chr5 : 118,989,856 – 118,990,341
485 bp 94 TFs 1 linked gene
This 485 bp open chromatin element is linked to DTWD2 and is bound by 94 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
DTWD2 1.6 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr5:118,984,856 – 118,995,341
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
94 transcription factors
Source
Cell type
ALX3 3 datasets
Motif DE_48h DE_48h-ALX3_MA0634.2 6 bp overlap
Motif DE_60h DE_60h-ALX3_MA0634.2 6 bp overlap
Motif DE_72h DE_72h-ALX3_MA0634.2 6 bp overlap
ARID1A 1 dataset
ChIP 12Z GSE129781.ARID1A.12Z 132 bp overlap
ARID1B 2 datasets
ChIP K-562 ENCSR822CCM.ARID1B.K-562 332 bp overlap
ChIP K562 ENCFF938UXQ 395 bp overlap
ARID3A 1 dataset
ChIP K-562 ENCSR000EFY.ARID3A.K-562 210 bp overlap
BARX2 3 datasets
Motif DE_48h DE_48h-BARX2_MA1471.2 9 bp overlap
Motif DE_60h DE_60h-BARX2_MA1471.2 9 bp overlap
Motif DE_72h DE_72h-BARX2_MA1471.2 9 bp overlap
BRD3 1 dataset
ChIP K-562_DMSO GSE138084.BRD3.K-562_DMSO 328 bp overlap
CBFA2T3 2 datasets
ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 221 bp overlap
ChIP K562 ENCFF673OEZ 289 bp overlap
CEBPD 1 dataset
ChIP K-562 ENCSR000BVY.CEBPD.K-562 115 bp overlap
DPF2 1 dataset
ChIP K-562 ENCSR219BXP.DPF2.K-562 339 bp overlap
DRGX 3 datasets
Motif DE_48h DE_48h-DRGX_MA1481.2 6 bp overlap
Motif DE_60h DE_60h-DRGX_MA1481.2 6 bp overlap
Motif DE_72h DE_72h-DRGX_MA1481.2 6 bp overlap
EBF1 3 datasets
ChIP GM12878 ENCFF167CZS 239 bp overlap
ChIP LCL GSE75503.EBF1.LCL 105 bp overlap
ChIP MUTUL GSE75503.EBF1.MUTUL 250 bp overlap
EBF3 3 datasets
Motif DE_48h DE_48h-EBF3_MA1637.2 9 bp overlap
Motif DE_60h DE_60h-EBF3_MA1637.2 9 bp overlap
Motif DE_72h DE_72h-EBF3_MA1637.2 9 bp overlap
EMX1 3 datasets
Motif DE_48h DE_48h-EMX1_MA0612.3 6 bp overlap
Motif DE_60h DE_60h-EMX1_MA0612.3 6 bp overlap
Motif DE_72h DE_72h-EMX1_MA0612.3 6 bp overlap
EMX2 3 datasets
Motif DE_48h DE_48h-EMX2_MA0886.2 6 bp overlap
Motif DE_60h DE_60h-EMX2_MA0886.2 6 bp overlap
Motif DE_72h DE_72h-EMX2_MA0886.2 6 bp overlap
EN1 3 datasets
Motif DE_48h DE_48h-EN1_MA0027.3 6 bp overlap
Motif DE_60h DE_60h-EN1_MA0027.3 6 bp overlap
Motif DE_72h DE_72h-EN1_MA0027.3 6 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 187 bp overlap
EP300 1 dataset
ChIP K-562 ENCSR000EGE.EP300.K-562 159 bp overlap
EVX1 3 datasets
Motif DE_48h DE_48h-EVX1_MA0887.2 6 bp overlap
Motif DE_60h DE_60h-EVX1_MA0887.2 6 bp overlap
Motif DE_72h DE_72h-EVX1_MA0887.2 6 bp overlap
EVX2 3 datasets
Motif DE_48h DE_48h-EVX2_MA0888.2 6 bp overlap
Motif DE_60h DE_60h-EVX2_MA0888.2 6 bp overlap
Motif DE_72h DE_72h-EVX2_MA0888.2 6 bp overlap
Ebf2 3 datasets
Motif DE_48h DE_48h-Ebf2_MA1604.2 9 bp overlap
Motif DE_60h DE_60h-Ebf2_MA1604.2 9 bp overlap
Motif DE_72h DE_72h-Ebf2_MA1604.2 9 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 330 bp overlap
ChIP DE DE-FOXA2-2 325 bp overlap
GATA1 4 datasets
ChIP K-562 GSE107726.GATA1.K-562 249 bp overlap
ChIP K-562_dCas9-LSD1 GSE132212.GATA1.K-562_dCas9-LSD1 198 bp overlap
ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 179 bp overlap
ChIP erythroblast ENCSR000EXP.GATA1.erythroblast 377 bp overlap
GATA2 2 datasets
ChIP K-562 ENCSR000DKA.GATA2.K-562 299 bp overlap
ChIP dermal-fibroblast_alone GSE51025.GATA2.dermal-fibroblast_alone 228 bp overlap
GATA4 6 datasets
ChIP DE DE-GATA4-1 426 bp overlap
ChIP DE DE-GATA4-2 485 bp overlap
ChIP Hep-G2 GSE135714.GATA4.Hep-G2 232 bp overlap
ChIP foregut GSE117136.GATA4.foregut 326 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 314 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 297 bp overlap
GATA6 15 datasets
ChIP AGS GSE51705.GATA6.AGS 238 bp overlap
ChIP DE DE-GATA6-1 372 bp overlap
ChIP DE DE-GATA6-2 440 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 428 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 336 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 279 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 459 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 351 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 400 bp overlap
ChIP YCC-3 GSE51705.GATA6.YCC-3 185 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 286 bp overlap
ChIP foregut GSE117136.GATA6.foregut 377 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 325 bp overlap
ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 326 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 343 bp overlap
GSX1 3 datasets
Motif DE_48h DE_48h-GSX1_MA0892.2 6 bp overlap
Motif DE_60h DE_60h-GSX1_MA0892.2 6 bp overlap
Motif DE_72h DE_72h-GSX1_MA0892.2 6 bp overlap
GSX2 3 datasets
Motif DE_48h DE_48h-GSX2_MA0893.3 7 bp overlap
Motif DE_60h DE_60h-GSX2_MA0893.3 7 bp overlap
Motif DE_72h DE_72h-GSX2_MA0893.3 7 bp overlap
HDAC2 1 dataset
ChIP pre-B-cell GSE107886.HDAC2.pre-B-cell 204 bp overlap
HNF1A 3 datasets
Motif DE_48h DE_48h-HNF1A_MA0046.3 13 bp overlap
Motif DE_60h DE_60h-HNF1A_MA0046.3 13 bp overlap
Motif DE_72h DE_72h-HNF1A_MA0046.3 13 bp overlap
HNF1B 3 datasets
Motif DE_48h DE_48h-HNF1B_MA0153.2 13 bp overlap
Motif DE_60h DE_60h-HNF1B_MA0153.2 13 bp overlap
Motif DE_72h DE_72h-HNF1B_MA0153.2 13 bp overlap
HOXA1 3 datasets
Motif DE_48h DE_48h-HOXA1_MA1495.2 6 bp overlap
Motif DE_60h DE_60h-HOXA1_MA1495.2 6 bp overlap
Motif DE_72h DE_72h-HOXA1_MA1495.2 6 bp overlap
HOXA2 3 datasets
Motif DE_48h DE_48h-HOXA2_MA0900.3 6 bp overlap
Motif DE_60h DE_60h-HOXA2_MA0900.3 6 bp overlap
Motif DE_72h DE_72h-HOXA2_MA0900.3 6 bp overlap
HOXA3 3 datasets
Motif DE_48h DE_48h-HOXA3_MA2119.1 7 bp overlap
Motif DE_60h DE_60h-HOXA3_MA2119.1 7 bp overlap
Motif DE_72h DE_72h-HOXA3_MA2119.1 7 bp overlap
HOXA6 3 datasets
Motif DE_48h DE_48h-HOXA6_MA1497.2 7 bp overlap
Motif DE_60h DE_60h-HOXA6_MA1497.2 7 bp overlap
Motif DE_72h DE_72h-HOXA6_MA1497.2 7 bp overlap
HOXB1 3 datasets
Motif DE_48h DE_48h-HOXB1_MA2093.1 7 bp overlap
Motif DE_60h DE_60h-HOXB1_MA2093.1 7 bp overlap
Motif DE_72h DE_72h-HOXB1_MA2093.1 7 bp overlap
HOXB2 3 datasets
Motif DE_48h DE_48h-HOXB2_MA0902.3 6 bp overlap
Motif DE_60h DE_60h-HOXB2_MA0902.3 6 bp overlap
Motif DE_72h DE_72h-HOXB2_MA0902.3 6 bp overlap
HOXB3 3 datasets
Motif DE_48h DE_48h-HOXB3_MA0903.2 6 bp overlap
Motif DE_60h DE_60h-HOXB3_MA0903.2 6 bp overlap
Motif DE_72h DE_72h-HOXB3_MA0903.2 6 bp overlap
HOXB5 3 datasets
Motif DE_48h DE_48h-HOXB5_MA0904.3 6 bp overlap
Motif DE_60h DE_60h-HOXB5_MA0904.3 6 bp overlap
Motif DE_72h DE_72h-HOXB5_MA0904.3 6 bp overlap
HOXB6 3 datasets
Motif DE_48h DE_48h-HOXB6_MA1500.2 7 bp overlap
Motif DE_60h DE_60h-HOXB6_MA1500.2 7 bp overlap
Motif DE_72h DE_72h-HOXB6_MA1500.2 7 bp overlap
HOXB7 3 datasets
Motif DE_48h DE_48h-HOXB7_MA1501.2 7 bp overlap
Motif DE_60h DE_60h-HOXB7_MA1501.2 7 bp overlap
Motif DE_72h DE_72h-HOXB7_MA1501.2 7 bp overlap
HOXB8 3 datasets
Motif DE_48h DE_48h-HOXB8_MA1502.2 7 bp overlap
Motif DE_60h DE_60h-HOXB8_MA1502.2 7 bp overlap
Motif DE_72h DE_72h-HOXB8_MA1502.2 7 bp overlap
HOXC8 3 datasets
Motif DE_48h DE_48h-HOXC8_MA1505.2 6 bp overlap
Motif DE_60h DE_60h-HOXC8_MA1505.2 6 bp overlap
Motif DE_72h DE_72h-HOXC8_MA1505.2 6 bp overlap
HOXD8 3 datasets
Motif DE_48h DE_48h-HOXD8_MA0910.3 7 bp overlap
Motif DE_60h DE_60h-HOXD8_MA0910.3 7 bp overlap
Motif DE_72h DE_72h-HOXD8_MA0910.3 7 bp overlap
IKZF1 3 datasets
ChIP K-562 ENCSR395HWC.IKZF1.K-562 273 bp overlap
ChIP K562 ENCFF348IBL 322 bp overlap
ChIP pre-B-cell GSE107886.IKZF1.pre-B-cell 247 bp overlap
ISX 3 datasets
Motif DE_48h DE_48h-ISX_MA0654.2 6 bp overlap
Motif DE_60h DE_60h-ISX_MA0654.2 6 bp overlap
Motif DE_72h DE_72h-ISX_MA0654.2 6 bp overlap
JUN 1 dataset
ChIP DE_D2 S02-DE-d2-JUN-exp1 382 bp overlap
JUND 2 datasets
ChIP K-562 ENCSR000EGN.JUND.K-562 193 bp overlap
ChIP K562 ENCFF336RCR 461 bp overlap
KDM1A 2 datasets
ChIP K562 ENCFF934ZRG 239 bp overlap
ChIP K562 ENCFF934ZRG 442 bp overlap
L3MBTL2 2 datasets
ChIP K-562 ENCSR530XQI.L3MBTL2.K-562 342 bp overlap
ChIP K562 ENCFF320EQC 485 bp overlap
LHX5 3 datasets
Motif DE_48h DE_48h-LHX5_MA1519.2 7 bp overlap
Motif DE_60h DE_60h-LHX5_MA1519.2 7 bp overlap
Motif DE_72h DE_72h-LHX5_MA1519.2 7 bp overlap
Lhx3 3 datasets
Motif DE_48h DE_48h-Lhx3_MA0135.2 12 bp overlap
Motif DE_60h DE_60h-Lhx3_MA0135.2 12 bp overlap
Motif DE_72h DE_72h-Lhx3_MA0135.2 12 bp overlap
Lhx4 3 datasets
Motif DE_48h DE_48h-Lhx4_MA0704.2 6 bp overlap
Motif DE_60h DE_60h-Lhx4_MA0704.2 6 bp overlap
Motif DE_72h DE_72h-Lhx4_MA0704.2 6 bp overlap
Lhx8 3 datasets
Motif DE_48h DE_48h-Lhx8_MA0705.2 6 bp overlap
Motif DE_60h DE_60h-Lhx8_MA0705.2 6 bp overlap
Motif DE_72h DE_72h-Lhx8_MA0705.2 6 bp overlap
MAZ 1 dataset
ChIP K562 ENCFF809XHP 343 bp overlap
MEIS1 1 dataset
ChIP CHRF28811 ERR063469.MEIS1.CHRF28811 211 bp overlap
MEIS2 1 dataset
ChIP K-562 ENCSR851BNE.MEIS2.K-562 333 bp overlap
MEOX1 3 datasets
Motif DE_48h DE_48h-MEOX1_MA0661.2 7 bp overlap
Motif DE_60h DE_60h-MEOX1_MA0661.2 7 bp overlap
Motif DE_72h DE_72h-MEOX1_MA0661.2 7 bp overlap
MEOX2 3 datasets
Motif DE_48h DE_48h-MEOX2_MA0706.2 7 bp overlap
Motif DE_60h DE_60h-MEOX2_MA0706.2 7 bp overlap
Motif DE_72h DE_72h-MEOX2_MA0706.2 7 bp overlap
MIXL1 3 datasets
Motif DE_48h DE_48h-MIXL1_MA0662.2 6 bp overlap
Motif DE_60h DE_60h-MIXL1_MA0662.2 6 bp overlap
Motif DE_72h DE_72h-MIXL1_MA0662.2 6 bp overlap
MNX1 3 datasets
Motif DE_48h DE_48h-MNX1_MA0707.3 6 bp overlap
Motif DE_60h DE_60h-MNX1_MA0707.3 6 bp overlap
Motif DE_72h DE_72h-MNX1_MA0707.3 6 bp overlap
MYC 1 dataset
ChIP K-562 ENCSR000EGJ.MYC.K-562 130 bp overlap
NFE2 1 dataset
ChIP K-562 ENCSR000FCC.NFE2.K-562 116 bp overlap
NKX6-2 3 datasets
Motif DE_48h DE_48h-NKX6-2_MA0675.2 6 bp overlap
Motif DE_60h DE_60h-NKX6-2_MA0675.2 6 bp overlap
Motif DE_72h DE_72h-NKX6-2_MA0675.2 6 bp overlap
PAX3 3 datasets
Motif DE_48h DE_48h-PAX3_MA0780.1 10 bp overlap
Motif DE_60h DE_60h-PAX3_MA0780.1 10 bp overlap
Motif DE_72h DE_72h-PAX3_MA0780.1 10 bp overlap
PDX1 3 datasets
Motif DE_48h DE_48h-PDX1_MA0132.3 6 bp overlap
Motif DE_60h DE_60h-PDX1_MA0132.3 6 bp overlap
Motif DE_72h DE_72h-PDX1_MA0132.3 6 bp overlap
PKNOX1 1 dataset
ChIP K-562 ENCSR115SMW.PKNOX1.K-562 319 bp overlap
POU5F1 1 dataset
ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 91 bp overlap
POU6F1 3 datasets
Motif DE_48h DE_48h-POU6F1_MA0628.2 6 bp overlap
Motif DE_60h DE_60h-POU6F1_MA0628.2 6 bp overlap
Motif DE_72h DE_72h-POU6F1_MA0628.2 6 bp overlap
POU6F2 3 datasets
Motif DE_48h DE_48h-POU6F2_MA0793.2 9 bp overlap
Motif DE_60h DE_60h-POU6F2_MA0793.2 9 bp overlap
Motif DE_72h DE_72h-POU6F2_MA0793.2 9 bp overlap
PRRX1 3 datasets
Motif DE_48h DE_48h-PRRX1_MA0716.2 6 bp overlap
Motif DE_60h DE_60h-PRRX1_MA0716.2 6 bp overlap
Motif DE_72h DE_72h-PRRX1_MA0716.2 6 bp overlap
PSIP1 1 dataset
ChIP T-REx-293 GSE117155.PSIP1.T-REx-293 51 bp overlap
Pax7 3 datasets
Motif DE_48h DE_48h-Pax7_MA0680.3 10 bp overlap
Motif DE_60h DE_60h-Pax7_MA0680.3 10 bp overlap
Motif DE_72h DE_72h-Pax7_MA0680.3 10 bp overlap
RAX2 3 datasets
Motif DE_48h DE_48h-RAX2_MA0717.2 6 bp overlap
Motif DE_60h DE_60h-RAX2_MA0717.2 6 bp overlap
Motif DE_72h DE_72h-RAX2_MA0717.2 6 bp overlap
RORA 3 datasets
Motif DE_48h DE_48h-RORA_MA0072.2 11 bp overlap
Motif DE_60h DE_60h-RORA_MA0072.2 11 bp overlap
Motif DE_72h DE_72h-RORA_MA0072.2 11 bp overlap
SHOX 3 datasets
Motif DE_48h DE_48h-SHOX_MA0630.2 6 bp overlap
Motif DE_60h DE_60h-SHOX_MA0630.2 6 bp overlap
Motif DE_72h DE_72h-SHOX_MA0630.2 6 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 303 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 388 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 277 bp overlap
SMAD2_3 4 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 274 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 445 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 413 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 409 bp overlap
SMAD4 1 dataset
ChIP K562 ENCFF628RBP 352 bp overlap
SMARCA4 1 dataset
ChIP K-562 ENCSR587OQL.SMARCA4.K-562 354 bp overlap
SMARCE1 1 dataset
ChIP K-562 ENCSR157TCS.SMARCE1.K-562 259 bp overlap
Shox2 3 datasets
Motif DE_48h DE_48h-Shox2_MA0720.2 6 bp overlap
Motif DE_60h DE_60h-Shox2_MA0720.2 6 bp overlap
Motif DE_72h DE_72h-Shox2_MA0720.2 6 bp overlap
TAL1 2 datasets
ChIP K-562 ENCSR000EHB.TAL1.K-562 116 bp overlap
ChIP K562 ENCFF661CCK 277 bp overlap
TEAD4 1 dataset
ChIP K562 ENCFF673NIK 115 bp overlap
TLX2 3 datasets
Motif DE_48h DE_48h-TLX2_MA1577.2 6 bp overlap
Motif DE_60h DE_60h-TLX2_MA1577.2 6 bp overlap
Motif DE_72h DE_72h-TLX2_MA1577.2 6 bp overlap
UNCX 3 datasets
Motif DE_48h DE_48h-UNCX_MA0721.2 6 bp overlap
Motif DE_60h DE_60h-UNCX_MA0721.2 6 bp overlap
Motif DE_72h DE_72h-UNCX_MA0721.2 6 bp overlap
VAX2 3 datasets
Motif DE_48h DE_48h-VAX2_MA0723.3 6 bp overlap
Motif DE_60h DE_60h-VAX2_MA0723.3 6 bp overlap
Motif DE_72h DE_72h-VAX2_MA0723.3 6 bp overlap
YY1 1 dataset
ChIP Hep-G2_RBM25-KD GSE120104.YY1.Hep-G2_RBM25-KD 416 bp overlap
ZBTB6 3 datasets
Motif DE_48h DE_48h-ZBTB6_MA1581.2 9 bp overlap
Motif DE_60h DE_60h-ZBTB6_MA1581.2 9 bp overlap
Motif DE_72h DE_72h-ZBTB6_MA1581.2 9 bp overlap
ZEB2 2 datasets
ChIP K-562 ENCSR322CFO.ZEB2.K-562 193 bp overlap
ChIP K562 ENCFF975RXS 352 bp overlap
ZNF335 1 dataset
ChIP HEK293 ENCSR328SUD.ZNF335.HEK293 485 bp overlap
ZNF384 2 datasets
ChIP K-562 ENCSR000EFP.ZNF384.K-562 259 bp overlap
ChIP K562 ENCFF365NXQ 280 bp overlap
ZNF652 3 datasets
Motif DE_48h DE_48h-ZNF652_MA1657.2 9 bp overlap
Motif DE_60h DE_60h-ZNF652_MA1657.2 9 bp overlap
Motif DE_72h DE_72h-ZNF652_MA1657.2 9 bp overlap
ZXDB 1 dataset
ChIP HEK293 ENCSR559IOZ.ZXDB.HEK293 342 bp overlap
mix-a 3 datasets
Motif DE_48h DE_48h-mix-a_MA0621.2 7 bp overlap
Motif DE_60h DE_60h-mix-a_MA0621.2 7 bp overlap
Motif DE_72h DE_72h-mix-a_MA0621.2 7 bp overlap
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