chr8 : 135,731,713 – 135,732,833
1,120 bp 95 TFs 1 linked gene
This 1.1 kb open chromatin element is linked to KHDRBS3 and is bound by 95 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
KHDRBS3 274.9 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr8:135,726,713 – 135,737,833
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
95 transcription factors
Source
Cell type
BHLHE22 1 dataset
Motif DE_72h DE_72h-BHLHE22_MA1635.2 6 bp overlap
CREB1 1 dataset
Motif DE_72h DE_72h-CREB1_MA0018.5 8 bp overlap
CTCF 3 datasets
ChIP OCI-Ly3 ENCSR756ZKG.CTCF.OCI-Ly3 356 bp overlap
ChIP endodermal cell ENCFF471YCZ 461 bp overlap
ChIP hESC_D5 GSE116862.CTCF.hESC_D5 288 bp overlap
CTCFL 1 dataset
ChIP Kelly_shLUC-res GSE115248.CTCFL.Kelly_shLUC-res 144 bp overlap
Cebpa 1 dataset
ChIP BLaER1 ENCFF262VBH 277 bp overlap
E2F2 1 dataset
Motif DE_72h DE_72h-E2F2_MA0864.3 13 bp overlap
E2F6 2 datasets
ChIP K-562 ENCSR000BLI.E2F6.K-562 99 bp overlap
ChIP WA01 ENCSR000BSI.E2F6.WA01 179 bp overlap
E2F7 1 dataset
Motif DE_72h DE_72h-E2F7_MA0758.1 14 bp overlap
EOMES 2 datasets
Motif DE_72h DE_72h-EOMES_MA0800.2 9 bp overlap
ChIP hESC GSE26097.EOMES.hESC 182 bp overlap
ERF::FIGLA 2 datasets
Motif DE_60h DE_60h-ERFFIGLA_MA1934.2 13 bp overlap
Motif DE_72h DE_72h-ERFFIGLA_MA1934.2 13 bp overlap
ETV2::FIGLA 2 datasets
Motif DE_60h DE_60h-ETV2FIGLA_MA1941.2 13 bp overlap
Motif DE_72h DE_72h-ETV2FIGLA_MA1941.2 13 bp overlap
ETV5::FIGLA 2 datasets
Motif DE_60h DE_60h-ETV5FIGLA_MA1945.2 14 bp overlap
Motif DE_72h DE_72h-ETV5FIGLA_MA1945.2 14 bp overlap
EWSR1-FLI1 1 dataset
Motif DE_72h DE_72h-EWSR1-FLI1_MA0149.1 18 bp overlap
EZH2 5 datasets
ChIP A-1847 GSE95643.EZH2.A-1847 160 bp overlap
ChIP PC-9 ENCSR793USK.EZH2.PC-9 821 bp overlap
ChIP SK-N-MC ENCFF434OHW 382 bp overlap
ChIP SK-N-MC ENCFF674XUJ 433 bp overlap
ChIP T98G GSE112240.EZH2.T98G 461 bp overlap
FEZF2 2 datasets
Motif DE_60h DE_60h-FEZF2_MA2341.1 8 bp overlap
Motif DE_72h DE_72h-FEZF2_MA2341.1 8 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 600 bp overlap
ChIP DE DE-FOXA2-2 471 bp overlap
FOXP2 1 dataset
Motif DE_72h DE_72h-FOXP2_MA0593.2 9 bp overlap
GATA2 2 datasets
ChIP CD34_DMSO GSE60792.GATA2.CD34_DMSO 146 bp overlap
ChIP hiPSC_SLC6ebs GSE107639.GATA2.hiPSC_SLC6ebs 182 bp overlap
GATA4 5 datasets
ChIP DE DE-GATA4-1 810 bp overlap
ChIP DE DE-GATA4-2 1030 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap
ChIP foregut GSE117136.GATA4.foregut 431 bp overlap
GATA5 2 datasets
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
Motif DE_72h DE_72h-GATA5_MA0766.3 8 bp overlap
GATA6 10 datasets
ChIP DE DE-GATA6-1 727 bp overlap
ChIP DE DE-GATA6-2 1018 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 305 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 832 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 468 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 259 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 737 bp overlap
ChIP foregut GSE117136.GATA6.foregut 484 bp overlap
Gata3 2 datasets
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap
HNRNPH1 2 datasets
ChIP Hep-G2 GSE120104.HNRNPH1.Hep-G2 71 bp overlap
ChIP Hep-G2 ENCSR066FXN.HNRNPH1.Hep-G2 74 bp overlap
IKZF2 2 datasets
Motif DE_60h DE_60h-IKZF2_MA2326.1 6 bp overlap
Motif DE_72h DE_72h-IKZF2_MA2326.1 6 bp overlap
JUN 1 dataset
ChIP MDA-MB-231 GSE112444.JUN.MDA-MB-231 219 bp overlap
KLF4 2 datasets
ChIP BJ_INDUCED GSE36570.KLF4.BJ_INDUCED 261 bp overlap
ChIP BJ_INDUCED GSE36570.KLF4.BJ_INDUCED 112 bp overlap
KLF9 1 dataset
ChIP GBM1A GSE62211.KLF9.GBM1A 86 bp overlap
MAFK 2 datasets
ChIP Hep-G2 ENCSR000EDZ.MAFK.Hep-G2 164 bp overlap
ChIP HepG2 ENCFF743ZOF 241 bp overlap
MEIS1 2 datasets
Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap
Motif DE_72h DE_72h-MEIS1_MA0498.3 5 bp overlap
MGA 1 dataset
Motif DE_72h DE_72h-MGA_MA0801.1 8 bp overlap
MYF6 2 datasets
Motif DE_60h DE_60h-MYF6_MA0667.1 10 bp overlap
Motif DE_72h DE_72h-MYF6_MA0667.1 10 bp overlap
Mecom 2 datasets
Motif DE_60h DE_60h-Mecom_MA0029.2 11 bp overlap
Motif DE_72h DE_72h-Mecom_MA0029.2 11 bp overlap
NHLH1 1 dataset
Motif DE_72h DE_72h-NHLH1_MA0048.3 9 bp overlap
Neurod2 1 dataset
Motif DE_72h DE_72h-Neurod2_MA1993.2 6 bp overlap
Olig2 1 dataset
Motif DE_72h DE_72h-Olig2_MA1997.2 6 bp overlap
PATZ1 1 dataset
Motif DE_72h DE_72h-PATZ1_MA1961.2 11 bp overlap
PKNOX2 2 datasets
Motif DE_60h DE_60h-PKNOX2_MA0783.1 12 bp overlap
Motif DE_72h DE_72h-PKNOX2_MA0783.1 12 bp overlap
POU2F1::SOX2 2 datasets
Motif DE_60h DE_60h-POU2F1SOX2_MA1962.1 17 bp overlap
Motif DE_72h DE_72h-POU2F1SOX2_MA1962.1 17 bp overlap
POU5F1 1 dataset
ChIP BJ_INDUCED GSE36570.POU5F1.BJ_INDUCED 127 bp overlap
PRDM1 2 datasets
Motif DE_60h DE_60h-PRDM1_MA0508.4 7 bp overlap
Motif DE_72h DE_72h-PRDM1_MA0508.4 7 bp overlap
PRDM9 2 datasets
Motif DE_60h DE_60h-PRDM9_MA1723.2 20 bp overlap
Motif DE_72h DE_72h-PRDM9_MA1723.2 20 bp overlap
Ptf1A 1 dataset
Motif DE_72h DE_72h-Ptf1A_MA1619.2 8 bp overlap
RAD21 1 dataset
ChIP RH4 GSE83726.RAD21.RH4 169 bp overlap
RELA 1 dataset
ChIP 786-O GSE86092.RELA.786-O 352 bp overlap
RREB1 1 dataset
Motif DE_72h DE_72h-RREB1_MA0073.2 19 bp overlap
RUNX1T1 1 dataset
ChIP Kasumi-1_E2 GSE102697.RUNX1T1.Kasumi-1_E2 256 bp overlap
SMAD2 2 datasets
ChIP endoderm GSE29422.SMAD2.endoderm 133 bp overlap
ChIP endoderm GSE29422.SMAD2.endoderm 297 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 920 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 653 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 273 bp overlap
SMAD2_3 3 datasets
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 330 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 701 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 712 bp overlap
SMAD4 1 dataset
ChIP endoderm GSE29422.SMAD4.endoderm 226 bp overlap
SOX10 2 datasets
Motif DE_60h DE_60h-SOX10_MA0442.3 6 bp overlap
Motif DE_72h DE_72h-SOX10_MA0442.3 6 bp overlap
SP5 2 datasets
Motif DE_72h DE_72h-SP5_MA1965.2 6 bp overlap
Motif DE_72h DE_72h-SP5_MA1965.2 6 bp overlap
SS18-SSX 2 datasets
ChIP fibroblast_78aa-SSX-Tail GSE139053.SS18-SSX.fibroblast_78aa-SSX-Tail 199 bp overlap
ChIP fibroblast_78aa-SSX-Tail GSE139053.SS18-SSX.fibroblast_78aa-SSX-Tail 303 bp overlap
SUZ12 2 datasets
ChIP Aska-SS GSE108025.SUZ12.Aska-SS 364 bp overlap
ChIP Aska-SS GSE108025.SUZ12.Aska-SS 457 bp overlap
Stat2 2 datasets
Motif DE_60h DE_60h-Stat2_MA1623.2 10 bp overlap
Motif DE_72h DE_72h-Stat2_MA1623.2 10 bp overlap
TBR1 1 dataset
Motif DE_72h DE_72h-TBR1_MA0802.2 9 bp overlap
TBX1 1 dataset
Motif DE_72h DE_72h-TBX1_MA0805.1 8 bp overlap
TBX15 1 dataset
Motif DE_72h DE_72h-TBX15_MA0803.1 8 bp overlap
TBX18 1 dataset
Motif DE_72h DE_72h-TBX18_MA1565.2 9 bp overlap
TBX2 1 dataset
Motif DE_72h DE_72h-TBX2_MA0688.2 9 bp overlap
TBX20 1 dataset
Motif DE_72h DE_72h-TBX20_MA0689.1 11 bp overlap
TBX21 1 dataset
Motif DE_72h DE_72h-TBX21_MA0690.3 10 bp overlap
TBX3 1 dataset
Motif DE_72h DE_72h-TBX3_MA1566.3 9 bp overlap
TBX4 1 dataset
Motif DE_72h DE_72h-TBX4_MA0806.1 8 bp overlap
TBX5 1 dataset
Motif DE_72h DE_72h-TBX5_MA0807.1 8 bp overlap
TEAD4 1 dataset
Motif DE_72h DE_72h-TEAD4_MA0809.3 8 bp overlap
TET2 1 dataset
ChIP Jurkat_NCKD GSE85524.TET2.Jurkat_NCKD 242 bp overlap
TFAP2C 2 datasets
ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 391 bp overlap
ChIP UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc 472 bp overlap
TFAP4 1 dataset
Motif DE_72h DE_72h-TFAP4_MA0691.1 10 bp overlap
TFAP4::ETV1 2 datasets
Motif DE_60h DE_60h-TFAP4ETV1_MA1966.2 13 bp overlap
Motif DE_72h DE_72h-TFAP4ETV1_MA1966.2 13 bp overlap
TFAP4::FLI1 2 datasets
Motif DE_60h DE_60h-TFAP4FLI1_MA1967.2 14 bp overlap
Motif DE_72h DE_72h-TFAP4FLI1_MA1967.2 14 bp overlap
TGIF1 2 datasets
Motif DE_60h DE_60h-TGIF1_MA0796.1 12 bp overlap
Motif DE_72h DE_72h-TGIF1_MA0796.1 12 bp overlap
TGIF2 2 datasets
Motif DE_60h DE_60h-TGIF2_MA0797.1 12 bp overlap
Motif DE_72h DE_72h-TGIF2_MA0797.1 12 bp overlap
TGIF2LX 1 dataset
Motif DE_72h DE_72h-TGIF2LX_MA1571.1 12 bp overlap
TGIF2LY 3 datasets
Motif DE_60h DE_60h-TGIF2LY_MA1572.1 12 bp overlap
Motif DE_72h DE_72h-TGIF2LY_MA1572.1 12 bp overlap
Motif DE_72h DE_72h-TGIF2LY_MA1572.1 12 bp overlap
TRPS1 2 datasets
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap
Tbx6 2 datasets
Motif DE_72h DE_72h-Tbx6_MA1567.3 9 bp overlap
Motif DE_72h DE_72h-Tbx6_MA1567.3 9 bp overlap
Tcf12 1 dataset
Motif DE_72h DE_72h-Tcf12_MA0521.3 6 bp overlap
Twist2 1 dataset
Motif DE_72h DE_72h-Twist2_MA0633.3 6 bp overlap
VEZF1 1 dataset
Motif DE_72h DE_72h-VEZF1_MA1578.2 6 bp overlap
ZNF135 2 datasets
Motif DE_60h DE_60h-ZNF135_MA1587.1 14 bp overlap
Motif DE_72h DE_72h-ZNF135_MA1587.1 14 bp overlap
ZNF148 1 dataset
Motif DE_72h DE_72h-ZNF148_MA1653.2 10 bp overlap
ZNF184 2 datasets
Motif DE_60h DE_60h-ZNF184_MA2120.1 13 bp overlap
Motif DE_72h DE_72h-ZNF184_MA2120.1 13 bp overlap
ZNF257 1 dataset
Motif DE_72h DE_72h-ZNF257_MA1710.2 10 bp overlap
ZNF263 2 datasets
Motif DE_60h DE_60h-ZNF263_MA0528.3 7 bp overlap
Motif DE_72h DE_72h-ZNF263_MA0528.3 7 bp overlap
ZNF281 2 datasets
Motif DE_72h DE_72h-ZNF281_MA1630.3 10 bp overlap
Motif DE_72h DE_72h-ZNF281_MA1630.3 10 bp overlap
ZNF317 1 dataset
Motif DE_72h DE_72h-ZNF317_MA1593.2 8 bp overlap
ZNF449 1 dataset
Motif DE_72h DE_72h-ZNF449_MA1656.2 10 bp overlap
ZNF460 2 datasets
Motif DE_60h DE_60h-ZNF460_MA1596.1 16 bp overlap
Motif DE_72h DE_72h-ZNF460_MA1596.1 16 bp overlap
ZNF530 2 datasets
Motif DE_60h DE_60h-ZNF530_MA1981.2 14 bp overlap
Motif DE_72h DE_72h-ZNF530_MA1981.2 14 bp overlap
ZNF652 1 dataset
Motif DE_72h DE_72h-ZNF652_MA1657.2 9 bp overlap
ZNF684 1 dataset
Motif DE_72h DE_72h-ZNF684_MA1600.2 14 bp overlap
ZNF701 3 datasets
Motif DE_60h DE_60h-ZNF701_MA1987.2 17 bp overlap
Motif DE_72h DE_72h-ZNF701_MA1987.2 17 bp overlap
Motif DE_72h DE_72h-ZNF701_MA1987.2 17 bp overlap
ZNF75A 1 dataset
Motif DE_72h DE_72h-ZNF75A_MA2097.1 12 bp overlap
ZNF770 2 datasets
Motif DE_60h DE_60h-ZNF770_MA2099.1 8 bp overlap
Motif DE_72h DE_72h-ZNF770_MA2099.1 8 bp overlap
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