chr16 : 89,958,035 – 89,958,351
316 bp 78 TFs 1 linked gene
This 316 bp open chromatin element is linked to DEF8 and is bound by 78 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
DEF8 9.2 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr16:89,953,035 – 89,963,351
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
78 transcription factors
Source
Cell type
AFF4 1 dataset
ChIP HeLa_EGF GSE40632.AFF4.HeLa_EGF 74 bp overlap
AHR 2 datasets
ChIP GM01310_DMSO GSE116632.AHR.GM01310_DMSO 139 bp overlap
ChIP MCF-7_DMSO_45min GSE90550.AHR.MCF-7_DMSO_45min 102 bp overlap
ARID2 2 datasets
ChIP NGP GSE134626.ARID2.NGP 164 bp overlap
ChIP NGP_ARID1A-mut2 GSE134626.ARID2.NGP_ARID1A-mut2 287 bp overlap
ASH1L 2 datasets
ChIP K-562 ENCSR115BBC.ASH1L.K-562 273 bp overlap
ChIP K562 ENCFF808EMX 117 bp overlap
ATF3 2 datasets
ChIP H1 ENCFF852GZY 241 bp overlap
ChIP WA01 ENCSR000BKC.ATF3.WA01 136 bp overlap
BCL11A 8 datasets
ChIP CD34_Day5_30min GSE104676.BCL11A.CD34_Day5_30min 132 bp overlap
ChIP CD34_Day7_60min GSE104676.BCL11A.CD34_Day7_60min 54 bp overlap
ChIP CD34_Day7_90min GSE104676.BCL11A.CD34_Day7_90min 67 bp overlap
ChIP CD34_Day9_30min GSE104676.BCL11A.CD34_Day9_30min 155 bp overlap
ChIP CD34_Day9_60min GSE104676.BCL11A.CD34_Day9_60min 114 bp overlap
ChIP CD34_Day9_90min GSE104676.BCL11A.CD34_Day9_90min 168 bp overlap
ChIP HUDEP-2_30min GSE104676.BCL11A.HUDEP-2_30min 253 bp overlap
ChIP HUDEP-2_90min GSE104676.BCL11A.HUDEP-2_90min 200 bp overlap
BCL6 1 dataset
ChIP OCI-Ly1 GSE29282.BCL6.OCI-Ly1 108 bp overlap
BHLHE40 1 dataset
ChIP Hep-G2 ENCSR000EDT.BHLHE40.Hep-G2 176 bp overlap
BRD2 2 datasets
ChIP THP-1_iBET-BD1 GSE138084.BRD2.THP-1_iBET-BD1 191 bp overlap
ChIP THP-1_iBET-BD2 GSE138084.BRD2.THP-1_iBET-BD2 115 bp overlap
BRD4 4 datasets
ChIP SK-N-BE2-C_Naive-veh GSE107706.BRD4.SK-N-BE2-C_Naive-veh 138 bp overlap
ChIP THP-1_DMSO GSE138084.BRD4.THP-1_DMSO 51 bp overlap
ChIP THP-1_iBET-BD2 GSE138084.BRD4.THP-1_iBET-BD2 58 bp overlap
ChIP hESC GSE33281.BRD4.hESC 53 bp overlap
CEBPZ 3 datasets
ChIP GM12878 ENCSR347NOB.CEBPZ.GM12878 136 bp overlap
ChIP K-562 ENCSR618GDK.CEBPZ.K-562 285 bp overlap
ChIP K562 ENCFF909BYC 316 bp overlap
CHD2 6 datasets
ChIP H1 ENCFF991MKH 311 bp overlap
ChIP K-562 ENCSR000EHD.CHD2.K-562 215 bp overlap
ChIP K562 ENCFF857WME 310 bp overlap
ChIP SK-N-SH ENCFF669KMB 310 bp overlap
ChIP SK-N-SH ENCSR274SLQ.CHD2.SK-N-SH 220 bp overlap
ChIP WA01 ENCSR000EBT.CHD2.WA01 225 bp overlap
CREB1 5 datasets
ChIP H1 ENCFF955PMP 294 bp overlap
ChIP MCF-7 ENCFF341ZEM 316 bp overlap
ChIP MCF-7 ENCFF867SAS 316 bp overlap
ChIP MCF-7 ENCSR620DUQ.CREB1.MCF-7 291 bp overlap
ChIP MCF-7 ENCSR897JAS.CREB1.MCF-7 280 bp overlap
CTCF 3 datasets
ChIP RH4 GSE83726.CTCF.RH4 218 bp overlap
ChIP neutrophil ENCFF770HHA 316 bp overlap
ChIP neutrophil ENCSR785YRL.CTCF.neutrophil 316 bp overlap
DDX20 4 datasets
ChIP K-562 ENCSR446LAV.DDX20.K-562 316 bp overlap
ChIP K562 ENCFF205RDN 314 bp overlap
ChIP MCF-7 ENCFF142TOQ 124 bp overlap
ChIP MCF-7 ENCSR330ADN.DDX20.MCF-7 239 bp overlap
DNMT3B 2 datasets
ChIP HUES-8 GSE99346.DNMT3B.HUES-8 154 bp overlap
ChIP HUES-8_TripleKO-TET1-2-3 GSE99346.DNMT3B.HUES-8_TripleKO-TET1-2-3 316 bp overlap
DPF1 2 datasets
ChIP K-562 GSE97661.DPF1.K-562 187 bp overlap
ChIP MCF-7 GSE97661.DPF1.MCF-7 265 bp overlap
E2F6 2 datasets
ChIP H1 ENCFF785DWK 242 bp overlap
ChIP WA01 ENCSR000BSI.E2F6.WA01 112 bp overlap
E4F1 1 dataset
ChIP K-562 ENCSR731LHZ.E4F1.K-562 279 bp overlap
ELL2 2 datasets
ChIP HeLa_DOX GSE40632.ELL2.HeLa_DOX 316 bp overlap
ChIP HeLa_EGF GSE40632.ELL2.HeLa_EGF 316 bp overlap
ESR1 10 datasets
ChIP MCF-7 GSE76893.ESR1.MCF-7 263 bp overlap
ChIP MCF-7_E2 GSE115607.ESR1.MCF-7_E2 249 bp overlap
ChIP MCF-7_H3B-6545 GSE115607.ESR1.MCF-7_H3B-6545 290 bp overlap
ChIP MCF-7_PaPE-1 GSE93510.ESR1.MCF-7_PaPE-1 240 bp overlap
ChIP MCF-7_PaPE-1_OA GSE93510.ESR1.MCF-7_PaPE-1_OA 316 bp overlap
ChIP MCF-7_Sat-H3B-6545 GSE115607.ESR1.MCF-7_Sat-H3B-6545 159 bp overlap
ChIP MCF-7_estradiol-DHT_45min GSE99626.ESR1.MCF-7_estradiol-DHT_45min 213 bp overlap
ChIP T-47D_Y537S GSE148277.ESR1.T-47D_Y537S 56 bp overlap
ChIP T-47D_Y537S GSE148277.ESR1.T-47D_Y537S 172 bp overlap
ChIP T-47D_Y537S_E2 GSE148277.ESR1.T-47D_Y537S_E2 198 bp overlap
ETS1 1 dataset
ChIP cardiomyocyte_D9 GSE129986.ETS1.cardiomyocyte_D9 238 bp overlap
EZH2 1 dataset
ChIP RH30_DMSO GSE85169.EZH2.RH30_DMSO 316 bp overlap
FOS 4 datasets
ChIP HCT-116_A7A GSE152144.FOS.HCT-116_A7A 316 bp overlap
ChIP Hep-G2 ENCSR177HDZ.FOS.Hep-G2 216 bp overlap
ChIP K-562 ENCSR000FAI.FOS.K-562 241 bp overlap
ChIP K562 ENCFF951GBI 265 bp overlap
GATA1 1 dataset
ChIP CD34_Day9_30min GSE104676.GATA1.CD34_Day9_30min 98 bp overlap
HDGF 1 dataset
ChIP K-562 ENCSR197ALX.HDGF.K-562 218 bp overlap
HIVEP1 1 dataset
ChIP Hep-G2 ENCSR697WMX.HIVEP1.Hep-G2 316 bp overlap
HNF1B 1 dataset
ChIP PANC-1_HNF1B-OE GSE119930.HNF1B.PANC-1_HNF1B-OE 316 bp overlap
INTS13 1 dataset
ChIP monocyte GSE106359.INTS13.monocyte 316 bp overlap
IRF3 2 datasets
ChIP SK-N-SH ENCFF921DIM 245 bp overlap
ChIP SK-N-SH ENCSR422ZAO.IRF3.SK-N-SH 192 bp overlap
KMT2A 2 datasets
ChIP Hep-G2 ENCSR692GFR.KMT2A.Hep-G2 62 bp overlap
ChIP MOLM-13_VTP-d3-180110 GSE127507.KMT2A.MOLM-13_VTP-d3-180110 283 bp overlap
KMT2B 1 dataset
ChIP AML_OG86 GSE112074.KMT2B.AML_OG86 287 bp overlap
KMT2B-D 1 dataset
ChIP SW480 GSE115985.KMT2B-D.SW480 313 bp overlap
MAX 8 datasets
ChIP A-549 ENCSR000DYG.MAX.A-549 138 bp overlap
ChIP A549 ENCFF985GDG 314 bp overlap
ChIP H1 ENCFF914VQY 193 bp overlap
ChIP Hep-G2 ENCSR000EDS.MAX.Hep-G2 252 bp overlap
ChIP Hep-G2 ENCSR168DYA.MAX.Hep-G2 118 bp overlap
ChIP NB4 ENCFF966MWB 155 bp overlap
ChIP NB4 ENCSR000EHS.MAX.NB4 278 bp overlap
ChIP WTC11 ENCFF223QFY 315 bp overlap
MBD2 1 dataset
ChIP K562 ENCFF217VLV 301 bp overlap
MXI1 2 datasets
ChIP SK-N-SH ENCFF746HVJ 305 bp overlap
ChIP SK-N-SH ENCSR000EIA.MXI1.SK-N-SH 142 bp overlap
MYC 6 datasets
ChIP MCF-7 ENCFF394LGD 204 bp overlap
ChIP MCF-7 ENCFF542NWJ 197 bp overlap
ChIP MCF-7 ENCFF767RTQ 138 bp overlap
ChIP MCF-7 ENCSR000DMQ.MYC.MCF-7 132 bp overlap
ChIP NB4 ENCFF142PRP 183 bp overlap
ChIP NB69 GSE138295.MYC.NB69 218 bp overlap
MYCN 6 datasets
ChIP BE2C GSE80151.MYCN.BE2C 164 bp overlap
ChIP CHP-134 GSE129588.MYCN.CHP-134 316 bp overlap
ChIP COG-N-415 GSE138295.MYCN.COG-N-415 316 bp overlap
ChIP Kelly GSE94822.MYCN.Kelly 102 bp overlap
ChIP LA-N-5 GSE138295.MYCN.LA-N-5 277 bp overlap
ChIP SK-N-BE2-C GSE80151.MYCN.SK-N-BE2-C 164 bp overlap
MYOD1 3 datasets
ChIP IMR-90_GM GSE128527.MYOD1.IMR-90_GM 269 bp overlap
ChIP RH4 GSE83726.MYOD1.RH4 183 bp overlap
ChIP myoblast GSE50413.MYOD1.myoblast 156 bp overlap
MYOG 1 dataset
ChIP RH30_DMSO GSE85169.MYOG.RH30_DMSO 147 bp overlap
NEUROD1 2 datasets
ChIP K-562 ENCSR986CDX.NEUROD1.K-562 235 bp overlap
ChIP K562 ENCFF718PFO 316 bp overlap
NFAT5 1 dataset
ChIP Hep-G2 ENCSR565BVI.NFAT5.Hep-G2 167 bp overlap
NFE2 1 dataset
ChIP ProEs GSE59087.NFE2.ProEs 96 bp overlap
NFYA 8 datasets
ChIP HeLa-S3 ENCFF016YWF 316 bp overlap
ChIP HeLa-S3 ENCSR000DNS.NFYA.HeLa-S3 316 bp overlap
ChIP Hep-G2 ENCSR124APT.NFYA.Hep-G2 316 bp overlap
ChIP HepG2 ENCFF883OMO 237 bp overlap
ChIP K-562 ENCSR000EGR.NFYA.K-562 316 bp overlap
ChIP K-562 GSE26439.NFYA.K-562 316 bp overlap
ChIP K562 ENCFF666BET 314 bp overlap
ChIP K562 ENCFF732HOX 316 bp overlap
NFYB 6 datasets
ChIP HeLa-S3 ENCSR000DNR.NFYB.HeLa-S3 316 bp overlap
ChIP Hep-G2 ENCSR935GZV.NFYB.Hep-G2 316 bp overlap
ChIP HepG2 ENCFF174VYX 316 bp overlap
ChIP K-562 ENCSR000EGQ.NFYB.K-562 297 bp overlap
ChIP K-562 GSE26439.NFYB.K-562 316 bp overlap
ChIP WTC11 ENCFF751ZTQ 316 bp overlap
NFYC 2 datasets
ChIP Hep-G2 ENCSR569ARC.NFYC.Hep-G2 316 bp overlap
ChIP HepG2 ENCFF836FYP 316 bp overlap
NIPBL 5 datasets
ChIP HCT-116_RAD21-mAC GSE104888.NIPBL.HCT-116_RAD21-mAC 308 bp overlap
ChIP HCT-116_RAD21-mAC_500uM_auxin GSE104888.NIPBL.HCT-116_RAD21-mAC_500uM_auxin 296 bp overlap
ChIP HEK293T_CRISPR GSE122299.NIPBL.HEK293T_CRISPR 303 bp overlap
ChIP HEK293T_CRISPR-2 GSE122299.NIPBL.HEK293T_CRISPR-2 316 bp overlap
ChIP HEK293T_WT GSE122299.NIPBL.HEK293T_WT 298 bp overlap
NOTCH1 1 dataset
ChIP HPBALL GSE39263.NOTCH1.HPBALL 226 bp overlap
NR2C2 1 dataset
ChIP HepG2 ENCFF944PRH 316 bp overlap
NR3C1 1 dataset
ChIP BEAS-2B_TNF_IA1 GSE125623.NR3C1.BEAS-2B_TNF_IA1 199 bp overlap
PBX1-2-3 1 dataset
ChIP 697 GSE138031.PBX1-2-3.697 174 bp overlap
PBX3 1 dataset
ChIP SK-N-SH ENCFF876BMC 250 bp overlap
PKNOX1 6 datasets
ChIP HEK293T ENCFF174WDB 316 bp overlap
ChIP HEK293T ENCSR233FAG.PKNOX1.HEK293T 283 bp overlap
ChIP K-562 ENCSR115SMW.PKNOX1.K-562 316 bp overlap
ChIP K562 ENCFF236IUS 316 bp overlap
ChIP MCF-7 ENCFF116OCS 314 bp overlap
ChIP MCF-7 ENCSR986XYK.PKNOX1.MCF-7 316 bp overlap
PLAG1 1 dataset
ChIP K-562 GSE111469.PLAG1.K-562 310 bp overlap
POLR2A 1 dataset
ChIP NB4 ENCFF780KAX 220 bp overlap
POU2F1 1 dataset
ChIP 22Rv1_Veh GSE123565.POU2F1.22Rv1_Veh 247 bp overlap
RAD21 1 dataset
ChIP THP-1_eGFP-IFNb GSE103477.RAD21.THP-1_eGFP-IFNb 259 bp overlap
RAD51 4 datasets
ChIP K-562 ENCSR524BUE.RAD51.K-562 311 bp overlap
ChIP K562 ENCFF133ELP 206 bp overlap
ChIP MCF-7 ENCFF128SEB 316 bp overlap
ChIP MCF-7 ENCSR442VBJ.RAD51.MCF-7 299 bp overlap
RBFOX2 2 datasets
ChIP K-562 GSE120104.RBFOX2.K-562 193 bp overlap
ChIP K-562 ENCSR822LBD.RBFOX2.K-562 181 bp overlap
RBM39 2 datasets
ChIP Hep-G2 GSE120104.RBM39.Hep-G2 186 bp overlap
ChIP HepG2 ENCFF084YZE 316 bp overlap
REST 1 dataset
ChIP K-562 ENCSR137ZMQ.REST.K-562 229 bp overlap
RUNX1_mut 1 dataset
ChIP CD34 GSE111917.RUNX1_mut.CD34 164 bp overlap
SMARCA4 5 datasets
ChIP A-549_AG15721 GSE132290.SMARCA4.A-549_AG15721 63 bp overlap
ChIP NGP GSE134626.SMARCA4.NGP 176 bp overlap
ChIP NGP_ARID1A-het GSE134626.SMARCA4.NGP_ARID1A-het 230 bp overlap
ChIP NGP_ARID1A-mut1 GSE134626.SMARCA4.NGP_ARID1A-mut1 205 bp overlap
ChIP NGP_ARID1A-mut2 GSE134626.SMARCA4.NGP_ARID1A-mut2 316 bp overlap
SMC1A 1 dataset
ChIP HCT-116 GSE112000.SMC1A.HCT-116 188 bp overlap
SP1 13 datasets
ChIP A-549 ENCSR000BPE.SP1.A-549 306 bp overlap
ChIP GM12878 ENCFF620LDJ 315 bp overlap
ChIP GM12878 ENCSR000BHK.SP1.GM12878 231 bp overlap
ChIP H1 ENCFF263FUH 181 bp overlap
ChIP HCT-116 ENCSR000BSF.SP1.HCT-116 212 bp overlap
ChIP HCT116 ENCFF800LBN 316 bp overlap
ChIP HEK293T ERP007114.SP1.HEK293T 278 bp overlap
ChIP Hep-G2 ENCSR000BJX.SP1.Hep-G2 212 bp overlap
ChIP Hep-G2 ENCSR460YAM.SP1.Hep-G2 208 bp overlap
ChIP HepG2 ENCFF123KAM 299 bp overlap
ChIP K562 ENCFF907BMO 316 bp overlap
ChIP WA01 ENCSR000BIR.SP1.WA01 314 bp overlap
ChIP WTC11 ENCFF688PEU 316 bp overlap
SP2 10 datasets
ChIP H1 ENCFF903ACN 316 bp overlap
ChIP HEK293 ENCFF181QXT 316 bp overlap
ChIP HEK293 ENCSR807LQP.SP2.HEK293 316 bp overlap
ChIP HEK293 GSE76494.SP2.HEK293 316 bp overlap
ChIP HEK293T ERP007114.SP2.HEK293T 316 bp overlap
ChIP Hep-G2 ENCSR000BOU.SP2.Hep-G2 229 bp overlap
ChIP HepG2 ENCFF667RFH 255 bp overlap
ChIP K-562 ENCSR000BNL.SP2.K-562 261 bp overlap
ChIP K562 ENCFF891GNQ 237 bp overlap
ChIP WA01 ENCSR000BQG.SP2.WA01 314 bp overlap
SP4 2 datasets
ChIP HEK293 GSE76494.SP4.HEK293 165 bp overlap
ChIP HepG2 ENCFF865DSQ 316 bp overlap
SPI1 3 datasets
ChIP THP-1 GSE128834.SPI1.THP-1 72 bp overlap
ChIP macrophage_D7_donorP GSE128834.SPI1.macrophage_D7_donorP 151 bp overlap
ChIP primary-monocyte_18h_donorO GSE128834.SPI1.primary-monocyte_18h_donorO 145 bp overlap
SREBP2 2 datasets
ChIP monocyte GSE129202.SREBP2.monocyte 316 bp overlap
ChIP monocyte_TNF GSE129202.SREBP2.monocyte_TNF 316 bp overlap
TCF3 1 dataset
ChIP Kasumi-1 GSE43834.TCF3.Kasumi-1 69 bp overlap
TCF4 1 dataset
ChIP GEN2-2 GSE76147.TCF4.GEN2-2 148 bp overlap
TWIST1 2 datasets
ChIP BE2C GSE80151.TWIST1.BE2C 167 bp overlap
ChIP SK-N-BE2-C GSE80151.TWIST1.SK-N-BE2-C 167 bp overlap
USF1 21 datasets
ChIP A-549 ENCSR000BPV.USF1.A-549 316 bp overlap
ChIP A-549 ENCSR000BJB.USF1.A-549 251 bp overlap
ChIP A-549 ENCSR000BHX.USF1.A-549 235 bp overlap
ChIP GM12878 ENCFF880HJL 257 bp overlap
ChIP GM12878 ENCSR000BGI.USF1.GM12878 156 bp overlap
ChIP H1 ENCFF090WVU 221 bp overlap
ChIP HCT-116 ENCSR000BVK.USF1.HCT-116 287 bp overlap
ChIP HCT116 ENCFF330PYP 235 bp overlap
ChIP Hep-G2 ENCSR000BGM.USF1.Hep-G2 228 bp overlap
ChIP HepG2 ENCFF201JKA 307 bp overlap
ChIP HepG2 ENCFF807KYJ 187 bp overlap
ChIP Ishikawa ENCFF728IEG 217 bp overlap
ChIP Ishikawa ENCSR000BSX.USF1.Ishikawa 297 bp overlap
ChIP K-562 ENCSR000BKT.USF1.K-562 302 bp overlap
ChIP K562 ENCFF202SFC 144 bp overlap
ChIP K562 ENCFF633EZB 168 bp overlap
ChIP SK-N-SH ENCFF967PDP 237 bp overlap
ChIP SK-N-SH ENCSR000BTZ.USF1.SK-N-SH 293 bp overlap
ChIP SK-N-SH ENCSR000BMF.USF1.SK-N-SH 302 bp overlap
ChIP WA01 ENCSR000BIU.USF1.WA01 303 bp overlap
ChIP WTC11 ENCFF699QGS 224 bp overlap
USF2 20 datasets
ChIP A-549 ENCSR563FBT.USF2.A-549 316 bp overlap
ChIP A549 ENCFF343KII 296 bp overlap
ChIP GM12878 GSE97661.USF2.GM12878 316 bp overlap
ChIP H1 ENCFF434EDF 147 bp overlap
ChIP HeLa-S3 ENCFF765YUZ 285 bp overlap
ChIP HeLa-S3 ENCSR000ECW.USF2.HeLa-S3 125 bp overlap
ChIP Hep-G2 ENCSR145QNL.USF2.Hep-G2 316 bp overlap
ChIP Hep-G2 GSE97661.USF2.Hep-G2 316 bp overlap
ChIP Hep-G2 ENCSR000EEF.USF2.Hep-G2 253 bp overlap
ChIP HepG2 ENCFF433IUE 288 bp overlap
ChIP HepG2 ENCFF433IUE 258 bp overlap
ChIP HepG2 ENCFF671JRC 85 bp overlap
ChIP IMR-90 ENCFF438KUN 183 bp overlap
ChIP IMR-90 ENCSR513UQG.USF2.IMR-90 253 bp overlap
ChIP K-562 ENCSR578KEN.USF2.K-562 201 bp overlap
ChIP K562 ENCFF397QGU 265 bp overlap
ChIP SK-N-SH ENCFF736ZYW 257 bp overlap
ChIP SK-N-SH ENCSR945NFL.USF2.SK-N-SH 164 bp overlap
ChIP WA01 ENCSR000ECD.USF2.WA01 306 bp overlap
ChIP WTC11 ENCFF139JAW 316 bp overlap
ZBTB48 1 dataset
ChIP U2OS_ZBTB48-KO GSE96776.ZBTB48.U2OS_ZBTB48-KO 316 bp overlap
ZFX 1 dataset
ChIP HEK293T_FLAG GSE145160.ZFX.HEK293T_FLAG 60 bp overlap
ZNF687 1 dataset
ChIP HepG2 ENCFF653WIX 316 bp overlap
ZNF891 1 dataset
ChIP Hep-G2 ENCSR020CLV.ZNF891.Hep-G2 167 bp overlap
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