chr3 : 3,806,826 – 3,807,302

476 bp 75 TFs 1 linked gene

This 476 bp open chromatin element is linked to LRRN1 and is bound by 75 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
LRRN1		7.4 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

75 transcription factors

ATF2 1 dataset

ChIP WA01 ENCSR000BQU.ATF2.WA01 365 bp overlap

Ahr::Arnt 1 dataset

Motif DE_60h DE_60h-AhrArnt_MA0006.2 5 bp overlap

BACH1 2 datasets

ChIP H1 ENCFF282VDB 321 bp overlap

ChIP WA01 ENCSR000EBQ.BACH1.WA01 301 bp overlap

BARX2 1 dataset

Motif DE_60h DE_60h-BARX2_MA1471.2 9 bp overlap

BRD4 2 datasets

ChIP CHL-1_BAY123897 GSE95585.BRD4.CHL-1_BAY123897 124 bp overlap

ChIP hESC GSE33281.BRD4.hESC 61 bp overlap

CTCFL 1 dataset

Motif DE_60h DE_60h-CTCFL_MA1102.3 8 bp overlap

Crx 1 dataset

Motif DE_60h DE_60h-Crx_MA0467.3 6 bp overlap

DMRTA1 1 dataset

Motif DE_60h DE_60h-DMRTA1_MA1707.2 10 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 174 bp overlap

EP300 1 dataset

ChIP WA01 ENCSR000BKK.EP300.WA01 174 bp overlap

ESR2 1 dataset

Motif DE_60h DE_60h-ESR2_MA0258.2 15 bp overlap

ESRRA 1 dataset

Motif DE_60h DE_60h-ESRRA_MA0592.4 9 bp overlap

EZH2 1 dataset

ChIP A-1847_CARM1-KO GSE95643.EZH2.A-1847_CARM1-KO 476 bp overlap

Esrrg 1 dataset

Motif DE_60h DE_60h-Esrrg_MA0643.2 9 bp overlap

GATA2 1 dataset

Motif DE_60h DE_60h-GATA2_MA0036.4 7 bp overlap

GATA4 3 datasets

ChIP DE DE-GATA4-1 419 bp overlap

ChIP DE DE-GATA4-2 411 bp overlap

Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap

GATA6 7 datasets

ChIP DE DE-GATA6-1 303 bp overlap

ChIP DE DE-GATA6-2 406 bp overlap

Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 295 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 279 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 308 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 299 bp overlap

GSC 1 dataset

Motif DE_60h DE_60h-GSC_MA0648.2 6 bp overlap

GSC2 1 dataset

Motif DE_60h DE_60h-GSC2_MA0891.2 6 bp overlap

Gata3 1 dataset

Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap

INSM1 1 dataset

Motif DE_60h DE_60h-INSM1_MA0155.1 12 bp overlap

Isl1 1 dataset

Motif DE_60h DE_60h-Isl1_MA1608.2 7 bp overlap

JUN 3 datasets

ChIP DE_D1 S08-DE-d1-JUN-exp1 311 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 325 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 294 bp overlap

JUND 1 dataset

ChIP WA01 ENCSR000BKP.JUND.WA01 121 bp overlap

KLF1 1 dataset

Motif DE_60h DE_60h-KLF1_MA0493.3 8 bp overlap

KLF10 1 dataset

Motif DE_60h DE_60h-KLF10_MA1511.2 9 bp overlap

KLF11 1 dataset

Motif DE_60h DE_60h-KLF11_MA1512.2 10 bp overlap

KLF12 1 dataset

Motif DE_60h DE_60h-KLF12_MA0742.2 9 bp overlap

KLF13 1 dataset

Motif DE_60h DE_60h-KLF13_MA0657.2 17 bp overlap

KLF14 1 dataset

Motif DE_60h DE_60h-KLF14_MA0740.2 9 bp overlap

KLF16 1 dataset

Motif DE_60h DE_60h-KLF16_MA0741.1 11 bp overlap

KLF17 1 dataset

Motif DE_60h DE_60h-KLF17_MA1514.2 14 bp overlap

KLF2 1 dataset

Motif DE_60h DE_60h-KLF2_MA1515.2 8 bp overlap

KLF3 1 dataset

Motif DE_60h DE_60h-KLF3_MA1516.2 10 bp overlap

KLF6 1 dataset

Motif DE_60h DE_60h-KLF6_MA1517.2 9 bp overlap

KLF7 1 dataset

Motif DE_60h DE_60h-KLF7_MA1959.2 8 bp overlap

KLF9 1 dataset

Motif DE_60h DE_60h-KLF9_MA1107.3 11 bp overlap

MAFK 2 datasets

ChIP H1 ENCFF854XWE 285 bp overlap

ChIP WA01 ENCSR000EBS.MAFK.WA01 248 bp overlap

NANOG 1 dataset

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 177 bp overlap

NFE2 2 datasets

ChIP K-562 ENCSR552YGL.NFE2.K-562 303 bp overlap

ChIP K562 ENCFF047YKA 405 bp overlap

NFE2L1 1 dataset

ChIP WTC11 ENCFF644BPU 377 bp overlap

NR2C1 1 dataset

Motif DE_60h DE_60h-NR2C1_MA1535.2 6 bp overlap

NR2C2 1 dataset

Motif DE_60h DE_60h-NR2C2_MA1536.2 6 bp overlap

NR2F2 1 dataset

Motif DE_60h DE_60h-NR2F2_MA1111.2 7 bp overlap

NR4A2 1 dataset

Motif DE_60h DE_60h-NR4A2_MA0160.3 8 bp overlap

Nr1H2 1 dataset

Motif DE_60h DE_60h-Nr1H2_MA1996.2 6 bp overlap

Nr1H4 1 dataset

Motif DE_60h DE_60h-Nr1H4_MA1110.3 6 bp overlap

Nr1h3 1 dataset

Motif DE_60h DE_60h-Nr1h3_MA2337.1 6 bp overlap

OTX1 1 dataset

Motif DE_60h DE_60h-OTX1_MA0711.2 6 bp overlap

PITX1 1 dataset

Motif DE_60h DE_60h-PITX1_MA0682.3 6 bp overlap

PITX2 1 dataset

Motif DE_60h DE_60h-PITX2_MA1547.2 8 bp overlap

PITX3 1 dataset

Motif DE_60h DE_60h-PITX3_MA0714.2 6 bp overlap

POLR2A 3 datasets

ChIP H1 ENCFF770YBQ 64 bp overlap

ChIP H1 ENCFF770YBQ 306 bp overlap

ChIP H1 ENCFF770YBQ 420 bp overlap

Ppara 1 dataset

Motif DE_60h DE_60h-Ppara_MA2338.1 7 bp overlap

RARA 1 dataset

Motif DE_60h DE_60h-RARA_MA0730.1 17 bp overlap

RELA 1 dataset

Motif DE_60h DE_60h-RELA_MA0107.1 10 bp overlap

RHOXF1 1 dataset

Motif DE_60h DE_60h-RHOXF1_MA0719.2 6 bp overlap

Rarb 1 dataset

Motif DE_60h DE_60h-Rarb_MA0858.1 17 bp overlap

SIN3A 1 dataset

ChIP WA01 ENCSR000EBO.SIN3A.WA01 147 bp overlap

SOX8 1 dataset

ChIP RH4 GSE116344.SOX8.RH4 212 bp overlap

SP1 1 dataset

ChIP WA01 ENCSR000BIR.SP1.WA01 134 bp overlap

SP3 1 dataset

Motif DE_60h DE_60h-SP3_MA0746.3 11 bp overlap

SP4 1 dataset

Motif DE_60h DE_60h-SP4_MA0685.2 9 bp overlap

SP8 1 dataset

Motif DE_60h DE_60h-SP8_MA0747.2 11 bp overlap

SP9 1 dataset

Motif DE_60h DE_60h-SP9_MA1564.2 10 bp overlap

SPI1 1 dataset

ChIP OCI-Ly3_SHCTR GSE56857.SPI1.OCI-Ly3_SHCTR 181 bp overlap

TAF7 1 dataset

ChIP WA01 ENCSR000BLU.TAF7.WA01 117 bp overlap

THRA 1 dataset

Motif DE_60h DE_60h-THRA_MA1969.2 18 bp overlap

THRB 1 dataset

Motif DE_60h DE_60h-THRB_MA1576.2 18 bp overlap

TRPS1 1 dataset

Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap

VENTX 1 dataset

Motif DE_60h DE_60h-VENTX_MA0724.1 9 bp overlap

ZNF143 1 dataset

Motif DE_60h DE_60h-ZNF143_MA0088.2 16 bp overlap

ZNF184 1 dataset

Motif DE_60h DE_60h-ZNF184_MA2120.1 13 bp overlap

ZNF282 1 dataset

Motif DE_60h DE_60h-ZNF282_MA1154.2 15 bp overlap

ZNF76 1 dataset

Motif DE_60h DE_60h-ZNF76_MA1716.2 17 bp overlap