chr12 : 89,374,559 – 89,374,925

366 bp 94 TFs 1 linked gene

This 366 bp open chromatin element is linked to ENSG00000271327 and is bound by 94 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000271327		6.8 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

94 transcription factors

ARID1A 1 dataset

ChIP 12Z GSE129781.ARID1A.12Z 82 bp overlap

Ahr::Arnt 1 dataset

Motif DE_36h DE_36h-AhrArnt_MA0006.2 5 bp overlap

BRD4 14 datasets

ChIP COLO-205 GSE73319.BRD4.COLO-205 63 bp overlap

ChIP HCC1806_DMSO_24h GSE87418.BRD4.HCC1806_DMSO_24h 75 bp overlap

ChIP HUVEC-C_TNF GSE53998.BRD4.HUVEC-C_TNF 125 bp overlap

ChIP MDA-MB-231_DMSO GSE116879.BRD4.MDA-MB-231_DMSO 203 bp overlap

ChIP MDA-MB-231_DMSO_rDNA GSE116879.BRD4.MDA-MB-231_DMSO_rDNA 199 bp overlap

ChIP MDA-MB-231_JQ1-neg_S_3f GSE136151.BRD4.MDA-MB-231_JQ1-neg_S_3f 256 bp overlap

ChIP PC-3_GDC-R GSE137207.BRD4.PC-3_GDC-R 236 bp overlap

ChIP PC-3_GDC-R_SAHA GSE137207.BRD4.PC-3_GDC-R_SAHA 358 bp overlap

ChIP SUM159PT_DMSO_48h GSE87418.BRD4.SUM159PT_DMSO_48h 148 bp overlap

ChIP SUM159PT_DMSO_72h GSE87418.BRD4.SUM159PT_DMSO_72h 50 bp overlap

ChIP SUM159PT_Dox_48h GSE87418.BRD4.SUM159PT_Dox_48h 118 bp overlap

ChIP SUM159PT_shMYC_DMSO_48h GSE87418.BRD4.SUM159PT_shMYC_DMSO_48h 100 bp overlap

ChIP SUM229PE_pos_DMSO_24h GSE87418.BRD4.SUM229PE_pos_DMSO_24h 73 bp overlap

ChIP SW480 GSE73319.BRD4.SW480 104 bp overlap

BRD9 1 dataset

ChIP Mel270_DMSO GSE124720.BRD9.Mel270_DMSO 199 bp overlap

CDK8 1 dataset

ChIP SW480 GSE53602.CDK8.SW480 85 bp overlap

CDKN1B 1 dataset

ChIP MDA-MB-231_p27CK-DD GSE112444.CDKN1B.MDA-MB-231_p27CK-DD 182 bp overlap

CEBPB 1 dataset

ChIP HFOB_DIFF GSE82295.CEBPB.HFOB_DIFF 118 bp overlap

Crx 1 dataset

Motif DE_36h DE_36h-Crx_MA0467.3 6 bp overlap

EHF 1 dataset

ChIP RWPE-1 GSE114241.EHF.RWPE-1 92 bp overlap

ELF3 3 datasets

ChIP PDAC GSE64557.ELF3.PDAC 145 bp overlap

ChIP PDAC_KOKLF5 GSE64557.ELF3.PDAC_KOKLF5 181 bp overlap

ChIP PDAC_SHCTR GSE64557.ELF3.PDAC_SHCTR 154 bp overlap

EOMES 2 datasets

Motif DE_36h DE_36h-EOMES_MA0800.2 9 bp overlap

ChIP hESC GSE26097.EOMES.hESC 131 bp overlap

EP300 1 dataset

ChIP Ishikawa ENCSR000BUE.EP300.Ishikawa 144 bp overlap

ERG 1 dataset

ChIP RWPE-1 GSE114241.ERG.RWPE-1 100 bp overlap

ESR1 6 datasets

ChIP Ishikawa ENCSR000BIY.ESR1.Ishikawa 97 bp overlap

ChIP Ishikawa_DMSO_D538G_clone3 GSE132426.ESR1.Ishikawa_DMSO_D538G_clone3 206 bp overlap

ChIP Ishikawa_E2_D538G GSE132426.ESR1.Ishikawa_E2_D538G 366 bp overlap

ChIP Ishikawa_M1-9-1 GSE147141.ESR1.Ishikawa_M1-9-1 144 bp overlap

ChIP endometrioid-adenocarcinoma_tumor_3 GSE94031.ESR1.endometrioid-adenocarcinoma_tumor_3 70 bp overlap

ChIP primary-endometrium-cancer_E1_DSG GSE114737.ESR1.primary-endometrium-cancer_E1_DSG 102 bp overlap

FEZF1 1 dataset

ChIP HEK293 ENCSR827NWO.FEZF1.HEK293 73 bp overlap

FEZF2 1 dataset

Motif DE_36h DE_36h-FEZF2_MA2341.1 8 bp overlap

FIGLA 1 dataset

Motif DE_36h DE_36h-FIGLA_MA0820.2 6 bp overlap

FOSL2 1 dataset

Motif DE_36h DE_36h-FOSL2_MA0478.2 10 bp overlap

FOXA1 3 datasets

ChIP PDAC GSE64557.FOXA1.PDAC 118 bp overlap

ChIP PDAC_KOKLF5 GSE64557.FOXA1.PDAC_KOKLF5 150 bp overlap

ChIP PDAC_SHCTR GSE64557.FOXA1.PDAC_SHCTR 164 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 274 bp overlap

ChIP DE DE-FOXA2-2 236 bp overlap

FOXL2 1 dataset

ChIP HGrC1_C134W-TGF_parental GSE138496.FOXL2.HGrC1_C134W-TGF_parental 60 bp overlap

FOXM1 1 dataset

ChIP Ishikawa ENCSR000BUS.FOXM1.Ishikawa 77 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 325 bp overlap

ChIP DE DE-GATA4-2 366 bp overlap

GATA6 5 datasets

ChIP DE DE-GATA6-1 314 bp overlap

ChIP DE DE-GATA6-2 364 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 344 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 192 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 222 bp overlap

GLIS1 1 dataset

ChIP HEK293 ENCFF299RSE 61 bp overlap

GSC 1 dataset

Motif DE_36h DE_36h-GSC_MA0648.2 6 bp overlap

GSC2 1 dataset

Motif DE_36h DE_36h-GSC2_MA0891.2 6 bp overlap

GTF2E2 1 dataset

ChIP K562 ENCFF741URT 153 bp overlap

HES1 1 dataset

Motif DE_36h DE_36h-HES1_MA1099.3 8 bp overlap

HNF1B 1 dataset

ChIP PDAC GSE64557.HNF1B.PDAC 99 bp overlap

HOXB8 1 dataset

ChIP CFPAC-1_HOXB8-OE GSE119930.HOXB8.CFPAC-1_HOXB8-OE 51 bp overlap

IRF1 1 dataset

ChIP PDAC GSE64557.IRF1.PDAC 165 bp overlap

JUN 1 dataset

ChIP HeLa-S3 ENCFF668QVP 157 bp overlap

KLF4 1 dataset

ChIP PDAC GSE64557.KLF4.PDAC 91 bp overlap

KLF6 1 dataset

ChIP PDAC GSE64557.KLF6.PDAC 265 bp overlap

MED1 1 dataset

ChIP U-87MG GSE36354.MED1.U-87MG 122 bp overlap

MGA 1 dataset

Motif DE_36h DE_36h-MGA_MA0801.1 8 bp overlap

MRTFB 1 dataset

ChIP A-673-clone-Asp114 GSE92738.MRTFB.A-673-clone-Asp114 55 bp overlap

MYBL2 1 dataset

ChIP A-673 GSE119971.MYBL2.A-673 92 bp overlap

NFIC 1 dataset

ChIP Ishikawa ENCSR000BUT.NFIC.Ishikawa 153 bp overlap

NR3C1 4 datasets

ChIP BEAS-2B_DEX_IA1 GSE125623.NR3C1.BEAS-2B_DEX_IA1 56 bp overlap

ChIP BEAS-2B_TNF-DEX_IA1 GSE125623.NR3C1.BEAS-2B_TNF-DEX_IA1 99 bp overlap

ChIP BEAS-2B_TNF_IA1 GSE125623.NR3C1.BEAS-2B_TNF_IA1 130 bp overlap

ChIP BEAS-2B_Veh_IA1 GSE125623.NR3C1.BEAS-2B_Veh_IA1 93 bp overlap

OTX1 1 dataset

Motif DE_36h DE_36h-OTX1_MA0711.2 6 bp overlap

PHIP 4 datasets

ChIP HCT-116_MLL1-KO__ab833 GSE101646.PHIP.HCT-116_MLL1-KO__ab833 329 bp overlap

ChIP HCT-116_ab833 GSE101646.PHIP.HCT-116_ab833 222 bp overlap

ChIP HCT-116_ab834 GSE101646.PHIP.HCT-116_ab834 366 bp overlap

ChIP HEK293_ab833 GSE101646.PHIP.HEK293_ab833 111 bp overlap

PITX1 1 dataset

Motif DE_36h DE_36h-PITX1_MA0682.3 6 bp overlap

PITX3 1 dataset

Motif DE_36h DE_36h-PITX3_MA0714.2 6 bp overlap

PKNOX2 1 dataset

Motif DE_36h DE_36h-PKNOX2_MA0783.1 12 bp overlap

PRDM6 1 dataset

ChIP HEK293 ENCSR892QHR.PRDM6.HEK293 105 bp overlap

Ptf1A 1 dataset

Motif DE_36h DE_36h-Ptf1A_MA1620.2 8 bp overlap

RELA 3 datasets

ChIP FaDu_LPS GSE132018.RELA.FaDu_LPS 73 bp overlap

ChIP SGBS_TNF GSE64233.RELA.SGBS_TNF 89 bp overlap

ChIP aortic-endothelial-cell_IL1B_D35 GSE139377.RELA.aortic-endothelial-cell_IL1B_D35 60 bp overlap

RHOXF1 1 dataset

Motif DE_36h DE_36h-RHOXF1_MA0719.2 6 bp overlap

SAP130 1 dataset

ChIP HepG2 ENCFF892EHZ 64 bp overlap

SCRT1 1 dataset

ChIP HEK293 ENCSR605MGM.SCRT1.HEK293 87 bp overlap

SMAD2 1 dataset

ChIP endoderm GSE29422.SMAD2.endoderm 151 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 358 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 237 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 344 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 304 bp overlap

SMAD4 1 dataset

ChIP endoderm GSE29422.SMAD4.endoderm 137 bp overlap

SMARCA2 2 datasets

ChIP NPC_AM GSE122631.SMARCA2.NPC_AM 120 bp overlap

ChIP NPC_K755R-siCT GSE122631.SMARCA2.NPC_K755R-siCT 68 bp overlap

SMARCA4 1 dataset

ChIP NPC_K755R-siCT GSE122631.SMARCA4.NPC_K755R-siCT 60 bp overlap

SMARCC1 1 dataset

ChIP Aska-SS_shSSX GSE108025.SMARCC1.Aska-SS_shSSX 87 bp overlap

SNAI2 1 dataset

Motif DE_36h DE_36h-SNAI2_MA0745.3 8 bp overlap

SNAI3 1 dataset

Motif DE_36h DE_36h-SNAI3_MA1559.2 9 bp overlap

SP5 1 dataset

Motif DE_36h DE_36h-SP5_MA1965.2 6 bp overlap

SREBP2 1 dataset

ChIP monocyte_TNF GSE129202.SREBP2.monocyte_TNF 119 bp overlap

SS18 1 dataset

ChIP SYO-1 GSE108025.SS18.SYO-1 60 bp overlap

SUPT5H 1 dataset

ChIP DLD-1_NELFCD-AID_treated GSE144786.SUPT5H.DLD-1_NELFCD-AID_treated 116 bp overlap

TBR1 1 dataset

Motif DE_36h DE_36h-TBR1_MA0802.2 9 bp overlap

TBX1 1 dataset

Motif DE_36h DE_36h-TBX1_MA0805.1 8 bp overlap

TBX15 1 dataset

Motif DE_36h DE_36h-TBX15_MA0803.1 8 bp overlap

TBX18 1 dataset

Motif DE_36h DE_36h-TBX18_MA1565.2 9 bp overlap

TBX2 1 dataset

Motif DE_36h DE_36h-TBX2_MA0688.2 9 bp overlap

TBX21 1 dataset

Motif DE_36h DE_36h-TBX21_MA0690.3 10 bp overlap

TBX3 1 dataset

Motif DE_36h DE_36h-TBX3_MA1566.3 9 bp overlap

TBX4 1 dataset

Motif DE_36h DE_36h-TBX4_MA0806.1 8 bp overlap

TBX5 1 dataset

Motif DE_36h DE_36h-TBX5_MA0807.1 8 bp overlap

TCF12 2 datasets

ChIP Ishikawa ENCFF467DDW 60 bp overlap

ChIP Ishikawa ENCSR000BUV.TCF12.Ishikawa 153 bp overlap

TFAP2C 1 dataset

Motif DE_36h DE_36h-TFAP2C_MA0814.3 9 bp overlap

TGIF1 1 dataset

Motif DE_36h DE_36h-TGIF1_MA0796.1 12 bp overlap

TGIF2 1 dataset

Motif DE_36h DE_36h-TGIF2_MA0797.1 12 bp overlap

Tbx6 1 dataset

Motif DE_36h DE_36h-Tbx6_MA1567.3 9 bp overlap

UBN1 1 dataset

ChIP HeLa GSE45024.UBN1.HeLa 71 bp overlap

Wt1 1 dataset

Motif DE_36h DE_36h-Wt1_MA1627.2 10 bp overlap

YY1 1 dataset

ChIP liver ENCFF400MBC 168 bp overlap

ZBTB18 1 dataset

Motif DE_36h DE_36h-ZBTB18_MA0698.2 11 bp overlap

ZEB1 1 dataset

Motif DE_36h DE_36h-ZEB1_MA0103.4 6 bp overlap

ZEB2 1 dataset

ChIP HEK293 ENCSR417VWF.ZEB2.HEK293 85 bp overlap

ZNF135 1 dataset

Motif DE_36h DE_36h-ZNF135_MA1587.1 14 bp overlap

ZNF143 1 dataset

Motif DE_36h DE_36h-ZNF143_MA0088.2 16 bp overlap

ZNF2 1 dataset

ChIP HEK293 ENCSR011CKE.ZNF2.HEK293 58 bp overlap

ZNF460 1 dataset

Motif DE_36h DE_36h-ZNF460_MA1596.1 16 bp overlap

ZNF629 1 dataset

ChIP HEK293 ENCSR351NON.ZNF629.HEK293 153 bp overlap

ZNF76 1 dataset

Motif DE_36h DE_36h-ZNF76_MA1716.2 17 bp overlap

ZNF770 1 dataset

Motif DE_36h DE_36h-ZNF770_MA2099.1 8 bp overlap

ZSCAN21 1 dataset

Motif DE_36h DE_36h-ZSCAN21_MA2336.1 7 bp overlap

ZXDB 1 dataset

ChIP HEK293 ENCFF835SGA 78 bp overlap