chr1:224,639,152–224,640,098

chr1 : 224,639,152 – 224,640,098

946 bp 68 TFs 5 linked genes

This 946 bp open chromatin element is linked to 5 target genes and is bound by 68 transcription factors.

Linked Genes

5 genes

Gene	Expression	Dist. to TSS	Distance	Link type
CNIH3		204.7 kb	Distal	Multiome
WDR26		204.8 kb	Distal	Multiome
ENSG00000286719		241.8 kb	Distal	Multiome
CNIH4		282.7 kb	Distal	Multiome
DNAH14		290.1 kb	Distal	Multiome+HiCAR

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

68 transcription factors

ChIP LNCaP GSE64656.AR.LNCaP 121 bp overlap

ChIP LNCaP ERP003503.AR.LNCaP 96 bp overlap

ChIP LNCaP GSE110655.AR.LNCaP 78 bp overlap

ChIP LNCaP ERP001226.AR.LNCaP 75 bp overlap

ChIP LNCaP-C4-2B_DHT GSE40050.AR.LNCaP-C4-2B_DHT 90 bp overlap

ChIP LNCaP-clone-FGC_DHT-ABBV-075 GSE118247.AR.LNCaP-clone-FGC_DHT-ABBV-075 63 bp overlap

ChIP LNCaP-clone-FGC_DHT-ABBV-744 GSE118247.AR.LNCaP-clone-FGC_DHT-ABBV-744 67 bp overlap

ChIP LNCaP-clone-FGC_DHT-DMSO GSE118247.AR.LNCaP-clone-FGC_DHT-DMSO 60 bp overlap

ChIP LNCaP_DHT24H GSE58428.AR.LNCaP_DHT24H 115 bp overlap

ChIP LNCaP_DHTTHZ1 GSE125245.AR.LNCaP_DHTTHZ1 85 bp overlap

ChIP LNCaP_DSG GSE114737.AR.LNCaP_DSG 92 bp overlap

ChIP LNCaP_FOXA1 ERP003503.AR.LNCaP_FOXA1 91 bp overlap

ChIP LNCaP_R1881 GSE62492.AR.LNCaP_R1881 65 bp overlap

ChIP LNCaP_SHCTR_DHT GSE62492.AR.LNCaP_SHCTR_DHT 174 bp overlap

ChIP LNCaP_SHFOXP1_DHT GSE62492.AR.LNCaP_SHFOXP1_DHT 76 bp overlap

ChIP LNCaP_r1881 GSE94682.AR.LNCaP_r1881 87 bp overlap

ChIP LNCaP_sgCHD1 GSE117430.AR.LNCaP_sgCHD1 87 bp overlap

ChIP LNCaP_sgCtrl GSE117430.AR.LNCaP_sgCtrl 260 bp overlap

ChIP LTAD_siControl GSE94577.AR.LTAD_siControl 52 bp overlap

ChIP VCaP GSE83650.AR.VCaP 54 bp overlap

ChIP VCaP GSE98809.AR.VCaP 54 bp overlap

ChIP VCaP-LTAD_DHT_10nM GSE94577.AR.VCaP-LTAD_DHT_10nM 181 bp overlap

ChIP VCaP-LTAD_DHT_1nM GSE94577.AR.VCaP-LTAD_DHT_1nM 107 bp overlap

ChIP VCaP_DHAT_18H GSE28950.AR.VCaP_DHAT_18H 73 bp overlap

ChIP VCaP_DHAT_2H GSE28950.AR.VCaP_DHAT_2H 229 bp overlap

ChIP VCaP_DHAT_2H GSE28950.AR.VCaP_DHAT_2H 142 bp overlap

ChIP VCaP_DHT GSE79128.AR.VCaP_DHT 102 bp overlap

ChIP VCaP_DHT24H GSE58428.AR.VCaP_DHT24H 357 bp overlap

ChIP VCaP_DHT24H_SHFOXA1 GSE58428.AR.VCaP_DHT24H_SHFOXA1 185 bp overlap

ChIP VCaP_DHT24H_SHRUNX1 GSE58428.AR.VCaP_DHT24H_SHRUNX1 269 bp overlap

ChIP VCaP_DHT24H_SHRUNX1 GSE58428.AR.VCaP_DHT24H_SHRUNX1 316 bp overlap

ChIP VCaP_Darolutamide GSE148358.AR.VCaP_Darolutamide 71 bp overlap

ChIP VCaP_R1881 GSE32892.AR.VCaP_R1881 205 bp overlap

ChIP VCaP_R1881 GSE32892.AR.VCaP_R1881 62 bp overlap

ChIP VCaP_R1881_10C26 GSE32892.AR.VCaP_R1881_10C26 69 bp overlap

ChIP VCaP_R1881_10C30 GSE32892.AR.VCaP_R1881_10C30 72 bp overlap

ChIP VCaP_R1881_1C26 GSE32892.AR.VCaP_R1881_1C26 55 bp overlap

ChIP VCaP_R1881_1C30 GSE32892.AR.VCaP_R1881_1C30 127 bp overlap

ChIP VCaP_SH1_DHT GSE79128.AR.VCaP_SH1_DHT 112 bp overlap

ChIP VCaP_SH2_DHT GSE79128.AR.VCaP_SH2_DHT 81 bp overlap

ChIP VCaP_SH2_R1881 GSE79128.AR.VCaP_SH2_R1881 75 bp overlap

ChIP VCaP_SH3_DHT GSE79128.AR.VCaP_SH3_DHT 93 bp overlap

ChIP VCaP_shCt GSE110655.AR.VCaP_shCt 65 bp overlap

ChIP VCaP_shERG GSE110655.AR.VCaP_shERG 82 bp overlap

ChIP prostate GSE65478.AR.prostate 58 bp overlap

ChIP prostate-cancer_PDX_92 GSE130408.AR.prostate-cancer_PDX_92 64 bp overlap

ChIP prostate-cancer_PDX_92 GSE130408.AR.prostate-cancer_PDX_92 110 bp overlap

ChIP prostate-cancer_shGREB1 GSE120680.AR.prostate-cancer_shGREB1 94 bp overlap

ChIP prostate-cancer_shRenilla GSE120680.AR.prostate-cancer_shRenilla 57 bp overlap

ChIP prostate_1798_T GSE130408.AR.prostate_1798_T 327 bp overlap

ARID1A 1 dataset

ChIP 12Z GSE129781.ARID1A.12Z 499 bp overlap

Ahr::Arnt 1 dataset

Motif DE_48h DE_48h-AhrArnt_MA0006.2 5 bp overlap

BAF155 1 dataset

ChIP VCaP_shARID1A GSE110655.BAF155.VCaP_shARID1A 54 bp overlap

BRD4 2 datasets

ChIP MDA-MB-231_JQ1-neg_L GSE136151.BRD4.MDA-MB-231_JQ1-neg_L 179 bp overlap

ChIP MDA-MB-231_JQ1-neg_S_3f GSE136151.BRD4.MDA-MB-231_JQ1-neg_S_3f 811 bp overlap

ChIP KB_IL GSE52469.CDK6.KB_IL 161 bp overlap

ChIP retina_Hu20 GSE137311.CRX.retina_Hu20 219 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 217 bp overlap

EP300 1 dataset

ChIP neural cell ENCFF442QNK 158 bp overlap

ERG 10 datasets

ChIP VCaP GSE28950.ERG.VCaP 79 bp overlap

ChIP VCaP_DHAT_18H GSE28950.ERG.VCaP_DHAT_18H 85 bp overlap

ChIP VCaP_DHAT_2H GSE28950.ERG.VCaP_DHAT_2H 85 bp overlap

ChIP VCaP_DHT GSE79128.ERG.VCaP_DHT 126 bp overlap

ChIP VCaP_ETOH GSE49091.ERG.VCaP_ETOH 63 bp overlap

ChIP VCaP_R1881 GSE49091.ERG.VCaP_R1881 71 bp overlap

ChIP VCaP_SH1_DHT GSE79128.ERG.VCaP_SH1_DHT 119 bp overlap

ChIP VCaP_SH2_DHT GSE79128.ERG.VCaP_SH2_DHT 50 bp overlap

ChIP VCaP_SH3_DHT GSE79128.ERG.VCaP_SH3_DHT 121 bp overlap

ChIP VCaP_shARID1A GSE110655.ERG.VCaP_shARID1A 52 bp overlap

ETV5::FOXI1 1 dataset

Motif DE_48h DE_48h-ETV5FOXI1_MA1946.2 12 bp overlap

EZH2 2 datasets

ChIP SF8628 GSE94834.EZH2.SF8628 249 bp overlap

ChIP SF8628 GSE94834.EZH2.SF8628 92 bp overlap

FOXA1 5 datasets

ChIP LNCaP_VEH GSE114266.FOXA1.LNCaP_VEH 52 bp overlap

ChIP prostate-cancer_PDX_189-3 GSE130408.FOXA1.prostate-cancer_PDX_189-3 78 bp overlap

ChIP prostate_2030_T GSE130408.FOXA1.prostate_2030_T 53 bp overlap

ChIP prostate_P5_T GSE130408.FOXA1.prostate_P5_T 65 bp overlap

ChIP prostate_P7_T GSE130408.FOXA1.prostate_P7_T 118 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 706 bp overlap

ChIP DE DE-FOXA2-2 763 bp overlap

FOXL2 2 datasets

ChIP HGrC1_C134W-TGF GSE138496.FOXL2.HGrC1_C134W-TGF 182 bp overlap

ChIP HGrC1_C134W-TGF_parental GSE138496.FOXL2.HGrC1_C134W-TGF_parental 284 bp overlap

GATA2 3 datasets

Motif DE_60h DE_60h-GATA2_MA0036.4 7 bp overlap

ChIP endothelial cell of umbilical vein ENCFF148NLK 441 bp overlap

ChIP endothelial_umbilical-vein ENCSR000EVW.GATA2.endothelial_umbilical-vein 250 bp overlap

GATA3 1 dataset

ChIP T47D-A1-2_EtOH GSE112491.GATA3.T47D-A1-2_EtOH 152 bp overlap

GATA4 6 datasets

ChIP DE DE-GATA4-1 841 bp overlap

ChIP DE DE-GATA4-2 849 bp overlap

Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap

ChIP foregut GSE117136.GATA4.foregut 666 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 378 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 605 bp overlap

GATA5 1 dataset

Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap

GATA6 12 datasets

ChIP DE DE-GATA6-1 814 bp overlap

ChIP DE DE-GATA6-2 832 bp overlap

Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 388 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 413 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 867 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 322 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 348 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 884 bp overlap

ChIP foregut GSE117136.GATA6.foregut 705 bp overlap

ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 473 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 448 bp overlap

Gata3 1 dataset

Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap

HNF4A 1 dataset

ChIP Caco-2_DIFF GSE23436.HNF4A.Caco-2_DIFF 241 bp overlap

HOXB13 9 datasets

ChIP prostate-cancer_PDX_170-2 GSE130408.HOXB13.prostate-cancer_PDX_170-2 56 bp overlap

ChIP prostate-cancer_PDX_92 GSE130408.HOXB13.prostate-cancer_PDX_92 100 bp overlap

ChIP prostate_2030_T GSE130408.HOXB13.prostate_2030_T 79 bp overlap

ChIP prostate_2078 GSE130408.HOXB13.prostate_2078 106 bp overlap

ChIP prostate_P19 GSE130408.HOXB13.prostate_P19 103 bp overlap

ChIP prostate_P19_T GSE130408.HOXB13.prostate_P19_T 58 bp overlap

ChIP prostate_P25 GSE130408.HOXB13.prostate_P25 84 bp overlap

ChIP prostate_P27 GSE130408.HOXB13.prostate_P27 102 bp overlap

ChIP prostate_P29_T GSE130408.HOXB13.prostate_P29_T 74 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 708 bp overlap

ChIP DE_D2 S54-DE-d2-JUN-exp2 376 bp overlap

MGA::EVX1 1 dataset

Motif DE_48h DE_48h-MGAEVX1_MA1960.2 11 bp overlap

Nfat5 1 dataset

Motif DE_48h DE_48h-Nfat5_MA0606.3 8 bp overlap

Nr5A2 1 dataset

Motif DE_48h DE_48h-Nr5A2_MA0505.3 9 bp overlap

ONECUT1 1 dataset

Motif DE_48h DE_48h-ONECUT1_MA0679.3 9 bp overlap

OTX2 2 datasets

ChIP retina_Hu7 GSE137311.OTX2.retina_Hu7 291 bp overlap

ChIP retina_pigment GSE60024.OTX2.retina_pigment 272 bp overlap

POLR2A 1 dataset

ChIP prostate gland ENCFF881OMH 128 bp overlap

PRDM1 1 dataset

ChIP HEK293 ENCFF302TBP 151 bp overlap

PRDM10 1 dataset

ChIP HEK293 ENCFF145WQQ 525 bp overlap

ChIP aortic-endothelial-cell_IL1B_D14 GSE139377.RELA.aortic-endothelial-cell_IL1B_D14 178 bp overlap

ChIP retina_Hu22 GSE137311.RORB.retina_Hu22 265 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 742 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 782 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 719 bp overlap

SMARCA4 1 dataset

ChIP endometrial-epithelial-cells_KO GSE106660.SMARCA4.endometrial-epithelial-cells_KO 505 bp overlap

SMC1 2 datasets

ChIP HCAEC GSE101921.SMC1.HCAEC 262 bp overlap

ChIP HCAEC GSE101921.SMC1.HCAEC 106 bp overlap

SOX15 1 dataset

Motif DE_48h DE_48h-SOX15_MA1152.2 7 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 424 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 686 bp overlap

SOX18 1 dataset

Motif DE_48h DE_48h-SOX18_MA1563.2 8 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 68 bp overlap

Motif DE_48h DE_48h-SOX8_MA0868.3 7 bp overlap

Motif DE_48h DE_48h-SOX9_MA0077.2 8 bp overlap

Motif DE_48h DE_48h-SRY_MA0084.2 7 bp overlap

STAT1 1 dataset

Motif DE_48h DE_48h-STAT1_MA0137.4 9 bp overlap

STAT3 1 dataset

ChIP MDA-MB-231_EtOH GSE85579.STAT3.MDA-MB-231_EtOH 172 bp overlap

Sox17 1 dataset

Motif DE_48h DE_48h-Sox17_MA0078.3 10 bp overlap

Motif DE_48h DE_48h-Sox5_MA0087.3 8 bp overlap

Motif DE_48h DE_48h-Sox6_MA0515.1 10 bp overlap

Motif DE_48h DE_48h-Sox7_MA2095.1 10 bp overlap

Stat4 1 dataset

Motif DE_48h DE_48h-Stat4_MA0518.2 10 bp overlap

Stat5a 1 dataset

Motif DE_48h DE_48h-Stat5a_MA1624.2 9 bp overlap

Stat5a::Stat5b 2 datasets

Motif DE_48h DE_48h-Stat5aStat5b_MA0519.2 9 bp overlap

Motif DE_48h DE_48h-Stat5aStat5b_MA0519.2 9 bp overlap

ChIP PRIMA5 GSE33850.TAL1.PRIMA5 177 bp overlap

TBX21 1 dataset

Motif DE_48h DE_48h-TBX21_MA0690.3 10 bp overlap

TEAD1 1 dataset

Motif DE_48h DE_48h-TEAD1_MA0090.4 9 bp overlap

TEAD4 1 dataset

Motif DE_48h DE_48h-TEAD4_MA0809.3 8 bp overlap

TRPS1 1 dataset

Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap

ZMYND8 1 dataset

ChIP MDA-MB-231 GSE108833.ZMYND8.MDA-MB-231 175 bp overlap

ZNF189 1 dataset

Motif DE_48h DE_48h-ZNF189_MA1725.2 9 bp overlap

ZNF341 2 datasets

Motif DE_48h DE_48h-ZNF341_MA1655.2 8 bp overlap

ChIP HEK293 ENCFF944VMC 121 bp overlap

ZNF418 1 dataset

Motif DE_48h DE_48h-ZNF418_MA1980.1 15 bp overlap

ZNF677 1 dataset

Motif DE_48h DE_48h-ZNF677_MA2101.1 12 bp overlap

ZNF680 1 dataset

Motif DE_48h DE_48h-ZNF680_MA1729.2 11 bp overlap

ZNF692 2 datasets

ChIP HEK293 ENCFF040AZE 466 bp overlap

ChIP HEK293 ENCSR418MKG.ZNF692.HEK293 325 bp overlap

ZNF708 1 dataset

Motif DE_48h DE_48h-ZNF708_MA1730.2 9 bp overlap