chr3 : 171,370,865 – 171,371,724
859 bp 98 TFs 1 linked gene
This 859 bp open chromatin element is linked to TNIK and is bound by 98 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
TNIK 89.2 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr3:171,365,865 – 171,376,724
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
98 transcription factors
Source
Cell type
BCL6B 1 dataset
Motif DE_48h DE_48h-BCL6B_MA0731.1 17 bp overlap
BHLHE22 2 datasets
Motif DE_48h DE_48h-BHLHE22_MA1635.2 6 bp overlap
Motif DE_48h DE_48h-BHLHE22_MA1635.2 6 bp overlap
BHLHE23 2 datasets
Motif DE_48h DE_48h-BHLHE23_MA0817.2 10 bp overlap
Motif DE_72h DE_72h-BHLHE23_MA0817.2 10 bp overlap
BRD2 1 dataset
ChIP HCC1806_NTsiRNA GSE116879.BRD2.HCC1806_NTsiRNA 262 bp overlap
Bhlha15 2 datasets
Motif DE_48h DE_48h-Bhlha15_MA1472.3 8 bp overlap
Motif DE_48h DE_48h-Bhlha15_MA1472.3 8 bp overlap
CBFB 1 dataset
ChIP GM12878 ENCSR860UHK.CBFB.GM12878 170 bp overlap
CEBPA 1 dataset
Motif DE_72h DE_72h-CEBPA_MA0102.5 10 bp overlap
CEBPD 1 dataset
Motif DE_72h DE_72h-CEBPD_MA0836.3 8 bp overlap
CHD4 1 dataset
ChIP SCMC GSE155861.CHD4.SCMC 209 bp overlap
CREBBP 1 dataset
ChIP MCF-7 ERP000901.CREBBP.MCF-7 149 bp overlap
EED 1 dataset
ChIP GM12878 ENCFF266FYW 409 bp overlap
ELF1 2 datasets
ChIP Hep-G2 ENCSR000BMZ.ELF1.Hep-G2 112 bp overlap
ChIP K-562 ENCSR000BMD.ELF1.K-562 117 bp overlap
EOMES 2 datasets
Motif DE_72h DE_72h-EOMES_MA0800.2 9 bp overlap
ChIP hESC GSE26097.EOMES.hESC 436 bp overlap
ESR1 2 datasets
ChIP MCF-7_RUNX2_DOX GSE86538.ESR1.MCF-7_RUNX2_DOX 345 bp overlap
ChIP MDA-MB-134-VI_ESTROGEN GSE51022.ESR1.MDA-MB-134-VI_ESTROGEN 291 bp overlap
FERD3L 1 dataset
Motif DE_48h DE_48h-FERD3L_MA1485.1 14 bp overlap
FOXA1 2 datasets
ChIP CFPAC-1 GSE119930.FOXA1.CFPAC-1 359 bp overlap
ChIP CFPAC-1_FOXA2-KO GSE119930.FOXA1.CFPAC-1_FOXA2-KO 288 bp overlap
FOXA2 6 datasets
ChIP CFPAC-1_EV GSE119930.FOXA2.CFPAC-1_EV 416 bp overlap
ChIP CFPAC-1_HNF1B-KO GSE119930.FOXA2.CFPAC-1_HNF1B-KO 304 bp overlap
ChIP CFPAC-1_HOXB8-OE GSE119930.FOXA2.CFPAC-1_HOXB8-OE 365 bp overlap
ChIP DE DE-FOXA2-1 808 bp overlap
ChIP DE DE-FOXA2-2 859 bp overlap
ChIP PANC-1 GSE119930.FOXA2.PANC-1 325 bp overlap
GATA4 2 datasets
ChIP DE DE-GATA4-1 693 bp overlap
ChIP DE DE-GATA4-2 795 bp overlap
GATA6 9 datasets
ChIP DE DE-GATA6-1 585 bp overlap
ChIP DE DE-GATA6-2 778 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 508 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 653 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 696 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 727 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 724 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 682 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 600 bp overlap
GLIS1 1 dataset
ChIP HEK293 ENCSR482BBZ.GLIS1.HEK293 227 bp overlap
GRHL2 2 datasets
ChIP HBE GSE46194.GRHL2.HBE 261 bp overlap
ChIP OVCA429 GSE71018.GRHL2.OVCA429 155 bp overlap
HNF4A 2 datasets
Motif DE_60h DE_60h-HNF4A_MA0114.5 9 bp overlap
ChIP IM95 GSE114018.HNF4A.IM95 136 bp overlap
HNF4G 1 dataset
Motif DE_60h DE_60h-HNF4G_MA0484.3 9 bp overlap
HOXD10 1 dataset
Motif DE_72h DE_72h-HOXD10_MA1506.2 10 bp overlap
Hand1 3 datasets
Motif DE_48h DE_48h-Hand1_MA2123.1 9 bp overlap
Motif DE_60h DE_60h-Hand1_MA2123.1 9 bp overlap
Motif DE_72h DE_72h-Hand1_MA2123.1 9 bp overlap
IKZF1 3 datasets
ChIP GM12878 ENCFF753XDO 473 bp overlap
ChIP K-562 ENCSR395HWC.IKZF1.K-562 299 bp overlap
ChIP K562 ENCFF348IBL 410 bp overlap
IKZF2 2 datasets
ChIP GM12878 ENCFF918AID 482 bp overlap
ChIP GM12878 ENCSR680UQE.IKZF2.GM12878 236 bp overlap
ISL2 4 datasets
Motif DE_36h DE_36h-ISL2_MA0914.2 6 bp overlap
Motif DE_48h DE_48h-ISL2_MA0914.2 6 bp overlap
Motif DE_60h DE_60h-ISL2_MA0914.2 6 bp overlap
Motif DE_72h DE_72h-ISL2_MA0914.2 6 bp overlap
JUN 4 datasets
ChIP DE_D1 S08-DE-d1-JUN-exp1 613 bp overlap
ChIP DE_D1 S40-DE-d1-JUN-exp2 767 bp overlap
ChIP DE_D2 S02-DE-d2-JUN-exp1 698 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 741 bp overlap
KLF6 1 dataset
ChIP PDAC GSE64557.KLF6.PDAC 323 bp overlap
MED1 1 dataset
ChIP MM1-S_JQ1_5NM GSE49224.MED1.MM1-S_JQ1_5NM 196 bp overlap
MEIS1 3 datasets
Motif DE_48h DE_48h-MEIS1_MA0498.3 5 bp overlap
Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap
Motif DE_72h DE_72h-MEIS1_MA0498.3 5 bp overlap
MGA 1 dataset
Motif DE_72h DE_72h-MGA_MA0801.1 8 bp overlap
MGA::EVX1 1 dataset
Motif DE_72h DE_72h-MGAEVX1_MA1960.2 11 bp overlap
MSC 2 datasets
Motif DE_48h DE_48h-MSC_MA0665.1 10 bp overlap
Motif DE_48h DE_48h-MSC_MA0665.1 10 bp overlap
MYF5 2 datasets
Motif DE_48h DE_48h-MYF5_MA1641.2 8 bp overlap
Motif DE_48h DE_48h-MYF5_MA1641.2 8 bp overlap
MYOD1 1 dataset
ChIP rhabdomyosarcoma GSE50413.MYOD1.rhabdomyosarcoma 120 bp overlap
NCOR1 1 dataset
ChIP LS180 GSE39277.NCOR1.LS180 93 bp overlap
NEUROD1 5 datasets
ChIP D283-Med GSE92582.NEUROD1.D283-Med 389 bp overlap
ChIP D283-Med_shNEUROD1-1579 GSE92582.NEUROD1.D283-Med_shNEUROD1-1579 208 bp overlap
ChIP D341-Med_shGFP GSE92582.NEUROD1.D341-Med_shGFP 288 bp overlap
Motif DE_48h DE_48h-NEUROD1_MA1109.2 8 bp overlap
Motif DE_48h DE_48h-NEUROD1_MA1109.2 8 bp overlap
NEUROG2 1 dataset
ChIP MRC-5_N_1DPT GSE75910.NEUROG2.MRC-5_N_1DPT 189 bp overlap
NFIB 1 dataset
Motif DE_72h DE_72h-NFIB_MA1643.2 17 bp overlap
NHLH2 1 dataset
Motif DE_48h DE_48h-NHLH2_MA1529.2 16 bp overlap
NKX2-1 1 dataset
ChIP NCI-H3122 GSE39998.NKX2-1.NCI-H3122 175 bp overlap
Neurod2 4 datasets
Motif DE_48h DE_48h-Neurod2_MA0668.3 8 bp overlap
Motif DE_48h DE_48h-Neurod2_MA0668.3 8 bp overlap
Motif DE_48h DE_48h-Neurod2_MA1993.2 6 bp overlap
Motif DE_48h DE_48h-Neurod2_MA1993.2 6 bp overlap
OLIG1 2 datasets
Motif DE_48h DE_48h-OLIG1_MA0826.1 10 bp overlap
Motif DE_72h DE_72h-OLIG1_MA0826.1 10 bp overlap
OLIG2 2 datasets
Motif DE_48h DE_48h-OLIG2_MA0678.1 10 bp overlap
Motif DE_72h DE_72h-OLIG2_MA0678.1 10 bp overlap
OLIG3 2 datasets
Motif DE_48h DE_48h-OLIG3_MA0827.1 10 bp overlap
Motif DE_72h DE_72h-OLIG3_MA0827.1 10 bp overlap
Olig2 2 datasets
Motif DE_48h DE_48h-Olig2_MA1997.2 6 bp overlap
Motif DE_48h DE_48h-Olig2_MA1997.2 6 bp overlap
PAF1 1 dataset
ChIP HCT-116_ab20662 GSE97527.PAF1.HCT-116_ab20662 208 bp overlap
PAX3 1 dataset
Motif DE_72h DE_72h-PAX3_MA0780.1 10 bp overlap
PGR 2 datasets
Motif DE_48h DE_48h-PGR_MA2327.1 9 bp overlap
Motif DE_72h DE_72h-PGR_MA2327.1 9 bp overlap
PHIP 4 datasets
ChIP HCT-116_MLL1-KO__ab833 GSE101646.PHIP.HCT-116_MLL1-KO__ab833 348 bp overlap
ChIP HCT-116_ab833 GSE101646.PHIP.HCT-116_ab833 222 bp overlap
ChIP HCT-116_ab833 GSE101646.PHIP.HCT-116_ab833 283 bp overlap
ChIP HCT-116_ab834 GSE101646.PHIP.HCT-116_ab834 180 bp overlap
PRDM1 1 dataset
Motif DE_48h DE_48h-PRDM1_MA0508.4 7 bp overlap
PROX1 1 dataset
ChIP SW480 GSE60390.PROX1.SW480 211 bp overlap
Pax7 1 dataset
Motif DE_72h DE_72h-Pax7_MA0680.3 10 bp overlap
Ptf1A 2 datasets
Motif DE_48h DE_48h-Ptf1A_MA1619.2 8 bp overlap
Motif DE_48h DE_48h-Ptf1A_MA1619.2 8 bp overlap
RELA 2 datasets
ChIP Detroit-562_LPS GSE91018.RELA.Detroit-562_LPS 229 bp overlap
ChIP Detroit-562_TNFa GSE91018.RELA.Detroit-562_TNFa 447 bp overlap
RELB 1 dataset
ChIP GM12878 ENCSR387QUV.RELB.GM12878 291 bp overlap
RUNX3 1 dataset
ChIP GM12878 ENCFF395WHA 113 bp overlap
Rarg 1 dataset
Motif DE_48h DE_48h-Rarg_MA0860.1 17 bp overlap
SMAD2 2 datasets
Motif DE_48h DE_48h-SMAD2_MA1964.2 6 bp overlap
Motif DE_72h DE_72h-SMAD2_MA1964.2 6 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 775 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 750 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 730 bp overlap
SMAD2_3 5 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 508 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 551 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 672 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 595 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 638 bp overlap
SMAD3 2 datasets
ChIP NCI-H441 GSE51509.SMAD3.NCI-H441 221 bp overlap
ChIP NCI-H441_SIITTF1 GSE51509.SMAD3.NCI-H441_SIITTF1 315 bp overlap
SMARCA4 1 dataset
ChIP hiPSC GSE124903.SMARCA4.hiPSC 539 bp overlap
SMARCB1 1 dataset
ChIP hiPSC GSE124903.SMARCB1.hiPSC 209 bp overlap
SMARCC1 3 datasets
ChIP DE_D1 S10-DE-d1-BAF155-exp1 449 bp overlap
ChIP DE_D1 S15-DE-d1-BAF155-exp1 674 bp overlap
ChIP hiPSC GSE124903.SMARCC1.hiPSC 157 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 441 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 447 bp overlap
STAT3 6 datasets
ChIP HCC70_EtOH GSE85579.STAT3.HCC70_EtOH 178 bp overlap
ChIP MCF-7_jc5838 GSE126004.STAT3.MCF-7_jc5838 277 bp overlap
ChIP NCI-H358 GSE79707.STAT3.NCI-H358 260 bp overlap
ChIP T-47D_JC4751 GSE126004.STAT3.T-47D_JC4751 194 bp overlap
ChIP T-47D_JC5054 GSE126004.STAT3.T-47D_JC5054 216 bp overlap
ChIP T-47D_JC5056 GSE126004.STAT3.T-47D_JC5056 259 bp overlap
SUPT5H 1 dataset
ChIP DLD-1_NELFCD-AID GSE144786.SUPT5H.DLD-1_NELFCD-AID 232 bp overlap
T 2 datasets
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 456 bp overlap
ChIP H9_MESODERM GSE60606.T.H9_MESODERM 273 bp overlap
TAL1::TCF3 2 datasets
Motif DE_48h DE_48h-TAL1TCF3_MA0091.2 10 bp overlap
Motif DE_48h DE_48h-TAL1TCF3_MA0091.2 10 bp overlap
TBR1 1 dataset
Motif DE_72h DE_72h-TBR1_MA0802.2 9 bp overlap
TBX1 1 dataset
Motif DE_72h DE_72h-TBX1_MA0805.1 8 bp overlap
TBX15 1 dataset
Motif DE_72h DE_72h-TBX15_MA0803.1 8 bp overlap
TBX18 1 dataset
Motif DE_72h DE_72h-TBX18_MA1565.2 9 bp overlap
TBX2 1 dataset
Motif DE_72h DE_72h-TBX2_MA0688.2 9 bp overlap
TBX20 1 dataset
Motif DE_72h DE_72h-TBX20_MA0689.1 11 bp overlap
TBX21 1 dataset
Motif DE_72h DE_72h-TBX21_MA0690.3 10 bp overlap
TBX3 1 dataset
Motif DE_72h DE_72h-TBX3_MA1566.3 9 bp overlap
TBX4 1 dataset
Motif DE_72h DE_72h-TBX4_MA0806.1 8 bp overlap
TBX5 1 dataset
Motif DE_72h DE_72h-TBX5_MA0807.1 8 bp overlap
TCF7L2 2 datasets
Motif DE_72h DE_72h-TCF7L2_MA0523.2 9 bp overlap
ChIP LNCaP GSE51621.TCF7L2.LNCaP 484 bp overlap
TFAP4 3 datasets
Motif DE_48h DE_48h-TFAP4_MA0691.1 10 bp overlap
Motif DE_48h DE_48h-TFAP4_MA0691.1 10 bp overlap
ChIP DLD-1 GSE46935.TFAP4.DLD-1 324 bp overlap
Tbx6 1 dataset
Motif DE_72h DE_72h-Tbx6_MA1567.3 9 bp overlap
Tcf12 2 datasets
Motif DE_48h DE_48h-Tcf12_MA0521.3 6 bp overlap
Motif DE_48h DE_48h-Tcf12_MA0521.3 6 bp overlap
Tcf21 2 datasets
Motif DE_48h DE_48h-Tcf21_MA0832.2 10 bp overlap
Motif DE_48h DE_48h-Tcf21_MA0832.2 10 bp overlap
Twist2 2 datasets
Motif DE_48h DE_48h-Twist2_MA0633.3 6 bp overlap
Motif DE_48h DE_48h-Twist2_MA0633.3 6 bp overlap
YY1AP1 1 dataset
ChIP PC-9_1DF GSE131687.YY1AP1.PC-9_1DF 299 bp overlap
ZBTB18 2 datasets
Motif DE_48h DE_48h-ZBTB18_MA0698.2 11 bp overlap
Motif DE_48h DE_48h-ZBTB18_MA0698.2 11 bp overlap
ZBTB26 1 dataset
ChIP HEK293 GSE76494.ZBTB26.HEK293 177 bp overlap
ZNF331 1 dataset
Motif DE_60h DE_60h-ZNF331_MA1726.2 10 bp overlap
ZNF528 3 datasets
Motif DE_48h DE_48h-ZNF528_MA1597.1 17 bp overlap
Motif DE_60h DE_60h-ZNF528_MA1597.1 17 bp overlap
Motif DE_72h DE_72h-ZNF528_MA1597.1 17 bp overlap
ZNF708 1 dataset
Motif DE_48h DE_48h-ZNF708_MA1730.2 9 bp overlap
ZNF768 1 dataset
Motif DE_48h DE_48h-ZNF768_MA1731.2 9 bp overlap
ZSCAN4 3 datasets
Motif DE_48h DE_48h-ZSCAN4_MA1155.1 15 bp overlap
Motif DE_60h DE_60h-ZSCAN4_MA1155.1 15 bp overlap
Motif DE_72h DE_72h-ZSCAN4_MA1155.1 15 bp overlap
Zic2 2 datasets
Motif DE_48h DE_48h-Zic2_MA1629.2 9 bp overlap
Motif DE_48h DE_48h-Zic2_MA1629.2 9 bp overlap
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