chr2 : 223,036,572 – 223,037,422

850 bp 77 TFs 1 linked gene

This 850 bp open chromatin element is linked to ACSL3 and is bound by 77 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
ACSL3		176.0 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

77 transcription factors

ASH2L 1 dataset

ChIP WA01 ENCSR850KIP.ASH2L.WA01 467 bp overlap

ATF2 2 datasets

ChIP H1 ENCFF295GZO 571 bp overlap

ChIP WA01 ENCSR000BQU.ATF2.WA01 375 bp overlap

Atoh1 1 dataset

Motif ES_0h ES_0h-Atoh1_MA0461.3 8 bp overlap

BCL6B 1 dataset

Motif ES_0h ES_0h-BCL6B_MA0731.1 17 bp overlap

BHLHA15 1 dataset

Motif ES_0h ES_0h-BHLHA15_MA0607.2 10 bp overlap

BHLHE22 1 dataset

Motif ES_0h ES_0h-BHLHE22_MA0818.2 10 bp overlap

BHLHE23 1 dataset

Motif ES_0h ES_0h-BHLHE23_MA0817.2 10 bp overlap

BRD4 1 dataset

ChIP hESC GSE33281.BRD4.hESC 62 bp overlap

CDX2 1 dataset

Motif ES_0h ES_0h-CDX2_MA0465.3 8 bp overlap

CHD7 1 dataset

ChIP H1 ENCFF126NLU 597 bp overlap

CREB3L4 1 dataset

Motif ES_0h ES_0h-CREB3L4_MA1474.2 10 bp overlap

CTBP2 1 dataset

ChIP WA01 ENCSR000EUO.CTBP2.WA01 547 bp overlap

Crx 1 dataset

Motif ES_0h ES_0h-Crx_MA0467.3 6 bp overlap

DMRTA1 1 dataset

Motif ES_0h ES_0h-DMRTA1_MA1707.2 10 bp overlap

ETV5::FOXO1 1 dataset

Motif ES_0h ES_0h-ETV5FOXO1_MA1947.2 10 bp overlap

EZH2 2 datasets

ChIP H1 ENCFF232NZA 328 bp overlap

ChIP WA01 ENCSR000ASY.EZH2.WA01 156 bp overlap

Elf5 1 dataset

Motif ES_0h ES_0h-Elf5_MA0136.4 8 bp overlap

GATA6 1 dataset

ChIP DE_D2 S55-DE-d2-GATA6-exp2 252 bp overlap

GSC 1 dataset

Motif ES_0h ES_0h-GSC_MA0648.2 6 bp overlap

GSC2 1 dataset

Motif ES_0h ES_0h-GSC2_MA0891.2 6 bp overlap

HDAC2 3 datasets

ChIP H1 ENCFF353UJQ 332 bp overlap

ChIP H1 ENCFF939VKA 237 bp overlap

ChIP WA01 ENCSR000BNR.HDAC2.WA01 191 bp overlap

HIC2 1 dataset

Motif ES_0h ES_0h-HIC2_MA0738.2 6 bp overlap

HOXB13 1 dataset

Motif ES_0h ES_0h-HOXB13_MA0901.3 9 bp overlap

HSF1 1 dataset

Motif ES_0h ES_0h-HSF1_MA0486.2 13 bp overlap

Hoxa13 1 dataset

Motif ES_0h ES_0h-Hoxa13_MA0650.4 8 bp overlap

Hoxd13 1 dataset

Motif ES_0h ES_0h-Hoxd13_MA0909.4 7 bp overlap

IRF2 1 dataset

Motif ES_0h ES_0h-IRF2_MA0051.2 16 bp overlap

JUN 2 datasets

ChIP ESC S34-ESC-d0-JUN-exp2 387 bp overlap

ChIP HUES-8 GSE109524.JUN.HUES-8 375 bp overlap

MEIS1 1 dataset

Motif ES_0h ES_0h-MEIS1_MA0498.3 5 bp overlap

NANOG 3 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 591 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 431 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 608 bp overlap

NFKB1 1 dataset

Motif ES_0h ES_0h-NFKB1_MA0105.4 13 bp overlap

NKX2-2 1 dataset

Motif ES_0h ES_0h-NKX2-2_MA1645.2 8 bp overlap

Nfatc2 1 dataset

Motif ES_0h ES_0h-Nfatc2_MA0152.3 8 bp overlap

OLIG1 1 dataset

Motif ES_0h ES_0h-OLIG1_MA0826.1 10 bp overlap

OLIG2 1 dataset

Motif ES_0h ES_0h-OLIG2_MA0678.1 10 bp overlap

OLIG3 1 dataset

Motif ES_0h ES_0h-OLIG3_MA0827.1 10 bp overlap

ONECUT1 2 datasets

ChIP H9 ERP004206.ONECUT1.H9 218 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.ONECUT1.pancreatic-progenitor_PP1 347 bp overlap

OTX1 1 dataset

Motif ES_0h ES_0h-OTX1_MA0711.2 6 bp overlap

OTX2 2 datasets

Motif ES_0h ES_0h-OTX2_MA0712.3 7 bp overlap

ChIP WTC11 ENCFF634NAO 245 bp overlap

PGR 1 dataset

Motif ES_0h ES_0h-PGR_MA2327.1 9 bp overlap

PITX1 1 dataset

Motif ES_0h ES_0h-PITX1_MA0682.3 6 bp overlap

PITX2 1 dataset

Motif ES_0h ES_0h-PITX2_MA1547.2 8 bp overlap

PITX3 1 dataset

Motif ES_0h ES_0h-PITX3_MA0714.2 6 bp overlap

POU1F1 1 dataset

Motif ES_0h ES_0h-POU1F1_MA0784.3 14 bp overlap

POU2F2 1 dataset

Motif ES_0h ES_0h-POU2F2_MA0507.3 13 bp overlap

POU2F3 1 dataset

Motif ES_0h ES_0h-POU2F3_MA0627.3 9 bp overlap

POU3F1 1 dataset

Motif ES_0h ES_0h-POU3F1_MA0786.2 10 bp overlap

POU3F4 1 dataset

Motif ES_0h ES_0h-POU3F4_MA0789.1 9 bp overlap

POU5F1 8 datasets

ChIP BG03 GSE21614.POU5F1.BG03 153 bp overlap

ChIP DE_D1 DED1-OCT4_Batch_II 252 bp overlap

ChIP H1 ENCFF698ZAP 205 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 596 bp overlap

ChIP NCCIT GSE36134.POU5F1.NCCIT 483 bp overlap

ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 590 bp overlap

ChIP WA01 ENCSR000BMU.POU5F1.WA01 209 bp overlap

ChIP hiPSC GSE56567.POU5F1.hiPSC 339 bp overlap

PPARA::RXRA 1 dataset

Motif ES_0h ES_0h-PPARARXRA_MA1148.2 17 bp overlap

PPARG 1 dataset

Motif ES_0h ES_0h-PPARG_MA0066.2 19 bp overlap

Pparg::Rxra 1 dataset

Motif ES_0h ES_0h-PpargRxra_MA0065.3 13 bp overlap

RHOXF1 1 dataset

Motif ES_0h ES_0h-RHOXF1_MA0719.2 6 bp overlap

SMAD2_3 1 dataset

ChIP ESC S33-ESC-d0-SMAD2_3-exp2 335 bp overlap

SMARCA4 2 datasets

ChIP hiPSC GSE124903.SMARCA4.hiPSC 159 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 362 bp overlap

SMARCB1 1 dataset

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 450 bp overlap

SMARCC1 2 datasets

ChIP ESC S25-ESC-d0-BAF155-exp1 410 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 501 bp overlap

SOX10 1 dataset

Motif ES_0h ES_0h-SOX10_MA0442.3 6 bp overlap

SOX2 3 datasets

ChIP H9 GSE46837.SOX2.H9 156 bp overlap

ChIP hESC GSE18292.SOX2.hESC 95 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 319 bp overlap

SP1 1 dataset

ChIP H1 ENCFF263FUH 321 bp overlap

SP4 1 dataset

ChIP WA01 ENCSR000BQV.SP4.WA01 157 bp overlap

TBP 1 dataset

ChIP K-562 GSE55306.TBP.K-562 53 bp overlap

TCF21 1 dataset

Motif ES_0h ES_0h-TCF21_MA1568.2 10 bp overlap

TCF3 1 dataset

ChIP NPC GSE154479.TCF3.NPC 264 bp overlap

TCF7L1 1 dataset

Motif ES_0h ES_0h-TCF7L1_MA1421.1 12 bp overlap

TEAD1 2 datasets

ChIP WTC11 ENCFF502QUV 405 bp overlap

ChIP WTC11 ENCFF502QUV 379 bp overlap

TRIM28 1 dataset

ChIP hESC GSE115387.TRIM28.hESC 212 bp overlap

USF1 3 datasets

ChIP H1 ENCFF090WVU 241 bp overlap

ChIP WA01 ENCSR000BIU.USF1.WA01 126 bp overlap

ChIP WTC11 ENCFF699QGS 399 bp overlap

USF2 1 dataset

ChIP WTC11 ENCFF139JAW 376 bp overlap

YY1 1 dataset

ChIP WA01 ENCSR000BKD.YY1.WA01 141 bp overlap

ZNF114 1 dataset

ChIP GM23338 ENCSR555KFE.ZNF114.GM23338 203 bp overlap

ZNF207 1 dataset

ChIP WA09 GSE118632.ZNF207.WA09 459 bp overlap

ZNF257 1 dataset

Motif ES_0h ES_0h-ZNF257_MA1710.2 10 bp overlap

ZNF324 1 dataset

Motif ES_0h ES_0h-ZNF324_MA1977.2 14 bp overlap

ZNF331 1 dataset

Motif ES_0h ES_0h-ZNF331_MA1726.2 10 bp overlap

ZNF423 2 datasets

ChIP WTC11 ENCFF574PBR 133 bp overlap

ChIP WTC11 ENCFF574PBR 317 bp overlap

ZNF462 2 datasets

ChIP GM23338 ENCFF896CCA 251 bp overlap

ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 484 bp overlap