chr13:49,635,533–49,636,248

chr13 : 49,635,533 – 49,636,248

715 bp 74 TFs 7 linked genes

This 715 bp open chromatin element is linked to 7 target genes and is bound by 74 transcription factors.

Linked Genes

7 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ARL11		7.0 kb	Proximal	Proximity
RCBTB1		50.2 kb	Distal	Multiome
EBPL		55.7 kb	Distal	Multiome
PHF11		139.6 kb	Distal	Multiome
KPNA3		156.9 kb	Distal	Multiome
SETDB2		191.5 kb	Distal	Multiome
CAB39L		191.7 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

74 transcription factors

ARNTL 1 dataset

ChIP U2OS GSE44236.ARNTL.U2OS 50 bp overlap

ASH2L 2 datasets

ChIP GM12878 ENCSR849WCQ.ASH2L.GM12878 272 bp overlap

ChIP WA01 ENCSR850KIP.ASH2L.WA01 316 bp overlap

BRD4 4 datasets

ChIP CLL_patient1 GSE109411.BRD4.CLL_patient1 409 bp overlap

ChIP CLL_patient1_4h_CpG GSE109411.BRD4.CLL_patient1_4h_CpG 324 bp overlap

ChIP MV4-11_DMSO GSE71776.BRD4.MV4-11_DMSO 63 bp overlap

ChIP NCI-H1963_shNONT GSE145028.BRD4.NCI-H1963_shNONT 254 bp overlap

CEBPZ 1 dataset

ChIP GM12878 ENCFF932XBQ 362 bp overlap

ChIP H1 ENCFF991MKH 331 bp overlap

CREB1 2 datasets

ChIP GM12878 ENCFF870CVH 351 bp overlap

ChIP GM23338 ENCFF432ZEW 305 bp overlap

CTBP2 1 dataset

ChIP WA01 ENCSR000EUO.CTBP2.WA01 257 bp overlap

Cebpa 2 datasets

ChIP BLaER1 ENCFF274GAT 251 bp overlap

ChIP BLaER1 ENCFF460KDD 270 bp overlap

E2F6 3 datasets

ChIP H1 ENCFF785DWK 418 bp overlap

ChIP H1 ENCFF785DWK 219 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 233 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 289 bp overlap

FEZF2 2 datasets

Motif DE_24h DE_24h-FEZF2_MA2341.1 8 bp overlap

Motif ES_0h ES_0h-FEZF2_MA2341.1 8 bp overlap

ChIP GM12878 ENCFF157FTE 261 bp overlap

FOXO1::FLI1 1 dataset

Motif ES_0h ES_0h-FOXO1FLI1_MA1956.2 13 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 301 bp overlap

ChIP DE DE-GATA4-2 370 bp overlap

GATA6 8 datasets

ChIP DE DE-GATA6-2 310 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 356 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 267 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 327 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 375 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 305 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 280 bp overlap

ChIP foregut_KO GSE117136.GATA6.foregut_KO 227 bp overlap

HAND2 1 dataset

Motif ES_0h ES_0h-HAND2_MA1638.2 6 bp overlap

HIVEP1 1 dataset

ChIP Hep-G2 ENCSR697WMX.HIVEP1.Hep-G2 243 bp overlap

HNF4A 1 dataset

ChIP Hep-G2 ENCSR469FBY.HNF4A.Hep-G2 70 bp overlap

Motif ES_0h ES_0h-IRF3_MA1418.2 17 bp overlap

Motif ES_0h ES_0h-IRF4_MA1419.2 14 bp overlap

Motif ES_0h ES_0h-IRF7_MA0772.2 13 bp overlap

Motif ES_0h ES_0h-IRF8_MA0652.2 13 bp overlap

Motif ES_0h ES_0h-IRF9_MA0653.1 15 bp overlap

Motif ES_0h ES_0h-Irf1_MA0050.4 11 bp overlap

ChIP ESC S34-ESC-d0-JUN-exp2 266 bp overlap

KDM4A 1 dataset

ChIP WA01 ENCSR000AVC.KDM4A.WA01 253 bp overlap

KDM4C 1 dataset

ChIP KYSE-150 GSE53938.KDM4C.KYSE-150 88 bp overlap

KDM5B 1 dataset

ChIP Hep-G2 ENCSR227MRE.KDM5B.Hep-G2 52 bp overlap

ChIP Hep-G2 ENCSR168DYA.MAX.Hep-G2 171 bp overlap

Motif ES_0h ES_0h-MAZ_MA1522.2 8 bp overlap

ChIP HUVEC-C_siCTL GSE124892.MED1.HUVEC-C_siCTL 385 bp overlap

ChIP P493-6_MST-312 GSE77061.MYC.P493-6_MST-312 139 bp overlap

NANOG 4 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 420 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 134 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 409 bp overlap

ChIP hESC GSE18292.NANOG.hESC 153 bp overlap

NFIC::TLX1 2 datasets

Motif DE_24h DE_24h-NFICTLX1_MA0119.1 14 bp overlap

Motif ES_0h ES_0h-NFICTLX1_MA0119.1 14 bp overlap

Motif ES_0h ES_0h-NFYA_MA0060.4 8 bp overlap

NFYB 5 datasets

Motif ES_0h ES_0h-NFYB_MA0502.3 9 bp overlap

ChIP GM12878 ENCFF474DNH 381 bp overlap

ChIP K-562 ENCSR000EGQ.NFYB.K-562 176 bp overlap

ChIP K562 ENCFF709RXX 317 bp overlap

ChIP WTC11 ENCFF751ZTQ 391 bp overlap

NFYC 2 datasets

Motif ES_0h ES_0h-NFYC_MA1644.2 7 bp overlap

ChIP HepG2 ENCFF836FYP 411 bp overlap

PATZ1 1 dataset

Motif ES_0h ES_0h-PATZ1_MA1961.2 11 bp overlap

Motif ES_0h ES_0h-PBX1_MA0070.2 9 bp overlap

ChIP K562 ENCFF286KMN 405 bp overlap

PBX3 2 datasets

ChIP GM12878 ENCFF285BQQ 160 bp overlap

ChIP SK-N-SH ENCFF876BMC 299 bp overlap

PKNOX1 7 datasets

ChIP GM12878 ENCFF589FCY 436 bp overlap

ChIP GM12878 ENCSR711XNY.PKNOX1.GM12878 423 bp overlap

ChIP HEK293T ENCFF174WDB 164 bp overlap

ChIP K-562 ENCSR115SMW.PKNOX1.K-562 286 bp overlap

ChIP K562 ENCFF236IUS 387 bp overlap

ChIP MCF-7 ENCFF116OCS 202 bp overlap

ChIP MCF-7 ENCSR986XYK.PKNOX1.MCF-7 245 bp overlap

POLR2A 7 datasets

ChIP GM23338 ENCFF450WCS 491 bp overlap

ChIP H1 ENCFF566JSR 557 bp overlap

ChIP H1 ENCFF566JSR 283 bp overlap

ChIP adrenal gland ENCFF843OBJ 305 bp overlap

ChIP adrenal gland ENCFF843OBJ 505 bp overlap

ChIP neural cell ENCFF604SPB 374 bp overlap

ChIP spleen ENCFF044PYR 437 bp overlap

POU2F2 3 datasets

Motif ES_0h ES_0h-POU2F2_MA0507.3 13 bp overlap

ChIP GM12878 ENCFF207RKY 162 bp overlap

ChIP GM12891 ENCFF166YPP 311 bp overlap

POU5F1 1 dataset

ChIP HUES-8 GSE109524.POU5F1.HUES-8 404 bp overlap

RAD21 1 dataset

ChIP HCT-116 GSE131606.RAD21.HCT-116 160 bp overlap

RBBP5 1 dataset

ChIP WA01 ENCSR000AQC.RBBP5.WA01 317 bp overlap

ChIP WA01 GSE104690.RYBP.WA01 234 bp overlap

Motif ES_0h ES_0h-SIX1_MA1118.2 9 bp overlap

Motif ES_0h ES_0h-SIX2_MA1119.2 11 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 360 bp overlap

SMAD3 7 datasets

ChIP BG03_DIFF_2H GSE36578.SMAD3.BG03_DIFF_2H 170 bp overlap

ChIP H69_4TGF GSE145250.SMAD3.H69_4TGF 75 bp overlap

ChIP H69_4TGF GSE145250.SMAD3.H69_4TGF 127 bp overlap

ChIP H69_4Veh GSE145250.SMAD3.H69_4Veh 235 bp overlap

ChIP H69_5TGF GSE145250.SMAD3.H69_5TGF 139 bp overlap

ChIP H69_5Veh GSE145250.SMAD3.H69_5Veh 178 bp overlap

ChIP endoderm GSE29422.SMAD3.endoderm 235 bp overlap

SMAD5 1 dataset

ChIP GM12878 ENCFF178LKN 465 bp overlap

SMARCA4 3 datasets

ChIP CTV-1_DSG GSE128835.SMARCA4.CTV-1_DSG 295 bp overlap

ChIP CTV-1_DSG_SPI1-mut GSE128835.SMARCA4.CTV-1_DSG_SPI1-mut 270 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 169 bp overlap

SMARCC1 1 dataset

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 129 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 327 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 365 bp overlap

ChIP GM12878 ENCFF620LDJ 321 bp overlap

ChIP H1 ENCFF263FUH 102 bp overlap

ChIP WA01 ENCSR000BIR.SP1.WA01 140 bp overlap

ChIP WTC11 ENCFF688PEU 488 bp overlap

ChIP liver ENCFF597LFJ 447 bp overlap

ChIP liver ENCFF769YSM 465 bp overlap

ChIP H1 ENCFF903ACN 377 bp overlap

ChIP H1 ENCFF903ACN 377 bp overlap

SPI1 3 datasets

ChIP CTV-1_delQ GSE128835.SPI1.CTV-1_delQ 242 bp overlap

ChIP GM12878 ENCFF134LCP 297 bp overlap

ChIP primary-monocyte_donorA_ncMO GSE128834.SPI1.primary-monocyte_donorA_ncMO 106 bp overlap

STAT1::STAT2 1 dataset

Motif ES_0h ES_0h-STAT1STAT2_MA0517.2 13 bp overlap

STAT1_pS727 1 dataset

ChIP SET-2 GSE100566.STAT1_pS727.SET-2 434 bp overlap

Stat2 1 dataset

Motif ES_0h ES_0h-Stat2_MA1623.2 10 bp overlap

ChIP H9_MESODERM GSE60606.T.H9_MESODERM 248 bp overlap

ChIP WA01 ENCSR000BHO.TAF1.WA01 117 bp overlap

ChIP H1 ENCFF859IIO 206 bp overlap

ChIP hESC GSE122298.TBP.hESC 108 bp overlap

ChIP hESC_10h GSE122298.TBP.hESC_10h 74 bp overlap

ChIP hESC_2h GSE122298.TBP.hESC_2h 87 bp overlap

TEAD4 1 dataset

ChIP H1 ENCFF778PAX 245 bp overlap

ChIP hESC_DIFF GSE39912.TP53.hESC_DIFF 336 bp overlap

VEZF1 1 dataset

Motif ES_0h ES_0h-VEZF1_MA1578.2 6 bp overlap

ZBTB7B 1 dataset

Motif ES_0h ES_0h-ZBTB7B_MA0694.2 10 bp overlap

ChIP HEK293 ENCFF033NQQ 320 bp overlap

ZNF148 1 dataset

Motif ES_0h ES_0h-ZNF148_MA1653.2 10 bp overlap

ZNF423 1 dataset

ChIP WTC11 ENCFF574PBR 317 bp overlap

ZNF740 1 dataset

Motif ES_0h ES_0h-ZNF740_MA0753.3 10 bp overlap