chr8 : 116,353,345 – 116,353,861

516 bp 89 TFs 0 linked genes

This 516 bp open chromatin element has no linked target genes and is bound by 89 transcription factors.

Linked Genes

No linked genes

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

89 transcription factors

AR 2 datasets

ChIP LNCaP_DHT GSE125245.AR.LNCaP_DHT 85 bp overlap

ChIP MCF-7 GSE48930.AR.MCF-7 164 bp overlap

BACH1 2 datasets

ChIP H1 ENCFF282VDB 321 bp overlap

ChIP WA01 ENCSR000EBQ.BACH1.WA01 224 bp overlap

BRD4 5 datasets

ChIP CD4_Th1_DMSO GSE62482.BRD4.CD4_Th1_DMSO 76 bp overlap

ChIP CD4_Th1_DMSO GSE62482.BRD4.CD4_Th1_DMSO 199 bp overlap

ChIP MCF-7_ARID1A-KO GSE123284.BRD4.MCF-7_ARID1A-KO 322 bp overlap

ChIP MCF-7_ARID1A-KO_4-OHT GSE123284.BRD4.MCF-7_ARID1A-KO_4-OHT 323 bp overlap

ChIP MCF-7_parental_4-hydroxytamoxifen GSE123284.BRD4.MCF-7_parental_4-hydroxytamoxifen 516 bp overlap

Bach1::Mafk 2 datasets

Motif DE_12h DE_12h-Bach1Mafk_MA0591.2 12 bp overlap

Motif ES_0h ES_0h-Bach1Mafk_MA0591.2 12 bp overlap

CHD7 1 dataset

ChIP H1 ENCFF126NLU 516 bp overlap

CRY1 2 datasets

ChIP U2OS GSE130602.CRY1.U2OS 272 bp overlap

ChIP U2OS_DMSO GSE130506.CRY1.U2OS_DMSO 272 bp overlap

DUX4 2 datasets

Motif DE_12h DE_12h-DUX4_MA0468.1 11 bp overlap

Motif ES_0h ES_0h-DUX4_MA0468.1 11 bp overlap

EP300 1 dataset

ChIP Ishikawa ENCSR000BUE.EP300.Ishikawa 50 bp overlap

ESR1 5 datasets

ChIP Ishikawa ENCSR000BQR.ESR1.Ishikawa 166 bp overlap

ChIP Ishikawa_E2_D538G GSE132426.ESR1.Ishikawa_E2_D538G 80 bp overlap

ChIP Ishikawa_ETV4-KO2_Mili GSE129803.ESR1.Ishikawa_ETV4-KO2_Mili 258 bp overlap

ChIP Ishikawa_ETV4-OE GSE129803.ESR1.Ishikawa_ETV4-OE 313 bp overlap

ChIP breast_tumor_Male_10 GSE104399.ESR1.breast_tumor_Male_10 99 bp overlap

ESRRA 2 datasets

Motif DE_12h DE_12h-ESRRA_MA0592.4 9 bp overlap

Motif ES_0h ES_0h-ESRRA_MA0592.4 9 bp overlap

ESRRB 2 datasets

Motif DE_12h DE_12h-ESRRB_MA0141.4 10 bp overlap

Motif ES_0h ES_0h-ESRRB_MA0141.4 10 bp overlap

Ebf4 2 datasets

Motif DE_12h DE_12h-Ebf4_MA2122.1 11 bp overlap

Motif ES_0h ES_0h-Ebf4_MA2122.1 11 bp overlap

FIGLA 2 datasets

Motif DE_12h DE_12h-FIGLA_MA0820.2 6 bp overlap

Motif ES_0h ES_0h-FIGLA_MA0820.2 6 bp overlap

GATA2 1 dataset

ChIP hiPSC_SLC6ebs GSE107639.GATA2.hiPSC_SLC6ebs 182 bp overlap

HIC2 2 datasets

Motif DE_12h DE_12h-HIC2_MA0738.2 6 bp overlap

Motif ES_0h ES_0h-HIC2_MA0738.2 6 bp overlap

HMBOX1 1 dataset

Motif DE_12h DE_12h-HMBOX1_MA0895.2 7 bp overlap

HNF1A 2 datasets

Motif DE_12h DE_12h-HNF1A_MA0046.3 13 bp overlap

ChIP HEE_1 GSE76376.HNF1A.HEE_1 222 bp overlap

HNF1B 2 datasets

Motif DE_12h DE_12h-HNF1B_MA0153.2 13 bp overlap

ChIP foregut GSE117136.HNF1B.foregut 298 bp overlap

HNF4A 2 datasets

Motif DE_12h DE_12h-HNF4A_MA1494.2 14 bp overlap

Motif ES_0h ES_0h-HNF4A_MA1494.2 14 bp overlap

HOXB4 1 dataset

Motif DE_12h DE_12h-HOXB4_MA1499.2 6 bp overlap

HOXC4 1 dataset

Motif DE_12h DE_12h-HOXC4_MA1504.2 6 bp overlap

HOXD4 1 dataset

Motif DE_12h DE_12h-HOXD4_MA1507.2 6 bp overlap

MAF::NFE2 2 datasets

Motif DE_12h DE_12h-MAFNFE2_MA0501.2 11 bp overlap

Motif ES_0h ES_0h-MAFNFE2_MA0501.2 11 bp overlap

MAFG::NFE2L1 2 datasets

Motif DE_12h DE_12h-MAFGNFE2L1_MA0089.3 11 bp overlap

Motif ES_0h ES_0h-MAFGNFE2L1_MA0089.3 11 bp overlap

MAFK 2 datasets

ChIP H1 ENCFF854XWE 285 bp overlap

ChIP WA01 ENCSR000EBS.MAFK.WA01 217 bp overlap

MED1 1 dataset

ChIP MCF-7_SHRARS GSE60270.MED1.MCF-7_SHRARS 199 bp overlap

MED26 1 dataset

ChIP U2OS_SHCTR GSE73742.MED26.U2OS_SHCTR 239 bp overlap

MEIS1 2 datasets

Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap

Motif ES_0h ES_0h-MEIS1_MA0498.3 5 bp overlap

MEIS2 2 datasets

Motif DE_12h DE_12h-MEIS2_MA0774.1 8 bp overlap

Motif ES_0h ES_0h-MEIS2_MA0774.1 8 bp overlap

MYOD1 2 datasets

ChIP RD GSE137168.MYOD1.RD 203 bp overlap

ChIP RD_shSNAI2 GSE137168.MYOD1.RD_shSNAI2 217 bp overlap

NANOG 1 dataset

ChIP HUES-8 GSE109524.NANOG.HUES-8 414 bp overlap

NEUROD1 1 dataset

ChIP D283-Med GSE92582.NEUROD1.D283-Med 184 bp overlap

NFE2 2 datasets

ChIP K-562 ENCSR552YGL.NFE2.K-562 213 bp overlap

ChIP K-562 ENCSR000FCC.NFE2.K-562 196 bp overlap

NFIC 2 datasets

ChIP Ishikawa ENCFF029AAD 184 bp overlap

ChIP Ishikawa ENCSR000BUT.NFIC.Ishikawa 334 bp overlap

NKX2-3 1 dataset

Motif DE_12h DE_12h-NKX2-3_MA0672.2 8 bp overlap

NKX2-4 1 dataset

Motif DE_12h DE_12h-NKX2-4_MA2003.2 8 bp overlap

NKX2-5 2 datasets

Motif DE_12h DE_12h-NKX2-5_MA0063.3 7 bp overlap

Motif ES_0h ES_0h-NKX2-5_MA0063.3 7 bp overlap

NKX2-8 1 dataset

Motif DE_12h DE_12h-NKX2-8_MA0673.2 8 bp overlap

NR2F1 2 datasets

Motif DE_12h DE_12h-NR2F1_MA1537.2 13 bp overlap

Motif ES_0h ES_0h-NR2F1_MA1537.2 13 bp overlap

NR5A1 2 datasets

Motif DE_12h DE_12h-NR5A1_MA1540.3 12 bp overlap

Motif ES_0h ES_0h-NR5A1_MA1540.3 12 bp overlap

NR6A1 2 datasets

Motif DE_12h DE_12h-NR6A1_MA1541.2 14 bp overlap

Motif ES_0h ES_0h-NR6A1_MA1541.2 14 bp overlap

Nfe2l2 2 datasets

Motif DE_12h DE_12h-Nfe2l2_MA0150.3 11 bp overlap

Motif ES_0h ES_0h-Nfe2l2_MA0150.3 11 bp overlap

Nr2f6 2 datasets

Motif DE_12h DE_12h-Nr2f6_MA0677.2 13 bp overlap

Motif ES_0h ES_0h-Nr2f6_MA0677.2 13 bp overlap

Nr5A2 2 datasets

Motif DE_12h DE_12h-Nr5A2_MA0505.3 9 bp overlap

Motif ES_0h ES_0h-Nr5A2_MA0505.3 9 bp overlap

PBX3 2 datasets

Motif DE_12h DE_12h-PBX3_MA1114.2 11 bp overlap

Motif ES_0h ES_0h-PBX3_MA1114.2 11 bp overlap

PHOX2A 2 datasets

Motif DE_12h DE_12h-PHOX2A_MA0713.1 11 bp overlap

Motif ES_0h ES_0h-PHOX2A_MA0713.1 11 bp overlap

PKNOX1 6 datasets

Motif DE_12h DE_12h-PKNOX1_MA0782.3 10 bp overlap

Motif ES_0h ES_0h-PKNOX1_MA0782.3 10 bp overlap

ChIP K-562 ENCSR115SMW.PKNOX1.K-562 392 bp overlap

ChIP K562 ENCFF236IUS 221 bp overlap

ChIP MCF-7 ENCFF116OCS 258 bp overlap

ChIP MCF-7 ENCSR986XYK.PKNOX1.MCF-7 406 bp overlap

PKNOX2 2 datasets

Motif DE_12h DE_12h-PKNOX2_MA0783.1 12 bp overlap

Motif ES_0h ES_0h-PKNOX2_MA0783.1 12 bp overlap

POU4F2 1 dataset

Motif DE_12h DE_12h-POU4F2_MA0683.2 15 bp overlap

POU5F1 2 datasets

ChIP BJ_INDUCED GSE36570.POU5F1.BJ_INDUCED 145 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 327 bp overlap

PPARD 2 datasets

Motif DE_12h DE_12h-PPARD_MA1550.2 14 bp overlap

Motif ES_0h ES_0h-PPARD_MA1550.2 14 bp overlap

PROP1 2 datasets

Motif DE_12h DE_12h-PROP1_MA0715.1 11 bp overlap

Motif ES_0h ES_0h-PROP1_MA0715.1 11 bp overlap

RBBP5 1 dataset

ChIP WA01 ENCSR000AQC.RBBP5.WA01 144 bp overlap

RBPJ 3 datasets

Motif DE_12h DE_12h-RBPJ_MA1116.2 6 bp overlap

Motif DE_24h DE_24h-RBPJ_MA1116.2 6 bp overlap

Motif ES_0h ES_0h-RBPJ_MA1116.2 6 bp overlap

RELA 1 dataset

ChIP aortic-endothelial-cell_IL1B_D53 GSE139377.RELA.aortic-endothelial-cell_IL1B_D53 135 bp overlap

SIX2 1 dataset

ChIP HEK GSE73865.SIX2.HEK 101 bp overlap

SMAD2 1 dataset

Motif DE_12h DE_12h-SMAD2_MA1964.2 6 bp overlap

SMARCB1 1 dataset

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 215 bp overlap

SMARCC1 1 dataset

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 271 bp overlap

SNAI2 2 datasets

ChIP RD GSE137168.SNAI2.RD 239 bp overlap

ChIP SMS-CTR_shSNAI2 GSE137168.SNAI2.SMS-CTR_shSNAI2 174 bp overlap

SOX18 1 dataset

Motif DE_12h DE_12h-SOX18_MA1563.2 8 bp overlap

SOX21 1 dataset

Motif DE_12h DE_12h-SOX21_MA0866.1 15 bp overlap

SOX4 1 dataset

Motif DE_12h DE_12h-SOX4_MA0867.3 8 bp overlap

SOX8 1 dataset

Motif DE_12h DE_12h-SOX8_MA0868.3 7 bp overlap

SOX9 1 dataset

Motif DE_12h DE_12h-SOX9_MA0077.2 8 bp overlap

SP1 1 dataset

ChIP WA01 ENCSR000BIR.SP1.WA01 143 bp overlap

Sox1 1 dataset

Motif DE_12h DE_12h-Sox1_MA0870.1 15 bp overlap

Sox5 1 dataset

Motif DE_12h DE_12h-Sox5_MA0087.3 8 bp overlap

TCF12 1 dataset

ChIP Ishikawa ENCSR000BUV.TCF12.Ishikawa 138 bp overlap

TEAD3 1 dataset

Motif DE_12h DE_12h-TEAD3_MA0808.1 8 bp overlap

TEAD4 1 dataset

ChIP Ishikawa ENCSR000BSW.TEAD4.Ishikawa 123 bp overlap

TFAP2B 2 datasets

Motif DE_12h DE_12h-TFAP2B_MA0813.1 13 bp overlap

Motif ES_0h ES_0h-TFAP2B_MA0813.1 13 bp overlap

TGIF1 2 datasets

Motif DE_12h DE_12h-TGIF1_MA0796.1 12 bp overlap

Motif ES_0h ES_0h-TGIF1_MA0796.1 12 bp overlap

TGIF2 2 datasets

Motif DE_12h DE_12h-TGIF2_MA0797.1 12 bp overlap

Motif ES_0h ES_0h-TGIF2_MA0797.1 12 bp overlap

TGIF2LX 2 datasets

Motif DE_12h DE_12h-TGIF2LX_MA1571.1 12 bp overlap

Motif ES_0h ES_0h-TGIF2LX_MA1571.1 12 bp overlap

TGIF2LY 2 datasets

Motif DE_12h DE_12h-TGIF2LY_MA1572.1 12 bp overlap

Motif ES_0h ES_0h-TGIF2LY_MA1572.1 12 bp overlap

THRB 2 datasets

Motif DE_12h DE_12h-THRB_MA1574.2 13 bp overlap

Motif ES_0h ES_0h-THRB_MA1574.2 13 bp overlap

ZEB1 2 datasets

Motif DE_12h DE_12h-ZEB1_MA0103.4 6 bp overlap

Motif ES_0h ES_0h-ZEB1_MA0103.4 6 bp overlap

ZNF136 1 dataset

Motif DE_12h DE_12h-ZNF136_MA1588.1 15 bp overlap

ZNF16 2 datasets

Motif DE_12h DE_12h-ZNF16_MA1654.2 21 bp overlap

Motif ES_0h ES_0h-ZNF16_MA1654.2 21 bp overlap

ZNF257 1 dataset

Motif DE_12h DE_12h-ZNF257_MA1710.2 10 bp overlap

ZNF281 1 dataset

Motif DE_12h DE_12h-ZNF281_MA1630.3 10 bp overlap

ZNF35 1 dataset

Motif DE_12h DE_12h-ZNF35_MA2333.1 7 bp overlap

ZNF416 2 datasets

Motif DE_12h DE_12h-ZNF416_MA1979.2 10 bp overlap

Motif ES_0h ES_0h-ZNF416_MA1979.2 10 bp overlap

ZNF582 3 datasets

Motif DE_12h DE_12h-ZNF582_MA1983.2 19 bp overlap

Motif DE_24h DE_24h-ZNF582_MA1983.2 19 bp overlap

Motif ES_0h ES_0h-ZNF582_MA1983.2 19 bp overlap

ZNF768 1 dataset

Motif DE_12h DE_12h-ZNF768_MA1731.2 9 bp overlap

Zic1::Zic2 2 datasets

Motif DE_12h DE_12h-Zic1Zic2_MA1628.2 7 bp overlap

Motif ES_0h ES_0h-Zic1Zic2_MA1628.2 7 bp overlap

Zic2 2 datasets

Motif DE_12h DE_12h-Zic2_MA1629.2 9 bp overlap

Motif ES_0h ES_0h-Zic2_MA1629.2 9 bp overlap

Zic3 2 datasets

Motif DE_12h DE_12h-Zic3_MA0697.3 7 bp overlap

Motif ES_0h ES_0h-Zic3_MA0697.3 7 bp overlap