chr5 : 93,422,023 – 93,422,556

533 bp 85 TFs 1 linked gene

This 533 bp open chromatin element is linked to NR2F1-AS1 and is bound by 85 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
NR2F1-AS1		at TSS	At TSS	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

85 transcription factors

ARID2 1 dataset

ChIP BIN-67_ctrl GSE117734.ARID2.BIN-67_ctrl 210 bp overlap

ASH2L 2 datasets

ChIP H1 ENCFF399KAM 533 bp overlap

ChIP WA01 ENCSR850KIP.ASH2L.WA01 494 bp overlap

ATF2 2 datasets

ChIP H1 ENCFF295GZO 373 bp overlap

ChIP H1 ENCFF295GZO 526 bp overlap

Ahr::Arnt 2 datasets

Motif DE_12h DE_12h-AhrArnt_MA0006.2 5 bp overlap

Motif ES_0h ES_0h-AhrArnt_MA0006.2 5 bp overlap

Atf3 2 datasets

Motif DE_12h DE_12h-Atf3_MA1988.2 7 bp overlap

Motif ES_0h ES_0h-Atf3_MA1988.2 7 bp overlap

BACH1 2 datasets

Motif DE_12h DE_12h-BACH1_MA1633.2 9 bp overlap

Motif ES_0h ES_0h-BACH1_MA1633.2 9 bp overlap

BACH2 2 datasets

Motif DE_12h DE_12h-BACH2_MA1101.3 11 bp overlap

Motif ES_0h ES_0h-BACH2_MA1101.3 11 bp overlap

BATF 2 datasets

Motif DE_12h DE_12h-BATF_MA1634.2 7 bp overlap

Motif ES_0h ES_0h-BATF_MA1634.2 7 bp overlap

BATF3 2 datasets

Motif DE_12h DE_12h-BATF3_MA0835.3 7 bp overlap

Motif ES_0h ES_0h-BATF3_MA0835.3 7 bp overlap

BATF::JUN 2 datasets

Motif DE_12h DE_12h-BATFJUN_MA0462.3 7 bp overlap

Motif ES_0h ES_0h-BATFJUN_MA0462.3 7 bp overlap

BCOR 1 dataset

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 156 bp overlap

BNC2 2 datasets

Motif DE_12h DE_12h-BNC2_MA1928.2 7 bp overlap

Motif ES_0h ES_0h-BNC2_MA1928.2 7 bp overlap

BRD4 5 datasets

ChIP NCI-H1963_shASXL3 GSE145028.BRD4.NCI-H1963_shASXL3 63 bp overlap

ChIP cortical-interneuron_KCl-pos_JQ1-neg GSE117508.BRD4.cortical-interneuron_KCl-pos_JQ1-neg 388 bp overlap

ChIP cortical-interneuron_R133C_KCl-neg_JQ1-neg GSE117508.BRD4.cortical-interneuron_R133C_KCl-neg_JQ1-neg 414 bp overlap

ChIP cortical-interneuron_R133C_KCl-neg_JQ1-pos GSE117508.BRD4.cortical-interneuron_R133C_KCl-neg_JQ1-pos 394 bp overlap

ChIP cortical-interneuron_R133C_KCl-pos_JQ1-neg GSE117508.BRD4.cortical-interneuron_R133C_KCl-pos_JQ1-neg 406 bp overlap

CBFA2T2 1 dataset

ChIP NCCIT GSE71675.CBFA2T2.NCCIT 225 bp overlap

CHD2 2 datasets

ChIP SK-N-SH ENCFF669KMB 222 bp overlap

ChIP SK-N-SH ENCSR274SLQ.CHD2.SK-N-SH 138 bp overlap

CHD7 1 dataset

ChIP hiPSC_derived_lt-NES GSE108506.CHD7.hiPSC_derived_lt-NES 392 bp overlap

CTCF 2 datasets

Motif DE_12h DE_12h-CTCF_MA1929.2 31 bp overlap

Motif ES_0h ES_0h-CTCF_MA1929.2 31 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF335XTP 368 bp overlap

ELF3 3 datasets

ChIP PDAC GSE64557.ELF3.PDAC 263 bp overlap

ChIP PDAC_KOKLF5 GSE64557.ELF3.PDAC_KOKLF5 297 bp overlap

ChIP PDAC_SHCTR GSE64557.ELF3.PDAC_SHCTR 267 bp overlap

EP300 3 datasets

ChIP SK-N-SH ENCFF829RWA 201 bp overlap

ChIP SK-N-SH ENCSR000EHV.EP300.SK-N-SH 175 bp overlap

ChIP neural ENCSR843ZUP.EP300.neural 142 bp overlap

ERG 1 dataset

ChIP AMLPZ12 GSE23730.ERG.AMLPZ12 121 bp overlap

ESR1 2 datasets

ChIP Ishikawa_DMSO_D538G_clone3 GSE132426.ESR1.Ishikawa_DMSO_D538G_clone3 221 bp overlap

ChIP primary-endometrium-cancer_E1_DSG GSE114737.ESR1.primary-endometrium-cancer_E1_DSG 168 bp overlap

ETV2::FIGLA 1 dataset

Motif DE_12h DE_12h-ETV2FIGLA_MA1941.2 13 bp overlap

ETV5::FIGLA 1 dataset

Motif DE_12h DE_12h-ETV5FIGLA_MA1945.2 14 bp overlap

EWSR1-FLI1 1 dataset

Motif DE_12h DE_12h-EWSR1-FLI1_MA0149.1 18 bp overlap

EZH2 2 datasets

ChIP LNCaP-abl GSE39459.EZH2.LNCaP-abl 270 bp overlap

ChIP RH30_DMSO GSE85169.EZH2.RH30_DMSO 216 bp overlap

FOS 2 datasets

Motif DE_12h DE_12h-FOS_MA0476.2 8 bp overlap

Motif ES_0h ES_0h-FOS_MA0476.2 8 bp overlap

FOS::JUN 2 datasets

Motif DE_12h DE_12h-FOSJUN_MA0099.4 9 bp overlap

Motif ES_0h ES_0h-FOSJUN_MA0099.4 9 bp overlap

FOS::JUNB 2 datasets

Motif DE_12h DE_12h-FOSJUNB_MA1134.2 9 bp overlap

Motif ES_0h ES_0h-FOSJUNB_MA1134.2 9 bp overlap

FOS::JUND 2 datasets

Motif DE_12h DE_12h-FOSJUND_MA1141.2 9 bp overlap

Motif ES_0h ES_0h-FOSJUND_MA1141.2 9 bp overlap

FOSB::JUNB 2 datasets

Motif DE_12h DE_12h-FOSBJUNB_MA1135.2 9 bp overlap

Motif ES_0h ES_0h-FOSBJUNB_MA1135.2 9 bp overlap

FOSL1 2 datasets

Motif DE_12h DE_12h-FOSL1_MA0477.3 9 bp overlap

Motif ES_0h ES_0h-FOSL1_MA0477.3 9 bp overlap

FOSL1::JUN 2 datasets

Motif DE_12h DE_12h-FOSL1JUN_MA1128.2 9 bp overlap

Motif ES_0h ES_0h-FOSL1JUN_MA1128.2 9 bp overlap

FOSL2 2 datasets

Motif DE_12h DE_12h-FOSL2_MA0478.2 10 bp overlap

Motif ES_0h ES_0h-FOSL2_MA0478.2 10 bp overlap

FOSL2::JUN 2 datasets

Motif DE_12h DE_12h-FOSL2JUN_MA1130.2 9 bp overlap

Motif ES_0h ES_0h-FOSL2JUN_MA1130.2 9 bp overlap

FOSL2::JUNB 2 datasets

Motif DE_12h DE_12h-FOSL2JUNB_MA1138.2 9 bp overlap

Motif ES_0h ES_0h-FOSL2JUNB_MA1138.2 9 bp overlap

FOSL2::JUND 2 datasets

Motif DE_12h DE_12h-FOSL2JUND_MA1144.2 9 bp overlap

Motif ES_0h ES_0h-FOSL2JUND_MA1144.2 9 bp overlap

FOXA2 1 dataset

ChIP PANC-1_HNF1B-OE GSE119930.FOXA2.PANC-1_HNF1B-OE 118 bp overlap

GATA2 5 datasets

ChIP SH-SY5Y ENCFF485YIB 234 bp overlap

ChIP SH-SY5Y ENCSR000EYB.GATA2.SH-SY5Y 432 bp overlap

ChIP SK-N-SH ENCFF764OZD 148 bp overlap

ChIP SK-N-SH ENCSR706VOO.GATA2.SK-N-SH 342 bp overlap

ChIP hiPSC_SLC6ebs GSE107639.GATA2.hiPSC_SLC6ebs 182 bp overlap

GATA3 6 datasets

ChIP BE2C GSE65664.GATA3.BE2C 139 bp overlap

ChIP NGP GSE65664.GATA3.NGP 121 bp overlap

ChIP SH-SY5Y ENCFF475HYF 84 bp overlap

ChIP SH-SY5Y ENCSR000EXZ.GATA3.SH-SY5Y 264 bp overlap

ChIP SH-SY5Y GSE65664.GATA3.SH-SY5Y 158 bp overlap

ChIP SK-N-SH ENCFF040SSB 226 bp overlap

GATA3_Nter 1 dataset

ChIP T-47D_CR3flp GSE99479.GATA3_Nter.T-47D_CR3flp 221 bp overlap

HAND2 1 dataset

ChIP CLB-Ga GSE90683.HAND2.CLB-Ga 250 bp overlap

HMGB2 1 dataset

ChIP HUVEC-C GSE98245.HMGB2.HUVEC-C 386 bp overlap

HNF1B 1 dataset

ChIP PANC-1_HNF1B-OE GSE119930.HNF1B.PANC-1_HNF1B-OE 110 bp overlap

IKZF2 1 dataset

Motif DE_12h DE_12h-IKZF2_MA2326.1 6 bp overlap

ISL2 2 datasets

Motif DE_12h DE_12h-ISL2_MA0914.2 6 bp overlap

Motif ES_0h ES_0h-ISL2_MA0914.2 6 bp overlap

JARID2 1 dataset

ChIP MRC-5_IPS25_MEG3 GSE48515.JARID2.MRC-5_IPS25_MEG3 228 bp overlap

JUN 1 dataset

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 344 bp overlap

JUN::JUNB 2 datasets

Motif DE_12h DE_12h-JUNJUNB_MA1132.2 8 bp overlap

Motif ES_0h ES_0h-JUNJUNB_MA1132.2 8 bp overlap

JUNB 2 datasets

Motif DE_12h DE_12h-JUNB_MA0490.3 9 bp overlap

Motif ES_0h ES_0h-JUNB_MA0490.3 9 bp overlap

JUND 2 datasets

Motif DE_12h DE_12h-JUND_MA0491.3 9 bp overlap

Motif ES_0h ES_0h-JUND_MA0491.3 9 bp overlap

Jun 2 datasets

Motif DE_12h DE_12h-Jun_MA0489.3 8 bp overlap

Motif ES_0h ES_0h-Jun_MA0489.3 8 bp overlap

KDM1A 1 dataset

ChIP SH-SY5Y_B3 GSE58258.KDM1A.SH-SY5Y_B3 298 bp overlap

MAFK 2 datasets

Motif DE_12h DE_12h-MAFK_MA0496.4 10 bp overlap

Motif ES_0h ES_0h-MAFK_MA0496.4 10 bp overlap

MXI1 2 datasets

ChIP SK-N-SH ENCFF746HVJ 321 bp overlap

ChIP SK-N-SH ENCSR000EIA.MXI1.SK-N-SH 125 bp overlap

MYCN 3 datasets

ChIP CHP-134 GSE129588.MYCN.CHP-134 164 bp overlap

ChIP LA-N-5 GSE138295.MYCN.LA-N-5 406 bp overlap

ChIP NB-1643 GSE94782.MYCN.NB-1643 75 bp overlap

NANOG 2 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 477 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 117 bp overlap

Nkx3-2 2 datasets

Motif DE_12h DE_12h-Nkx3-2_MA0122.4 10 bp overlap

Motif ES_0h ES_0h-Nkx3-2_MA0122.4 10 bp overlap

PCGF1 1 dataset

ChIP HEK293T_PCGF135fl GSE119618.PCGF1.HEK293T_PCGF135fl 75 bp overlap

PHIP 1 dataset

ChIP HEK293_ab833 GSE101646.PHIP.HEK293_ab833 248 bp overlap

PITX3 1 dataset

ChIP SH-SY5Y GSE93275.PITX3.SH-SY5Y 503 bp overlap

RAD21 1 dataset

ChIP SK-N-SH ENCFF747MAS 107 bp overlap

RBBP5 1 dataset

ChIP WA01 ENCSR000AQC.RBBP5.WA01 113 bp overlap

RBPJ 1 dataset

ChIP GSC8-11_dasatinib GSE74557.RBPJ.GSC8-11_dasatinib 285 bp overlap

RCOR1 2 datasets

ChIP SK-N-SH ENCFF518EXB 139 bp overlap

ChIP SK-N-SH ENCSR009TKN.RCOR1.SK-N-SH 319 bp overlap

REST 1 dataset

ChIP neural ENCSR000BTV.REST.neural 159 bp overlap

SIN3A 1 dataset

ChIP WA01 ENCSR000EBO.SIN3A.WA01 121 bp overlap

SMARCA4 6 datasets

ChIP BIN-67_lentivirus-SMARCA4-K785R GSE117734.SMARCA4.BIN-67_lentivirus-SMARCA4-K785R 203 bp overlap

ChIP NGP GSE134626.SMARCA4.NGP 254 bp overlap

ChIP NGP_ARID1A-het GSE134626.SMARCA4.NGP_ARID1A-het 277 bp overlap

ChIP NPC_siCT GSE122631.SMARCA4.NPC_siCT 222 bp overlap

ChIP NSC GSE125033.SMARCA4.NSC 507 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 469 bp overlap

SMARCB1 3 datasets

ChIP hiPSC GSE124903.SMARCB1.hiPSC 161 bp overlap

ChIP hiPSC GSE124903.SMARCB1.hiPSC 205 bp overlap

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 203 bp overlap

SMARCC1 4 datasets

ChIP BIN-67_lentivirus-SMARCA4-K785R GSE117734.SMARCC1.BIN-67_lentivirus-SMARCA4-K785R 212 bp overlap

ChIP SCCOHT-1 GSE117734.SMARCC1.SCCOHT-1 353 bp overlap

ChIP hiPSC GSE124903.SMARCC1.hiPSC 329 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 460 bp overlap

SNAI2 1 dataset

ChIP RD GSE137168.SNAI2.RD 285 bp overlap

SOX2 1 dataset

ChIP HNSC GSE69479.SOX2.HNSC 525 bp overlap

TCF7L1 1 dataset

Motif DE_12h DE_12h-TCF7L1_MA1421.1 12 bp overlap

TFAP4::ETV1 1 dataset

Motif DE_12h DE_12h-TFAP4ETV1_MA1966.2 13 bp overlap

TRIM28 1 dataset

ChIP WIBR3_NAIVE GSE84382.TRIM28.WIBR3_NAIVE 352 bp overlap

TWIST1 2 datasets

ChIP BE2C GSE80151.TWIST1.BE2C 188 bp overlap

ChIP SK-N-BE2-C GSE80151.TWIST1.SK-N-BE2-C 188 bp overlap

Wt1 1 dataset

Motif DE_12h DE_12h-Wt1_MA1627.2 10 bp overlap

YY1 2 datasets

ChIP H1 ENCFF524BTL 337 bp overlap

ChIP WA01 ENCSR000BKD.YY1.WA01 168 bp overlap

ZFP42 1 dataset

Motif DE_12h DE_12h-ZFP42_MA1651.2 13 bp overlap

ZKSCAN1 1 dataset

Motif DE_12h DE_12h-ZKSCAN1_MA1585.2 9 bp overlap

ZKSCAN5 2 datasets

Motif DE_12h DE_12h-ZKSCAN5_MA1652.2 9 bp overlap

Motif ES_0h ES_0h-ZKSCAN5_MA1652.2 9 bp overlap

ZNF490 1 dataset

ChIP HEK293 GSE76494.ZNF490.HEK293 268 bp overlap

ZNF550 1 dataset

ChIP Hep-G2 ENCSR198BHH.ZNF550.Hep-G2 221 bp overlap

ZNF786 1 dataset

ChIP HEK293T GSE78099.ZNF786.HEK293T 262 bp overlap

ZSCAN21 2 datasets

Motif DE_12h DE_12h-ZSCAN21_MA2336.1 7 bp overlap

Motif ES_0h ES_0h-ZSCAN21_MA2336.1 7 bp overlap