chr22:39,077,158–39,077,634

chr22 : 39,077,158 – 39,077,634

476 bp 66 TFs 11 linked genes

This 476 bp open chromatin element is linked to 11 target genes and is bound by 66 transcription factors.

Linked Genes

11 genes

Gene	Expression	Dist. to TSS	Distance	Link type
APOBEC3G		at TSS	At TSS	Proximity
APOBEC3F		36.4 kb	Distal	Multiome
APOBEC3D		56.2 kb	Distal	Multiome
APOBEC3C		63.0 kb	Distal	Multiome
CBX7		75.3 kb	Distal	Multiome
PDGFB		165.7 kb	Distal	Multiome
CBX6		205.1 kb	Distal	Multiome
RPL3		242.3 kb	Distal	Multiome
SYNGR1		272.7 kb	Distal	Multiome
DNAL4		283.1 kb	Distal	Multiome
SUN2		283.1 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

66 transcription factors

BORCS8-MEF2B,MEF2B 1 dataset

ChIP GM12878 ENCFF427QAI 54 bp overlap

BRD2 10 datasets

ChIP HCC1806_BAZ2BsiRNA GSE116879.BRD2.HCC1806_BAZ2BsiRNA 219 bp overlap

ChIP HCC1806_NTsiRNA GSE116879.BRD2.HCC1806_NTsiRNA 214 bp overlap

ChIP K-562_DMSO-IFNG GSE138084.BRD2.K-562_DMSO-IFNG 174 bp overlap

ChIP K-562_iBET-BD1-IFNG GSE138084.BRD2.K-562_iBET-BD1-IFNG 198 bp overlap

ChIP MV4-11_IBET151_500nM GSE120715.BRD2.MV4-11_IBET151_500nM 151 bp overlap

ChIP NCI-H23 GSE113714.BRD2.NCI-H23 205 bp overlap

ChIP THP-1_DMSO GSE138084.BRD2.THP-1_DMSO 324 bp overlap

ChIP THP-1_iBET GSE138084.BRD2.THP-1_iBET 255 bp overlap

ChIP THP-1_iBET-BD1 GSE138084.BRD2.THP-1_iBET-BD1 298 bp overlap

ChIP THP-1_iBET-BD2 GSE138084.BRD2.THP-1_iBET-BD2 270 bp overlap

BRD3 3 datasets

ChIP K-562_DMSO-IFNG GSE138084.BRD3.K-562_DMSO-IFNG 156 bp overlap

ChIP MV4-11_DMSO GSE120715.BRD3.MV4-11_DMSO 134 bp overlap

ChIP MV4-11_IBET151_50nM GSE120715.BRD3.MV4-11_IBET151_50nM 148 bp overlap

BRD4 15 datasets

ChIP CLL_patient1 GSE109411.BRD4.CLL_patient1 220 bp overlap

ChIP CLL_patient1_4h_CpG GSE109411.BRD4.CLL_patient1_4h_CpG 199 bp overlap

ChIP CLL_patient2 GSE109411.BRD4.CLL_patient2 198 bp overlap

ChIP CLL_patient3 GSE109411.BRD4.CLL_patient3 171 bp overlap

ChIP CLL_patient3_4h_CpG GSE109411.BRD4.CLL_patient3_4h_CpG 279 bp overlap

ChIP CLL_patient4 GSE109411.BRD4.CLL_patient4 231 bp overlap

ChIP K-562_DMSO-IFNG GSE138084.BRD4.K-562_DMSO-IFNG 158 bp overlap

ChIP K-562_iBET-BD2-IFNG GSE138084.BRD4.K-562_iBET-BD2-IFNG 222 bp overlap

ChIP K-562_iBET-IFNG GSE138084.BRD4.K-562_iBET-IFNG 185 bp overlap

ChIP KOPT-K1 GSE54379.BRD4.KOPT-K1 170 bp overlap

ChIP MM1-S_JQ1_50NM GSE42355.BRD4.MM1-S_JQ1_50NM 229 bp overlap

ChIP MM1-S_JQ1_5NM GSE42355.BRD4.MM1-S_JQ1_5NM 230 bp overlap

ChIP MV4-11_DMSO GSE120715.BRD4.MV4-11_DMSO 150 bp overlap

ChIP SEM GSE83671.BRD4.SEM 183 bp overlap

ChIP THP-1_iBET-BD2 GSE138084.BRD4.THP-1_iBET-BD2 204 bp overlap

CTBP1 2 datasets

ChIP K562 ENCFF403WPG 414 bp overlap

ChIP K562 ENCFF403WPG 344 bp overlap

CTCF 10 datasets

ChIP B cell ENCFF506FKC 158 bp overlap

ChIP B cell ENCFF506FKC 376 bp overlap

ChIP MM1-S GSE43743.CTCF.MM1-S 140 bp overlap

ChIP brain ENCFF685VRG 330 bp overlap

ChIP chondrocyte ENCFF134ORZ 74 bp overlap

ChIP chondrocyte ENCFF134ORZ 313 bp overlap

ChIP nephron ENCFF589HXU 131 bp overlap

ChIP nephron ENCFF589HXU 337 bp overlap

ChIP spleen ENCFF326DUY 153 bp overlap

ChIP spleen ENCFF326DUY 356 bp overlap

DPF2 2 datasets

ChIP GM12878 ENCFF681AJV 395 bp overlap

ChIP GM12878 ENCFF681AJV 349 bp overlap

ChIP K562 ENCFF622HMZ 425 bp overlap

ChIP GM12878 ENCFF813OXE 265 bp overlap

ChIP GM12878 ENCFF266FYW 336 bp overlap

ELF1 5 datasets

ChIP GM12878 ENCFF692SMY 321 bp overlap

ChIP GM12878 ENCSR000BMB.ELF1.GM12878 140 bp overlap

ChIP GM12878 ENCSR000BMB.ELF1.GM12878 199 bp overlap

ChIP K-562 ENCSR000BMD.ELF1.K-562 117 bp overlap

ChIP K562 ENCFF496AKI 221 bp overlap

ChIP AMLPZ12 GSE23730.ERG.AMLPZ12 203 bp overlap

ChIP ME-1 GSE46044.ERG.ME-1 247 bp overlap

ChIP SKNO-1 GSE23730.ERG.SKNO-1 363 bp overlap

FLI1 2 datasets

ChIP SKNO-1 GSE23730.FLI1.SKNO-1 453 bp overlap

ChIP UAE_ZINC GSE23730.FLI1.UAE_ZINC 224 bp overlap

GATA2 1 dataset

ChIP ME-1_CBFB-MYH11-KD GSE117138.GATA2.ME-1_CBFB-MYH11-KD 309 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 246 bp overlap

ChIP DE DE-GATA4-2 225 bp overlap

GATA6 6 datasets

ChIP DE DE-GATA6-1 246 bp overlap

ChIP DE DE-GATA6-2 164 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 251 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 157 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 299 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 162 bp overlap

GATAD2B 1 dataset

ChIP GM12878 ENCFF781IAU 338 bp overlap

GLIS3 1 dataset

ChIP H9_plus GSE109562.GLIS3.H9_plus 333 bp overlap

HDAC1 2 datasets

ChIP K562 ENCFF968WBH 373 bp overlap

ChIP K562 ENCFF968WBH 330 bp overlap

ChIP GM12878 ENCFF653WYI 343 bp overlap

IKZF1 7 datasets

ChIP GM12878 ENCFF753XDO 260 bp overlap

ChIP GM12878 ENCFF753XDO 270 bp overlap

ChIP GM12878 ENCFF824TGK 196 bp overlap

ChIP GM12878 ENCFF824TGK 286 bp overlap

ChIP K562 ENCFF348IBL 81 bp overlap

ChIP K562 ENCFF771OHZ 114 bp overlap

ChIP pre-B-cell GSE107886.IKZF1.pre-B-cell 133 bp overlap

IKZF2 1 dataset

ChIP GM12878 ENCFF918AID 296 bp overlap

ChIP K562 ENCFF277KTJ 456 bp overlap

ChIP T-cell GSE136853.IRF4.T-cell 163 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 308 bp overlap

KDM1A 2 datasets

ChIP K562 ENCFF128TYE 260 bp overlap

ChIP NB4_DMSO GSE128528.KDM1A.NB4_DMSO 230 bp overlap

KDM5B 1 dataset

ChIP K562 ENCFF049WWX 212 bp overlap

KMT2A 2 datasets

ChIP OCI-AML-3_VTP GSE129636.KMT2A.OCI-AML-3_VTP 230 bp overlap

ChIP RCH-ACV GSE83671.KMT2A.RCH-ACV 287 bp overlap

ChIP K-562 ENCSR000EFX.MAZ.K-562 101 bp overlap

ChIP K562 ENCFF333ZIV 280 bp overlap

ChIP K562 ENCFF809XHP 358 bp overlap

ChIP K562 ENCFF982GSZ 390 bp overlap

ChIP K562 ENCFF982GSZ 373 bp overlap

MED1 2 datasets

ChIP GM12878 GSE93080.MED1.GM12878 148 bp overlap

ChIP MM1-S_JQ1_500NM GSE42355.MED1.MM1-S_JQ1_500NM 271 bp overlap

ChIP Kelly GSE94782.MYCN.Kelly 111 bp overlap

NFXL1 3 datasets

ChIP GM12878 ENCSR746XEG.NFXL1.GM12878 160 bp overlap

ChIP K-562 ENCSR085DDI.NFXL1.K-562 175 bp overlap

ChIP K562 ENCFF619QDE 161 bp overlap

NIPBL 1 dataset

ChIP GM12878 GSE93080.NIPBL.GM12878 120 bp overlap

ChIP GM12878 ENCFF392NLB 210 bp overlap

NR2F1 1 dataset

ChIP GM12878 ENCFF273VKX 350 bp overlap

NRF1 3 datasets

ChIP K562 ENCFF130SGK 289 bp overlap

ChIP K562 ENCFF689EWI 268 bp overlap

ChIP K562 ENCFF791UHF 241 bp overlap

PHF8 3 datasets

ChIP HepG2 ENCFF065NWR 418 bp overlap

ChIP K-562 ENCSR000AQH.PHF8.K-562 362 bp overlap

ChIP K562 ENCFF217UCA 385 bp overlap

POLR2A 52 datasets

ChIP GM12878 ENCFF263VRI 397 bp overlap

ChIP GM12878 ENCFF521FXC 294 bp overlap

ChIP GM12892 ENCFF245LYF 476 bp overlap

ChIP GM12892 ENCFF506PGQ 391 bp overlap

ChIP GM15510 ENCFF880HVJ 436 bp overlap

ChIP GM18505 ENCFF311CYB 410 bp overlap

ChIP GM18526 ENCFF599EPS 107 bp overlap

ChIP GM18526 ENCFF599EPS 152 bp overlap

ChIP GM18951 ENCFF079KKO 251 bp overlap

ChIP GM19099 ENCFF726IBN 172 bp overlap

ChIP GM19193 ENCFF599VTO 84 bp overlap

ChIP GM19193 ENCFF599VTO 145 bp overlap

ChIP K562 ENCFF137JSF 405 bp overlap

ChIP K562 ENCFF215CWW 432 bp overlap

ChIP K562 ENCFF262YXJ 476 bp overlap

ChIP K562 ENCFF836GHX 234 bp overlap

ChIP K562 ENCFF836GHX 346 bp overlap

ChIP Peyer's patch ENCFF767HVN 320 bp overlap

ChIP Raji ENCFF613VGX 187 bp overlap

ChIP adrenal gland ENCFF843OBJ 445 bp overlap

ChIP adrenal gland ENCFF892SFM 341 bp overlap

ChIP body of pancreas ENCFF501FEC 389 bp overlap

ChIP body of pancreas ENCFF675RCN 410 bp overlap

ChIP body of pancreas ENCFF727UBE 376 bp overlap

ChIP erythroblast ENCFF498VMR 373 bp overlap

ChIP esophagus muscularis mucosa ENCFF759BBR 307 bp overlap

ChIP esophagus muscularis mucosa ENCFF791ZXN 422 bp overlap

ChIP esophagus squamous epithelium ENCFF297FPP 305 bp overlap

ChIP esophagus squamous epithelium ENCFF708IOX 394 bp overlap

ChIP gastroesophageal sphincter ENCFF238INU 410 bp overlap

ChIP gastroesophageal sphincter ENCFF461UHJ 385 bp overlap

ChIP heart left ventricle ENCFF591JWH 386 bp overlap

ChIP prostate gland ENCFF832RQK 281 bp overlap

ChIP sigmoid colon ENCFF725QFT 346 bp overlap

ChIP spleen ENCFF044PYR 233 bp overlap

ChIP spleen ENCFF446ZGT 427 bp overlap

ChIP spleen ENCFF706IUS 320 bp overlap

ChIP spleen ENCFF955VIQ 291 bp overlap

ChIP stomach ENCFF820WZN 274 bp overlap

ChIP suprapubic skin ENCFF832BBO 365 bp overlap

ChIP thyroid gland ENCFF979LRR 393 bp overlap

ChIP tibial nerve ENCFF162IDM 271 bp overlap

ChIP tibial nerve ENCFF983HAU 409 bp overlap

ChIP transverse colon ENCFF098HBD 397 bp overlap

ChIP transverse colon ENCFF098HBD 295 bp overlap

ChIP transverse colon ENCFF193UMS 476 bp overlap

ChIP transverse colon ENCFF964EQU 282 bp overlap

ChIP upper lobe of left lung ENCFF199JUI 358 bp overlap

ChIP upper lobe of left lung ENCFF504HCM 420 bp overlap

ChIP upper lobe of left lung ENCFF640VPA 343 bp overlap

ChIP vagina ENCFF216BYP 273 bp overlap

ChIP vagina ENCFF384GAB 416 bp overlap

POLR2G 2 datasets

ChIP K562 ENCFF047BLG 425 bp overlap

ChIP K562 ENCFF648YPL 335 bp overlap

POU5F1 1 dataset

ChIP DE_D1 DED1-OCT4_Batch_II 443 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 405 bp overlap

ChIP TSU-1621MT GSE60477.RARA.TSU-1621MT 223 bp overlap

RBFOX2 3 datasets

ChIP K-562 ENCSR822LBD.RBFOX2.K-562 356 bp overlap

ChIP K-562 GSE120104.RBFOX2.K-562 356 bp overlap

ChIP K562 ENCFF967GRF 417 bp overlap

ChIP aortic-endothelial-cell_IL1B_D9 GSE139377.RELA.aortic-endothelial-cell_IL1B_D9 185 bp overlap

REST 2 datasets

ChIP K-562 ENCSR000BMW.REST.K-562 50 bp overlap

ChIP K562 ENCFF430APM 88 bp overlap

ChIP K562 ENCFF653BQJ 391 bp overlap

RUNX1 1 dataset

ChIP SKNO-1 GSE23730.RUNX1.SKNO-1 255 bp overlap

SMAD2_3 4 datasets

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 475 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 344 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 265 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 476 bp overlap

ChIP monocyte_IFNg-LPS GSE120943.SMC1.monocyte_IFNg-LPS 204 bp overlap

SMC1A 1 dataset

ChIP monocyte_INFg GSE98367.SMC1A.monocyte_INFg 139 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 383 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 476 bp overlap

ChIP GM12878 ENCSR000BHK.SP1.GM12878 118 bp overlap

STAT1_pS727 1 dataset

ChIP SET-2 GSE100566.STAT1_pS727.SET-2 220 bp overlap

STAT3 1 dataset

ChIP monocyte_IFNg GSE120943.STAT3.monocyte_IFNg 131 bp overlap

SUPT5H 1 dataset

ChIP K562 ENCFF902PAW 157 bp overlap

ChIP HepG2 ENCFF946IUP 463 bp overlap

TARDBP 2 datasets

ChIP K-562 GSE120104.TARDBP.K-562 150 bp overlap

ChIP K-562 ENCSR429XTR.TARDBP.K-562 142 bp overlap

VEZF1 1 dataset

ChIP K562 ENCFF053XDV 440 bp overlap

ChIP GM12892 ENCFF802MHJ 106 bp overlap

ChIP HepG2 ENCFF956MUY 190 bp overlap

ChIP liver ENCFF400MBC 405 bp overlap

ChIP GM12878 ENCSR000BND.ZEB1.GM12878 125 bp overlap

ZFP91 1 dataset

ChIP K562 ENCFF501CDP 123 bp overlap

ChIP HepG2 ENCFF016NZF 464 bp overlap

ChIP K562 ENCFF169LZT 476 bp overlap

ChIP K562 ENCFF536AJO 476 bp overlap

ChIP K562 ENCFF536AJO 476 bp overlap

ZNF263 8 datasets

ChIP HEK293 ENCFF336CWQ 214 bp overlap

ChIP HEK293T GSE78099.ZNF263.HEK293T 88 bp overlap

ChIP Hep-G2 ENCSR313MMD.ZNF263.Hep-G2 189 bp overlap

ChIP HepG2 ENCFF626SSV 182 bp overlap

ChIP K-562 ENCSR000EWN.ZNF263.K-562 416 bp overlap

ChIP K562 ENCFF640RNA 227 bp overlap

ChIP K562 ENCFF650LPZ 181 bp overlap

ChIP WTC11 ENCFF893RTM 97 bp overlap

ZNF407 2 datasets

ChIP K562 ENCFF568QZW 162 bp overlap

ChIP K562 ENCFF893ASX 331 bp overlap

ZNF687 1 dataset

ChIP GM12878 ENCFF233SGE 327 bp overlap