chr1:35,533,667–35,534,085

chr1 : 35,533,667 – 35,534,085

418 bp 64 TFs 6 linked genes

This 418 bp open chromatin element is linked to 6 target genes and is bound by 64 transcription factors.

Linked Genes

6 genes

Gene	Expression	Dist. to TSS	Distance	Link type
KIAA0319L		23.7 kb	Distal	Multiome
PSMB2		107.6 kb	Distal	Multiome
CLSPN		236.1 kb	Distal	Multiome
ZMYM4		265.2 kb	Distal	Multiome
AGO4		274.1 kb	Distal	Multiome
SFPQ		340.8 kb	Distal	Multiome+HiCAR

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

64 transcription factors

ARID1B 2 datasets

ChIP K-562 ENCSR822CCM.ARID1B.K-562 274 bp overlap

ChIP K562 ENCFF938UXQ 214 bp overlap

ASXL3 1 dataset

ChIP NCI-H1963_Ab2 GSE145028.ASXL3.NCI-H1963_Ab2 79 bp overlap

BAP1 2 datasets

ChIP NCI-H1963_shASXL3 GSE145028.BAP1.NCI-H1963_shASXL3 418 bp overlap

ChIP NCI-H1963_shNONT GSE145028.BAP1.NCI-H1963_shNONT 418 bp overlap

BCL11A 3 datasets

ChIP CD34_Day5_30min GSE104676.BCL11A.CD34_Day5_30min 218 bp overlap

ChIP CD34_Day9_90min GSE104676.BCL11A.CD34_Day9_90min 78 bp overlap

ChIP HUDEP-2_90min GSE104676.BCL11A.HUDEP-2_90min 96 bp overlap

ChIP K-562 ENCSR808AKZ.BCOR.K-562 240 bp overlap

ChIP K-562_DMSO GSE138084.BRD3.K-562_DMSO 195 bp overlap

BRD4 5 datasets

ChIP K-562_iBET-IFNG GSE138084.BRD4.K-562_iBET-IFNG 243 bp overlap

ChIP NCI-H1963 GSE145028.BRD4.NCI-H1963 418 bp overlap

ChIP NCI-H1963_dBET6 GSE145028.BRD4.NCI-H1963_dBET6 352 bp overlap

ChIP NCI-H1963_shASXL3 GSE145028.BRD4.NCI-H1963_shASXL3 418 bp overlap

ChIP NCI-H1963_shNONT GSE145028.BRD4.NCI-H1963_shNONT 418 bp overlap

CBFA2T2 2 datasets

ChIP K-562 ENCSR699PVC.CBFA2T2.K-562 259 bp overlap

ChIP K562 ENCFF963TXY 327 bp overlap

CBFA2T3 2 datasets

ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 348 bp overlap

ChIP K562 ENCFF673OEZ 265 bp overlap

CC2D1A 1 dataset

ChIP K-562 ENCSR343IFJ.CC2D1A.K-562 215 bp overlap

CEBPD 1 dataset

ChIP K-562 ENCSR000BVY.CEBPD.K-562 154 bp overlap

CHAMP1 1 dataset

ChIP K562 ENCFF860ZIW 394 bp overlap

CTCF 5 datasets

ChIP K-562_15173 GSE131349.CTCF.K-562_15173 102 bp overlap

ChIP K-562_15776 GSE131349.CTCF.K-562_15776 98 bp overlap

ChIP K-562_8004 GSE131349.CTCF.K-562_8004 101 bp overlap

ChIP erythroblast_adult_erythroblasts GSE102184.CTCF.erythroblast_adult_erythroblasts 214 bp overlap

ChIP erythroid_Don001 GSE137982.CTCF.erythroid_Don001 162 bp overlap

DPF2 2 datasets

ChIP K-562 ENCSR219BXP.DPF2.K-562 287 bp overlap

ChIP K562 ENCFF775HUO 394 bp overlap

ChIP K-562 ENCSR000BLI.E2F6.K-562 100 bp overlap

ChIP K-562 ENCSR731LHZ.E4F1.K-562 296 bp overlap

EHMT2 1 dataset

ChIP K-562 ENCSR175EOM.EHMT2.K-562 239 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 314 bp overlap

ChIP SU-DHL-5 GSE45982.EZH2.SU-DHL-5 64 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 276 bp overlap

ChIP DE DE-FOXA2-2 271 bp overlap

FOXM1 1 dataset

ChIP K-562 ENCSR429QPP.FOXM1.K-562 274 bp overlap

GATA1 13 datasets

ChIP CD34_Day7_30min GSE104676.GATA1.CD34_Day7_30min 190 bp overlap

ChIP CD34_ERYTH_BIO GSE29194.GATA1.CD34_ERYTH_BIO 213 bp overlap

ChIP CD34_ERYTH_BMP GSE29194.GATA1.CD34_ERYTH_BMP 166 bp overlap

ChIP HUDEP-2_30min GSE104676.GATA1.HUDEP-2_30min 156 bp overlap

ChIP K-562 GSE107726.GATA1.K-562 271 bp overlap

ChIP K-562_dCas9-LSD1 GSE132212.GATA1.K-562_dCas9-LSD1 214 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 241 bp overlap

ChIP erythroblast ENCFF867JAR 248 bp overlap

ChIP erythroblast ENCFF867JAR 416 bp overlap

ChIP erythroblast ENCSR000EXP.GATA1.erythroblast 418 bp overlap

ChIP erythroid-progenitor GSE124163.GATA1.erythroid-progenitor 166 bp overlap

ChIP erythroid_Don001 GSE137982.GATA1.erythroid_Don001 220 bp overlap

ChIP erythroid_Don003 GSE137982.GATA1.erythroid_Don003 278 bp overlap

GATA2 4 datasets

ChIP CD34_ACY957 GSE60792.GATA2.CD34_ACY957 141 bp overlap

ChIP K-562 ENCSR000EWG.GATA2.K-562 172 bp overlap

ChIP K-562 ENCSR000BKM.GATA2.K-562 114 bp overlap

ChIP K562 ENCFF544PCK 251 bp overlap

GATA4 3 datasets

ChIP DE DE-GATA4-1 325 bp overlap

ChIP DE DE-GATA4-2 418 bp overlap

ChIP foregut GSE117136.GATA4.foregut 263 bp overlap

GATA6 9 datasets

ChIP DE DE-GATA6-1 374 bp overlap

ChIP DE DE-GATA6-2 418 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 418 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 418 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 418 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 418 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 418 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 418 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 418 bp overlap

HDAC2 1 dataset

ChIP K-562 ENCSR893WSB.HDAC2.K-562 265 bp overlap

HDGF 2 datasets

ChIP K-562 ENCSR197ALX.HDGF.K-562 319 bp overlap

ChIP K-562 ENCSR563YDA.HDGF.K-562 342 bp overlap

ChIP DE_D1 S08-DE-d1-JUN-exp1 332 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 368 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 364 bp overlap

L3MBTL2 3 datasets

ChIP K-562 ENCSR530XQI.L3MBTL2.K-562 353 bp overlap

ChIP K562 ENCFF320EQC 374 bp overlap

ChIP K562 ENCFF320EQC 418 bp overlap

LDB1 2 datasets

ChIP HEP GSE52637.LDB1.HEP 213 bp overlap

ChIP K-562 GSE142227.LDB1.K-562 276 bp overlap

ChIP K562 ENCFF524IJO 114 bp overlap

ChIP K-562 ENCSR710WLO.MGA.K-562 376 bp overlap

ChIP K562 ENCFF140CEX 405 bp overlap

ChIP K562 ENCFF140CEX 191 bp overlap

MIER1 1 dataset

ChIP K-562 ENCSR426MDV.MIER1.K-562 307 bp overlap

MORC2 1 dataset

ChIP K-562 GSE95374.MORC2.K-562 418 bp overlap

MYBL2 1 dataset

ChIP K-562 ENCSR162IEM.MYBL2.K-562 210 bp overlap

NCOR1 5 datasets

ChIP K-562 ENCSR798ILC.NCOR1.K-562 235 bp overlap

ChIP K-562 ENCSR910JAI.NCOR1.K-562 201 bp overlap

ChIP K562 ENCFF788MPU 351 bp overlap

ChIP K562 ENCFF866HRM 300 bp overlap

ChIP K562 ENCFF866HRM 355 bp overlap

ChIP ProEs GSE59087.NFE2.ProEs 208 bp overlap

NFIC 2 datasets

ChIP K-562 ENCSR796ITY.NFIC.K-562 249 bp overlap

ChIP K562 ENCFF167YID 371 bp overlap

ChIP K-562 GSE26439.NFYB.K-562 214 bp overlap

PKNOX1 3 datasets

ChIP K-562 ENCSR115SMW.PKNOX1.K-562 377 bp overlap

ChIP K562 ENCFF236IUS 416 bp overlap

ChIP K562 ENCFF236IUS 256 bp overlap

PRDM10 1 dataset

ChIP K-562 ENCSR120MPG.PRDM10.K-562 312 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 418 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 418 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 418 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 418 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 418 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 418 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 418 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 418 bp overlap

SMAD4 1 dataset

ChIP endoderm GSE29422.SMAD4.endoderm 141 bp overlap

SMARCA4 3 datasets

ChIP K-562 ENCSR643VTW.SMARCA4.K-562 316 bp overlap

ChIP K-562 ENCSR587OQL.SMARCA4.K-562 255 bp overlap

ChIP K562 ENCFF316MCJ 394 bp overlap

SMARCC1 1 dataset

ChIP DE_D1 S15-DE-d1-BAF155-exp1 273 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 300 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 393 bp overlap

ChIP hESC GSE18292.SOX2.hESC 78 bp overlap

ChIP K-562 ENCSR788RSW.SOX6.K-562 255 bp overlap

TAL1 14 datasets

ChIP CD34 GSE52924.TAL1.CD34 218 bp overlap

ChIP HSPC-CD34pos GSE93372.TAL1.HSPC-CD34pos 259 bp overlap

ChIP K-562 GSE107726.TAL1.K-562 233 bp overlap

ChIP K-562 ENCSR106FRG.TAL1.K-562 249 bp overlap

ChIP K-562 ENCSR000EHB.TAL1.K-562 198 bp overlap

ChIP K-562_dCas9-KRAB GSE132212.TAL1.K-562_dCas9-KRAB 218 bp overlap

ChIP K-562_dCas9-LSD1 GSE132212.TAL1.K-562_dCas9-LSD1 234 bp overlap

ChIP K-562_enCRISPRi-KL GSE132212.TAL1.K-562_enCRISPRi-KL 245 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.TAL1.K-562_enCRISPRi-LK 256 bp overlap

ChIP K-562_sgGal4 GSE132212.TAL1.K-562_sgGal4 231 bp overlap

ChIP K562 ENCFF620GMX 326 bp overlap

ChIP K562 ENCFF661CCK 224 bp overlap

ChIP ProEs GSE59087.TAL1.ProEs 241 bp overlap

ChIP erythroid GSE42390.TAL1.erythroid 216 bp overlap

TAL1_SCL 1 dataset

ChIP Jurkat GSE25000.TAL1_SCL.Jurkat 144 bp overlap

TCF12 2 datasets

ChIP K-562 ENCSR744WOO.TCF12.K-562 287 bp overlap

ChIP K562 ENCFF931DJY 141 bp overlap

TCF21 1 dataset

ChIP HCASMC GSE124011.TCF21.HCASMC 57 bp overlap

TCF3 2 datasets

ChIP K-562 ENCSR970OJY.TCF3.K-562 143 bp overlap

ChIP K562 ENCFF319QZT 282 bp overlap

TRIM24 1 dataset

ChIP K-562 ENCSR907MZR.TRIM24.K-562 251 bp overlap

TRIM28 1 dataset

ChIP K-562 ENCSR000BRW.TRIM28.K-562 181 bp overlap

YY1 17 datasets

ChIP ALL GSE145549.YY1.ALL 327 bp overlap

ChIP GM12878 ENCFF908JTL 253 bp overlap

ChIP GM12878 ENCSR000EUM.YY1.GM12878 125 bp overlap

ChIP GM12892 ENCFF802MHJ 222 bp overlap

ChIP GM12892 ENCSR000BLT.YY1.GM12892 211 bp overlap

ChIP H1 ENCFF524BTL 263 bp overlap

ChIP Ishikawa ENCFF505XQX 233 bp overlap

ChIP Ishikawa ENCSR000BSY.YY1.Ishikawa 92 bp overlap

ChIP K-562 ENCSR000BMH.YY1.K-562 364 bp overlap

ChIP K-562 ENCSR000EWF.YY1.K-562 182 bp overlap

ChIP K-562 ENCSR000BKU.YY1.K-562 155 bp overlap

ChIP K562 ENCFF660QRE 201 bp overlap

ChIP K562 ENCFF768DPZ 232 bp overlap

ChIP NT2-D1 ENCSR000EXG.YY1.NT2-D1 115 bp overlap

ChIP SK-N-SH ENCSR000BSM.YY1.SK-N-SH 132 bp overlap

ChIP SK-N-SH ENCSR000BLZ.YY1.SK-N-SH 123 bp overlap

ChIP WA01 ENCSR000BKD.YY1.WA01 258 bp overlap

ZBTB7A 1 dataset

ChIP HUDEP-2 GSE103445.ZBTB7A.HUDEP-2 263 bp overlap

ZFP42 1 dataset

ChIP HEK293 GSE76494.ZFP42.HEK293 110 bp overlap

ZNF24 1 dataset

ChIP K-562 ENCSR695EQB.ZNF24.K-562 273 bp overlap

ZNF440 1 dataset

ChIP HEK293T GSE78099.ZNF440.HEK293T 237 bp overlap

ZNF592 2 datasets

ChIP K-562 ENCSR249BHQ.ZNF592.K-562 227 bp overlap

ChIP K562 ENCFF547OSS 362 bp overlap

ChIP K562 ENCFF096OHS 269 bp overlap