chr6 : 16,174,497 – 16,175,068
571 bp 94 TFs 4 linked genes
This 571 bp open chromatin element is linked to 4 target genes and is bound by 94 transcription factors.
Linked Genes
4 genes
Link type
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
MYLIP 45.8 kb Distal Multiome
GMPR 63.7 kb Distal Multiome
ENSG00000282024 88.1 kb Distal Multiome
DTNBP1 511.8 kb Distal Multiome+HiCAR
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr6:16,169,497 – 16,180,068
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
94 transcription factors
Source
Cell type
ASH2L 1 dataset
ChIP WA01 ENCSR850KIP.ASH2L.WA01 355 bp overlap
Atoh1 2 datasets
Motif DE_60h DE_60h-Atoh1_MA1467.3 7 bp overlap
Motif DE_72h DE_72h-Atoh1_MA1467.3 7 bp overlap
BCOR 2 datasets
ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 149 bp overlap
ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 161 bp overlap
CDX2 1 dataset
ChIP Caco-2_DIFF GSE23436.CDX2.Caco-2_DIFF 208 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 247 bp overlap
ESR1 5 datasets
ChIP T-47D ENCSR000BJS.ESR1.T-47D 138 bp overlap
ChIP T-47D ENCSR000BKN.ESR1.T-47D 84 bp overlap
ChIP T-47D_D538G GSE148277.ESR1.T-47D_D538G 217 bp overlap
ChIP T-47D_D538G_E2 GSE148277.ESR1.T-47D_D538G_E2 263 bp overlap
ChIP primary-endometrium-cancer_E1_DSG GSE114737.ESR1.primary-endometrium-cancer_E1_DSG 267 bp overlap
ETS1 1 dataset
ChIP cardiomyocyte_D2 GSE129986.ETS1.cardiomyocyte_D2 168 bp overlap
FOXA1 8 datasets
Motif DE_12h DE_12h-FOXA1_MA0148.5 8 bp overlap
Motif DE_72h DE_72h-FOXA1_MA0148.5 8 bp overlap
ChIP T-47D_CR3flp GSE99479.FOXA1.T-47D_CR3flp 163 bp overlap
ChIP T-47D_E2_TAM ERP000380.FOXA1.T-47D_E2_TAM 129 bp overlap
ChIP T-47D_JC4748 GSE126004.FOXA1.T-47D_JC4748 143 bp overlap
ChIP liver ERP002306.FOXA1.liver 143 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.FOXA1.pancreatic-progenitor_PP1 464 bp overlap
ChIP prostate_2483_T GSE130408.FOXA1.prostate_2483_T 229 bp overlap
FOXA2 5 datasets
ChIP Caco-2 GSE66218.FOXA2.Caco-2 205 bp overlap
ChIP DE DE-FOXA2-1 556 bp overlap
ChIP DE DE-FOXA2-2 571 bp overlap
ChIP liver_CARN1618 ERP008682.FOXA2.liver_CARN1618 195 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.FOXA2.pancreatic-progenitor_PP1 351 bp overlap
FOXB1 2 datasets
Motif DE_12h DE_12h-FOXB1_MA0845.1 11 bp overlap
Motif DE_72h DE_72h-FOXB1_MA0845.1 11 bp overlap
FOXC1 2 datasets
Motif DE_12h DE_12h-FOXC1_MA0032.2 11 bp overlap
Motif DE_72h DE_72h-FOXC1_MA0032.2 11 bp overlap
FOXC2 2 datasets
Motif DE_12h DE_12h-FOXC2_MA0846.2 11 bp overlap
Motif DE_72h DE_72h-FOXC2_MA0846.2 11 bp overlap
FOXO6 2 datasets
Motif DE_12h DE_12h-FOXO6_MA0849.1 7 bp overlap
Motif DE_72h DE_72h-FOXO6_MA0849.1 7 bp overlap
GATA4 4 datasets
ChIP DE DE-GATA4-1 526 bp overlap
ChIP DE DE-GATA4-2 571 bp overlap
ChIP foregut GSE117136.GATA4.foregut 474 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 491 bp overlap
GATA6 10 datasets
ChIP DE DE-GATA6-1 543 bp overlap
ChIP DE DE-GATA6-2 571 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 571 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 497 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 546 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 571 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 571 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 571 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 493 bp overlap
ChIP foregut GSE117136.GATA6.foregut 432 bp overlap
GRHL2 1 dataset
ChIP T-47D GSE99680.GRHL2.T-47D 144 bp overlap
HAND2 2 datasets
Motif DE_60h DE_60h-HAND2_MA1638.2 6 bp overlap
Motif DE_72h DE_72h-HAND2_MA1638.2 6 bp overlap
HMBOX1 2 datasets
Motif DE_60h DE_60h-HMBOX1_MA0895.2 7 bp overlap
Motif DE_72h DE_72h-HMBOX1_MA0895.2 7 bp overlap
HNF1A 2 datasets
ChIP HEE_1 GSE76376.HNF1A.HEE_1 200 bp overlap
ChIP HEE_5 GSE76376.HNF1A.HEE_5 123 bp overlap
HNF1B 2 datasets
ChIP H9 ERP004206.HNF1B.H9 183 bp overlap
ChIP foregut GSE117136.HNF1B.foregut 526 bp overlap
HNF4A 3 datasets
ChIP Caco-2_DIFF GSE23436.HNF4A.Caco-2_DIFF 173 bp overlap
ChIP Caco-2_PROLIF GSE23436.HNF4A.Caco-2_PROLIF 176 bp overlap
ChIP liver ENCFF449HPV 326 bp overlap
HNRNPK 7 datasets
ChIP Hep-G2 ENCSR519QAA.HNRNPK.Hep-G2 323 bp overlap
ChIP Hep-G2 GSE120104.HNRNPK.Hep-G2 323 bp overlap
ChIP HepG2 ENCFF493GNS 439 bp overlap
ChIP HepG2 ENCFF493GNS 222 bp overlap
ChIP HepG2 ENCFF826MXP 432 bp overlap
ChIP HepG2 ENCFF826MXP 219 bp overlap
ChIP K-562 GSE120104.HNRNPK.K-562 184 bp overlap
HOXB13 4 datasets
ChIP prostate-cancer_PDX_141 GSE130408.HOXB13.prostate-cancer_PDX_141 185 bp overlap
ChIP prostate-cancer_PDX_70 GSE130408.HOXB13.prostate-cancer_PDX_70 143 bp overlap
ChIP prostate_2483_T GSE130408.HOXB13.prostate_2483_T 275 bp overlap
ChIP prostate_P29_T GSE130408.HOXB13.prostate_P29_T 189 bp overlap
IRF3 2 datasets
Motif DE_48h DE_48h-IRF3_MA1418.2 17 bp overlap
Motif DE_72h DE_72h-IRF3_MA1418.2 17 bp overlap
Irf1 3 datasets
Motif DE_12h DE_12h-Irf1_MA0050.4 11 bp overlap
Motif DE_48h DE_48h-Irf1_MA0050.4 11 bp overlap
Motif DE_72h DE_72h-Irf1_MA0050.4 11 bp overlap
JUN 3 datasets
ChIP DE_D1 S08-DE-d1-JUN-exp1 262 bp overlap
ChIP DE_D2 S54-DE-d2-JUN-exp2 367 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 300 bp overlap
KLF1 2 datasets
Motif DE_48h DE_48h-KLF1_MA0493.3 8 bp overlap
Motif DE_72h DE_72h-KLF1_MA0493.3 8 bp overlap
KLF10 2 datasets
Motif DE_48h DE_48h-KLF10_MA1511.2 9 bp overlap
Motif DE_72h DE_72h-KLF10_MA1511.2 9 bp overlap
KLF11 2 datasets
Motif DE_48h DE_48h-KLF11_MA1512.2 10 bp overlap
Motif DE_72h DE_72h-KLF11_MA1512.2 10 bp overlap
KLF14 2 datasets
Motif DE_48h DE_48h-KLF14_MA0740.2 9 bp overlap
Motif DE_72h DE_72h-KLF14_MA0740.2 9 bp overlap
KLF16 2 datasets
Motif DE_48h DE_48h-KLF16_MA0741.1 11 bp overlap
Motif DE_72h DE_72h-KLF16_MA0741.1 11 bp overlap
KLF17 1 dataset
Motif DE_72h DE_72h-KLF17_MA1514.2 14 bp overlap
KLF2 2 datasets
Motif DE_48h DE_48h-KLF2_MA1515.2 8 bp overlap
Motif DE_72h DE_72h-KLF2_MA1515.2 8 bp overlap
KLF4 2 datasets
Motif DE_48h DE_48h-KLF4_MA0039.5 8 bp overlap
Motif DE_72h DE_72h-KLF4_MA0039.5 8 bp overlap
KLF5 2 datasets
Motif DE_48h DE_48h-KLF5_MA0599.1 10 bp overlap
Motif DE_72h DE_72h-KLF5_MA0599.1 10 bp overlap
KLF9 2 datasets
Motif DE_48h DE_48h-KLF9_MA1107.3 11 bp overlap
Motif DE_72h DE_72h-KLF9_MA1107.3 11 bp overlap
KMT2A 1 dataset
ChIP L826 GSE83671.KMT2A.L826 103 bp overlap
MAFG::NFE2L1 3 datasets
Motif DE_12h DE_12h-MAFGNFE2L1_MA0089.3 11 bp overlap
Motif DE_48h DE_48h-MAFGNFE2L1_MA0089.3 11 bp overlap
Motif DE_72h DE_72h-MAFGNFE2L1_MA0089.3 11 bp overlap
MEIS1 3 datasets
Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap
Motif DE_48h DE_48h-MEIS1_MA0498.3 5 bp overlap
Motif DE_72h DE_72h-MEIS1_MA0498.3 5 bp overlap
MSANTD3 1 dataset
Motif DE_72h DE_72h-MSANTD3_MA1523.2 7 bp overlap
MYCN 1 dataset
ChIP RH4 GSE83726.MYCN.RH4 316 bp overlap
NANOG 4 datasets
ChIP HUES-8 GSE109524.NANOG.HUES-8 571 bp overlap
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 571 bp overlap
ChIP WA09 GSE105028.NANOG.WA09 267 bp overlap
ChIP hESC GSE18292.NANOG.hESC 199 bp overlap
NEUROD1 2 datasets
Motif DE_60h DE_60h-NEUROD1_MA1109.2 8 bp overlap
Motif DE_72h DE_72h-NEUROD1_MA1109.2 8 bp overlap
NEUROG2 2 datasets
Motif DE_60h DE_60h-NEUROG2_MA1642.2 7 bp overlap
Motif DE_72h DE_72h-NEUROG2_MA1642.2 7 bp overlap
NKX2-2 1 dataset
Motif DE_72h DE_72h-NKX2-2_MA1645.2 8 bp overlap
NR1D2 1 dataset
Motif DE_72h DE_72h-NR1D2_MA1532.2 15 bp overlap
NR4A1 2 datasets
Motif DE_60h DE_60h-NR4A1_MA1112.3 8 bp overlap
Motif DE_72h DE_72h-NR4A1_MA1112.3 8 bp overlap
Neurod2 2 datasets
Motif DE_60h DE_60h-Neurod2_MA0668.3 8 bp overlap
Motif DE_72h DE_72h-Neurod2_MA0668.3 8 bp overlap
Nr2e1 2 datasets
Motif DE_60h DE_60h-Nr2e1_MA0676.1 9 bp overlap
Motif DE_72h DE_72h-Nr2e1_MA0676.1 9 bp overlap
PATZ1 2 datasets
Motif DE_48h DE_48h-PATZ1_MA1961.2 11 bp overlap
Motif DE_72h DE_72h-PATZ1_MA1961.2 11 bp overlap
PCBP2 1 dataset
ChIP Hep-G2 GSE120104.PCBP2.Hep-G2 204 bp overlap
PDX1 2 datasets
ChIP hiPSC GSE125768.PDX1.hiPSC 161 bp overlap
ChIP hiPSC_derived_PPs GSE106949.PDX1.hiPSC_derived_PPs 182 bp overlap
PGR 1 dataset
ChIP T-47D_PROG GSE68355.PGR.T-47D_PROG 205 bp overlap
PLAG1 1 dataset
Motif DE_72h DE_72h-PLAG1_MA0163.1 14 bp overlap
POU5F1 1 dataset
ChIP DE_D1 DED1-OCT4_Batch_II 490 bp overlap
POU5F1_M 1 dataset
ChIP DE_D1 DED1-OCT4-M_Batch_II 396 bp overlap
Ptf1A 2 datasets
Motif DE_60h DE_60h-Ptf1A_MA1618.2 9 bp overlap
Motif DE_72h DE_72h-Ptf1A_MA1618.2 9 bp overlap
RAD21 1 dataset
ChIP K562 ENCFF634XYR 139 bp overlap
RARA 2 datasets
ChIP hiPSC_D3 GSE109172.RARA.hiPSC_D3 464 bp overlap
ChIP hiPSC_D4 GSE109172.RARA.hiPSC_D4 503 bp overlap
RREB1 1 dataset
Motif DE_72h DE_72h-RREB1_MA0073.2 19 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 534 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 519 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 528 bp overlap
SMAD2_3 4 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 467 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 508 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 412 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 370 bp overlap
SMAD4 1 dataset
ChIP Caco-2 GSE112946.SMAD4.Caco-2 112 bp overlap
SMARCA4 1 dataset
ChIP hiPSC GSE124903.SMARCA4.hiPSC 571 bp overlap
SMARCB1 1 dataset
ChIP hiPSC GSE124903.SMARCB1.hiPSC 571 bp overlap
SMARCC1 3 datasets
ChIP DE_D1 S10-DE-d1-BAF155-exp1 262 bp overlap
ChIP DE_D1 S15-DE-d1-BAF155-exp1 345 bp overlap
ChIP hiPSC GSE124903.SMARCC1.hiPSC 571 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 263 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 571 bp overlap
SOX2 1 dataset
ChIP HNSC GSE69479.SOX2.HNSC 193 bp overlap
SOX21 3 datasets
Motif DE_12h DE_12h-SOX21_MA0866.1 15 bp overlap
Motif DE_48h DE_48h-SOX21_MA0866.1 15 bp overlap
Motif DE_72h DE_72h-SOX21_MA0866.1 15 bp overlap
SP1 1 dataset
ChIP liver ENCFF769YSM 379 bp overlap
SP3 2 datasets
Motif DE_48h DE_48h-SP3_MA0746.3 11 bp overlap
Motif DE_72h DE_72h-SP3_MA0746.3 11 bp overlap
STAT1::STAT2 2 datasets
Motif DE_48h DE_48h-STAT1STAT2_MA0517.2 13 bp overlap
Motif DE_72h DE_72h-STAT1STAT2_MA0517.2 13 bp overlap
STAT3 6 datasets
ChIP T-47D_JC4751 GSE126004.STAT3.T-47D_JC4751 239 bp overlap
ChIP T-47D_JC4753 GSE126004.STAT3.T-47D_JC4753 202 bp overlap
ChIP T-47D_JC4757 GSE126004.STAT3.T-47D_JC4757 187 bp overlap
ChIP T-47D_JC5054 GSE126004.STAT3.T-47D_JC5054 252 bp overlap
ChIP T-47D_JC5056 GSE126004.STAT3.T-47D_JC5056 216 bp overlap
ChIP T-47D_JC5062 GSE126004.STAT3.T-47D_JC5062 192 bp overlap
Stat2 2 datasets
Motif DE_48h DE_48h-Stat2_MA1623.2 10 bp overlap
Motif DE_72h DE_72h-Stat2_MA1623.2 10 bp overlap
T 2 datasets
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 525 bp overlap
ChIP H9_MESODERM GSE60606.T.H9_MESODERM 532 bp overlap
TAL1::TCF3 2 datasets
Motif DE_60h DE_60h-TAL1TCF3_MA0091.2 10 bp overlap
Motif DE_72h DE_72h-TAL1TCF3_MA0091.2 10 bp overlap
TBX20 3 datasets
Motif DE_12h DE_12h-TBX20_MA0689.1 11 bp overlap
Motif DE_48h DE_48h-TBX20_MA0689.1 11 bp overlap
Motif DE_72h DE_72h-TBX20_MA0689.1 11 bp overlap
TEAD1 1 dataset
ChIP pancreas_12D ERP008682.TEAD1.pancreas_12D 185 bp overlap
TEAD4 2 datasets
ChIP SNU-216 GSE44416.TEAD4.SNU-216 90 bp overlap
ChIP T-47D_Veh GSE125594.TEAD4.T-47D_Veh 178 bp overlap
THRA 2 datasets
Motif DE_60h DE_60h-THRA_MA1969.2 18 bp overlap
Motif DE_72h DE_72h-THRA_MA1969.2 18 bp overlap
TP53 1 dataset
ChIP hESC_DAMAGED GSE39912.TP53.hESC_DAMAGED 212 bp overlap
TWIST1 2 datasets
Motif DE_60h DE_60h-TWIST1_MA1123.3 8 bp overlap
Motif DE_72h DE_72h-TWIST1_MA1123.3 8 bp overlap
VDR 1 dataset
ChIP kidney-cortex GSE129585.VDR.kidney-cortex 385 bp overlap
VEZF1 1 dataset
Motif DE_72h DE_72h-VEZF1_MA1578.2 6 bp overlap
Yy1 3 datasets
Motif DE_12h DE_12h-Yy1_MA0095.4 8 bp overlap
Motif DE_48h DE_48h-Yy1_MA0095.4 8 bp overlap
Motif DE_72h DE_72h-Yy1_MA0095.4 8 bp overlap
ZNF148 2 datasets
Motif DE_48h DE_48h-ZNF148_MA1653.2 10 bp overlap
Motif DE_72h DE_72h-ZNF148_MA1653.2 10 bp overlap
ZNF281 3 datasets
Motif DE_48h DE_48h-ZNF281_MA1630.3 10 bp overlap
Motif DE_72h DE_72h-ZNF281_MA1630.3 10 bp overlap
Motif DE_72h DE_72h-ZNF281_MA1630.3 10 bp overlap
ZNF677 2 datasets
Motif DE_48h DE_48h-ZNF677_MA2101.1 12 bp overlap
Motif DE_72h DE_72h-ZNF677_MA2101.1 12 bp overlap
ZNF684 2 datasets
Motif DE_60h DE_60h-ZNF684_MA1600.2 14 bp overlap
Motif DE_72h DE_72h-ZNF684_MA1600.2 14 bp overlap
ZNF740 1 dataset
Motif DE_72h DE_72h-ZNF740_MA0753.3 10 bp overlap
Zic1::Zic2 3 datasets
Motif DE_12h DE_12h-Zic1Zic2_MA1628.2 7 bp overlap
Motif DE_48h DE_48h-Zic1Zic2_MA1628.2 7 bp overlap
Motif DE_72h DE_72h-Zic1Zic2_MA1628.2 7 bp overlap
Zic2 3 datasets
Motif DE_12h DE_12h-Zic2_MA1629.2 9 bp overlap
Motif DE_48h DE_48h-Zic2_MA1629.2 9 bp overlap
Motif DE_72h DE_72h-Zic2_MA1629.2 9 bp overlap
Zic3 3 datasets
Motif DE_12h DE_12h-Zic3_MA0697.3 7 bp overlap
Motif DE_48h DE_48h-Zic3_MA0697.3 7 bp overlap
Motif DE_72h DE_72h-Zic3_MA0697.3 7 bp overlap
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