chr1:16,938,744–16,939,855

chr1 : 16,938,744 – 16,939,855

1,111 bp 81 TFs 7 linked genes

This 1.1 kb open chromatin element is linked to 7 target genes and is bound by 81 transcription factors.

Linked Genes

7 genes

Gene	Expression	Dist. to TSS	Distance	Link type
CROCC		17.4 kb	Distal	Multiome+HiCAR
MFAP2		41.3 kb	Distal	Multiome
ENSG00000238142		49.7 kb	Distal	Multiome
ATP13A2		72.6 kb	Distal	Multiome
SDHB		114.9 kb	Distal	Multiome
ENSG00000290851		180.0 kb	Distal	Multiome
NBPF1		325.7 kb	Distal	Multiome+HiCAR

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

81 transcription factors

ChIP prostate_cancer-associated-fibroblasts GSE90772.AR.prostate_cancer-associated-fibroblasts 133 bp overlap

ASH2L 1 dataset

ChIP WA01 ENCSR850KIP.ASH2L.WA01 383 bp overlap

Ahr::Arnt 1 dataset

Motif DE_72h DE_72h-AhrArnt_MA0006.2 5 bp overlap

BCOR 3 datasets

ChIP K562 ENCFF343XWA 264 bp overlap

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 172 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 312 bp overlap

BRD4 5 datasets

ChIP COLO-741 GSE73319.BRD4.COLO-741 154 bp overlap

ChIP MCF-10A ERP003925.BRD4.MCF-10A 605 bp overlap

ChIP T-47D ERP003925.BRD4.T-47D 464 bp overlap

ChIP hESC GSE33281.BRD4.hESC 61 bp overlap

ChIP hESC GSE33281.BRD4.hESC 85 bp overlap

ChIP ME-1 GSE46044.CBFB.ME-1 270 bp overlap

ChIP HCT-116 GSE72622.CDK9.HCT-116 415 bp overlap

ChIP hMSC-TERT GSE89179.CHD1.hMSC-TERT 204 bp overlap

CTCF 2 datasets

ChIP GM23338 ENCFF772DML 201 bp overlap

ChIP hESC_NAIVE GSE69646.CTCF.hESC_NAIVE 274 bp overlap

CTCFL 1 dataset

ChIP K-562 GSE70764.CTCFL.K-562 264 bp overlap

Cebpa 3 datasets

ChIP BLaER1 ENCFF031ISE 292 bp overlap

ChIP BLaER1 ENCFF335XTP 108 bp overlap

ChIP BLaER1 ENCFF460KDD 251 bp overlap

DNMT3B 1 dataset

ChIP HUES-8_TripleKO-TET1-2-3 GSE99346.DNMT3B.HUES-8_TripleKO-TET1-2-3 173 bp overlap

ChIP ME-1 GSE46044.ELF1.ME-1 227 bp overlap

ChIP CD34_NR29 GSE23730.ERG.CD34_NR29 265 bp overlap

ChIP SKNO-1 GSE23730.ERG.SKNO-1 170 bp overlap

ESR1 3 datasets

ChIP Ishikawa_siNTC-72h GSE129803.ESR1.Ishikawa_siNTC-72h 238 bp overlap

ChIP Ishikawa_siNTC-96h GSE129803.ESR1.Ishikawa_siNTC-96h 224 bp overlap

ChIP MDA-MB-134-VI_ESTROGEN GSE51022.ESR1.MDA-MB-134-VI_ESTROGEN 248 bp overlap

ETV2::FOXI1 1 dataset

Motif DE_72h DE_72h-ETV2FOXI1_MA1942.2 11 bp overlap

ChIP UAE_ZINC GSE23730.FLI1.UAE_ZINC 293 bp overlap

GLIS3 1 dataset

ChIP H9_plus GSE109562.GLIS3.H9_plus 389 bp overlap

GTF2I 1 dataset

ChIP K562 ENCFF539BYI 229 bp overlap

HDAC2 1 dataset

ChIP WA01 ENCSR000AVB.HDAC2.WA01 220 bp overlap

HEXIM1 1 dataset

ChIP HCT-116 GSE72622.HEXIM1.HCT-116 282 bp overlap

INSM1 1 dataset

Motif DE_72h DE_72h-INSM1_MA0155.1 12 bp overlap

ChIP DE_D1 S08-DE-d1-JUN-exp1 269 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 379 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 200 bp overlap

ChIP WTC11 ENCFF581TPB 466 bp overlap

KDM1A 2 datasets

ChIP H1 ENCFF696SGD 283 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.KDM1A.pancreatic-progenitor_PP1 171 bp overlap

KDM4A 1 dataset

ChIP WA01 ENCSR000AVC.KDM4A.WA01 193 bp overlap

Motif DE_72h DE_72h-KLF5_MA0599.1 10 bp overlap

ChIP WTC11 ENCFF223QFY 206 bp overlap

ChIP HeLa GSE41006.MBD2.HeLa 110 bp overlap

ChIP P493-6_24HR GSE125863.MYC.P493-6_24HR 298 bp overlap

NANOG 2 datasets

ChIP WA01 ENCSR000BMT.NANOG.WA01 120 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 264 bp overlap

NCAPH2 1 dataset

ChIP HEK293 GSE97540.NCAPH2.HEK293 389 bp overlap

PCGF1 1 dataset

ChIP WA01 GSE104690.PCGF1.WA01 184 bp overlap

POLR2A 1 dataset

ChIP H1 ENCFF833NJP 359 bp overlap

POU5F1 4 datasets

ChIP BG03 GSE21614.POU5F1.BG03 187 bp overlap

ChIP DE_D1 DED1-OCT4_Batch_II 1111 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 238 bp overlap

ChIP hiPSC GSE56567.POU5F1.hiPSC 172 bp overlap

POU5F1_M 2 datasets

ChIP DE_D1 DED1-OCT4-M_Batch_II 654 bp overlap

ChIP DE_D1 DED1-OCT4-M_Batch_II 196 bp overlap

PRDM14 1 dataset

ChIP NCCIT GSE71675.PRDM14.NCCIT 316 bp overlap

PTBP1 1 dataset

ChIP K-562 ENCSR948KMB.PTBP1.K-562 163 bp overlap

RBBP5 1 dataset

ChIP WA01 ENCSR000AQC.RBBP5.WA01 277 bp overlap

RBFOX2 1 dataset

ChIP K-562 ENCSR822LBD.RBFOX2.K-562 231 bp overlap

RORC 2 datasets

ChIP HCC70 GSE126380.RORC.HCC70 568 bp overlap

ChIP HCC70_XY018 GSE126380.RORC.HCC70_XY018 542 bp overlap

RUNX1 1 dataset

ChIP ME-1 GSE46044.RUNX1.ME-1 217 bp overlap

ChIP TSU-1621MT GSE60477.RXR.TSU-1621MT 207 bp overlap

SIN3A 3 datasets

ChIP WA01 ENCSR000EBO.SIN3A.WA01 146 bp overlap

ChIP hiPSC_IA12 GSE106870.SIN3A.hiPSC_IA12 162 bp overlap

ChIP hiPSC_IB12 GSE106870.SIN3A.hiPSC_IB12 241 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 321 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 204 bp overlap

SMAD2_3 3 datasets

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 301 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 246 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 311 bp overlap

SMAD3 1 dataset

ChIP hESC GSE29422.SMAD3.hESC 164 bp overlap

SMARCA4 2 datasets

ChIP MCF-10A GSE74716.SMARCA4.MCF-10A 188 bp overlap

ChIP hiPSC GSE124903.SMARCA4.hiPSC 225 bp overlap

SMARCB1 1 dataset

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 170 bp overlap

SMARCC1 2 datasets

ChIP hiPSC GSE124903.SMARCC1.hiPSC 211 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 226 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 466 bp overlap

Motif DE_72h DE_72h-SP1_MA0079.5 9 bp overlap

ChIP WTC11 ENCFF688PEU 501 bp overlap

ChIP WTC11 ENCFF688PEU 501 bp overlap

Motif DE_72h DE_72h-SP4_MA0685.2 9 bp overlap

Motif DE_72h DE_72h-SP4_MA0685.2 9 bp overlap

Motif DE_72h DE_72h-SP5_MA1965.2 6 bp overlap

Motif DE_72h DE_72h-SP5_MA1965.2 6 bp overlap

SPDEF 1 dataset

Motif DE_72h DE_72h-SPDEF_MA0686.2 10 bp overlap

SREBP2 2 datasets

ChIP HCC70 GSE126380.SREBP2.HCC70 560 bp overlap

ChIP HCC70_XY018 GSE126380.SREBP2.HCC70_XY018 532 bp overlap

TBL1X 1 dataset

ChIP HEK293T GSE35197.TBL1X.HEK293T 178 bp overlap

ChIP WA01 ENCSR000ECB.TBP.WA01 174 bp overlap

TFAP2C 2 datasets

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 534 bp overlap

ChIP UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc 235 bp overlap

TFAP4 1 dataset

ChIP K562 ENCFF727PXG 510 bp overlap

TFIIIC 1 dataset

ChIP HEK293 GSE119418.TFIIIC.HEK293 459 bp overlap

TGIF2 1 dataset

ChIP WTC11 ENCFF649SHI 427 bp overlap

ChIP WTC11 ENCFF359JCU 480 bp overlap

ChIP breast-organoid GSE113909.TP63.breast-organoid 148 bp overlap

TRIM28 1 dataset

ChIP HCT-116 GSE72622.TRIM28.HCT-116 195 bp overlap

ChIP SMMC-7721 GSE126982.WDR5.SMMC-7721 302 bp overlap

Motif DE_72h DE_72h-Wt1_MA1627.2 10 bp overlap

Motif DE_72h DE_72h-Wt1_MA1627.2 10 bp overlap

ChIP Huh-7 GSE97411.YY1.Huh-7 171 bp overlap

ZBTB33 3 datasets

ChIP K562 ENCFF427SDV 442 bp overlap

ChIP K562 ENCFF427SDV 106 bp overlap

ChIP K562 ENCFF875HLX 421 bp overlap

ZBTB7A 3 datasets

ChIP K-562 GSE103445.ZBTB7A.K-562 219 bp overlap

ChIP K-562 ENCSR000BME.ZBTB7A.K-562 181 bp overlap

ChIP K562 ENCFF579ZGM 401 bp overlap

ZFP36 4 datasets

ChIP HeLa-S3 ENCFF281CEA 174 bp overlap

ChIP HeLa-S3 ENCSR184MFH.ZFP36.HeLa-S3 187 bp overlap

ChIP K-562 ENCSR776CYN.ZFP36.K-562 234 bp overlap

ChIP K562 ENCFF255RZG 191 bp overlap

ZMYM3 1 dataset

ChIP K562 ENCFF361LXT 225 bp overlap

ZNF143 1 dataset

ChIP WA01 ENCSR000EBW.ZNF143.WA01 171 bp overlap

ZNF148 1 dataset

Motif DE_72h DE_72h-ZNF148_MA1653.2 10 bp overlap

ZNF184 1 dataset

ChIP WTC11 ENCFF352POG 488 bp overlap

ZNF263 3 datasets

Motif DE_72h DE_72h-ZNF263_MA0528.3 7 bp overlap

Motif DE_72h DE_72h-ZNF263_MA0528.3 7 bp overlap

ChIP WTC11 ENCFF893RTM 437 bp overlap

ZNF281 2 datasets

Motif DE_72h DE_72h-ZNF281_MA1630.3 10 bp overlap

ChIP WTC11 ENCFF551GAV 367 bp overlap

ZNF423 1 dataset

ChIP WTC11 ENCFF574PBR 317 bp overlap

ZNF436 1 dataset

ChIP HEK293 GSE76494.ZNF436.HEK293 206 bp overlap

ZNF684 1 dataset

Motif DE_72h DE_72h-ZNF684_MA1600.2 14 bp overlap

ZNF92 1 dataset

ChIP retina_pigment GSE60024.ZNF92.retina_pigment 108 bp overlap