chr6:13,859,849–13,861,074

chr6 : 13,859,849 – 13,861,074

1,225 bp 81 TFs 6 linked genes

This 1.2 kb open chromatin element is linked to 6 target genes and is bound by 81 transcription factors.

Linked Genes

6 genes

Gene	Expression	Dist. to TSS	Distance	Link type
MCUR1		45.9 kb	Distal	Multiome
RNF182		64.5 kb	Distal	Multiome
RANBP9		148.6 kb	Distal	Multiome
NOL7		245.1 kb	Distal	Multiome
CD83		257.2 kb	Distal	Multiome
SIRT5		285.9 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

81 transcription factors

ChIP myofibroblast GSE90772.AR.myofibroblast 575 bp overlap

ChIP 501-mel GSE95280.ARNT.501-mel 304 bp overlap

ASH1L 1 dataset

ChIP K562 ENCFF808EMX 437 bp overlap

ChIP metastatic-neuroblastoma_SKNFI GSE100148.ATRX.metastatic-neuroblastoma_SKNFI 349 bp overlap

BRD4 7 datasets

ChIP CLL_patient2 GSE109411.BRD4.CLL_patient2 239 bp overlap

ChIP CLL_patient2_4h_CpG_BET GSE109411.BRD4.CLL_patient2_4h_CpG_BET 404 bp overlap

ChIP COLO-741 GSE73319.BRD4.COLO-741 479 bp overlap

ChIP MCF-10A ERP003925.BRD4.MCF-10A 564 bp overlap

ChIP hESC GSE33281.BRD4.hESC 85 bp overlap

ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 365 bp overlap

ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 450 bp overlap

CBFB 2 datasets

ChIP ME-1 GSE46044.CBFB.ME-1 237 bp overlap

ChIP ME-1 GSE46044.CBFB.ME-1 454 bp overlap

CEBPG 2 datasets

ChIP K562 ENCFF783ADE 80 bp overlap

ChIP K562 ENCFF956TPS 50 bp overlap

CHAMP1 2 datasets

ChIP K-562 ENCSR065XVO.CHAMP1.K-562 296 bp overlap

ChIP K562 ENCFF860ZIW 457 bp overlap

ChIP hMSC-TERT GSE89179.CHD1.hMSC-TERT 209 bp overlap

ChIP SK-N-SH ENCFF669KMB 361 bp overlap

CREB1 1 dataset

ChIP GM23338 ENCFF432ZEW 258 bp overlap

CTCF 18 datasets

ChIP 786-O_NORMOXIA GSE78113.CTCF.786-O_NORMOXIA 237 bp overlap

ChIP BE2C ENCSR000DQD.CTCF.BE2C 137 bp overlap

ChIP GM23338 ENCFF531QOI 425 bp overlap

ChIP GM23338 ENCFF772DML 201 bp overlap

ChIP Kelly_resistant GSE103030.CTCF.Kelly_resistant 122 bp overlap

ChIP Kelly_sensitive GSE103030.CTCF.Kelly_sensitive 131 bp overlap

ChIP NB69 GSE101295.CTCF.NB69 187 bp overlap

ChIP SH-SY5Y GSE101295.CTCF.SH-SY5Y 158 bp overlap

ChIP SK-N-SH ENCSR000DXQ.CTCF.SK-N-SH 159 bp overlap

ChIP anterior-temporal-cortex_fetal GSE116825.CTCF.anterior-temporal-cortex_fetal 329 bp overlap

ChIP hiPSC_CVI GSE106870.CTCF.hiPSC_CVI 204 bp overlap

ChIP hiPSC_IB12 GSE106870.CTCF.hiPSC_IB12 161 bp overlap

ChIP hiPSC_IB7 GSE106870.CTCF.hiPSC_IB7 263 bp overlap

ChIP hiPSC_IIIB12 GSE106870.CTCF.hiPSC_IIIB12 130 bp overlap

ChIP hiPSC_IV8 GSE106870.CTCF.hiPSC_IV8 258 bp overlap

ChIP hiPSC_failed-genome-editing GSE106870.CTCF.hiPSC_failed-genome-editing 153 bp overlap

ChIP neuron_bipolar_doxy_4d ENCSR619IUE.CTCF.neuron_bipolar_doxy_4d 131 bp overlap

ChIP primary-glioblastoma_G567 GSE121601.CTCF.primary-glioblastoma_G567 185 bp overlap

CTCFL 2 datasets

ChIP K-562 GSE70764.CTCFL.K-562 526 bp overlap

ChIP Kelly_resistant GSE103030.CTCFL.Kelly_resistant 109 bp overlap

CTNNB1 1 dataset

ChIP hiPSC_D2 GSE132532.CTNNB1.hiPSC_D2 581 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF274GAT 396 bp overlap

ChIP H1 ENCFF785DWK 451 bp overlap

EP300 1 dataset

ChIP osteoblast ENCSR000AUD.EP300.osteoblast 774 bp overlap

ChIP CD34_NR29 GSE23730.ERG.CD34_NR29 563 bp overlap

ChIP MCF-7 GSE23730.ERG.MCF-7 294 bp overlap

ChIP ME-1 GSE46044.ERG.ME-1 200 bp overlap

ESR1 4 datasets

ChIP Ishikawa GSE99905.ESR1.Ishikawa 428 bp overlap

ChIP Ishikawa_siNTC-72h GSE129803.ESR1.Ishikawa_siNTC-72h 208 bp overlap

ChIP Ishikawa_siNTC-96h GSE129803.ESR1.Ishikawa_siNTC-96h 230 bp overlap

ChIP MCF-7_PaPE-1_OA GSE93510.ESR1.MCF-7_PaPE-1_OA 359 bp overlap

ChIP WTC11 ENCFF812SCD 437 bp overlap

EZH2 9 datasets

ChIP astrocyte ENCFF365JTP 541 bp overlap

ChIP astrocyte ENCFF365JTP 742 bp overlap

ChIP astrocyte ENCSR000ARR.EZH2.astrocyte 197 bp overlap

ChIP astrocyte ENCSR000ARR.EZH2.astrocyte 299 bp overlap

ChIP endothelial_umbilical-vein ENCSR000ATA.EZH2.endothelial_umbilical-vein 235 bp overlap

ChIP endothelial_umbilical-vein ENCSR000ATA.EZH2.endothelial_umbilical-vein 328 bp overlap

ChIP fibroblast_DERMAL ENCSR000ASE.EZH2.fibroblast_DERMAL 608 bp overlap

ChIP mammary epithelial cell ENCFF224GAI 491 bp overlap

ChIP myotube ENCSR000ASZ.EZH2.myotube 236 bp overlap

EZH2_phosphoT487 1 dataset

ChIP neuron_bipolar_doxy_4d ENCSR886KKK.EZH2_phosphoT487.neuron_bipolar_doxy_4d 788 bp overlap

FIP1L1 1 dataset

ChIP K562 ENCFF363ZMN 430 bp overlap

FOXA2 2 datasets

ChIP BJ1-hTERT_FoxHnf1aCoExp GSE90454.FOXA2.BJ1-hTERT_FoxHnf1aCoExp 243 bp overlap

ChIP BJ1-hTERT_FoxHnf1aCoExp GSE90454.FOXA2.BJ1-hTERT_FoxHnf1aCoExp 498 bp overlap

FOXP1 1 dataset

ChIP WTC11 ENCFF338WGC 525 bp overlap

HEXIM1 1 dataset

ChIP HCT-116 GSE72622.HEXIM1.HCT-116 266 bp overlap

HIVEP1 1 dataset

ChIP Hep-G2 ENCSR697WMX.HIVEP1.Hep-G2 350 bp overlap

HNRNPK 2 datasets

ChIP K-562 GSE120104.HNRNPK.K-562 310 bp overlap

ChIP K-562 ENCSR014RCS.HNRNPK.K-562 198 bp overlap

ChIP SK-N-SH ENCFF921DIM 245 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 378 bp overlap

KDM1A 1 dataset

ChIP pancreatic-progenitor_PP2-KDM1A-inh GSE104840.KDM1A.pancreatic-progenitor_PP2-KDM1A-inh 317 bp overlap

KDM4A 3 datasets

ChIP hiPSC_IA12 GSE106870.KDM4A.hiPSC_IA12 473 bp overlap

ChIP hiPSC_IIA11 GSE106870.KDM4A.hiPSC_IIA11 527 bp overlap

ChIP hiPSC_IID12 GSE106870.KDM4A.hiPSC_IID12 382 bp overlap

KLF13 1 dataset

Motif DE_12h DE_12h-KLF13_MA0657.2 17 bp overlap

ChIP THP-1_monocytes GSE96800.MAF1.THP-1_monocytes 220 bp overlap

ChIP 501-mel_K243Q GSE137522.MITF.501-mel_K243Q 314 bp overlap

MYCN 3 datasets

ChIP COG-N-415 GSE138295.MYCN.COG-N-415 353 bp overlap

ChIP LA-N-5 GSE138295.MYCN.LA-N-5 679 bp overlap

ChIP NB-1643 GSE138295.MYCN.NB-1643 761 bp overlap

NANOG 2 datasets

ChIP WA01 ERP004238.NANOG.WA01 360 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 453 bp overlap

NCAPH2 1 dataset

ChIP HEK293 GSE97540.NCAPH2.HEK293 680 bp overlap

NFATC3 2 datasets

ChIP K-562 ENCSR051OUX.NFATC3.K-562 302 bp overlap

ChIP K562 ENCFF078EKB 322 bp overlap

NFYA 3 datasets

Motif DE_24h DE_24h-NFYA_MA0060.4 8 bp overlap

ChIP K-562 ENCSR000EGR.NFYA.K-562 86 bp overlap

ChIP K562 ENCFF732HOX 328 bp overlap

NFYB 10 datasets

ChIP GM12878 ENCFF474DNH 222 bp overlap

ChIP GM12878 ENCSR000DNM.NFYB.GM12878 138 bp overlap

ChIP HeLa-S3 ENCFF854TNJ 323 bp overlap

ChIP Hep-G2 ENCSR935GZV.NFYB.Hep-G2 187 bp overlap

ChIP HepG2 ENCFF174VYX 275 bp overlap

ChIP K-562 ENCSR000EGQ.NFYB.K-562 496 bp overlap

ChIP K-562 GSE26439.NFYB.K-562 170 bp overlap

ChIP K562 ENCFF709RXX 125 bp overlap

ChIP WTC11 ENCFF751ZTQ 117 bp overlap

ChIP WTC11 ENCFF751ZTQ 326 bp overlap

NFYC 3 datasets

Motif DE_24h DE_24h-NFYC_MA1644.2 7 bp overlap

ChIP Hep-G2 ENCSR569ARC.NFYC.Hep-G2 151 bp overlap

ChIP HepG2 ENCFF836FYP 353 bp overlap

NR2F2 1 dataset

ChIP MCF-7_Veh GSE132432.NR2F2.MCF-7_Veh 735 bp overlap

ChIP retina_Hu13 GSE137311.NRL.retina_Hu13 288 bp overlap

OGG1 4 datasets

ChIP HEK293 GSE89017.OGG1.HEK293 843 bp overlap

ChIP HEK293_15min GSE89017.OGG1.HEK293_15min 776 bp overlap

ChIP HEK293_30_min GSE89017.OGG1.HEK293_30_min 740 bp overlap

ChIP HEK293_60_min GSE89017.OGG1.HEK293_60_min 780 bp overlap

Motif DE_24h DE_24h-PBX1_MA0070.2 9 bp overlap

POLR2A 1 dataset

ChIP spleen ENCFF706IUS 368 bp overlap

POU5F1 2 datasets

ChIP DE_D1 DED1-OCT4_Batch_II 611 bp overlap

ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 444 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 632 bp overlap

PRDM14 1 dataset

ChIP NCCIT GSE71675.PRDM14.NCCIT 226 bp overlap

Prdm15 1 dataset

Motif DE_24h DE_24h-Prdm15_MA1616.2 11 bp overlap

RBM25 1 dataset

ChIP K562 ENCFF957ORK 210 bp overlap

Motif DE_12h DE_12h-REST_MA0138.3 20 bp overlap

RORC 2 datasets

ChIP HCC70 GSE126380.RORC.HCC70 777 bp overlap

ChIP HCC70_XY018 GSE126380.RORC.HCC70_XY018 771 bp overlap

RUNX1 3 datasets

ChIP AML_Blast GSE60130.RUNX1.AML_Blast 243 bp overlap

ChIP CD34 GSE64862.RUNX1.CD34 243 bp overlap

ChIP ME-1 GSE46044.RUNX1.ME-1 235 bp overlap

RUNX1T1 1 dataset

ChIP Kasumi-1 GSE102697.RUNX1T1.Kasumi-1 156 bp overlap

SALL3 1 dataset

ChIP hiPSC GSE104863.SALL3.hiPSC 224 bp overlap

SIN3A 1 dataset

ChIP hiPSC_IB12 GSE106870.SIN3A.hiPSC_IB12 244 bp overlap

SIRT6 1 dataset

ChIP SK-MEL-239_L-C-B GSE102813.SIRT6.SK-MEL-239_L-C-B 159 bp overlap

SMAD2_3 1 dataset

ChIP ESC S33-ESC-d0-SMAD2_3-exp2 264 bp overlap

SMARCA4 3 datasets

ChIP 22Rv1_PTEN-KO GSE115615.SMARCA4.22Rv1_PTEN-KO 207 bp overlap

ChIP 22Rv1_PTEN-KO GSE115615.SMARCA4.22Rv1_PTEN-KO 307 bp overlap

ChIP HS-SY-2_HA-tagged GSE108926.SMARCA4.HS-SY-2_HA-tagged 378 bp overlap

SMARCC1 2 datasets

ChIP DE_D1 S15-DE-d1-BAF155-exp1 538 bp overlap

ChIP ESC S25-ESC-d0-BAF155-exp1 594 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 585 bp overlap

SREBP2 2 datasets

ChIP HCC70 GSE126380.SREBP2.HCC70 759 bp overlap

ChIP HCC70_XY018 GSE126380.SREBP2.HCC70_XY018 633 bp overlap

STAT3 1 dataset

ChIP WA01 ERP004237.STAT3.WA01 559 bp overlap

SUZ12 2 datasets

ChIP CRL-7250_shSS18 GSE108025.SUZ12.CRL-7250_shSS18 687 bp overlap

ChIP CRL-7250_shSS18-SSX GSE108025.SUZ12.CRL-7250_shSS18-SSX 437 bp overlap

Smad4 2 datasets

Motif DE_24h DE_24h-Smad4_MA1153.2 7 bp overlap

Motif DE_24h DE_24h-Smad4_MA1153.2 7 bp overlap

TBL1X 1 dataset

ChIP HEK293T GSE35197.TBL1X.HEK293T 189 bp overlap

ChIP hiPSC_WTa_RNase-neg GSE128135.TBP.hiPSC_WTa_RNase-neg 251 bp overlap

TFAP2B 1 dataset

ChIP SK-N-SH ENCFF869XXQ 441 bp overlap

TFIIIC 1 dataset

ChIP HEK293 GSE119418.TFIIIC.HEK293 739 bp overlap

ChIP keratinocyte_diff GSE33571.TP63.keratinocyte_diff 164 bp overlap

TRIM25 2 datasets

ChIP BT-549 GSE79588.TRIM25.BT-549 342 bp overlap

ChIP BT-549 GSE79588.TRIM25.BT-549 290 bp overlap

TRIM28 3 datasets

ChIP AF22 GSE84259.TRIM28.AF22 467 bp overlap

ChIP HCT-116 GSE72622.TRIM28.HCT-116 232 bp overlap

ChIP hESC GSE115387.TRIM28.hESC 381 bp overlap

ChIP SMMC-7721 GSE126982.WDR5.SMMC-7721 731 bp overlap

ZBTB33 4 datasets

ChIP K-562 ENCSR876GXA.ZBTB33.K-562 924 bp overlap

ChIP K-562 ENCSR876GXA.ZBTB33.K-562 159 bp overlap

ChIP K562 ENCFF427SDV 505 bp overlap

ChIP K562 ENCFF875HLX 529 bp overlap

ZBTB6 1 dataset

Motif DE_24h DE_24h-ZBTB6_MA1581.2 9 bp overlap

ChIP SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour ENCSR581GUY.ZFP3.SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour 221 bp overlap

ZNF572 1 dataset

ChIP Hep-G2 ENCSR663CTC.ZNF572.Hep-G2 177 bp overlap

ZNF682 1 dataset

Motif DE_12h DE_12h-ZNF682_MA1599.2 11 bp overlap

ZNF768 1 dataset

ChIP HepG2 ENCFF388QCK 441 bp overlap