chr10:95,920,289–95,921,295

chr10 : 95,920,289 – 95,921,295

1,006 bp 99 TFs 7 linked genes

This 1.0 kb open chromatin element is linked to 7 target genes and is bound by 99 transcription factors.

Linked Genes

7 genes

Gene	Expression	Dist. to TSS	Distance	Link type
CC2D2B		12.6 kb	Distal	Multiome
ENTPD1-AS1		12.7 kb	Distal	Multiome
CCNJ		123.0 kb	Distal	Multiome
ENTPD1		164.8 kb	Distal	Multiome
ZNF518A		209.1 kb	Distal	Multiome
TCTN3		226.7 kb	Distal	Multiome
ALDH18A1		263.9 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

99 transcription factors

BRD4 2 datasets

ChIP HEK293_sgNT GSE129407.BRD4.HEK293_sgNT 219 bp overlap

ChIP hESC GSE33281.BRD4.hESC 61 bp overlap

CEBPD 2 datasets

Motif DE_36h DE_36h-CEBPD_MA0836.3 8 bp overlap

Motif DE_48h DE_48h-CEBPD_MA0836.3 8 bp overlap

CTCF 6 datasets

ChIP GM23338 ENCFF772DML 139 bp overlap

ChIP WA01 ENCSR000DLK.CTCF.WA01 120 bp overlap

ChIP endodermal cell ENCFF471YCZ 272 bp overlap

ChIP hiPSC_IB7 GSE106870.CTCF.hiPSC_IB7 171 bp overlap

ChIP hiPSC_IV8 GSE106870.CTCF.hiPSC_IV8 170 bp overlap

ChIP lower leg skin ENCFF414KCF 351 bp overlap

Motif DE_36h DE_36h-Crx_MA0467.3 6 bp overlap

Motif DE_36h DE_36h-DUX4_MA0468.1 11 bp overlap

Motif DE_36h DE_36h-E2F6_MA0471.3 8 bp overlap

Motif DE_36h DE_36h-E2F7_MA0758.1 14 bp overlap

Motif DE_36h DE_36h-EBF3_MA1637.2 9 bp overlap

EOMES 2 datasets

Motif DE_36h DE_36h-EOMES_MA0800.2 9 bp overlap

ChIP hESC GSE26097.EOMES.hESC 355 bp overlap

ESR1 17 datasets

ChIP MCF-7_DMSO GSE125594.ESR1.MCF-7_DMSO 329 bp overlap

ChIP MCF-7_E2 GSE14664.ESR1.MCF-7_E2 115 bp overlap

ChIP MCF-7_E2_45m GSE67295.ESR1.MCF-7_E2_45m 222 bp overlap

ChIP MCF-7_SIGATA_E2 GSE40129.ESR1.MCF-7_SIGATA_E2 156 bp overlap

ChIP MCF-7_TNFa_45m GSE67295.ESR1.MCF-7_TNFa_45m 165 bp overlap

ChIP MCF-7_estradiol-DHT_4h GSE99626.ESR1.MCF-7_estradiol-DHT_4h 217 bp overlap

ChIP MCF-7_estradiol_4h GSE99626.ESR1.MCF-7_estradiol_4h 181 bp overlap

ChIP MCF-7_shTEAD4 GSE125594.ESR1.MCF-7_shTEAD4 215 bp overlap

ChIP MCF-7_shYAP1 GSE125594.ESR1.MCF-7_shYAP1 233 bp overlap

ChIP SUM44PE_ESR1_wildtype GSE100074.ESR1.SUM44PE_ESR1_wildtype 302 bp overlap

ChIP T-47D GSE148277.ESR1.T-47D 712 bp overlap

ChIP T-47D_D538G GSE148277.ESR1.T-47D_D538G 638 bp overlap

ChIP T-47D_D538G_E2 GSE148277.ESR1.T-47D_D538G_E2 848 bp overlap

ChIP T-47D_Y537S GSE148277.ESR1.T-47D_Y537S 746 bp overlap

ChIP T-47D_Y537S_E2 GSE148277.ESR1.T-47D_Y537S_E2 756 bp overlap

ChIP ZR751 ERP000783.ESR1.ZR751 209 bp overlap

ChIP ZR751_E2_TAM ERP000380.ESR1.ZR751_E2_TAM 149 bp overlap

ESR1_Y537C 1 dataset

ChIP SUM44PE__ESR1_mutant_LTED GSE100074.ESR1_Y537C.SUM44PE__ESR1_mutant_LTED 640 bp overlap

ESR1_Y537N 1 dataset

ChIP MCF-7_dox_E2 GSE94493.ESR1_Y537N.MCF-7_dox_E2 186 bp overlap

ESR1_Y537S 2 datasets

ChIP MCF-7_E2 GSE94493.ESR1_Y537S.MCF-7_E2 172 bp overlap

ChIP T-47D_dox GSE94493.ESR1_Y537S.T-47D_dox 268 bp overlap

ESRRB 1 dataset

Motif DE_36h DE_36h-ESRRB_MA0141.4 10 bp overlap

Motif DE_36h DE_36h-Ebf2_MA1604.2 9 bp overlap

Esrrg 1 dataset

Motif DE_36h DE_36h-Esrrg_MA0643.2 9 bp overlap

FIGLA 3 datasets

Motif DE_36h DE_36h-FIGLA_MA0820.2 6 bp overlap

Motif DE_36h DE_36h-FIGLA_MA0820.2 6 bp overlap

Motif DE_36h DE_36h-FIGLA_MA0820.2 6 bp overlap

FOXA1 3 datasets

Motif DE_36h DE_36h-FOXA1_MA0148.5 8 bp overlap

ChIP T-47D_shRNF2_45min GSE137579.FOXA1.T-47D_shRNF2_45min 144 bp overlap

ChIP ZR751_E2_TAM ERP000380.FOXA1.ZR751_E2_TAM 128 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 782 bp overlap

ChIP DE DE-FOXA2-2 685 bp overlap

FOXB1 1 dataset

Motif DE_36h DE_36h-FOXB1_MA0845.1 11 bp overlap

FOXC1 1 dataset

Motif DE_36h DE_36h-FOXC1_MA0032.2 11 bp overlap

FOXC2 1 dataset

Motif DE_36h DE_36h-FOXC2_MA0846.2 11 bp overlap

FOXD2 1 dataset

Motif DE_36h DE_36h-FOXD2_MA0847.4 11 bp overlap

FOXE1 1 dataset

Motif DE_36h DE_36h-FOXE1_MA1487.3 12 bp overlap

FOXF2 1 dataset

Motif DE_36h DE_36h-FOXF2_MA0030.2 9 bp overlap

FOXG1 1 dataset

Motif DE_36h DE_36h-FOXG1_MA0613.1 8 bp overlap

FOXH1 1 dataset

Motif DE_36h DE_36h-FOXH1_MA0479.2 8 bp overlap

FOXK1 1 dataset

Motif DE_36h DE_36h-FOXK1_MA0852.3 7 bp overlap

FOXK2 1 dataset

Motif DE_36h DE_36h-FOXK2_MA1103.3 7 bp overlap

FOXL1 1 dataset

Motif DE_36h DE_36h-FOXL1_MA0033.2 7 bp overlap

FOXO4 1 dataset

Motif DE_36h DE_36h-FOXO4_MA0848.1 7 bp overlap

FOXO6 1 dataset

Motif DE_36h DE_36h-FOXO6_MA0849.1 7 bp overlap

FOXP2 1 dataset

Motif DE_36h DE_36h-FOXP2_MA0593.2 9 bp overlap

FOXP3 1 dataset

Motif DE_36h DE_36h-FOXP3_MA0850.1 7 bp overlap

Foxf1 1 dataset

Motif DE_36h DE_36h-Foxf1_MA1606.2 7 bp overlap

Foxj2 1 dataset

Motif DE_36h DE_36h-Foxj2_MA0614.1 8 bp overlap

Foxo1 1 dataset

Motif DE_36h DE_36h-Foxo1_MA0480.3 7 bp overlap

Foxo3 1 dataset

Motif DE_36h DE_36h-Foxo3_MA0157.4 7 bp overlap

Foxq1 1 dataset

Motif DE_36h DE_36h-Foxq1_MA0040.2 10 bp overlap

GATA4 3 datasets

ChIP DE DE-GATA4-1 676 bp overlap

ChIP DE DE-GATA4-2 688 bp overlap

ChIP foregut GSE117136.GATA4.foregut 81 bp overlap

GATA6 9 datasets

ChIP DE DE-GATA6-1 658 bp overlap

ChIP DE DE-GATA6-2 779 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 377 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 555 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 635 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 531 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 263 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 414 bp overlap

ChIP foregut GSE117136.GATA6.foregut 264 bp overlap

Motif DE_36h DE_36h-GSC_MA0648.2 6 bp overlap

Motif DE_36h DE_36h-GSC2_MA0891.2 6 bp overlap

Gfi1B 1 dataset

Motif DE_36h DE_36h-Gfi1B_MA0483.2 10 bp overlap

HOXC12 1 dataset

Motif DE_36h DE_36h-HOXC12_MA0906.2 10 bp overlap

HOXC13 1 dataset

Motif DE_36h DE_36h-HOXC13_MA0907.2 9 bp overlap

KDM5B 1 dataset

ChIP T-47D GSE46055.KDM5B.T-47D 124 bp overlap

Motif DE_36h DE_36h-MGA_MA0801.1 8 bp overlap

MSANTD3 2 datasets

Motif DE_36h DE_36h-MSANTD3_MA1523.2 7 bp overlap

Motif DE_48h DE_48h-MSANTD3_MA1523.2 7 bp overlap

MYOD1 2 datasets

Motif DE_36h DE_36h-MYOD1_MA0499.3 9 bp overlap

ChIP RD_shSNAI2 GSE137168.MYOD1.RD_shSNAI2 243 bp overlap

Motif DE_36h DE_36h-MZF1_MA0056.3 8 bp overlap

NFATC3 1 dataset

Motif DE_36h DE_36h-NFATC3_MA0625.3 6 bp overlap

Nfatc1 1 dataset

Motif DE_36h DE_36h-Nfatc1_MA0624.3 6 bp overlap

Nr5A2 1 dataset

Motif DE_36h DE_36h-Nr5A2_MA0505.3 9 bp overlap

Motif DE_36h DE_36h-OTX1_MA0711.2 6 bp overlap

Motif DE_36h DE_36h-OTX2_MA0712.3 7 bp overlap

PITX1 1 dataset

Motif DE_36h DE_36h-PITX1_MA0682.3 6 bp overlap

PITX3 1 dataset

Motif DE_36h DE_36h-PITX3_MA0714.2 6 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 575 bp overlap

Ptf1A 2 datasets

Motif DE_36h DE_36h-Ptf1A_MA1620.2 8 bp overlap

Motif DE_36h DE_36h-Ptf1A_MA1620.2 8 bp overlap

RAD21 3 datasets

ChIP H1 ENCFF698EWO 176 bp overlap

ChIP H1 ENCFF967OJF 202 bp overlap

ChIP hiPSC_parental-line GSE106870.RAD21.hiPSC_parental-line 145 bp overlap

Motif DE_36h DE_36h-RARA_MA0729.1 18 bp overlap

Motif DE_36h DE_36h-RBPJ_MA1116.2 6 bp overlap

RELA 3 datasets

ChIP 786-O GSE86092.RELA.786-O 369 bp overlap

ChIP LNCaP_SIFOXA1_TNFA GSE83860.RELA.LNCaP_SIFOXA1_TNFA 57 bp overlap

ChIP MCF-7_Veh GSE67295.RELA.MCF-7_Veh 166 bp overlap

REST 8 datasets

ChIP GM23338 ENCFF024TCL 185 bp overlap

ChIP GM23338 ENCSR871KYB.REST.GM23338 86 bp overlap

ChIP H1 ENCFF429RUE 200 bp overlap

ChIP HEK293 ENCFF073DOT 287 bp overlap

ChIP HEK293 ENCSR896UBV.REST.HEK293 296 bp overlap

ChIP K-562 ENCSR137ZMQ.REST.K-562 175 bp overlap

ChIP K-562 ENCSR000BMW.REST.K-562 104 bp overlap

ChIP WA01 ENCSR000BHM.REST.WA01 176 bp overlap

RHOXF1 1 dataset

Motif DE_36h DE_36h-RHOXF1_MA0719.2 6 bp overlap

RORA 2 datasets

Motif DE_36h DE_36h-RORA_MA0071.1 10 bp overlap

Motif DE_36h DE_36h-RORA_MA0072.2 11 bp overlap

SCRT1 1 dataset

Motif DE_36h DE_36h-SCRT1_MA0743.3 10 bp overlap

SCRT2 1 dataset

Motif DE_36h DE_36h-SCRT2_MA0744.3 10 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 852 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 669 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 318 bp overlap

SMAD2_3 4 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 527 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 755 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 800 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 859 bp overlap

SMARCA4 1 dataset

ChIP TOV-21G GSE110448.SMARCA4.TOV-21G 260 bp overlap

SNAI2 1 dataset

Motif DE_36h DE_36h-SNAI2_MA0745.3 8 bp overlap

SNAI3 1 dataset

Motif DE_36h DE_36h-SNAI3_MA1559.2 9 bp overlap

SOX10 1 dataset

Motif DE_36h DE_36h-SOX10_MA0442.3 6 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 384 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 637 bp overlap

Motif DE_36h DE_36h-SP5_MA1965.2 6 bp overlap

Motif DE_36h DE_36h-TBR1_MA0802.2 9 bp overlap

Motif DE_36h DE_36h-TBX1_MA0805.1 8 bp overlap

TBX15 1 dataset

Motif DE_36h DE_36h-TBX15_MA0803.1 8 bp overlap

TBX18 1 dataset

Motif DE_36h DE_36h-TBX18_MA1565.2 9 bp overlap

Motif DE_36h DE_36h-TBX2_MA0688.2 9 bp overlap

TBX21 1 dataset

Motif DE_36h DE_36h-TBX21_MA0690.3 10 bp overlap

Motif DE_36h DE_36h-TBX3_MA1566.3 9 bp overlap

Motif DE_36h DE_36h-TBX4_MA0806.1 8 bp overlap

Motif DE_36h DE_36h-TBX5_MA0807.1 8 bp overlap

Tbx6 2 datasets

Motif DE_36h DE_36h-Tbx6_MA1567.3 9 bp overlap

Motif DE_36h DE_36h-Tbx6_MA1567.3 9 bp overlap

Motif DE_36h DE_36h-Wt1_MA1627.2 10 bp overlap

ZEB1 3 datasets

Motif DE_36h DE_36h-ZEB1_MA0103.4 6 bp overlap

Motif DE_36h DE_36h-ZEB1_MA0103.4 6 bp overlap

Motif DE_36h DE_36h-ZEB1_MA0103.4 6 bp overlap

ZIC1 2 datasets

Motif DE_36h DE_36h-ZIC1_MA0696.1 14 bp overlap

Motif DE_48h DE_48h-ZIC1_MA0696.1 14 bp overlap

ZKSCAN5 1 dataset

Motif DE_36h DE_36h-ZKSCAN5_MA1652.2 9 bp overlap

ZNF189 2 datasets

Motif DE_36h DE_36h-ZNF189_MA1725.2 9 bp overlap

Motif DE_48h DE_48h-ZNF189_MA1725.2 9 bp overlap

ZNF281 2 datasets

ChIP HepG2 ENCFF585QNU 325 bp overlap

ChIP K562 ENCFF594VNM 471 bp overlap

ZNF341 2 datasets

Motif DE_36h DE_36h-ZNF341_MA1655.2 8 bp overlap

Motif DE_48h DE_48h-ZNF341_MA1655.2 8 bp overlap

ZNF677 2 datasets

Motif DE_36h DE_36h-ZNF677_MA2101.1 12 bp overlap

Motif DE_48h DE_48h-ZNF677_MA2101.1 12 bp overlap

ZNF701 2 datasets

Motif DE_36h DE_36h-ZNF701_MA1987.2 17 bp overlap

Motif DE_48h DE_48h-ZNF701_MA1987.2 17 bp overlap

ZNF740 2 datasets

Motif DE_36h DE_36h-ZNF740_MA0753.3 10 bp overlap

Motif DE_48h DE_48h-ZNF740_MA0753.3 10 bp overlap

ZNF766 1 dataset

Motif DE_36h DE_36h-ZNF766_MA2098.1 9 bp overlap