chr8 : 2,196,983 – 2,198,202
1,219 bp 93 TFs 1 linked gene
This 1.2 kb open chromatin element is linked to KBTBD11 and is bound by 93 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
KBTBD11 224.0 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr8:2,191,983 – 2,203,202
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
93 transcription factors
Source
Cell type
Bach1::Mafk 1 dataset
Motif DE_48h DE_48h-Bach1Mafk_MA0591.2 12 bp overlap
CDX1 1 dataset
Motif DE_48h DE_48h-CDX1_MA0878.3 10 bp overlap
CDX2 1 dataset
Motif DE_48h DE_48h-CDX2_MA0465.3 8 bp overlap
CDX4 1 dataset
Motif DE_48h DE_48h-CDX4_MA1473.2 9 bp overlap
Cebpa 1 dataset
ChIP BLaER1 ENCFF364PUR 319 bp overlap
DMRTC2 1 dataset
Motif DE_48h DE_48h-DMRTC2_MA1479.2 11 bp overlap
EHF 1 dataset
Motif DE_48h DE_48h-EHF_MA0598.4 9 bp overlap
ELF1 3 datasets
Motif DE_48h DE_48h-ELF1_MA0473.4 9 bp overlap
Motif DE_48h DE_48h-ELF1_MA0473.4 9 bp overlap
Motif DE_60h DE_60h-ELF1_MA0473.4 9 bp overlap
ELF3 1 dataset
Motif DE_48h DE_48h-ELF3_MA0640.3 9 bp overlap
EOMES 3 datasets
Motif DE_36h DE_36h-EOMES_MA0800.2 9 bp overlap
Motif DE_48h DE_48h-EOMES_MA0800.2 9 bp overlap
Motif DE_60h DE_60h-EOMES_MA0800.2 9 bp overlap
ERF::FOXO1 1 dataset
Motif DE_48h DE_48h-ERFFOXO1_MA1936.2 12 bp overlap
ETV1 1 dataset
Motif DE_48h DE_48h-ETV1_MA0761.3 9 bp overlap
EZH2 5 datasets
ChIP HCT-116 ENCSR046HGP.EZH2.HCT-116 235 bp overlap
ChIP HCT-116 ENCSR046HGP.EZH2.HCT-116 63 bp overlap
ChIP THP-1 GSE135024.EZH2.THP-1 187 bp overlap
ChIP THP-1 GSE135024.EZH2.THP-1 197 bp overlap
ChIP THP-1 GSE135024.EZH2.THP-1 98 bp overlap
Erg 1 dataset
Motif DE_48h DE_48h-Erg_MA0474.4 10 bp overlap
FIGLA 2 datasets
Motif DE_48h DE_48h-FIGLA_MA0820.2 6 bp overlap
Motif DE_48h DE_48h-FIGLA_MA0820.2 6 bp overlap
FOXA2 4 datasets
ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.FOXA2.BJ1-hTERT_FOXA2_GATA4_Coexp 711 bp overlap
ChIP BJ1-hTERT_GATA4 GSE90454.FOXA2.BJ1-hTERT_GATA4 428 bp overlap
ChIP DE DE-FOXA2-1 726 bp overlap
ChIP DE DE-FOXA2-2 662 bp overlap
FOXB1 4 datasets
Motif DE_48h DE_48h-FOXB1_MA0845.1 11 bp overlap
Motif DE_48h DE_48h-FOXB1_MA0845.1 11 bp overlap
Motif DE_48h DE_48h-FOXB1_MA0845.1 11 bp overlap
Motif DE_48h DE_48h-FOXB1_MA0845.1 11 bp overlap
FOXJ2::ELF1 1 dataset
Motif DE_48h DE_48h-FOXJ2ELF1_MA1952.2 11 bp overlap
GABPA 3 datasets
Motif DE_48h DE_48h-GABPA_MA0062.4 10 bp overlap
Motif DE_48h DE_48h-GABPA_MA0062.4 10 bp overlap
Motif DE_60h DE_60h-GABPA_MA0062.4 10 bp overlap
GATA1 2 datasets
ChIP K-562 GSE107726.GATA1.K-562 316 bp overlap
ChIP K-562_dCas9-LSD1 GSE132212.GATA1.K-562_dCas9-LSD1 258 bp overlap
GATA3 6 datasets
ChIP MCF-7 GSE133072.GATA3.MCF-7 542 bp overlap
ChIP MCF-7 GSE122847.GATA3.MCF-7 506 bp overlap
ChIP MCF-7_sgScr GSE133072.GATA3.MCF-7_sgScr 446 bp overlap
ChIP T-47D_sc GSE122847.GATA3.T-47D_sc 360 bp overlap
ChIP T47D-A1-2_Dex GSE112491.GATA3.T47D-A1-2_Dex 489 bp overlap
ChIP T47D-A1-2_EtOH GSE112491.GATA3.T47D-A1-2_EtOH 496 bp overlap
GATA4 8 datasets
ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.GATA4.BJ1-hTERT_FOXA2_GATA4_Coexp 511 bp overlap
ChIP DE DE-GATA4-1 1031 bp overlap
ChIP DE DE-GATA4-2 1087 bp overlap
Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap
Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap
ChIP cardiomyocyte_5 GSE85628.GATA4.cardiomyocyte_5 195 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 290 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 227 bp overlap
GATA6 11 datasets
ChIP DE DE-GATA6-1 983 bp overlap
ChIP DE DE-GATA6-2 983 bp overlap
Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 774 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 965 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 830 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 1118 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 1004 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 857 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 955 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 232 bp overlap
GRHL1 1 dataset
Motif DE_48h DE_48h-GRHL1_MA0647.2 10 bp overlap
Gata3 1 dataset
Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap
Gmeb1 1 dataset
Motif DE_48h DE_48h-Gmeb1_MA0615.2 6 bp overlap
HOXA10 1 dataset
Motif DE_48h DE_48h-HOXA10_MA0899.2 9 bp overlap
HOXB13 1 dataset
Motif DE_48h DE_48h-HOXB13_MA0901.3 9 bp overlap
HOXD9 1 dataset
Motif DE_48h DE_48h-HOXD9_MA0913.3 9 bp overlap
Hand1 2 datasets
Motif DE_48h DE_48h-Hand1_MA2123.1 9 bp overlap
Motif DE_60h DE_60h-Hand1_MA2123.1 9 bp overlap
Hoxa13 1 dataset
Motif DE_48h DE_48h-Hoxa13_MA0650.4 8 bp overlap
Hoxd13 1 dataset
Motif DE_48h DE_48h-Hoxd13_MA0909.4 7 bp overlap
IKZF2 1 dataset
Motif DE_48h DE_48h-IKZF2_MA2326.1 6 bp overlap
IRF6 3 datasets
Motif DE_36h DE_36h-IRF6_MA1509.1 9 bp overlap
Motif DE_48h DE_48h-IRF6_MA1509.1 9 bp overlap
Motif DE_60h DE_60h-IRF6_MA1509.1 9 bp overlap
Ikzf3 3 datasets
Motif DE_48h DE_48h-Ikzf3_MA1992.2 9 bp overlap
Motif DE_48h DE_48h-Ikzf3_MA1992.2 9 bp overlap
Motif DE_60h DE_60h-Ikzf3_MA1992.2 9 bp overlap
MEF2B 1 dataset
Motif DE_48h DE_48h-MEF2B_MA0660.1 12 bp overlap
MEF2D 1 dataset
Motif DE_48h DE_48h-MEF2D_MA0773.1 12 bp overlap
MEIS1 2 datasets
Motif DE_48h DE_48h-MEIS1_MA0498.3 5 bp overlap
Motif DE_48h DE_48h-MEIS1_MA1639.2 9 bp overlap
MEIS2 1 dataset
Motif DE_48h DE_48h-MEIS2_MA1640.2 9 bp overlap
MGA 3 datasets
Motif DE_36h DE_36h-MGA_MA0801.1 8 bp overlap
Motif DE_48h DE_48h-MGA_MA0801.1 8 bp overlap
Motif DE_60h DE_60h-MGA_MA0801.1 8 bp overlap
MYBL2 1 dataset
ChIP A-673 GSE119971.MYBL2.A-673 123 bp overlap
MYOD1 1 dataset
Motif DE_48h DE_48h-MYOD1_MA0499.3 9 bp overlap
Mafg 1 dataset
Motif DE_48h DE_48h-Mafg_MA0659.4 12 bp overlap
Msgn1 1 dataset
Motif DE_48h DE_48h-Msgn1_MA1524.3 10 bp overlap
PBX2 1 dataset
Motif DE_48h DE_48h-PBX2_MA1113.3 9 bp overlap
PKNOX2 1 dataset
Motif DE_48h DE_48h-PKNOX2_MA0783.1 12 bp overlap
PRDM9 3 datasets
Motif DE_36h DE_36h-PRDM9_MA1723.2 20 bp overlap
Motif DE_48h DE_48h-PRDM9_MA1723.2 20 bp overlap
Motif DE_60h DE_60h-PRDM9_MA1723.2 20 bp overlap
Prdm14 1 dataset
Motif DE_48h DE_48h-Prdm14_MA1998.2 8 bp overlap
Prdm5 1 dataset
Motif DE_48h DE_48h-Prdm5_MA1999.2 11 bp overlap
Ptf1A 1 dataset
Motif DE_48h DE_48h-Ptf1A_MA1620.2 8 bp overlap
RNF2 1 dataset
ChIP A-549 ENCSR798EGJ.RNF2.A-549 200 bp overlap
SMAD2 2 datasets
Motif DE_48h DE_48h-SMAD2_MA1964.2 6 bp overlap
Motif DE_60h DE_60h-SMAD2_MA1964.2 6 bp overlap
SMAD2-3 2 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 589 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 442 bp overlap
SMAD2_3 2 datasets
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 705 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 685 bp overlap
SMARCA4 2 datasets
ChIP J-Lat_GFP-Clone-A72_DMSO GSE100266.SMARCA4.J-Lat_GFP-Clone-A72_DMSO 383 bp overlap
ChIP J-Lat_GFP-Clone-A72_JQ1 GSE100266.SMARCA4.J-Lat_GFP-Clone-A72_JQ1 388 bp overlap
SNAI2 1 dataset
Motif DE_48h DE_48h-SNAI2_MA0745.3 8 bp overlap
SNAI3 1 dataset
Motif DE_48h DE_48h-SNAI3_MA1559.2 9 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 594 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 1091 bp overlap
SP1 3 datasets
Motif DE_36h DE_36h-SP1_MA0079.5 9 bp overlap
Motif DE_48h DE_48h-SP1_MA0079.5 9 bp overlap
Motif DE_60h DE_60h-SP1_MA0079.5 9 bp overlap
SP4 3 datasets
Motif DE_36h DE_36h-SP4_MA0685.2 9 bp overlap
Motif DE_48h DE_48h-SP4_MA0685.2 9 bp overlap
Motif DE_60h DE_60h-SP4_MA0685.2 9 bp overlap
SP5 3 datasets
Motif DE_36h DE_36h-SP5_MA1965.2 6 bp overlap
Motif DE_48h DE_48h-SP5_MA1965.2 6 bp overlap
Motif DE_60h DE_60h-SP5_MA1965.2 6 bp overlap
SREBF1 2 datasets
Motif DE_48h DE_48h-SREBF1_MA0595.1 10 bp overlap
Motif DE_48h DE_48h-SREBF1_MA0829.3 10 bp overlap
SREBF2 1 dataset
Motif DE_48h DE_48h-SREBF2_MA0828.3 10 bp overlap
SUZ12 1 dataset
ChIP Aska-SS GSE108025.SUZ12.Aska-SS 370 bp overlap
TBR1 3 datasets
Motif DE_36h DE_36h-TBR1_MA0802.2 9 bp overlap
Motif DE_48h DE_48h-TBR1_MA0802.2 9 bp overlap
Motif DE_60h DE_60h-TBR1_MA0802.2 9 bp overlap
TBX1 3 datasets
Motif DE_36h DE_36h-TBX1_MA0805.1 8 bp overlap
Motif DE_48h DE_48h-TBX1_MA0805.1 8 bp overlap
Motif DE_60h DE_60h-TBX1_MA0805.1 8 bp overlap
TBX15 3 datasets
Motif DE_36h DE_36h-TBX15_MA0803.1 8 bp overlap
Motif DE_48h DE_48h-TBX15_MA0803.1 8 bp overlap
Motif DE_60h DE_60h-TBX15_MA0803.1 8 bp overlap
TBX18 3 datasets
Motif DE_36h DE_36h-TBX18_MA1565.2 9 bp overlap
Motif DE_48h DE_48h-TBX18_MA1565.2 9 bp overlap
Motif DE_60h DE_60h-TBX18_MA1565.2 9 bp overlap
TBX2 3 datasets
Motif DE_36h DE_36h-TBX2_MA0688.2 9 bp overlap
Motif DE_48h DE_48h-TBX2_MA0688.2 9 bp overlap
Motif DE_60h DE_60h-TBX2_MA0688.2 9 bp overlap
TBX20 3 datasets
Motif DE_36h DE_36h-TBX20_MA0689.1 11 bp overlap
Motif DE_48h DE_48h-TBX20_MA0689.1 11 bp overlap
Motif DE_60h DE_60h-TBX20_MA0689.1 11 bp overlap
TBX21 4 datasets
Motif DE_36h DE_36h-TBX21_MA0690.3 10 bp overlap
Motif DE_48h DE_48h-TBX21_MA0690.3 10 bp overlap
Motif DE_60h DE_60h-TBX21_MA0690.3 10 bp overlap
ChIP Th1_CD3-CD28_donor2 GSE81881.TBX21.Th1_CD3-CD28_donor2 107 bp overlap
TBX3 3 datasets
Motif DE_36h DE_36h-TBX3_MA1566.3 9 bp overlap
Motif DE_48h DE_48h-TBX3_MA1566.3 9 bp overlap
Motif DE_60h DE_60h-TBX3_MA1566.3 9 bp overlap
TBX4 3 datasets
Motif DE_36h DE_36h-TBX4_MA0806.1 8 bp overlap
Motif DE_48h DE_48h-TBX4_MA0806.1 8 bp overlap
Motif DE_60h DE_60h-TBX4_MA0806.1 8 bp overlap
TBX5 3 datasets
Motif DE_36h DE_36h-TBX5_MA0807.1 8 bp overlap
Motif DE_48h DE_48h-TBX5_MA0807.1 8 bp overlap
Motif DE_60h DE_60h-TBX5_MA0807.1 8 bp overlap
TRPS1 1 dataset
Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap
Tbx6 3 datasets
Motif DE_36h DE_36h-Tbx6_MA1567.3 9 bp overlap
Motif DE_48h DE_48h-Tbx6_MA1567.3 9 bp overlap
Motif DE_60h DE_60h-Tbx6_MA1567.3 9 bp overlap
ZEB1 2 datasets
Motif DE_48h DE_48h-ZEB1_MA0103.4 6 bp overlap
Motif DE_48h DE_48h-ZEB1_MA0103.4 6 bp overlap
ZKSCAN3 2 datasets
Motif DE_48h DE_48h-ZKSCAN3_MA1973.2 14 bp overlap
Motif DE_60h DE_60h-ZKSCAN3_MA1973.2 14 bp overlap
ZKSCAN5 3 datasets
Motif DE_36h DE_36h-ZKSCAN5_MA1652.2 9 bp overlap
Motif DE_48h DE_48h-ZKSCAN5_MA1652.2 9 bp overlap
Motif DE_60h DE_60h-ZKSCAN5_MA1652.2 9 bp overlap
ZNF135 3 datasets
Motif DE_36h DE_36h-ZNF135_MA1587.1 14 bp overlap
Motif DE_48h DE_48h-ZNF135_MA1587.1 14 bp overlap
Motif DE_60h DE_60h-ZNF135_MA1587.1 14 bp overlap
ZNF211 1 dataset
Motif DE_48h DE_48h-ZNF211_MA1974.2 10 bp overlap
ZNF324 5 datasets
Motif DE_48h DE_48h-ZNF324_MA1977.2 14 bp overlap
Motif DE_48h DE_48h-ZNF324_MA1977.2 14 bp overlap
Motif DE_48h DE_48h-ZNF324_MA1977.2 14 bp overlap
Motif DE_48h DE_48h-ZNF324_MA1977.2 14 bp overlap
Motif DE_48h DE_48h-ZNF324_MA1977.2 14 bp overlap
ZNF354A 3 datasets
Motif DE_48h DE_48h-ZNF354A_MA1978.2 20 bp overlap
Motif DE_48h DE_48h-ZNF354A_MA1978.2 20 bp overlap
Motif DE_48h DE_48h-ZNF354A_MA1978.2 20 bp overlap
ZNF418 1 dataset
Motif DE_48h DE_48h-ZNF418_MA1980.1 15 bp overlap
ZNF449 2 datasets
Motif DE_48h DE_48h-ZNF449_MA1656.2 10 bp overlap
Motif DE_60h DE_60h-ZNF449_MA1656.2 10 bp overlap
ZNF460 3 datasets
Motif DE_36h DE_36h-ZNF460_MA1596.1 16 bp overlap
Motif DE_48h DE_48h-ZNF460_MA1596.1 16 bp overlap
Motif DE_60h DE_60h-ZNF460_MA1596.1 16 bp overlap
ZNF558 6 datasets
Motif DE_48h DE_48h-ZNF558_MA2335.1 29 bp overlap
Motif DE_48h DE_48h-ZNF558_MA2335.1 29 bp overlap
Motif DE_48h DE_48h-ZNF558_MA2335.1 29 bp overlap
Motif DE_48h DE_48h-ZNF558_MA2335.1 29 bp overlap
Motif DE_48h DE_48h-ZNF558_MA2335.1 29 bp overlap
Motif DE_48h DE_48h-ZNF558_MA2335.1 29 bp overlap
ZNF680 1 dataset
Motif DE_48h DE_48h-ZNF680_MA1729.2 11 bp overlap
ZNF708 1 dataset
Motif DE_48h DE_48h-ZNF708_MA1730.2 9 bp overlap
ZNF770 1 dataset
Motif DE_48h DE_48h-ZNF770_MA2099.1 8 bp overlap
ZSCAN16 1 dataset
ChIP HEK293 GSE76494.ZSCAN16.HEK293 727 bp overlap
Zfp335 3 datasets
Motif DE_36h DE_36h-Zfp335_MA2002.2 7 bp overlap
Motif DE_48h DE_48h-Zfp335_MA2002.2 7 bp overlap
Motif DE_60h DE_60h-Zfp335_MA2002.2 7 bp overlap
Huangfu Lab · Publications · Resources · Contact