chr8 : 74,163,711 – 74,164,253

542 bp 63 TFs 5 linked genes

This 542 bp open chromatin element is linked to 5 target genes and is bound by 63 transcription factors.

Linked Genes

5 genes

Gene	Dist. to TSS	Distance	Link type
JPH1	157.3 kb	Distal	Multiome
GDAP1	186.4 kb	Distal	Multiome
TMEM70	187.8 kb	Distal	Multiome
ELOC	191.7 kb	Distal	Multiome
UBE2W	285.2 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

63 transcription factors

AR 1 dataset

ChIP LNCaP GSE80256.AR.LNCaP 144 bp overlap

ARRB1 1 dataset

ChIP LNCaP-C4-2 GSE55615.ARRB1.LNCaP-C4-2 130 bp overlap

ASH2L 1 dataset

ChIP WA01 ENCSR850KIP.ASH2L.WA01 445 bp overlap

BRD3 1 dataset

ChIP MV4-11_IBET151_50nM GSE120715.BRD3.MV4-11_IBET151_50nM 139 bp overlap

Cebpa 2 datasets

ChIP BLaER1 ENCFF031ISE 255 bp overlap

ChIP BLaER1 ENCFF262VBH 227 bp overlap

EED 1 dataset

ChIP ProEs GSE59087.EED.ProEs 206 bp overlap

ELF1 1 dataset

ChIP A-549 GSE122203.ELF1.A-549 131 bp overlap

EP300 1 dataset

ChIP H1 ENCFF927IYK 297 bp overlap

ESR1 2 datasets

ChIP MCF-7_E2 GSE14664.ESR1.MCF-7_E2 95 bp overlap

ChIP MDA-MB-134-VI_ESTROGEN GSE51022.ESR1.MDA-MB-134-VI_ESTROGEN 249 bp overlap

EWSR1-FLI1 2 datasets

Motif DE_12h DE_12h-EWSR1-FLI1_MA0149.1 18 bp overlap

Motif ES_0h ES_0h-EWSR1-FLI1_MA0149.1 18 bp overlap

EZH2 1 dataset

ChIP DND41 ENCSR000ASW.EZH2.DND41 197 bp overlap

Elf5 2 datasets

Motif DE_12h DE_12h-Elf5_MA0136.4 8 bp overlap

Motif ES_0h ES_0h-Elf5_MA0136.4 8 bp overlap

FOXA1 13 datasets

ChIP 22Rv1_CST GSE129951.FOXA1.22Rv1_CST 111 bp overlap

ChIP 22Rv1_CST_Crispr-36 GSE123618.FOXA1.22Rv1_CST_Crispr-36 90 bp overlap

ChIP MCF-7 GSE59530.FOXA1.MCF-7 102 bp overlap

ChIP MCF-7 ERP000380.FOXA1.MCF-7 85 bp overlap

ChIP MCF-7_estrogen_ab2 GSE112969.FOXA1.MCF-7_estrogen_ab2 113 bp overlap

ChIP MCF-7_vehicle_ab2 GSE112969.FOXA1.MCF-7_vehicle_ab2 123 bp overlap

ChIP T-47D_8h GSE137579.FOXA1.T-47D_8h 135 bp overlap

ChIP T-47D_DMSO GSE84593.FOXA1.T-47D_DMSO 56 bp overlap

ChIP T-47D_JC4743 GSE126004.FOXA1.T-47D_JC4743 78 bp overlap

ChIP T-47D_JC4747 GSE126004.FOXA1.T-47D_JC4747 195 bp overlap

ChIP T-47D_JC4748 GSE126004.FOXA1.T-47D_JC4748 77 bp overlap

ChIP T-47D_shRNF2 GSE137579.FOXA1.T-47D_shRNF2 176 bp overlap

ChIP breast-cancer_heregulin GSE101407.FOXA1.breast-cancer_heregulin 244 bp overlap

FOXA2 2 datasets

ChIP CFPAC-1_HNF1B-KO GSE119930.FOXA2.CFPAC-1_HNF1B-KO 164 bp overlap

ChIP liver_CARN1618 ERP008682.FOXA2.liver_CARN1618 57 bp overlap

HOXB4 1 dataset

Motif ES_0h ES_0h-HOXB4_MA1499.2 6 bp overlap

HOXC4 1 dataset

Motif ES_0h ES_0h-HOXC4_MA1504.2 6 bp overlap

HOXD4 1 dataset

Motif ES_0h ES_0h-HOXD4_MA1507.2 6 bp overlap

IKZF2 2 datasets

Motif DE_12h DE_12h-IKZF2_MA2326.1 6 bp overlap

Motif ES_0h ES_0h-IKZF2_MA2326.1 6 bp overlap

JUN 1 dataset

ChIP HAEC_oxpapc_4h GSE89970.JUN.HAEC_oxpapc_4h 130 bp overlap

KLF11 2 datasets

Motif DE_12h DE_12h-KLF11_MA1512.2 10 bp overlap

Motif ES_0h ES_0h-KLF11_MA1512.2 10 bp overlap

KLF13 2 datasets

Motif DE_12h DE_12h-KLF13_MA0657.2 17 bp overlap

Motif ES_0h ES_0h-KLF13_MA0657.2 17 bp overlap

KLF16 2 datasets

Motif DE_12h DE_12h-KLF16_MA0741.1 11 bp overlap

Motif ES_0h ES_0h-KLF16_MA0741.1 11 bp overlap

KLF6 2 datasets

Motif DE_12h DE_12h-KLF6_MA1517.2 9 bp overlap

Motif ES_0h ES_0h-KLF6_MA1517.2 9 bp overlap

KLF9 2 datasets

Motif DE_12h DE_12h-KLF9_MA1107.3 11 bp overlap

Motif ES_0h ES_0h-KLF9_MA1107.3 11 bp overlap

MED1 1 dataset

ChIP HCT-116_shLuc_thaps GSE121798.MED1.HCT-116_shLuc_thaps 176 bp overlap

MEIS1 1 dataset

Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap

MYOG 1 dataset

ChIP RH4_Entinostat-6H GSE116344.MYOG.RH4_Entinostat-6H 181 bp overlap

NANOG 6 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 481 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 500 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 502 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 364 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 203 bp overlap

ChIP hESC GSE18292.NANOG.hESC 170 bp overlap

NCOA3 1 dataset

ChIP MCF-7_E2 ERP000901.NCOA3.MCF-7_E2 148 bp overlap

NKX6-3 1 dataset

Motif ES_0h ES_0h-NKX6-3_MA1530.2 8 bp overlap

PGR 1 dataset

ChIP T-47D_R5020 GSE68355.PGR.T-47D_R5020 279 bp overlap

PHOX2A 1 dataset

Motif ES_0h ES_0h-PHOX2A_MA0713.1 11 bp overlap

POU1F1 1 dataset

Motif ES_0h ES_0h-POU1F1_MA0784.3 14 bp overlap

POU2F1::SOX2 1 dataset

Motif ES_0h ES_0h-POU2F1SOX2_MA1962.1 17 bp overlap

POU3F3 1 dataset

Motif ES_0h ES_0h-POU3F3_MA0788.1 13 bp overlap

POU5F1 4 datasets

ChIP HUES-8 GSE109524.POU5F1.HUES-8 479 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 542 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 479 bp overlap

ChIP hiPSC GSE56567.POU5F1.hiPSC 325 bp overlap

POU6F1 1 dataset

Motif ES_0h ES_0h-POU6F1_MA1549.2 7 bp overlap

Pou5f1::Sox2 1 dataset

Motif ES_0h ES_0h-Pou5f1Sox2_MA0142.1 15 bp overlap

RAD21 1 dataset

ChIP HAP1_CTCF GSE126634.RAD21.HAP1_CTCF 343 bp overlap

RBAK 1 dataset

ChIP HEK293T GSE78099.RBAK.HEK293T 187 bp overlap

RBBP5 1 dataset

ChIP WA01 ENCSR000AQC.RBBP5.WA01 135 bp overlap

REST 1 dataset

Motif DE_12h DE_12h-REST_MA0138.3 20 bp overlap

SIX2 1 dataset

Motif ES_0h ES_0h-SIX2_MA1119.2 11 bp overlap

SMARCA4 2 datasets

ChIP hiPSC GSE124903.SMARCA4.hiPSC 140 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 335 bp overlap

SMARCB1 1 dataset

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 271 bp overlap

SMARCC1 1 dataset

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 352 bp overlap

SOX2 2 datasets

ChIP hESC GSE18292.SOX2.hESC 95 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 379 bp overlap

SRF 1 dataset

ChIP MCF-7 ENCSR000BVA.SRF.MCF-7 83 bp overlap

Stat4 2 datasets

Motif DE_12h DE_12h-Stat4_MA0518.2 10 bp overlap

Motif ES_0h ES_0h-Stat4_MA0518.2 10 bp overlap

TCF12 1 dataset

ChIP WA01 ENCSR000BIT.TCF12.WA01 175 bp overlap

TCF3 1 dataset

ChIP NPC GSE154479.TCF3.NPC 414 bp overlap

TFAP2C 1 dataset

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 399 bp overlap

TRIM28 2 datasets

ChIP WA01 GSE78099.TRIM28.WA01 203 bp overlap

ChIP hESC GSE115387.TRIM28.hESC 287 bp overlap

USF1 1 dataset

ChIP WA01 ENCSR000BIU.USF1.WA01 131 bp overlap

ZKSCAN1 1 dataset

Motif ES_0h ES_0h-ZKSCAN1_MA1585.2 9 bp overlap

ZKSCAN5 2 datasets

Motif DE_12h DE_12h-ZKSCAN5_MA1652.2 9 bp overlap

Motif ES_0h ES_0h-ZKSCAN5_MA1652.2 9 bp overlap

ZNF143 1 dataset

ChIP WA01 ENCSR000EBW.ZNF143.WA01 222 bp overlap

ZNF207 1 dataset

ChIP WA09 GSE118632.ZNF207.WA09 234 bp overlap

ZNF211 1 dataset

Motif ES_0h ES_0h-ZNF211_MA1974.2 10 bp overlap

ZNF462 2 datasets

ChIP GM23338 ENCFF896CCA 251 bp overlap

ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 457 bp overlap

ZNF528 2 datasets

Motif DE_12h DE_12h-ZNF528_MA1597.1 17 bp overlap

Motif ES_0h ES_0h-ZNF528_MA1597.1 17 bp overlap

ZNF766 1 dataset

Motif DE_12h DE_12h-ZNF766_MA2098.1 9 bp overlap

ZNF85 1 dataset

Motif ES_0h ES_0h-ZNF85_MA1720.2 12 bp overlap