chr5 : 16,378,323 – 16,379,199
876 bp 110 TFs 4 linked genes
This 876 bp open chromatin element is linked to 4 target genes and is bound by 110 transcription factors.
Linked Genes
4 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
ENSG00000249737 49.6 kb Distal Multiome
ZNF622 86.9 kb Distal Multiome
MARCHF11 199.1 kb Distal Multiome
RETREG1 238.0 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr5:16,373,323 – 16,384,199
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
110 transcription factors
Source
Cell type
ASCL1 3 datasets
ChIP NCI-H889 GSE69394.ASCL1.NCI-H889 128 bp overlap
ChIP SCLC_ASCLP GSE61197.ASCL1.SCLC_ASCLP 140 bp overlap
ChIP SCLC_ASCLP_NE GSE61197.ASCL1.SCLC_ASCLP_NE 145 bp overlap
Atoh1 2 datasets
Motif DE_60h DE_60h-Atoh1_MA0461.3 8 bp overlap
Motif DE_72h DE_72h-Atoh1_MA0461.3 8 bp overlap
BHLHE23 2 datasets
Motif DE_60h DE_60h-BHLHE23_MA0817.2 10 bp overlap
Motif DE_72h DE_72h-BHLHE23_MA0817.2 10 bp overlap
BRD1 1 dataset
ChIP RKO GSE47190.BRD1.RKO 119 bp overlap
Cebpa 1 dataset
ChIP BLaER1 ENCFF335XTP 273 bp overlap
Crx 2 datasets
Motif DE_60h DE_60h-Crx_MA0467.3 6 bp overlap
Motif DE_72h DE_72h-Crx_MA0467.3 6 bp overlap
DPRX 2 datasets
Motif DE_60h DE_60h-DPRX_MA1480.2 9 bp overlap
Motif DE_72h DE_72h-DPRX_MA1480.2 9 bp overlap
ESRRA 2 datasets
Motif DE_60h DE_60h-ESRRA_MA0592.4 9 bp overlap
Motif DE_72h DE_72h-ESRRA_MA0592.4 9 bp overlap
ESRRB 2 datasets
Motif DE_60h DE_60h-ESRRB_MA0141.4 10 bp overlap
Motif DE_72h DE_72h-ESRRB_MA0141.4 10 bp overlap
ESRRG 1 dataset
ChIP cardiomyocyte GSE113760.ESRRG.cardiomyocyte 781 bp overlap
ETS1 1 dataset
ChIP cardiomyocyte_D9 GSE129986.ETS1.cardiomyocyte_D9 462 bp overlap
EZH2 1 dataset
ChIP THP-1 GSE135024.EZH2.THP-1 336 bp overlap
EZH2_phosphoT487 1 dataset
ChIP PC-9 ENCSR702GMW.EZH2_phosphoT487.PC-9 291 bp overlap
Esrrg 2 datasets
Motif DE_60h DE_60h-Esrrg_MA0643.2 9 bp overlap
Motif DE_72h DE_72h-Esrrg_MA0643.2 9 bp overlap
FEZF2 2 datasets
Motif DE_60h DE_60h-FEZF2_MA2341.1 8 bp overlap
Motif DE_72h DE_72h-FEZF2_MA2341.1 8 bp overlap
FIGLA 2 datasets
Motif DE_60h DE_60h-FIGLA_MA0820.2 6 bp overlap
Motif DE_72h DE_72h-FIGLA_MA0820.2 6 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 620 bp overlap
ChIP DE DE-FOXA2-2 638 bp overlap
GATA1::TAL1 2 datasets
Motif DE_60h DE_60h-GATA1TAL1_MA0140.3 17 bp overlap
Motif DE_72h DE_72h-GATA1TAL1_MA0140.3 17 bp overlap
GATA4 12 datasets
ChIP DE DE-GATA4-1 542 bp overlap
ChIP DE DE-GATA4-2 603 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap
ChIP G296S GSE85628.GATA4.G296S 338 bp overlap
ChIP G296S_2 GSE85628.GATA4.G296S_2 338 bp overlap
ChIP cardiomyocyte GSE85628.GATA4.cardiomyocyte 258 bp overlap
ChIP cardiomyocyte_1 GSE85628.GATA4.cardiomyocyte_1 268 bp overlap
ChIP cardiomyocyte_5 GSE85628.GATA4.cardiomyocyte_5 289 bp overlap
ChIP cardiomyocyte_7 GSE85628.GATA4.cardiomyocyte_7 418 bp overlap
ChIP foregut GSE117136.GATA4.foregut 399 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 278 bp overlap
GATA5 2 datasets
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
Motif DE_72h DE_72h-GATA5_MA0766.3 8 bp overlap
GATA6 6 datasets
ChIP DE DE-GATA6-1 583 bp overlap
ChIP DE DE-GATA6-2 643 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 301 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 380 bp overlap
ChIP foregut GSE117136.GATA6.foregut 403 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 240 bp overlap
GSC 2 datasets
Motif DE_60h DE_60h-GSC_MA0648.2 6 bp overlap
Motif DE_72h DE_72h-GSC_MA0648.2 6 bp overlap
GSC2 2 datasets
Motif DE_60h DE_60h-GSC2_MA0891.2 6 bp overlap
Motif DE_72h DE_72h-GSC2_MA0891.2 6 bp overlap
Gli1 2 datasets
Motif DE_60h DE_60h-Gli1_MA1990.2 10 bp overlap
Motif DE_72h DE_72h-Gli1_MA1990.2 10 bp overlap
Gli2 2 datasets
Motif DE_60h DE_60h-Gli2_MA0734.4 9 bp overlap
Motif DE_72h DE_72h-Gli2_MA0734.4 9 bp overlap
HEY2 1 dataset
ChIP hiPSC GSE81585.HEY2.hiPSC 259 bp overlap
Hnf1A 2 datasets
Motif DE_60h DE_60h-Hnf1A_MA1991.2 10 bp overlap
Motif DE_72h DE_72h-Hnf1A_MA1991.2 10 bp overlap
ISL2 2 datasets
Motif DE_60h DE_60h-ISL2_MA0914.2 6 bp overlap
Motif DE_72h DE_72h-ISL2_MA0914.2 6 bp overlap
JUN 1 dataset
ChIP 786-O GSE86092.JUN.786-O 177 bp overlap
KDM5B 1 dataset
ChIP HCC2157 GSE46055.KDM5B.HCC2157 117 bp overlap
KLF17 2 datasets
Motif DE_60h DE_60h-KLF17_MA1514.2 14 bp overlap
Motif DE_72h DE_72h-KLF17_MA1514.2 14 bp overlap
KLF9 2 datasets
Motif DE_60h DE_60h-KLF9_MA1107.3 11 bp overlap
Motif DE_72h DE_72h-KLF9_MA1107.3 11 bp overlap
MED1 2 datasets
ChIP G296S GSE85628.MED1.G296S 296 bp overlap
ChIP G296S_2 GSE85628.MED1.G296S_2 296 bp overlap
MEIS1 2 datasets
Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap
Motif DE_72h DE_72h-MEIS1_MA0498.3 5 bp overlap
MEIS2 2 datasets
Motif DE_60h DE_60h-MEIS2_MA0774.1 8 bp overlap
Motif DE_72h DE_72h-MEIS2_MA0774.1 8 bp overlap
MEIS3 2 datasets
Motif DE_60h DE_60h-MEIS3_MA0775.2 7 bp overlap
Motif DE_72h DE_72h-MEIS3_MA0775.2 7 bp overlap
MITF 1 dataset
ChIP melanocyte_BRAFV600E GSE50681.MITF.melanocyte_BRAFV600E 210 bp overlap
MYOD1 2 datasets
Motif DE_60h DE_60h-MYOD1_MA0499.3 9 bp overlap
Motif DE_72h DE_72h-MYOD1_MA0499.3 9 bp overlap
NCOA3 1 dataset
ChIP MCF-7_E2 ERP000901.NCOA3.MCF-7_E2 150 bp overlap
NEUROG1 2 datasets
Motif DE_60h DE_60h-NEUROG1_MA0623.2 10 bp overlap
Motif DE_72h DE_72h-NEUROG1_MA0623.2 10 bp overlap
NEUROG2 2 datasets
Motif DE_60h DE_60h-NEUROG2_MA0669.1 10 bp overlap
Motif DE_72h DE_72h-NEUROG2_MA0669.1 10 bp overlap
NFIA 2 datasets
Motif DE_60h DE_60h-NFIA_MA0670.2 6 bp overlap
Motif DE_72h DE_72h-NFIA_MA0670.2 6 bp overlap
NFIB 2 datasets
Motif DE_60h DE_60h-NFIB_MA1643.2 17 bp overlap
Motif DE_72h DE_72h-NFIB_MA1643.2 17 bp overlap
NFIC 2 datasets
Motif DE_60h DE_60h-NFIC_MA1527.2 15 bp overlap
Motif DE_72h DE_72h-NFIC_MA1527.2 15 bp overlap
NFIC::TLX1 2 datasets
Motif DE_60h DE_60h-NFICTLX1_MA0119.1 14 bp overlap
Motif DE_72h DE_72h-NFICTLX1_MA0119.1 14 bp overlap
NFIX 4 datasets
Motif DE_60h DE_60h-NFIX_MA0671.2 6 bp overlap
Motif DE_60h DE_60h-NFIX_MA1528.2 14 bp overlap
Motif DE_72h DE_72h-NFIX_MA0671.2 6 bp overlap
Motif DE_72h DE_72h-NFIX_MA1528.2 14 bp overlap
NKX2-5 2 datasets
ChIP hESC_ab3584 GSE89457.NKX2-5.hESC_ab3584 542 bp overlap
ChIP hESC_sc-14033 GSE89457.NKX2-5.hESC_sc-14033 342 bp overlap
NR1H4::RXRA 2 datasets
Motif DE_60h DE_60h-NR1H4RXRA_MA1146.2 13 bp overlap
Motif DE_72h DE_72h-NR1H4RXRA_MA1146.2 13 bp overlap
NR1I2 2 datasets
Motif DE_60h DE_60h-NR1I2_MA1533.2 15 bp overlap
Motif DE_72h DE_72h-NR1I2_MA1533.2 15 bp overlap
NR1I3 2 datasets
Motif DE_60h DE_60h-NR1I3_MA1534.2 8 bp overlap
Motif DE_72h DE_72h-NR1I3_MA1534.2 8 bp overlap
NR2C1 2 datasets
Motif DE_60h DE_60h-NR2C1_MA1535.2 6 bp overlap
Motif DE_72h DE_72h-NR2C1_MA1535.2 6 bp overlap
NR2C2 2 datasets
Motif DE_60h DE_60h-NR2C2_MA1536.2 6 bp overlap
Motif DE_72h DE_72h-NR2C2_MA1536.2 6 bp overlap
NR2F1 2 datasets
Motif DE_60h DE_60h-NR2F1_MA0017.3 12 bp overlap
Motif DE_72h DE_72h-NR2F1_MA0017.3 12 bp overlap
NR2F2 2 datasets
Motif DE_60h DE_60h-NR2F2_MA1111.2 7 bp overlap
Motif DE_72h DE_72h-NR2F2_MA1111.2 7 bp overlap
NR4A1 2 datasets
Motif DE_60h DE_60h-NR4A1_MA1112.3 8 bp overlap
Motif DE_72h DE_72h-NR4A1_MA1112.3 8 bp overlap
NR4A2 2 datasets
Motif DE_60h DE_60h-NR4A2_MA0160.3 8 bp overlap
Motif DE_72h DE_72h-NR4A2_MA0160.3 8 bp overlap
NR5A1 2 datasets
Motif DE_60h DE_60h-NR5A1_MA1540.3 12 bp overlap
Motif DE_72h DE_72h-NR5A1_MA1540.3 12 bp overlap
NR6A1 2 datasets
Motif DE_60h DE_60h-NR6A1_MA1541.2 14 bp overlap
Motif DE_72h DE_72h-NR6A1_MA1541.2 14 bp overlap
Nkx3-1 2 datasets
Motif DE_60h DE_60h-Nkx3-1_MA0124.3 7 bp overlap
Motif DE_72h DE_72h-Nkx3-1_MA0124.3 7 bp overlap
Nkx3-2 2 datasets
Motif DE_60h DE_60h-Nkx3-2_MA0122.4 10 bp overlap
Motif DE_72h DE_72h-Nkx3-2_MA0122.4 10 bp overlap
Nr1H2 2 datasets
Motif DE_60h DE_60h-Nr1H2_MA1996.2 6 bp overlap
Motif DE_72h DE_72h-Nr1H2_MA1996.2 6 bp overlap
Nr1H4 2 datasets
Motif DE_60h DE_60h-Nr1H4_MA1110.3 6 bp overlap
Motif DE_72h DE_72h-Nr1H4_MA1110.3 6 bp overlap
Nr1h3 2 datasets
Motif DE_60h DE_60h-Nr1h3_MA2337.1 6 bp overlap
Motif DE_72h DE_72h-Nr1h3_MA2337.1 6 bp overlap
Nr2e3 2 datasets
Motif DE_60h DE_60h-Nr2e3_MA0164.2 6 bp overlap
Motif DE_72h DE_72h-Nr2e3_MA0164.2 6 bp overlap
Nr5A2 2 datasets
Motif DE_60h DE_60h-Nr5A2_MA0505.3 9 bp overlap
Motif DE_72h DE_72h-Nr5A2_MA0505.3 9 bp overlap
OTX1 2 datasets
Motif DE_60h DE_60h-OTX1_MA0711.2 6 bp overlap
Motif DE_72h DE_72h-OTX1_MA0711.2 6 bp overlap
PAX3-FOXO1 1 dataset
ChIP RH4 GSE140115.PAX3-FOXO1.RH4 335 bp overlap
PITX1 2 datasets
Motif DE_60h DE_60h-PITX1_MA0682.3 6 bp overlap
Motif DE_72h DE_72h-PITX1_MA0682.3 6 bp overlap
PITX2 2 datasets
Motif DE_60h DE_60h-PITX2_MA1547.2 8 bp overlap
Motif DE_72h DE_72h-PITX2_MA1547.2 8 bp overlap
PITX3 2 datasets
Motif DE_60h DE_60h-PITX3_MA0714.2 6 bp overlap
Motif DE_72h DE_72h-PITX3_MA0714.2 6 bp overlap
PKNOX2 2 datasets
Motif DE_60h DE_60h-PKNOX2_MA0783.1 12 bp overlap
Motif DE_72h DE_72h-PKNOX2_MA0783.1 12 bp overlap
POLR2A 3 datasets
ChIP body of pancreas ENCFF501FEC 637 bp overlap
ChIP body of pancreas ENCFF675RCN 625 bp overlap
ChIP body of pancreas ENCFF675RCN 492 bp overlap
Ppara 2 datasets
Motif DE_60h DE_60h-Ppara_MA2338.1 7 bp overlap
Motif DE_72h DE_72h-Ppara_MA2338.1 7 bp overlap
Ptf1A 2 datasets
Motif DE_60h DE_60h-Ptf1A_MA1620.2 8 bp overlap
Motif DE_72h DE_72h-Ptf1A_MA1620.2 8 bp overlap
RHOXF1 2 datasets
Motif DE_60h DE_60h-RHOXF1_MA0719.2 6 bp overlap
Motif DE_72h DE_72h-RHOXF1_MA0719.2 6 bp overlap
RORA 2 datasets
Motif DE_60h DE_60h-RORA_MA0071.1 10 bp overlap
Motif DE_72h DE_72h-RORA_MA0071.1 10 bp overlap
RXRA::VDR 2 datasets
Motif DE_60h DE_60h-RXRAVDR_MA0074.1 15 bp overlap
Motif DE_72h DE_72h-RXRAVDR_MA0074.1 15 bp overlap
Rarg 2 datasets
Motif DE_60h DE_60h-Rarg_MA0860.1 17 bp overlap
Motif DE_72h DE_72h-Rarg_MA0860.1 17 bp overlap
SETDB1 1 dataset
ChIP WN8532 GSE36579.SETDB1.WN8532 87 bp overlap
SNAI2 3 datasets
Motif DE_60h DE_60h-SNAI2_MA0745.3 8 bp overlap
Motif DE_72h DE_72h-SNAI2_MA0745.3 8 bp overlap
ChIP RD_shSNAI2 GSE137168.SNAI2.RD_shSNAI2 200 bp overlap
SNAI3 2 datasets
Motif DE_60h DE_60h-SNAI3_MA1559.2 9 bp overlap
Motif DE_72h DE_72h-SNAI3_MA1559.2 9 bp overlap
SOX10 2 datasets
Motif DE_60h DE_60h-SOX10_MA0442.3 6 bp overlap
Motif DE_72h DE_72h-SOX10_MA0442.3 6 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 324 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 493 bp overlap
SOX4 2 datasets
Motif DE_60h DE_60h-SOX4_MA0867.3 8 bp overlap
Motif DE_72h DE_72h-SOX4_MA0867.3 8 bp overlap
SRF 2 datasets
Motif DE_60h DE_60h-SRF_MA0083.3 16 bp overlap
Motif DE_72h DE_72h-SRF_MA0083.3 16 bp overlap
Sox11 2 datasets
Motif DE_60h DE_60h-Sox11_MA0869.3 8 bp overlap
Motif DE_72h DE_72h-Sox11_MA0869.3 8 bp overlap
Sox17 2 datasets
Motif DE_60h DE_60h-Sox17_MA0078.3 10 bp overlap
Motif DE_72h DE_72h-Sox17_MA0078.3 10 bp overlap
Sox5 2 datasets
Motif DE_60h DE_60h-Sox5_MA0087.3 8 bp overlap
Motif DE_72h DE_72h-Sox5_MA0087.3 8 bp overlap
Sox6 2 datasets
Motif DE_60h DE_60h-Sox6_MA0515.1 10 bp overlap
Motif DE_72h DE_72h-Sox6_MA0515.1 10 bp overlap
Sox7 2 datasets
Motif DE_60h DE_60h-Sox7_MA2095.1 10 bp overlap
Motif DE_72h DE_72h-Sox7_MA2095.1 10 bp overlap
TBX5 6 datasets
ChIP G296S GSE85628.TBX5.G296S 334 bp overlap
ChIP G296S_2 GSE85628.TBX5.G296S_2 334 bp overlap
ChIP G296S_4 GSE85628.TBX5.G296S_4 264 bp overlap
ChIP cardiomyocyte_5 GSE85628.TBX5.cardiomyocyte_5 328 bp overlap
ChIP cardiomyocyte_7 GSE85628.TBX5.cardiomyocyte_7 600 bp overlap
ChIP hiPSC GSE81585.TBX5.hiPSC 328 bp overlap
TGIF1 2 datasets
Motif DE_60h DE_60h-TGIF1_MA0796.1 12 bp overlap
Motif DE_72h DE_72h-TGIF1_MA0796.1 12 bp overlap
TGIF2 2 datasets
Motif DE_60h DE_60h-TGIF2_MA0797.1 12 bp overlap
Motif DE_72h DE_72h-TGIF2_MA0797.1 12 bp overlap
TGIF2LX 2 datasets
Motif DE_60h DE_60h-TGIF2LX_MA1571.1 12 bp overlap
Motif DE_72h DE_72h-TGIF2LX_MA1571.1 12 bp overlap
TGIF2LY 2 datasets
Motif DE_60h DE_60h-TGIF2LY_MA1572.1 12 bp overlap
Motif DE_72h DE_72h-TGIF2LY_MA1572.1 12 bp overlap
ZBTB6 2 datasets
Motif DE_60h DE_60h-ZBTB6_MA1581.2 9 bp overlap
Motif DE_72h DE_72h-ZBTB6_MA1581.2 9 bp overlap
ZEB1 2 datasets
Motif DE_60h DE_60h-ZEB1_MA0103.4 6 bp overlap
Motif DE_72h DE_72h-ZEB1_MA0103.4 6 bp overlap
ZNF143 2 datasets
ChIP FLP143HA_T4 GSE39263.ZNF143.FLP143HA_T4 259 bp overlap
ChIP HeLa GSE39263.ZNF143.HeLa 196 bp overlap
ZNF211 2 datasets
Motif DE_60h DE_60h-ZNF211_MA1974.2 10 bp overlap
Motif DE_72h DE_72h-ZNF211_MA1974.2 10 bp overlap
ZNF213 2 datasets
Motif DE_60h DE_60h-ZNF213_MA2121.1 12 bp overlap
Motif DE_72h DE_72h-ZNF213_MA2121.1 12 bp overlap
ZNF257 2 datasets
Motif DE_60h DE_60h-ZNF257_MA1710.2 10 bp overlap
Motif DE_72h DE_72h-ZNF257_MA1710.2 10 bp overlap
ZNF263 1 dataset
ChIP K-562 ENCSR000EWN.ZNF263.K-562 245 bp overlap
ZNF324 2 datasets
Motif DE_60h DE_60h-ZNF324_MA1977.2 14 bp overlap
Motif DE_72h DE_72h-ZNF324_MA1977.2 14 bp overlap
ZNF418 2 datasets
Motif DE_60h DE_60h-ZNF418_MA1980.1 15 bp overlap
Motif DE_72h DE_72h-ZNF418_MA1980.1 15 bp overlap
ZNF530 2 datasets
Motif DE_60h DE_60h-ZNF530_MA1981.2 14 bp overlap
Motif DE_72h DE_72h-ZNF530_MA1981.2 14 bp overlap
ZNF708 2 datasets
Motif DE_60h DE_60h-ZNF708_MA1730.2 9 bp overlap
Motif DE_72h DE_72h-ZNF708_MA1730.2 9 bp overlap
ZNF768 2 datasets
Motif DE_60h DE_60h-ZNF768_MA1731.2 9 bp overlap
Motif DE_72h DE_72h-ZNF768_MA1731.2 9 bp overlap
ZNF770 2 datasets
Motif DE_60h DE_60h-ZNF770_MA2099.1 8 bp overlap
Motif DE_72h DE_72h-ZNF770_MA2099.1 8 bp overlap
Zfp809 2 datasets
Motif DE_60h DE_60h-Zfp809_MA2125.1 9 bp overlap
Motif DE_72h DE_72h-Zfp809_MA2125.1 9 bp overlap
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