72h DE_72h-ZIC1_MA0696.1 14 bp overlap
ZIC2 1 dataset
ChIP HEK293 ENCFF033NQQ 601 bp overlap
ZIC4 2 datasets
Motif DE_36h DE_36h-ZIC4_MA0751.2 14 bp overlap
Motif DE_72h DE_72h-ZIC4_MA0751.2 14 bp overlap
ZIC5 2 datasets
Motif DE_36h DE_36h-ZIC5_MA1584.2 15 bp overlap
Motif DE_72h DE_72h-ZIC5_MA1584.2 15 bp overlap
ZKSCAN3 1 dataset
Motif DE_72h DE_72h-ZKSCAN3_MA1973.2 14 bp overlap
ZNF273 1 dataset
ChIP HEK293T GSE78099.ZNF273.HEK293T 196 bp overlap
ZNF320 1 dataset
ChIP HEK293 GSE76494.ZNF320.HEK293 157 bp overlap
ZNF341 3 datasets
ChIP HEK293 ENCFF944VMC 291 bp overlap
ChIP HEK293 ENCSR185FOY.ZNF341.HEK293 438 bp overlap
ChIP HEK293 GSE76494.ZNF341.HEK293 239 bp overlap
ZNF454 2 datasets
Motif DE_24h DE_24h-ZNF454_MA1712.2 17 bp overlap
Motif DE_48h DE_48h-ZNF454_MA1712.2 17 bp overlap
ZNF667 3 datasets
Motif DE_24h DE_24h-ZNF667_MA1984.2 11 bp overlap
Motif DE_36h DE_36h-ZNF667_MA1984.2 11 bp overlap
Motif DE_72h DE_72h-ZNF667_MA1984.2 11 bp overlap
ZNF677 1 dataset
ChIP HEK293 ENCSR279KDC.ZNF677.HEK293 202 bp overlap
ZNF680 1 dataset
Motif DE_72h DE_72h-ZNF680_MA1729.2 11 bp overlap
ZNF684 4 datasets
Motif DE_24h DE_24h-ZNF684_MA1600.2 14 bp overlap
Motif DE_36h DE_36h-ZNF684_MA1600.2 14 bp overlap
Motif DE_48h DE_48h-ZNF684_MA1600.2 14 bp overlap
Motif DE_72h DE_72h-ZNF684_MA1600.2 14 bp overlap
ZNF737 1 dataset
ChIP Hep-G2 ENCSR127IHN.ZNF737.Hep-G2 199 bp overlap
Zfx 2 datasets
Motif DE_24h DE_24h-Zfx_MA0146.3 10 bp overlap
Motif DE_48h DE_48h-Zfx_MA0146.3 10 bp overlap
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