chr8 : 19,812,489 – 19,812,998

509 bp 75 TFs 1 linked gene

This 509 bp open chromatin element is linked to INTS10 and is bound by 75 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
INTS10		4.4 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

75 transcription factors

AR 1 dataset

ChIP LNCaP GSE80256.AR.LNCaP 192 bp overlap

ATF2 1 dataset

Motif DE_12h DE_12h-ATF2_MA1632.2 10 bp overlap

BCOR 3 datasets

ChIP WA01 GSE104690.BCOR.WA01 357 bp overlap

ChIP WA01_KDM2B_KO GSE104690.BCOR.WA01_KDM2B_KO 366 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 337 bp overlap

CBFA2T2 1 dataset

ChIP NCCIT GSE71675.CBFA2T2.NCCIT 371 bp overlap

CREB1 1 dataset

Motif DE_12h DE_12h-CREB1_MA0018.5 8 bp overlap

CTCF 16 datasets

ChIP A-673 ENCSR611JJS.CTCF.A-673 133 bp overlap

ChIP B-cell ENCSR000AUV.CTCF.B-cell 60 bp overlap

ChIP C4-2B ENCFF821XVN 109 bp overlap

ChIP CD14 ENCSR000ATN.CTCF.CD14 334 bp overlap

ChIP DOHH2 ENCSR084RDK.CTCF.DOHH2 377 bp overlap

ChIP GM04604 GSE148179.CTCF.GM04604 152 bp overlap

ChIP GM04604 GSE148179.CTCF.GM04604 64 bp overlap

ChIP GM12873 ENCFF711LOS 172 bp overlap

ChIP GP5D GSE51234.CTCF.GP5D 87 bp overlap

ChIP HCT-116 GSE131606.CTCF.HCT-116 509 bp overlap

ChIP HT-1080 GSE135580.CTCF.HT-1080 484 bp overlap

ChIP LNCaP-C4-2B ENCSR460LGH.CTCF.LNCaP-C4-2B 132 bp overlap

ChIP MCF-10A GSE98551.CTCF.MCF-10A 307 bp overlap

ChIP keratinocyte GSE154221.CTCF.keratinocyte 509 bp overlap

ChIP neutrophil ENCSR785YRL.CTCF.neutrophil 469 bp overlap

ChIP peripheral-blood-neutrophil_US-1 GSE126755.CTCF.peripheral-blood-neutrophil_US-1 301 bp overlap

CTCFL 1 dataset

Motif DE_12h DE_12h-CTCFL_MA1102.3 8 bp overlap

CTNNB1 1 dataset

ChIP hESC_YAP-_activinA_15h GSE99202.CTNNB1.hESC_YAP-_activinA_15h 383 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF274GAT 293 bp overlap

Creb5 1 dataset

Motif DE_12h DE_12h-Creb5_MA0840.2 10 bp overlap

DBP 1 dataset

Motif DE_12h DE_12h-DBP_MA0639.2 10 bp overlap

DMRT3 1 dataset

Motif DE_12h DE_12h-DMRT3_MA0610.2 7 bp overlap

Dmrt1 2 datasets

Motif DE_12h DE_12h-Dmrt1_MA1603.2 9 bp overlap

EBF1 1 dataset

Motif DE_12h DE_12h-EBF1_MA0154.5 11 bp overlap

EBF3 1 dataset

Motif DE_12h DE_12h-EBF3_MA1637.2 9 bp overlap

EOMES 1 dataset

Motif DE_12h DE_12h-EOMES_MA0800.2 9 bp overlap

ETV1 1 dataset

Motif DE_12h DE_12h-ETV1_MA0761.3 9 bp overlap

EZH2 2 datasets

ChIP DND41 ENCSR000ASW.EZH2.DND41 281 bp overlap

ChIP SU-DHL-5 GSE45982.EZH2.SU-DHL-5 110 bp overlap

Ebf2 1 dataset

Motif DE_12h DE_12h-Ebf2_MA1604.2 9 bp overlap

Ebf4 1 dataset

Motif DE_12h DE_12h-Ebf4_MA2122.1 11 bp overlap

FOSB::JUN 1 dataset

Motif DE_12h DE_12h-FOSBJUN_MA1127.1 11 bp overlap

FOSB::JUNB 1 dataset

Motif DE_12h DE_12h-FOSBJUNB_MA1136.1 10 bp overlap

FOSL1::JUN 1 dataset

Motif DE_12h DE_12h-FOSL1JUN_MA1129.1 10 bp overlap

FOSL1::JUND 1 dataset

Motif DE_12h DE_12h-FOSL1JUND_MA1143.2 9 bp overlap

FOSL2::JUN 1 dataset

Motif DE_12h DE_12h-FOSL2JUN_MA1131.2 10 bp overlap

FOSL2::JUNB 1 dataset

Motif DE_12h DE_12h-FOSL2JUNB_MA1139.2 10 bp overlap

FOSL2::JUND 1 dataset

Motif DE_12h DE_12h-FOSL2JUND_MA1145.2 10 bp overlap

GLIS3 1 dataset

ChIP H9_plus GSE109562.GLIS3.H9_plus 443 bp overlap

HNF4A 1 dataset

Motif DE_12h DE_12h-HNF4A_MA1494.2 14 bp overlap

HOXD11 1 dataset

Motif DE_12h DE_12h-HOXD11_MA0908.2 9 bp overlap

IKZF2 1 dataset

Motif DE_12h DE_12h-IKZF2_MA2326.1 6 bp overlap

Ikzf3 1 dataset

Motif DE_12h DE_12h-Ikzf3_MA1992.2 9 bp overlap

JARID2 1 dataset

ChIP UTEIPS6 GSE48516.JARID2.UTEIPS6 203 bp overlap

JDP2 1 dataset

Motif DE_12h DE_12h-JDP2_MA0656.2 10 bp overlap

JUN 2 datasets

ChIP DE_D1 S40-DE-d1-JUN-exp2 395 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 379 bp overlap

JUN::JUNB 1 dataset

Motif DE_12h DE_12h-JUNJUNB_MA1133.2 11 bp overlap

KLF5 1 dataset

Motif DE_12h DE_12h-KLF5_MA0599.1 10 bp overlap

Lef1 1 dataset

Motif DE_12h DE_12h-Lef1_MA0768.3 8 bp overlap

MEIS1 2 datasets

Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap

NANOG 6 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 351 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 245 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 190 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 509 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 373 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 258 bp overlap

NR1H4::RXRA 1 dataset

Motif DE_12h DE_12h-NR1H4RXRA_MA1146.2 13 bp overlap

NR2F1 1 dataset

Motif DE_12h DE_12h-NR2F1_MA1538.1 15 bp overlap

NR2F6 1 dataset

Motif DE_12h DE_12h-NR2F6_MA1539.1 15 bp overlap

NR4A1 1 dataset

Motif DE_12h DE_12h-NR4A1_MA1112.3 8 bp overlap

NR4A2::RXRA 1 dataset

Motif DE_12h DE_12h-NR4A2RXRA_MA1147.2 13 bp overlap

NRF1 3 datasets

ChIP Hep-G2 ENCSR853ADA.NRF1.Hep-G2 192 bp overlap

ChIP Hep-G2 GSE97661.NRF1.Hep-G2 153 bp overlap

ChIP HepG2 ENCFF694NVY 509 bp overlap

PKNOX1 1 dataset

Motif DE_12h DE_12h-PKNOX1_MA0782.3 10 bp overlap

POU2F1::SOX2 1 dataset

Motif DE_12h DE_12h-POU2F1SOX2_MA1962.1 17 bp overlap

POU3F2 1 dataset

Motif DE_12h DE_12h-POU3F2_MA0787.1 12 bp overlap

POU5F1 4 datasets

ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 454 bp overlap

ChIP hESC ENCSR264RJX.POU5F1.hESC 116 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 321 bp overlap

ChIP hiPSC GSE56567.POU5F1.hiPSC 243 bp overlap

PRDM14 3 datasets

ChIP NCCIT GSE71675.PRDM14.NCCIT 354 bp overlap

ChIP hESC GSE22767.PRDM14.hESC 509 bp overlap

ChIP hESC GSE138674.PRDM14.hESC 362 bp overlap

Pou5f1::Sox2 1 dataset

Motif DE_12h DE_12h-Pou5f1Sox2_MA0142.1 15 bp overlap

RNF2 2 datasets

ChIP WA01 GSE104690.RNF2.WA01 232 bp overlap

ChIP WA09 GSE105028.RNF2.WA09 318 bp overlap

RORA 1 dataset

Motif DE_12h DE_12h-RORA_MA0072.2 11 bp overlap

RORB 1 dataset

Motif DE_12h DE_12h-RORB_MA1150.2 10 bp overlap

RORC 1 dataset

Motif DE_12h DE_12h-RORC_MA1151.2 10 bp overlap

RXRB 1 dataset

Motif DE_12h DE_12h-RXRB_MA1555.1 14 bp overlap

RXRG 1 dataset

Motif DE_12h DE_12h-RXRG_MA1556.1 14 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 285 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 334 bp overlap

SMAD2_3 1 dataset

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 284 bp overlap

SOX2 1 dataset

ChIP hiPSC GSE56567.SOX2.hiPSC 205 bp overlap

SP3 1 dataset

Motif DE_12h DE_12h-SP3_MA0746.3 11 bp overlap

SP5 1 dataset

Motif DE_12h DE_12h-SP5_MA1965.2 6 bp overlap

STAT1 1 dataset

Motif DE_12h DE_12h-STAT1_MA0137.4 9 bp overlap

Stat5a 1 dataset

Motif DE_12h DE_12h-Stat5a_MA1624.2 9 bp overlap

T 1 dataset

ChIP H9_MESODERM GSE60606.T.H9_MESODERM 231 bp overlap

TBX1 1 dataset

Motif DE_12h DE_12h-TBX1_MA0805.1 8 bp overlap

TBX21 1 dataset

Motif DE_12h DE_12h-TBX21_MA0690.3 10 bp overlap

TCF7L2 1 dataset

Motif DE_12h DE_12h-TCF7L2_MA0523.2 9 bp overlap

XRCC5 2 datasets

ChIP K-562 GSE120104.XRCC5.K-562 245 bp overlap

ChIP K-562 ENCSR506KWJ.XRCC5.K-562 223 bp overlap

ZFP14 1 dataset

Motif DE_12h DE_12h-ZFP14_MA1972.1 15 bp overlap

ZKSCAN5 1 dataset

Motif DE_12h DE_12h-ZKSCAN5_MA1652.2 9 bp overlap

ZNF184 1 dataset

Motif DE_12h DE_12h-ZNF184_MA2120.1 13 bp overlap

ZNF354C 1 dataset

Motif DE_12h DE_12h-ZNF354C_MA0130.1 6 bp overlap

ZNF418 1 dataset

Motif DE_12h DE_12h-ZNF418_MA1980.1 15 bp overlap