chr6:151,456,653–151,457,328

chr6 : 151,456,653 – 151,457,328

675 bp 65 TFs 6 linked genes

This 675 bp open chromatin element is linked to 6 target genes and is bound by 65 transcription factors.

Linked Genes

6 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ARMT1		4.4 kb	Proximal	Proximity
RMND1		4.5 kb	Proximal	Proximity
CCDC170		37.0 kb	Distal	Multiome
ZBTB2		65.5 kb	Distal	Multiome
AKAP12		216.7 kb	Distal	Multiome
MYCT1		1240.8 kb	Distal	Multiome+HiCAR

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

65 transcription factors

ChIP HCT-116 GSE103894.APC.HCT-116 257 bp overlap

ChIP 22Rv1_pLKO GSE109748.AR.22Rv1_pLKO 137 bp overlap

ChIP VCaP_R1881 GSE32892.AR.VCaP_R1881 120 bp overlap

ATF2 4 datasets

ChIP Hep-G2 ENCSR047BUZ.ATF2.Hep-G2 159 bp overlap

ChIP HepG2 ENCFF955VER 176 bp overlap

ChIP K-562 ENCSR869IUD.ATF2.K-562 139 bp overlap

ChIP K562 ENCFF139ZZG 193 bp overlap

BRD4 8 datasets

ChIP HAP1 GSE108387.BRD4.HAP1 293 bp overlap

ChIP HEK293_sgNT GSE129407.BRD4.HEK293_sgNT 305 bp overlap

ChIP K-562_iBET-IFNG GSE138084.BRD4.K-562_iBET-IFNG 187 bp overlap

ChIP MCF-7 GSE55921.BRD4.MCF-7 174 bp overlap

ChIP MCF-7_ARID1A-KO GSE123284.BRD4.MCF-7_ARID1A-KO 675 bp overlap

ChIP MCF-7_ARID1A-KO_4-OHT GSE123284.BRD4.MCF-7_ARID1A-KO_4-OHT 597 bp overlap

ChIP MCF-7_parental GSE123284.BRD4.MCF-7_parental 675 bp overlap

ChIP MCF-7_parental_4-hydroxytamoxifen GSE123284.BRD4.MCF-7_parental_4-hydroxytamoxifen 675 bp overlap

Motif DE_48h DE_48h-CDX1_MA0878.3 10 bp overlap

Motif DE_48h DE_48h-CDX2_MA0465.3 8 bp overlap

Motif DE_48h DE_48h-CDX4_MA1473.2 9 bp overlap

DMRTC2 2 datasets

Motif DE_36h DE_36h-DMRTC2_MA1479.2 11 bp overlap

Motif DE_48h DE_48h-DMRTC2_MA1479.2 11 bp overlap

ChIP ProEs GSE59087.EED.ProEs 166 bp overlap

EOMES 2 datasets

Motif DE_48h DE_48h-EOMES_MA0800.2 9 bp overlap

ChIP hESC GSE26097.EOMES.hESC 295 bp overlap

ERF::SREBF2 1 dataset

Motif DE_48h DE_48h-ERFSREBF2_MA1939.2 16 bp overlap

ESR1_pS118 1 dataset

ChIP MCF-7_Veh_sc GSE117569.ESR1_pS118.MCF-7_Veh_sc 413 bp overlap

FIGLA 1 dataset

Motif DE_48h DE_48h-FIGLA_MA0820.2 6 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 642 bp overlap

ChIP DE DE-FOXA2-2 453 bp overlap

FOXD3 1 dataset

Motif DE_48h DE_48h-FOXD3_MA0041.3 14 bp overlap

GATA4 6 datasets

ChIP DE DE-GATA4-1 508 bp overlap

ChIP DE DE-GATA4-2 551 bp overlap

Motif DE_36h DE_36h-GATA4_MA0482.3 8 bp overlap

Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap

ChIP foregut GSE117136.GATA4.foregut 346 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 247 bp overlap

GATA6 10 datasets

ChIP DE DE-GATA6-1 536 bp overlap

ChIP DE DE-GATA6-2 597 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 395 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 462 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 357 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 549 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 485 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 415 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 330 bp overlap

ChIP foregut GSE117136.GATA6.foregut 407 bp overlap

GRHL2 1 dataset

ChIP LNCaP GSE80256.GRHL2.LNCaP 188 bp overlap

Hoxa13 1 dataset

Motif DE_48h DE_48h-Hoxa13_MA0650.4 8 bp overlap

Hoxd13 1 dataset

Motif DE_48h DE_48h-Hoxd13_MA0909.4 7 bp overlap

ChIP K-562 ENCSR005NMT.ID3.K-562 365 bp overlap

IKZF2 3 datasets

Motif DE_36h DE_36h-IKZF2_MA2326.1 6 bp overlap

Motif DE_48h DE_48h-IKZF2_MA2326.1 6 bp overlap

Motif DE_60h DE_60h-IKZF2_MA2326.1 6 bp overlap

ChIP OCI-AML-3 GSE133516.KAT7.OCI-AML-3 356 bp overlap

MEIS1 2 datasets

Motif DE_36h DE_36h-MEIS1_MA0498.3 5 bp overlap

Motif DE_48h DE_48h-MEIS1_MA0498.3 5 bp overlap

ChIP MCF-7 GSE85317.MEN1.MCF-7 57 bp overlap

MXI1 3 datasets

Motif DE_36h DE_36h-MXI1_MA1108.3 6 bp overlap

Motif DE_48h DE_48h-MXI1_MA1108.3 6 bp overlap

Motif DE_60h DE_60h-MXI1_MA1108.3 6 bp overlap

NCOA1 1 dataset

ChIP MCF-7_E2 ERP000901.NCOA1.MCF-7_E2 175 bp overlap

Nfat5 1 dataset

Motif DE_48h DE_48h-Nfat5_MA0606.3 8 bp overlap

PAX5 4 datasets

ChIP GM12878 ENCFF482PUW 251 bp overlap

ChIP GM12878 ENCSR000BHJ.PAX5.GM12878 162 bp overlap

ChIP GM12878 ENCSR000BHD.PAX5.GM12878 141 bp overlap

ChIP OCI-Ly7 GSE69558.PAX5.OCI-Ly7 275 bp overlap

ChIP EndoC-betaH2 GSE87530.PAX6.EndoC-betaH2 227 bp overlap

PLAG1 3 datasets

Motif DE_36h DE_36h-PLAG1_MA0163.1 14 bp overlap

Motif DE_48h DE_48h-PLAG1_MA0163.1 14 bp overlap

Motif DE_60h DE_60h-PLAG1_MA0163.1 14 bp overlap

POU2F2 3 datasets

Motif DE_36h DE_36h-POU2F2_MA0507.3 13 bp overlap

Motif DE_48h DE_48h-POU2F2_MA0507.3 13 bp overlap

ChIP HNPC_UNDIF GSE74814.POU2F2.HNPC_UNDIF 168 bp overlap

POU3F1 2 datasets

Motif DE_36h DE_36h-POU3F1_MA0786.2 10 bp overlap

Motif DE_48h DE_48h-POU3F1_MA0786.2 10 bp overlap

POU3F2 2 datasets

Motif DE_36h DE_36h-POU3F2_MA0787.1 12 bp overlap

Motif DE_48h DE_48h-POU3F2_MA0787.1 12 bp overlap

POU3F3 2 datasets

Motif DE_36h DE_36h-POU3F3_MA0788.1 13 bp overlap

Motif DE_48h DE_48h-POU3F3_MA0788.1 13 bp overlap

POU5F1 3 datasets

ChIP BJ_INDUCED GSE36570.POU5F1.BJ_INDUCED 133 bp overlap

Motif DE_36h DE_36h-POU5F1_MA1115.2 7 bp overlap

Motif DE_48h DE_48h-POU5F1_MA1115.2 7 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 266 bp overlap

PRDM6 1 dataset

ChIP HEK293 ENCSR892QHR.PRDM6.HEK293 195 bp overlap

Motif DE_36h DE_36h-Pgr_MA2323.1 17 bp overlap

Motif DE_48h DE_48h-Pgr_MA2323.1 17 bp overlap

Pparg::Rxra 1 dataset

Motif DE_48h DE_48h-PpargRxra_MA0065.3 13 bp overlap

REST 2 datasets

Motif DE_48h DE_48h-REST_MA0138.3 20 bp overlap

Motif DE_60h DE_60h-REST_MA0138.3 20 bp overlap

SCRT1 1 dataset

Motif DE_48h DE_48h-SCRT1_MA0743.3 10 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 279 bp overlap

SMAD2_3 1 dataset

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 494 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 220 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 465 bp overlap

Motif DE_48h DE_48h-SP5_MA1965.2 6 bp overlap

ChIP HEK293 ENCSR468IJT.SP7.HEK293 352 bp overlap

Motif DE_48h DE_48h-Sox6_MA0515.1 10 bp overlap

ChIP PRIMA5 GSE33850.TAL1.PRIMA5 152 bp overlap

Motif DE_48h DE_48h-TBR1_MA0802.2 9 bp overlap

TBX20 1 dataset

Motif DE_48h DE_48h-TBX20_MA0689.1 11 bp overlap

TBX21 1 dataset

Motif DE_48h DE_48h-TBX21_MA0690.3 10 bp overlap

Motif DE_48h DE_48h-TBX3_MA1566.3 9 bp overlap

TRIM28 1 dataset

ChIP HEK293 ENCFF582MWI 638 bp overlap

Motif DE_48h DE_48h-Tbx6_MA1567.3 9 bp overlap

Motif DE_48h DE_48h-Wt1_MA1627.2 10 bp overlap

Motif DE_48h DE_48h-ZEB1_MA0103.4 6 bp overlap

ZNF148 1 dataset

Motif DE_48h DE_48h-ZNF148_MA1653.2 10 bp overlap

ZNF281 1 dataset

Motif DE_48h DE_48h-ZNF281_MA1630.3 10 bp overlap

ZNF418 3 datasets

Motif DE_36h DE_36h-ZNF418_MA1980.1 15 bp overlap

Motif DE_48h DE_48h-ZNF418_MA1980.1 15 bp overlap

Motif DE_48h DE_48h-ZNF418_MA1980.1 15 bp overlap

ZNF467 1 dataset

ChIP HEK293 GSE76494.ZNF467.HEK293 151 bp overlap

ZNF675 3 datasets

Motif DE_36h DE_36h-ZNF675_MA1714.2 19 bp overlap

Motif DE_48h DE_48h-ZNF675_MA1714.2 19 bp overlap

Motif DE_60h DE_60h-ZNF675_MA1714.2 19 bp overlap

ZNF682 3 datasets

Motif DE_36h DE_36h-ZNF682_MA1599.2 11 bp overlap

Motif DE_48h DE_48h-ZNF682_MA1599.2 11 bp overlap

Motif DE_60h DE_60h-ZNF682_MA1599.2 11 bp overlap

ZNF85 1 dataset

ChIP HEK293 GSE76494.ZNF85.HEK293 140 bp overlap