chr1 : 47,431,307 – 47,431,881

574 bp 90 TFs 2 linked genes

This 574 bp open chromatin element is linked to FOXD2-AS1 and FOXD2 and is bound by 90 transcription factors.

Linked Genes

2 genes

Gene	Expression	Dist. to TSS	Distance	Link type
FOXD2-AS1		2.8 kb	Proximal	Proximity
FOXD2		6.2 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

90 transcription factors

APC 1 dataset

ChIP HCT-116 GSE103894.APC.HCT-116 284 bp overlap

ARID1A 1 dataset

ChIP RMG-I GSE104545.ARID1A.RMG-I 300 bp overlap

ATF2 1 dataset

ChIP WA01 ENCSR000BQU.ATF2.WA01 175 bp overlap

ATF3 1 dataset

ChIP HCT-116_DMSO GSE74355.ATF3.HCT-116_DMSO 99 bp overlap

ATF4 3 datasets

Motif DE_24h DE_24h-ATF4_MA0833.3 10 bp overlap

ChIP K-562 ENCSR145TSJ.ATF4.K-562 331 bp overlap

ChIP K562 ENCFF674KTF 194 bp overlap

BCL6B 1 dataset

Motif DE_24h DE_24h-BCL6B_MA0731.1 17 bp overlap

BRD2 2 datasets

ChIP THP-1_DMSO GSE138084.BRD2.THP-1_DMSO 199 bp overlap

ChIP THP-1_iBET-BD1 GSE138084.BRD2.THP-1_iBET-BD1 175 bp overlap

CEBPG 1 dataset

ChIP K562 ENCFF651CMK 317 bp overlap

CREB1 2 datasets

Motif DE_24h DE_24h-CREB1_MA0018.5 8 bp overlap

ChIP GM12878 ENCFF870CVH 253 bp overlap

CTCF 3 datasets

ChIP GM12873 ENCFF711LOS 201 bp overlap

ChIP choroid plexus epithelial cell ENCFF407YNR 177 bp overlap

ChIP endothelial_brain-microvascular ENCSR000DTA.CTCF.endothelial_brain-microvascular 126 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF274GAT 264 bp overlap

EBF1 1 dataset

ChIP MUTUL GSE75503.EBF1.MUTUL 223 bp overlap

EBF3 2 datasets

Motif DE_12h DE_12h-EBF3_MA1637.2 9 bp overlap

Motif DE_24h DE_24h-EBF3_MA1637.2 9 bp overlap

ERF::FOXO1 1 dataset

Motif DE_24h DE_24h-ERFFOXO1_MA1936.2 12 bp overlap

ETV5::FOXI1 1 dataset

Motif DE_24h DE_24h-ETV5FOXI1_MA1946.2 12 bp overlap

ETV5::FOXO1 1 dataset

Motif DE_24h DE_24h-ETV5FOXO1_MA1947.2 10 bp overlap

EZH2 2 datasets

ChIP GM23338 ENCSR045YHA.EZH2.GM23338 355 bp overlap

ChIP WA01 ENCSR000ASY.EZH2.WA01 340 bp overlap

Ebf2 2 datasets

Motif DE_12h DE_12h-Ebf2_MA1604.2 9 bp overlap

Motif DE_24h DE_24h-Ebf2_MA1604.2 9 bp overlap

FLI1::FOXI1 1 dataset

Motif DE_24h DE_24h-FLI1FOXI1_MA1950.2 11 bp overlap

FOSL1 1 dataset

ChIP BT-549 GSE112961.FOSL1.BT-549 144 bp overlap

FOXO1::ELF1 1 dataset

Motif DE_24h DE_24h-FOXO1ELF1_MA1953.2 13 bp overlap

FOXO1::ELK1 1 dataset

Motif DE_24h DE_24h-FOXO1ELK1_MA1954.2 13 bp overlap

FOXO1::ELK3 1 dataset

Motif DE_24h DE_24h-FOXO1ELK3_MA1955.2 13 bp overlap

FOXO1::FLI1 1 dataset

Motif DE_24h DE_24h-FOXO1FLI1_MA1956.2 13 bp overlap

Gli2 1 dataset

Motif DE_24h DE_24h-Gli2_MA0734.4 9 bp overlap

Hand1 2 datasets

Motif DE_12h DE_12h-Hand1_MA2123.1 9 bp overlap

Motif DE_24h DE_24h-Hand1_MA2123.1 9 bp overlap

IKZF3 2 datasets

ChIP HEK293 ENCFF518OXG 371 bp overlap

ChIP HEK293 ENCSR304AMN.IKZF3.HEK293 185 bp overlap

INSM1 3 datasets

Motif DE_12h DE_12h-INSM1_MA0155.1 12 bp overlap

Motif DE_24h DE_24h-INSM1_MA0155.1 12 bp overlap

JARID2 1 dataset

ChIP UTEIPS6 GSE48516.JARID2.UTEIPS6 99 bp overlap

KLF16 2 datasets

Motif DE_12h DE_12h-KLF16_MA0741.1 11 bp overlap

Motif DE_24h DE_24h-KLF16_MA0741.1 11 bp overlap

KLF17 2 datasets

Motif DE_12h DE_12h-KLF17_MA1514.2 14 bp overlap

Motif DE_24h DE_24h-KLF17_MA1514.2 14 bp overlap

KMT2A 1 dataset

ChIP MV4-11 GSE79899.KMT2A.MV4-11 219 bp overlap

MAZ 3 datasets

ChIP HEK293 ENCFF994GSG 461 bp overlap

ChIP HEK293 GSE76494.MAZ.HEK293 227 bp overlap

ChIP HEK293 ENCSR290SSQ.MAZ.HEK293 263 bp overlap

MGA::EVX1 2 datasets

Motif DE_12h DE_12h-MGAEVX1_MA1960.2 11 bp overlap

Motif DE_24h DE_24h-MGAEVX1_MA1960.2 11 bp overlap

NFATC3 2 datasets

Motif DE_12h DE_12h-NFATC3_MA0625.3 6 bp overlap

Motif DE_24h DE_24h-NFATC3_MA0625.3 6 bp overlap

Nfat5 2 datasets

Motif DE_12h DE_12h-Nfat5_MA0606.3 8 bp overlap

Motif DE_24h DE_24h-Nfat5_MA0606.3 8 bp overlap

Nfatc1 2 datasets

Motif DE_12h DE_12h-Nfatc1_MA0624.3 6 bp overlap

Motif DE_24h DE_24h-Nfatc1_MA0624.3 6 bp overlap

PARP1 1 dataset

ChIP MCF-10A GSE93038.PARP1.MCF-10A 509 bp overlap

PATZ1 2 datasets

ChIP HEK293 ENCFF016MNJ 445 bp overlap

ChIP HEK293 ENCSR966ULI.PATZ1.HEK293 258 bp overlap

PHIP 1 dataset

ChIP HEK293_ab833 GSE101646.PHIP.HEK293_ab833 180 bp overlap

PLAG1 1 dataset

Motif DE_24h DE_24h-PLAG1_MA0163.1 14 bp overlap

POU2F3 1 dataset

ChIP NCI-H1048 GSE115123.POU2F3.NCI-H1048 206 bp overlap

PRDM10 1 dataset

ChIP HEK293 ENCFF145WQQ 234 bp overlap

PRDM9 2 datasets

Motif DE_12h DE_12h-PRDM9_MA1723.2 20 bp overlap

Motif DE_24h DE_24h-PRDM9_MA1723.2 20 bp overlap

RAD21 1 dataset

ChIP HEK293_siYAP GSE130135.RAD21.HEK293_siYAP 69 bp overlap

RBPJ 2 datasets

Motif DE_12h DE_12h-RBPJ_MA1116.2 6 bp overlap

Motif DE_24h DE_24h-RBPJ_MA1116.2 6 bp overlap

RELA 1 dataset

ChIP SGBS_TNF GSE64233.RELA.SGBS_TNF 192 bp overlap

RNF2 1 dataset

ChIP WA09_heat-shock GSE105028.RNF2.WA09_heat-shock 211 bp overlap

RREB1 2 datasets

Motif DE_12h DE_12h-RREB1_MA0073.2 19 bp overlap

Motif DE_24h DE_24h-RREB1_MA0073.2 19 bp overlap

RUNX1 1 dataset

ChIP SKH1_RUNX1-EVI1_KD GSE87283.RUNX1.SKH1_RUNX1-EVI1_KD 163 bp overlap

RYBP 1 dataset

ChIP WA01 GSE104690.RYBP.WA01 121 bp overlap

SCRT1 1 dataset

Motif DE_24h DE_24h-SCRT1_MA0743.3 10 bp overlap

SCRT2 2 datasets

Motif DE_24h DE_24h-SCRT2_MA0744.3 10 bp overlap

ChIP HEK293 ENCFF711QQB 521 bp overlap

SMAD2 2 datasets

Motif DE_12h DE_12h-SMAD2_MA1964.2 6 bp overlap

Motif DE_24h DE_24h-SMAD2_MA1964.2 6 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 279 bp overlap

SMARCA4 1 dataset

ChIP Aska-SS_shSSX GSE108025.SMARCA4.Aska-SS_shSSX 165 bp overlap

SMARCC1 1 dataset

ChIP SYO-1_shCt GSE139053.SMARCC1.SYO-1_shCt 90 bp overlap

SP2 1 dataset

ChIP HEK293 GSE76494.SP2.HEK293 220 bp overlap

SP4 1 dataset

ChIP HEK293 GSE76494.SP4.HEK293 268 bp overlap

SP5 2 datasets

Motif DE_12h DE_12h-SP5_MA1965.2 6 bp overlap

Motif DE_24h DE_24h-SP5_MA1965.2 6 bp overlap

SS18 2 datasets

ChIP SYO-1 GSE108025.SS18.SYO-1 574 bp overlap

ChIP SYO-1_shCt GSE139053.SS18.SYO-1_shCt 324 bp overlap

SUPT5H 1 dataset

ChIP HCT-116_DMSO GSE138548.SUPT5H.HCT-116_DMSO 193 bp overlap

SUZ12 1 dataset

ChIP hiPSC_WT GSE124903.SUZ12.hiPSC_WT 574 bp overlap

Stat5a 1 dataset

Motif DE_24h DE_24h-Stat5a_MA1624.2 9 bp overlap

Stat5a::Stat5b 1 dataset

Motif DE_24h DE_24h-Stat5aStat5b_MA0519.2 9 bp overlap

TEAD1 1 dataset

Motif DE_24h DE_24h-TEAD1_MA0090.4 9 bp overlap

TERF1 1 dataset

ChIP LCL GSE55053.TERF1.LCL 135 bp overlap

TFAP2C 1 dataset

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 301 bp overlap

Wt1 2 datasets

Motif DE_12h DE_12h-Wt1_MA1627.2 10 bp overlap

Motif DE_24h DE_24h-Wt1_MA1627.2 10 bp overlap

ZEB1 1 dataset

ChIP GM12878 ENCSR000BND.ZEB1.GM12878 166 bp overlap

ZEB2 1 dataset

ChIP HEK293 ENCSR417VWF.ZEB2.HEK293 381 bp overlap

ZIC1 1 dataset

Motif DE_24h DE_24h-ZIC1_MA0696.1 14 bp overlap

ZIC4 1 dataset

Motif DE_24h DE_24h-ZIC4_MA0751.2 14 bp overlap

ZIC5 1 dataset

Motif DE_24h DE_24h-ZIC5_MA1584.2 15 bp overlap

ZNF143 1 dataset

ChIP HeLa GSE39263.ZNF143.HeLa 196 bp overlap

ZNF148 2 datasets

Motif DE_12h DE_12h-ZNF148_MA1653.2 10 bp overlap

Motif DE_24h DE_24h-ZNF148_MA1653.2 10 bp overlap

ZNF189 3 datasets

Motif DE_12h DE_12h-ZNF189_MA1725.2 9 bp overlap

Motif DE_24h DE_24h-ZNF189_MA1725.2 9 bp overlap

ChIP HEK293 ENCFF638TIB 457 bp overlap

ZNF281 2 datasets

Motif DE_12h DE_12h-ZNF281_MA1630.3 10 bp overlap

Motif DE_24h DE_24h-ZNF281_MA1630.3 10 bp overlap

ZNF317 1 dataset

Motif DE_24h DE_24h-ZNF317_MA1593.2 8 bp overlap

ZNF331 1 dataset

Motif DE_24h DE_24h-ZNF331_MA1726.2 10 bp overlap

ZNF354C 2 datasets

Motif DE_12h DE_12h-ZNF354C_MA0130.1 6 bp overlap

Motif DE_24h DE_24h-ZNF354C_MA0130.1 6 bp overlap

ZNF395 2 datasets

ChIP K562 ENCFF464EIT 574 bp overlap

ChIP K562 ENCFF464EIT 193 bp overlap

ZNF460 1 dataset

Motif DE_24h DE_24h-ZNF460_MA1596.1 16 bp overlap

ZNF467 1 dataset

ChIP HEK293 GSE76494.ZNF467.HEK293 224 bp overlap

ZNF626 1 dataset

ChIP HEK293T GSE78099.ZNF626.HEK293T 268 bp overlap

ZNF692 1 dataset

ChIP HEK293 ENCSR418MKG.ZNF692.HEK293 405 bp overlap

ZNF695 1 dataset

ChIP HEK293T GSE78099.ZNF695.HEK293T 130 bp overlap

ZNF766 3 datasets

Motif DE_12h DE_12h-ZNF766_MA2098.1 9 bp overlap

Motif DE_24h DE_24h-ZNF766_MA2098.1 9 bp overlap

ChIP K562 ENCFF348LDO 475 bp overlap

ZNF770 1 dataset

ChIP HEK293 GSE76494.ZNF770.HEK293 96 bp overlap

Zfp809 2 datasets

Motif DE_12h DE_12h-Zfp809_MA2125.1 9 bp overlap

Motif DE_24h DE_24h-Zfp809_MA2125.1 9 bp overlap