chr1 : 55,623,415 – 55,624,442
1,027 bp 86 TFs 1 linked gene
This 1.0 kb open chromatin element is linked to PRKAA2 and is bound by 86 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
PRKAA2 1021.3 kb Distal Multiome+HiCAR
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr1:55,618,415 – 55,629,442
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
86 transcription factors
Source
Cell type
AFF4 1 dataset
ChIP HeLa_EGF GSE40632.AFF4.HeLa_EGF 147 bp overlap
AR 7 datasets
ChIP LNCaP_androgen-N_hypoxia-Y GSE114732.AR.LNCaP_androgen-N_hypoxia-Y 163 bp overlap
ChIP prostate GSE56288.AR.prostate 313 bp overlap
ChIP prostate_1730_T GSE130408.AR.prostate_1730_T 298 bp overlap
ChIP prostate_1798_T GSE130408.AR.prostate_1798_T 295 bp overlap
ChIP prostate_1816_T GSE130408.AR.prostate_1816_T 273 bp overlap
ChIP prostate_P1 GSE130408.AR.prostate_P1 196 bp overlap
ChIP prostate_P27 GSE130408.AR.prostate_P27 242 bp overlap
Arid3a 1 dataset
Motif DE_48h DE_48h-Arid3a_MA0151.1 6 bp overlap
BARX2 1 dataset
Motif DE_48h DE_48h-BARX2_MA1471.2 9 bp overlap
BHLHE40 1 dataset
ChIP IMR-90 ENCSR957KYB.BHLHE40.IMR-90 141 bp overlap
BRD3 1 dataset
ChIP H-1_DE GSE126661.BRD3.H-1_DE 116 bp overlap
BRD4 5 datasets
ChIP HCC1395 GSE63581.BRD4.HCC1395 234 bp overlap
ChIP HEK293_sgNT GSE129407.BRD4.HEK293_sgNT 290 bp overlap
ChIP IMR-90_QUIES GSE74238.BRD4.IMR-90_QUIES 239 bp overlap
ChIP SUM159PT_100nMtrametinib_24h GSE87418.BRD4.SUM159PT_100nMtrametinib_24h 301 bp overlap
ChIP SUM159PT_DMSO_24h GSE87418.BRD4.SUM159PT_DMSO_24h 170 bp overlap
CREBBP 1 dataset
ChIP fibroblast_proliferating GSE106146.CREBBP.fibroblast_proliferating 253 bp overlap
CTCF 1 dataset
Motif DE_48h DE_48h-CTCF_MA1929.2 31 bp overlap
Crx 3 datasets
Motif DE_48h DE_48h-Crx_MA0467.3 6 bp overlap
Motif DE_60h DE_60h-Crx_MA0467.3 6 bp overlap
Motif DE_72h DE_72h-Crx_MA0467.3 6 bp overlap
Dmbx1 1 dataset
Motif DE_48h DE_48h-Dmbx1_MA0883.2 10 bp overlap
EED 1 dataset
ChIP ProEs GSE59087.EED.ProEs 179 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 449 bp overlap
EP300 1 dataset
ChIP fibroblast_proliferating GSE106146.EP300.fibroblast_proliferating 289 bp overlap
FOS 2 datasets
ChIP IMR-90 ENCSR124AIG.FOS.IMR-90 162 bp overlap
ChIP myometrium_PT886 GSE128230.FOS.myometrium_PT886 107 bp overlap
FOXA1 2 datasets
ChIP pancreatic-progenitor_PP1 GSE104840.FOXA1.pancreatic-progenitor_PP1 214 bp overlap
ChIP prostate_P1 GSE130408.FOXA1.prostate_P1 152 bp overlap
FOXA2 4 datasets
ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.FOXA2.BJ1-hTERT_FOXA2_GATA4_Coexp 254 bp overlap
ChIP DE DE-FOXA2-1 877 bp overlap
ChIP DE DE-FOXA2-2 741 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.FOXA2.pancreatic-progenitor_PP1 307 bp overlap
FOXE1 1 dataset
Motif DE_48h DE_48h-FOXE1_MA1487.3 12 bp overlap
FOXP2 1 dataset
Motif DE_48h DE_48h-FOXP2_MA0593.2 9 bp overlap
Foxq1 1 dataset
Motif DE_48h DE_48h-Foxq1_MA0040.2 10 bp overlap
GATA4 5 datasets
ChIP DE DE-GATA4-1 874 bp overlap
ChIP DE DE-GATA4-2 979 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 313 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 136 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 564 bp overlap
GATA6 14 datasets
ChIP AGS GSE51705.GATA6.AGS 398 bp overlap
ChIP Caco-2_PROLIF GSE23436.GATA6.Caco-2_PROLIF 181 bp overlap
ChIP DE DE-GATA6-1 1027 bp overlap
ChIP DE DE-GATA6-2 975 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 1006 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 1010 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 786 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 981 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 1027 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 1027 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 942 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 705 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 259 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 495 bp overlap
GSC 3 datasets
Motif DE_48h DE_48h-GSC_MA0648.2 6 bp overlap
Motif DE_60h DE_60h-GSC_MA0648.2 6 bp overlap
Motif DE_72h DE_72h-GSC_MA0648.2 6 bp overlap
GSC2 3 datasets
Motif DE_48h DE_48h-GSC2_MA0891.2 6 bp overlap
Motif DE_60h DE_60h-GSC2_MA0891.2 6 bp overlap
Motif DE_72h DE_72h-GSC2_MA0891.2 6 bp overlap
HDAC3 1 dataset
ChIP RH4_DMSO-6H GSE116344.HDAC3.RH4_DMSO-6H 236 bp overlap
HNF1A 1 dataset
Motif DE_48h DE_48h-HNF1A_MA0046.3 13 bp overlap
HOXB13 1 dataset
Motif DE_48h DE_48h-HOXB13_MA0901.3 9 bp overlap
INTS11 1 dataset
ChIP HeLa GSE125534.INTS11.HeLa 155 bp overlap
JUN 1 dataset
ChIP primary-lung-fibroblast_OE GSE114844.JUN.primary-lung-fibroblast_OE 192 bp overlap
Lef1 1 dataset
Motif DE_48h DE_48h-Lef1_MA0768.3 8 bp overlap
MAFK 1 dataset
ChIP IMR-90 ENCFF336DHZ 181 bp overlap
MED1 1 dataset
ChIP hMSC-TERT4_adipocyte-D7 GSE113253.MED1.hMSC-TERT4_adipocyte-D7 72 bp overlap
MED12 3 datasets
ChIP myometrium_PT886 GSE128230.MED12.myometrium_PT886 118 bp overlap
ChIP myometrium_PT916 GSE128230.MED12.myometrium_PT916 57 bp overlap
ChIP myometrium_PT916 GSE128230.MED12.myometrium_PT916 57 bp overlap
MEF2A 2 datasets
Motif DE_48h DE_48h-MEF2A_MA0052.5 10 bp overlap
Motif DE_48h DE_48h-MEF2A_MA0052.5 10 bp overlap
MEF2B 1 dataset
Motif DE_48h DE_48h-MEF2B_MA0660.1 12 bp overlap
MEF2C 1 dataset
Motif DE_48h DE_48h-MEF2C_MA0497.2 11 bp overlap
MEF2D 2 datasets
Motif DE_48h DE_48h-MEF2D_MA0773.1 12 bp overlap
Motif DE_48h DE_48h-MEF2D_MA0773.1 12 bp overlap
MEIS1 1 dataset
Motif DE_48h DE_48h-MEIS1_MA0498.3 5 bp overlap
MGA 1 dataset
ChIP A-549_MGA-OE GSE112188.MGA.A-549_MGA-OE 274 bp overlap
MZF1 1 dataset
Motif DE_48h DE_48h-MZF1_MA0056.3 8 bp overlap
NELFE 2 datasets
ChIP HeLa GSE125534.NELFE.HeLa 280 bp overlap
ChIP HeLa_DOX GSE125534.NELFE.HeLa_DOX 247 bp overlap
NFE2 3 datasets
ChIP K-562 ENCSR552YGL.NFE2.K-562 241 bp overlap
ChIP K-562 ENCSR000FCC.NFE2.K-562 152 bp overlap
ChIP K562 ENCFF047YKA 310 bp overlap
NFE2L2 2 datasets
ChIP IMR-90 ENCFF059WEE 211 bp overlap
ChIP IMR-90 ENCSR197WGI.NFE2L2.IMR-90 204 bp overlap
NR2F2 3 datasets
ChIP liver ENCFF427MRU 272 bp overlap
ChIP liver ENCSR338MMB.NR2F2.liver 193 bp overlap
ChIP liver ENCSR168SMX.NR2F2.liver 311 bp overlap
Nfat5 1 dataset
Motif DE_48h DE_48h-Nfat5_MA0606.3 8 bp overlap
Nfatc2 1 dataset
Motif DE_48h DE_48h-Nfatc2_MA0152.3 8 bp overlap
ONECUT1 1 dataset
ChIP pancreatic-progenitor_PP1 GSE104840.ONECUT1.pancreatic-progenitor_PP1 508 bp overlap
OTX1 3 datasets
Motif DE_48h DE_48h-OTX1_MA0711.2 6 bp overlap
Motif DE_60h DE_60h-OTX1_MA0711.2 6 bp overlap
Motif DE_72h DE_72h-OTX1_MA0711.2 6 bp overlap
OTX2 1 dataset
Motif DE_48h DE_48h-OTX2_MA0712.3 7 bp overlap
PAX5 1 dataset
ChIP fetal_testis GSE100639.PAX5.fetal_testis 105 bp overlap
PGR 2 datasets
ChIP myometrium_NP1 GSE137550.PGR.myometrium_NP1 315 bp overlap
ChIP myometrium_NP2 GSE137550.PGR.myometrium_NP2 423 bp overlap
PHF19 1 dataset
ChIP DU145_SH4 GSE135623.PHF19.DU145_SH4 223 bp overlap
PITX1 3 datasets
Motif DE_48h DE_48h-PITX1_MA0682.3 6 bp overlap
Motif DE_60h DE_60h-PITX1_MA0682.3 6 bp overlap
Motif DE_72h DE_72h-PITX1_MA0682.3 6 bp overlap
PITX2 3 datasets
Motif DE_48h DE_48h-PITX2_MA1547.2 8 bp overlap
Motif DE_60h DE_60h-PITX2_MA1547.2 8 bp overlap
Motif DE_72h DE_72h-PITX2_MA1547.2 8 bp overlap
PITX3 3 datasets
Motif DE_48h DE_48h-PITX3_MA0714.2 6 bp overlap
Motif DE_60h DE_60h-PITX3_MA0714.2 6 bp overlap
Motif DE_72h DE_72h-PITX3_MA0714.2 6 bp overlap
POLR2A 16 datasets
ChIP body of pancreas ENCFF727UBE 320 bp overlap
ChIP esophagus muscularis mucosa ENCFF432ZCY 360 bp overlap
ChIP esophagus muscularis mucosa ENCFF759BBR 99 bp overlap
ChIP esophagus muscularis mucosa ENCFF791ZXN 279 bp overlap
ChIP gastroesophageal sphincter ENCFF070PCA 98 bp overlap
ChIP prostate gland ENCFF545MVF 263 bp overlap
ChIP prostate gland ENCFF545MVF 479 bp overlap
ChIP sigmoid colon ENCFF725QFT 272 bp overlap
ChIP sigmoid colon ENCFF748YVT 283 bp overlap
ChIP sigmoid colon ENCFF754JQR 182 bp overlap
ChIP stomach ENCFF607ZPU 325 bp overlap
ChIP stomach ENCFF820WZN 88 bp overlap
ChIP transverse colon ENCFF607LKE 102 bp overlap
ChIP transverse colon ENCFF610RWV 146 bp overlap
ChIP upper lobe of left lung ENCFF095BJW 312 bp overlap
ChIP upper lobe of left lung ENCFF199JUI 147 bp overlap
POU4F2 1 dataset
ChIP HNPC_DIF GSE74814.POU4F2.HNPC_DIF 178 bp overlap
RAD21 1 dataset
ChIP IMR-90 ENCSR000EFJ.RAD21.IMR-90 241 bp overlap
RELA 2 datasets
ChIP HeLa-B2_TNFA GSE24518.RELA.HeLa-B2_TNFA 134 bp overlap
ChIP IMR-90_TNF GSE43070.RELA.IMR-90_TNF 241 bp overlap
RFX7 1 dataset
Motif DE_48h DE_48h-RFX7_MA1554.2 8 bp overlap
RHOXF1 3 datasets
Motif DE_48h DE_48h-RHOXF1_MA0719.2 6 bp overlap
Motif DE_60h DE_60h-RHOXF1_MA0719.2 6 bp overlap
Motif DE_72h DE_72h-RHOXF1_MA0719.2 6 bp overlap
Rfx6 1 dataset
Motif DE_48h DE_48h-Rfx6_MA1724.2 9 bp overlap
SETDB1 3 datasets
ChIP HEK293 ENCFF676PLV 256 bp overlap
ChIP HEK293 ENCSR348AGV.SETDB1.HEK293 183 bp overlap
ChIP U2OS ENCSR000EYD.SETDB1.U2OS 183 bp overlap
SMAD1 1 dataset
ChIP BG03 GSE36578.SMAD1.BG03 96 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 1025 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 1027 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 864 bp overlap
SMAD2_3 5 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 848 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 994 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 733 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 963 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 951 bp overlap
SMAD3 2 datasets
ChIP HCC1954 GSE104760.SMAD3.HCC1954 119 bp overlap
ChIP HCC1954_TGFb GSE104760.SMAD3.HCC1954_TGFb 233 bp overlap
SMARCA4 1 dataset
ChIP TTC-1240_delC GSE124903.SMARCA4.TTC-1240_delC 219 bp overlap
SMC3 2 datasets
ChIP HeLa-Kyoto_PDS5-depleted GSE102884.SMC3.HeLa-Kyoto_PDS5-depleted 184 bp overlap
ChIP IMR-90 ENCSR000HPG.SMC3.IMR-90 197 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 510 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 678 bp overlap
SPIB 3 datasets
Motif DE_48h DE_48h-SPIB_MA0081.3 13 bp overlap
Motif DE_60h DE_60h-SPIB_MA0081.3 13 bp overlap
Motif DE_72h DE_72h-SPIB_MA0081.3 13 bp overlap
SUPT5H 1 dataset
ChIP HeLa GSE125534.SUPT5H.HeLa 125 bp overlap
Sox6 1 dataset
Motif DE_48h DE_48h-Sox6_MA0515.1 10 bp overlap
Spi1 3 datasets
Motif DE_48h DE_48h-Spi1_MA0080.7 13 bp overlap
Motif DE_60h DE_60h-Spi1_MA0080.7 13 bp overlap
Motif DE_72h DE_72h-Spi1_MA0080.7 13 bp overlap
Stat6 1 dataset
Motif DE_48h DE_48h-Stat6_MA0520.2 10 bp overlap
T 1 dataset
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 238 bp overlap
TCF21 1 dataset
ChIP HCASMC GSE124011.TCF21.HCASMC 391 bp overlap
TFAP2C 1 dataset
ChIP HCC1954 GSE126897.TFAP2C.HCC1954 153 bp overlap
TP53 1 dataset
ChIP IMR-90 GSE42728.TP53.IMR-90 115 bp overlap
ZKSCAN3 1 dataset
Motif DE_48h DE_48h-ZKSCAN3_MA1973.2 14 bp overlap
ZNF214 1 dataset
Motif DE_48h DE_48h-ZNF214_MA1975.2 13 bp overlap
ZNF528 1 dataset
ChIP HEK293 GSE76494.ZNF528.HEK293 182 bp overlap
ZNF573 1 dataset
ChIP HEK293T GSE78099.ZNF573.HEK293T 185 bp overlap
ZNF680 3 datasets
Motif DE_48h DE_48h-ZNF680_MA1729.2 11 bp overlap
Motif DE_60h DE_60h-ZNF680_MA1729.2 11 bp overlap
Motif DE_72h DE_72h-ZNF680_MA1729.2 11 bp overlap
ZNF707 3 datasets
Motif DE_48h DE_48h-ZNF707_MA1715.1 15 bp overlap
Motif DE_60h DE_60h-ZNF707_MA1715.1 15 bp overlap
Motif DE_72h DE_72h-ZNF707_MA1715.1 15 bp overlap
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