chr7 : 125,927,546 – 125,927,895

349 bp 97 TFs 1 linked gene

This 349 bp open chromatin element is linked to ENSG00000197462 and is bound by 97 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000197462		9.7 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

97 transcription factors

ARID1A 1 dataset

ChIP NGP GSE134626.ARID1A.NGP 324 bp overlap

ARNT 1 dataset

ChIP SK-MEL-28 GSE85352.ARNT.SK-MEL-28 349 bp overlap

ASXL3 1 dataset

ChIP NCI-H1963_Ab1 GSE145028.ASXL3.NCI-H1963_Ab1 319 bp overlap

Arid3a 1 dataset

Motif DE_12h DE_12h-Arid3a_MA0151.1 6 bp overlap

BHLHE22 1 dataset

Motif DE_12h DE_12h-BHLHE22_MA1635.2 6 bp overlap

BRD4 7 datasets

ChIP Kelly_sensitive GSE103030.BRD4.Kelly_sensitive 135 bp overlap

ChIP NCI-H1963 GSE145028.BRD4.NCI-H1963 340 bp overlap

ChIP NCI-H1963_dBET6 GSE145028.BRD4.NCI-H1963_dBET6 266 bp overlap

ChIP NCI-H1963_shASXL3 GSE145028.BRD4.NCI-H1963_shASXL3 171 bp overlap

ChIP RH4_shscr GSE140115.BRD4.RH4_shscr 265 bp overlap

ChIP cortical-interneuron_R133C_KCl-pos_JQ1-neg GSE117508.BRD4.cortical-interneuron_R133C_KCl-pos_JQ1-neg 183 bp overlap

ChIP hESC GSE33281.BRD4.hESC 61 bp overlap

Bhlha15 1 dataset

Motif DE_12h DE_12h-Bhlha15_MA1472.3 8 bp overlap

CHD7 1 dataset

ChIP hiPSC_derived_lt-NES GSE108506.CHD7.hiPSC_derived_lt-NES 349 bp overlap

CREB1 1 dataset

Motif DE_12h DE_12h-CREB1_MA0018.5 8 bp overlap

CTCF 1 dataset

ChIP HAP1_clone21_CTCF-CRISPR GSE152721.CTCF.HAP1_clone21_CTCF-CRISPR 349 bp overlap

EBF1 1 dataset

ChIP GM12878 ENCFF167CZS 296 bp overlap

EBF3_P177L 1 dataset

ChIP SK-N-SH GSE90682.EBF3_P177L.SK-N-SH 235 bp overlap

EGR2 1 dataset

Motif DE_12h DE_12h-EGR2_MA0472.2 11 bp overlap

ELK1::HOXB13 1 dataset

Motif DE_12h DE_12h-ELK1HOXB13_MA1932.2 15 bp overlap

EP300 2 datasets

ChIP neural ENCSR843ZUP.EP300.neural 349 bp overlap

ChIP neural cell ENCFF442QNK 229 bp overlap

ERF::HOXB13 1 dataset

Motif DE_12h DE_12h-ERFHOXB13_MA1937.2 13 bp overlap

ERG 2 datasets

ChIP VCaP GSE49091.ERG.VCaP 128 bp overlap

ChIP VCaP_R1881 GSE49091.ERG.VCaP_R1881 315 bp overlap

EZH2_phosphoT487 1 dataset

ChIP neuron_bipolar_doxy_4d ENCSR886KKK.EZH2_phosphoT487.neuron_bipolar_doxy_4d 349 bp overlap

FLI1 4 datasets

ChIP A-673_1_KRAB_GFP GSE106914.FLI1.A-673_1_KRAB_GFP 349 bp overlap

ChIP A-673_2_KRAB_eSOX2_1 GSE106914.FLI1.A-673_2_KRAB_eSOX2_1 292 bp overlap

ChIP A-673_D14 GSE129155.FLI1.A-673_D14 282 bp overlap

ChIP A-673_D17 GSE129155.FLI1.A-673_D17 349 bp overlap

FOXA2 1 dataset

ChIP DE DE-FOXA2-2 62 bp overlap

FOXD3 1 dataset

Motif DE_12h DE_12h-FOXD3_MA0041.3 14 bp overlap

FOXH1 1 dataset

Motif DE_12h DE_12h-FOXH1_MA0479.2 8 bp overlap

GATA2 2 datasets

Motif DE_12h DE_12h-GATA2_MA0036.4 7 bp overlap

ChIP SH-SY5Y ENCFF485YIB 349 bp overlap

GATA3 3 datasets

ChIP Kelly GSE94822.GATA3.Kelly 260 bp overlap

ChIP Kelly GSE65664.GATA3.Kelly 257 bp overlap

ChIP SH-SY5Y ENCFF475HYF 105 bp overlap

GATA4 6 datasets

ChIP DE DE-GATA4-1 302 bp overlap

ChIP DE DE-GATA4-2 281 bp overlap

Motif DE_12h DE_12h-GATA4_MA0482.3 8 bp overlap

ChIP Hep-G2 GSE135714.GATA4.Hep-G2 239 bp overlap

ChIP foregut GSE117136.GATA4.foregut 326 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 349 bp overlap

GATA5 1 dataset

Motif DE_12h DE_12h-GATA5_MA0766.3 8 bp overlap

GATA6 11 datasets

ChIP DE DE-GATA6-1 231 bp overlap

ChIP DE DE-GATA6-2 319 bp overlap

Motif DE_12h DE_12h-GATA6_MA1104.3 8 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 349 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 349 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 349 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 328 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 349 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 349 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 270 bp overlap

ChIP foregut GSE117136.GATA6.foregut 293 bp overlap

GLI3 1 dataset

Motif DE_12h DE_12h-GLI3_MA1491.3 15 bp overlap

Gata3 1 dataset

Motif DE_12h DE_12h-Gata3_MA0037.5 8 bp overlap

Gli2 1 dataset

Motif DE_12h DE_12h-Gli2_MA0734.4 9 bp overlap

HAND2 1 dataset

ChIP SK-N-BE2-C GSE94822.HAND2.SK-N-BE2-C 349 bp overlap

HIC2 1 dataset

Motif DE_12h DE_12h-HIC2_MA0738.2 6 bp overlap

HOXD12::ELK1 1 dataset

Motif DE_12h DE_12h-HOXD12ELK1_MA1958.2 13 bp overlap

Hic1 1 dataset

Motif DE_12h DE_12h-Hic1_MA0739.2 8 bp overlap

Hmga1 1 dataset

Motif DE_12h DE_12h-Hmga1_MA2124.1 8 bp overlap

IKZF2 1 dataset

Motif DE_12h DE_12h-IKZF2_MA2326.1 6 bp overlap

IRF2 1 dataset

Motif DE_12h DE_12h-IRF2_MA0051.2 16 bp overlap

ISL1 1 dataset

ChIP SK-N-BE2-C GSE94822.ISL1.SK-N-BE2-C 349 bp overlap

KDM1A 2 datasets

ChIP NCI-H526_DMSO GSE66297.KDM1A.NCI-H526_DMSO 285 bp overlap

ChIP SH-SY5Y_B3 GSE58258.KDM1A.SH-SY5Y_B3 224 bp overlap

KLF9 1 dataset

Motif DE_12h DE_12h-KLF9_MA1107.3 11 bp overlap

MORC2 1 dataset

ChIP H9 GSE95374.MORC2.H9 280 bp overlap

MRTFB 1 dataset

ChIP A-673-clone-Asp114 GSE92738.MRTFB.A-673-clone-Asp114 328 bp overlap

MTA2 1 dataset

ChIP RH4 GSE155861.MTA2.RH4 349 bp overlap

MXI1 1 dataset

Motif DE_12h DE_12h-MXI1_MA1108.3 6 bp overlap

MYCN 1 dataset

ChIP Kelly GSE94822.MYCN.Kelly 209 bp overlap

MYF5 1 dataset

Motif DE_12h DE_12h-MYF5_MA1641.2 8 bp overlap

MYOG 1 dataset

Motif DE_12h DE_12h-MYOG_MA0500.3 8 bp overlap

NANOG 3 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 349 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 219 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 282 bp overlap

NR1H4::RXRA 1 dataset

Motif DE_12h DE_12h-NR1H4RXRA_MA1146.2 13 bp overlap

NR2F1 1 dataset

Motif DE_12h DE_12h-NR2F1_MA1538.1 15 bp overlap

NR2F6 1 dataset

Motif DE_12h DE_12h-NR2F6_MA1539.1 15 bp overlap

NR4A2::RXRA 1 dataset

Motif DE_12h DE_12h-NR4A2RXRA_MA1147.2 13 bp overlap

Neurod2 1 dataset

Motif DE_12h DE_12h-Neurod2_MA1993.2 6 bp overlap

Nr2e1 1 dataset

Motif DE_12h DE_12h-Nr2e1_MA0676.1 9 bp overlap

Olig2 1 dataset

Motif DE_12h DE_12h-Olig2_MA1997.2 6 bp overlap

PAX1 1 dataset

Motif DE_12h DE_12h-PAX1_MA0779.2 16 bp overlap

PAX2 1 dataset

Motif DE_12h DE_12h-PAX2_MA0067.3 16 bp overlap

PAX3-FOXO1 1 dataset

ChIP RH3 GSE83726.PAX3-FOXO1.RH3 191 bp overlap

PAX8 1 dataset

Motif DE_12h DE_12h-PAX8_MA2094.1 16 bp overlap

PBX1 1 dataset

Motif DE_12h DE_12h-PBX1_MA0070.2 9 bp overlap

POLR2A 2 datasets

ChIP SK-N-MC ENCFF088IVG 143 bp overlap

ChIP neural cell ENCFF604SPB 201 bp overlap

POU2F1::SOX2 1 dataset

Motif DE_12h DE_12h-POU2F1SOX2_MA1962.1 17 bp overlap

POU2F3 1 dataset

ChIP NCI-H1048 GSE115123.POU2F3.NCI-H1048 245 bp overlap

POU4F2 2 datasets

Motif DE_12h DE_12h-POU4F2_MA0683.2 15 bp overlap

ChIP HNPC_DIF GSE74814.POU4F2.HNPC_DIF 317 bp overlap

Ptf1A 2 datasets

Motif DE_12h DE_12h-Ptf1A_MA1619.2 8 bp overlap

Motif DE_12h DE_12h-Ptf1A_MA1620.2 8 bp overlap

RAD21 5 datasets

ChIP HAP1 GSE126634.RAD21.HAP1 349 bp overlap

ChIP HAP1 GSE152721.RAD21.HAP1 349 bp overlap

ChIP HAP1_clone25 GSE152721.RAD21.HAP1_clone25 336 bp overlap

ChIP neural ENCSR198ZYJ.RAD21.neural 349 bp overlap

ChIP neural cell ENCFF564MOT 349 bp overlap

RBBP4 1 dataset

ChIP SCMC GSE155861.RBBP4.SCMC 272 bp overlap

REST 2 datasets

ChIP neural ENCSR000BTV.REST.neural 249 bp overlap

ChIP neural cell ENCFF882LXX 349 bp overlap

RXRA::VDR 1 dataset

Motif DE_12h DE_12h-RXRAVDR_MA0074.1 15 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 327 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 324 bp overlap

SMAD2_3 3 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 250 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 342 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 290 bp overlap

SMARCA4 4 datasets

ChIP NPC_siCT GSE122631.SMARCA4.NPC_siCT 349 bp overlap

ChIP NPC_siSOX GSE122631.SMARCA4.NPC_siSOX 325 bp overlap

ChIP NSC GSE125033.SMARCA4.NSC 349 bp overlap

ChIP hiPSC GSE124903.SMARCA4.hiPSC 231 bp overlap

SMARCB1 1 dataset

ChIP hiPSC GSE124903.SMARCB1.hiPSC 246 bp overlap

SMARCC1 3 datasets

ChIP SK-N-MC GSE94275.SMARCC1.SK-N-MC 261 bp overlap

ChIP SK-N-MC_shGFP GSE94275.SMARCC1.SK-N-MC_shGFP 177 bp overlap

ChIP hiPSC GSE124903.SMARCC1.hiPSC 192 bp overlap

SMC1A-B 1 dataset

ChIP TC-32 GSE115250.SMC1A-B.TC-32 253 bp overlap

SMC3 2 datasets

ChIP neural ENCSR404BPV.SMC3.neural 320 bp overlap

ChIP neural cell ENCFF795YGY 349 bp overlap

SOX2 5 datasets

ChIP HNSC GSE69479.SOX2.HNSC 349 bp overlap

ChIP hiPSC GSE67282.SOX2.hiPSC 329 bp overlap

ChIP hiPSC_INHI GSE67282.SOX2.hiPSC_INHI 303 bp overlap

ChIP hiPSC_KDP53 GSE67282.SOX2.hiPSC_KDP53 322 bp overlap

ChIP hiPSC_KDP53_INHI GSE67282.SOX2.hiPSC_KDP53_INHI 349 bp overlap

Stat6 1 dataset

Motif DE_12h DE_12h-Stat6_MA0520.2 10 bp overlap

TBX2 1 dataset

ChIP Kelly GSE94822.TBX2.Kelly 250 bp overlap

TCF7L2 4 datasets

Motif DE_12h DE_12h-TCF7L2_MA0523.2 9 bp overlap

ChIP HEK293 ENCFF513JQN 349 bp overlap

ChIP HEK293 ENCSR000EUY.TCF7L2.HEK293 349 bp overlap

TFAP2A 1 dataset

Motif DE_12h DE_12h-TFAP2A_MA0003.5 9 bp overlap

TFAP2C 1 dataset

Motif DE_12h DE_12h-TFAP2C_MA0814.3 9 bp overlap

TFAP4::FLI1 1 dataset

Motif DE_12h DE_12h-TFAP4FLI1_MA1967.2 14 bp overlap

TP53 1 dataset

Motif DE_12h DE_12h-TP53_MA0106.3 18 bp overlap

TRPS1 1 dataset

Motif DE_12h DE_12h-TRPS1_MA1970.2 8 bp overlap

Tcf12 1 dataset

Motif DE_12h DE_12h-Tcf12_MA0521.3 6 bp overlap

Tcf21 1 dataset

Motif DE_12h DE_12h-Tcf21_MA0832.2 10 bp overlap

Twist2 1 dataset

Motif DE_12h DE_12h-Twist2_MA0633.3 6 bp overlap

ZFP42 1 dataset

Motif DE_12h DE_12h-ZFP42_MA1651.2 13 bp overlap

ZNF136 1 dataset

Motif DE_12h DE_12h-ZNF136_MA1588.1 15 bp overlap

ZNF317 1 dataset

Motif DE_12h DE_12h-ZNF317_MA1593.2 8 bp overlap

ZNF35 1 dataset

Motif DE_12h DE_12h-ZNF35_MA2333.1 7 bp overlap

ZNF354C 1 dataset

Motif DE_12h DE_12h-ZNF354C_MA0130.1 6 bp overlap

ZNF524 1 dataset

Motif DE_12h DE_12h-ZNF524_MA2096.1 9 bp overlap

ZNF558 1 dataset

Motif DE_12h DE_12h-ZNF558_MA2335.1 29 bp overlap

ZSCAN4 1 dataset

Motif DE_12h DE_12h-ZSCAN4_MA1155.1 15 bp overlap

Zfp335 1 dataset

Motif DE_12h DE_12h-Zfp335_MA2002.2 7 bp overlap