chr2:71,103,036–71,103,639

chr2 : 71,103,036 – 71,103,639

603 bp 56 TFs 6 linked genes

This 603 bp open chromatin element is linked to 6 target genes and is bound by 56 transcription factors.

Linked Genes

6 genes

Gene	Expression	Dist. to TSS	Distance	Link type
MCEE		26.8 kb	Distal	Multiome
MPHOSPH10		26.9 kb	Distal	Multiome
NAGK		35.1 kb	Distal	Multiome
TEX261		108.5 kb	Distal	Multiome
PAIP2B		123.7 kb	Distal	Multiome
ZNF638		173.2 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

56 transcription factors

ARNT2 1 dataset

Motif DE_72h DE_72h-ARNT2_MA1464.2 8 bp overlap

ARNT::HIF1A 1 dataset

Motif DE_72h DE_72h-ARNTHIF1A_MA0259.2 5 bp overlap

ASH2L 1 dataset

ChIP WA01 ENCSR850KIP.ASH2L.WA01 325 bp overlap

ATF2 2 datasets

ChIP H1 ENCFF295GZO 571 bp overlap

ChIP WA01 ENCSR000BQU.ATF2.WA01 216 bp overlap

Motif DE_72h DE_72h-Arnt_MA0004.1 6 bp overlap

Arntl 1 dataset

Motif DE_72h DE_72h-Arntl_MA0603.2 8 bp overlap

BHLHE41 1 dataset

Motif DE_72h DE_72h-BHLHE41_MA0636.1 10 bp overlap

CEBPB 2 datasets

ChIP K-562 ENCSR000EHE.CEBPB.K-562 135 bp overlap

ChIP K562 ENCFF189VBN 237 bp overlap

CREB3L4 1 dataset

Motif DE_72h DE_72h-CREB3L4_MA1474.2 10 bp overlap

CREBBP 1 dataset

ChIP MCF-7 ERP000901.CREBBP.MCF-7 132 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF335XTP 184 bp overlap

Creb3l2 1 dataset

Motif DE_72h DE_72h-Creb3l2_MA0608.1 9 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 129 bp overlap

ChIP SK-N-MC_SHFLI_96H GSE61944.ELF1.SK-N-MC_SHFLI_96H 210 bp overlap

FOXA2 1 dataset

ChIP DE DE-FOXA2-1 350 bp overlap

GATA4 1 dataset

ChIP DE DE-GATA4-2 379 bp overlap

GATA6 8 datasets

ChIP DE DE-GATA6-1 563 bp overlap

ChIP DE DE-GATA6-2 426 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 376 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 456 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 401 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 290 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 445 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 490 bp overlap

GLIS3 1 dataset

ChIP H9_plus GSE109562.GLIS3.H9_plus 180 bp overlap

Motif DE_72h DE_72h-HES1_MA1099.3 8 bp overlap

IKZF1 1 dataset

Motif DE_72h DE_72h-IKZF1_MA1508.2 8 bp overlap

ChIP DE_D1 S08-DE-d1-JUN-exp1 511 bp overlap

ChIP DE_D1 S13-DE-d1-JUN-exp1 264 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 553 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 293 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 445 bp overlap

KDM5B 1 dataset

ChIP HCC2157 GSE46055.KDM5B.HCC2157 212 bp overlap

ChIP keratinocyte GSE140991.KLF3.keratinocyte 433 bp overlap

Motif DE_72h DE_72h-MAX_MA0058.4 6 bp overlap

ChIP H1 ENCFF914VQY 119 bp overlap

ChIP Hep-G2 ENCSR000EDS.MAX.Hep-G2 131 bp overlap

ChIP HepG2 ENCFF102SKR 283 bp overlap

MAX::MYC 1 dataset

Motif DE_72h DE_72h-MAXMYC_MA0059.2 10 bp overlap

MEIS1 1 dataset

Motif DE_72h DE_72h-MEIS1_MA0498.3 5 bp overlap

MITF 7 datasets

ChIP 501-mel GSE137522.MITF.501-mel 346 bp overlap

ChIP 501-mel GSE61965.MITF.501-mel 251 bp overlap

ChIP 501-mel_20ng_K243R GSE137522.MITF.501-mel_20ng_K243R 354 bp overlap

ChIP 501-mel_K243Q GSE137522.MITF.501-mel_K243Q 330 bp overlap

Motif DE_72h DE_72h-MITF_MA0620.4 10 bp overlap

ChIP K-562 ENCSR797SWM.MITF.K-562 322 bp overlap

ChIP K562 ENCFF731XJJ 358 bp overlap

Motif DE_72h DE_72h-MLX_MA0663.1 10 bp overlap

MLXIPL 1 dataset

Motif DE_72h DE_72h-MLXIPL_MA0664.2 8 bp overlap

Motif DE_72h DE_72h-MNT_MA0825.2 6 bp overlap

Motif DE_72h DE_72h-MYC_MA0147.4 8 bp overlap

Mlxip 1 dataset

Motif DE_72h DE_72h-Mlxip_MA0622.2 6 bp overlap

NANOG 8 datasets

ChIP H1 ENCFF747ZPQ 241 bp overlap

ChIP HUES-8 GSE109524.NANOG.HUES-8 332 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 399 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 140 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 561 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 531 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 345 bp overlap

ChIP hESC GSE18292.NANOG.hESC 128 bp overlap

ChIP fetal_testis GSE100639.PAX5.fetal_testis 165 bp overlap

PROX1 1 dataset

ChIP SW480 GSE60390.PROX1.SW480 86 bp overlap

RAD51 4 datasets

ChIP Hep-G2 ENCSR081WLS.RAD51.Hep-G2 267 bp overlap

ChIP HepG2 ENCFF188FEZ 270 bp overlap

ChIP K-562 ENCSR524BUE.RAD51.K-562 339 bp overlap

ChIP K562 ENCFF133ELP 355 bp overlap

SETDB1 1 dataset

ChIP HEK293 ENCFF676PLV 114 bp overlap

SIN3A 1 dataset

ChIP WA01 ENCSR000EBO.SIN3A.WA01 129 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 484 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 533 bp overlap

SMAD2_3 3 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 408 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 439 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 505 bp overlap

SOX2 2 datasets

ChIP LK2_GFP GSE137459.SOX2.LK2_GFP 197 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 223 bp overlap

ChIP H1 ENCFF263FUH 321 bp overlap

ChIP WA01 ENCSR000BIR.SP1.WA01 152 bp overlap

SREBF2 1 dataset

Motif DE_72h DE_72h-SREBF2_MA0828.3 10 bp overlap

STAT3 1 dataset

ChIP HCC70_EtOH GSE85579.STAT3.HCC70_EtOH 219 bp overlap

TEAD1 1 dataset

Motif DE_72h DE_72h-TEAD1_MA0090.4 9 bp overlap

TEAD2 1 dataset

Motif DE_72h DE_72h-TEAD2_MA1121.2 7 bp overlap

TEAD3 1 dataset

Motif DE_72h DE_72h-TEAD3_MA0808.1 8 bp overlap

TEAD4 2 datasets

Motif DE_72h DE_72h-TEAD4_MA0809.3 8 bp overlap

ChIP H1 ENCFF778PAX 145 bp overlap

TFE3 3 datasets

Motif DE_72h DE_72h-TFE3_MA0831.3 10 bp overlap

ChIP Hep-G2 ENCSR589SNT.TFE3.Hep-G2 196 bp overlap

ChIP K562 ENCFF697ABG 317 bp overlap

Motif DE_72h DE_72h-TFEB_MA0692.2 8 bp overlap

Motif DE_72h DE_72h-TFEC_MA0871.3 8 bp overlap

USF1 11 datasets

Motif DE_72h DE_72h-USF1_MA0093.4 10 bp overlap

ChIP H1 ENCFF090WVU 93 bp overlap

ChIP Hep-G2 ENCSR000BGM.USF1.Hep-G2 160 bp overlap

ChIP HepG2 ENCFF201JKA 188 bp overlap

ChIP HepG2 ENCFF807KYJ 201 bp overlap

ChIP Ishikawa ENCFF728IEG 261 bp overlap

ChIP Ishikawa ENCSR000BSX.USF1.Ishikawa 187 bp overlap

ChIP K-562 ENCSR000BKT.USF1.K-562 174 bp overlap

ChIP K562 ENCFF633EZB 265 bp overlap

ChIP WA01 ENCSR000BIU.USF1.WA01 274 bp overlap

ChIP WTC11 ENCFF699QGS 386 bp overlap

USF2 9 datasets

Motif DE_72h DE_72h-USF2_MA0526.5 10 bp overlap

ChIP H1 ENCFF434EDF 273 bp overlap

ChIP Hep-G2 GSE97661.USF2.Hep-G2 329 bp overlap

ChIP Hep-G2 ENCSR000EEF.USF2.Hep-G2 134 bp overlap

ChIP HepG2 ENCFF671JRC 248 bp overlap

ChIP K-562 ENCSR578KEN.USF2.K-562 118 bp overlap

ChIP K562 ENCFF306QPU 403 bp overlap

ChIP WA01 ENCSR000ECD.USF2.WA01 157 bp overlap

ChIP WTC11 ENCFF139JAW 353 bp overlap

ChIP WA01 GSE99202.YAP1.WA01 486 bp overlap

ZNF462 1 dataset

ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 197 bp overlap

ZNF677 1 dataset

Motif DE_72h DE_72h-ZNF677_MA2101.1 12 bp overlap