chr19:20,367,718–20,368,350

chr19 : 20,367,718 – 20,368,350

632 bp 103 TFs 8 linked genes

This 632 bp open chromatin element is linked to 8 target genes and is bound by 103 transcription factors.

Linked Genes

8 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000293570		5.1 kb	Proximal	Proximity
ENSG00000291130		56.9 kb	Distal	Multiome
ENSG00000267383		129.6 kb	Distal	Multiome+HiCAR
ZNF737		197.7 kb	Distal	Multiome
ZNF486		200.9 kb	Distal	Multiome
ZNF90		290.1 kb	Distal	Multiome
ZNF626		293.5 kb	Distal	Multiome
ZNF431		773.9 kb	Distal	Multiome+HiCAR

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

103 transcription factors

ChIP prostate-cancer_PDX_58 GSE130408.AR.prostate-cancer_PDX_58 85 bp overlap

ASCL1 3 datasets

Motif DE_60h DE_60h-ASCL1_MA1631.2 9 bp overlap

Motif DE_72h DE_72h-ASCL1_MA1100.3 8 bp overlap

Motif DE_72h DE_72h-ASCL1_MA1631.2 9 bp overlap

Ascl2 1 dataset

Motif DE_72h DE_72h-Ascl2_MA0816.1 10 bp overlap

BACH1 2 datasets

ChIP H1 ENCFF282VDB 276 bp overlap

ChIP WA01 ENCSR000EBQ.BACH1.WA01 201 bp overlap

BHLHE22 1 dataset

Motif DE_72h DE_72h-BHLHE22_MA1635.2 6 bp overlap

Bach1::Mafk 1 dataset

Motif DE_72h DE_72h-Bach1Mafk_MA0591.2 12 bp overlap

Bhlha15 1 dataset

Motif DE_72h DE_72h-Bhlha15_MA1472.3 8 bp overlap

CTCF 86 datasets

ChIP 22Rv1 ENCFF466OXN 540 bp overlap

ChIP D721Med ENCFF513FYD 211 bp overlap

Motif DE_60h DE_60h-CTCF_MA1930.2 33 bp overlap

Motif DE_72h DE_72h-CTCF_MA1930.2 33 bp overlap

ChIP DND-41 ENCFF913MRA 317 bp overlap

ChIP GM23338 ENCFF531QOI 425 bp overlap

ChIP GM23338 ENCFF772DML 201 bp overlap

ChIP H1 ENCFF414GZI 217 bp overlap

ChIP H1 ENCFF764RHO 277 bp overlap

ChIP H9 ENCFF152GTF 419 bp overlap

ChIP H9 ENCFF152GTF 212 bp overlap

ChIP Loucy ENCFF359TVQ 465 bp overlap

ChIP Loucy ENCSR464DKE.CTCF.Loucy 177 bp overlap

ChIP MM.1S ENCFF869JMQ 421 bp overlap

ChIP MM1-S ENCSR402IDP.CTCF.MM1-S 208 bp overlap

ChIP MM1-S GSE43743.CTCF.MM1-S 150 bp overlap

ChIP OCI-LY1 ENCFF455ESK 144 bp overlap

ChIP OCI-LY7 ENCFF086AXQ 235 bp overlap

ChIP OCI-LY7 ENCFF086AXQ 282 bp overlap

ChIP OCI-Ly1 ENCSR072EUE.CTCF.OCI-Ly1 234 bp overlap

ChIP OCI-Ly7 ENCSR027HML.CTCF.OCI-Ly7 455 bp overlap

ChIP VCaP ENCFF858YQT 374 bp overlap

ChIP WA01_NEUR GSE52457.CTCF.WA01_NEUR 175 bp overlap

ChIP WERI-Rb-1 ENCFF349QKF 231 bp overlap

ChIP WERI-Rb-1 ENCSR000DXW.CTCF.WERI-Rb-1 94 bp overlap

ChIP adrenal gland ENCFF886WNR 501 bp overlap

ChIP body of pancreas ENCFF128ALM 418 bp overlap

ChIP body of pancreas ENCFF269EDN 252 bp overlap

ChIP body of pancreas ENCFF438KTE 246 bp overlap

ChIP body of pancreas ENCFF798MEO 197 bp overlap

ChIP body of pancreas ENCFF881RGF 193 bp overlap

ChIP breast epithelium ENCFF341QWO 411 bp overlap

ChIP cardiac muscle cell ENCFF777TNC 365 bp overlap

ChIP cortical-interneuron_KCl-neg_JQ1-neg GSE117508.CTCF.cortical-interneuron_KCl-neg_JQ1-neg 221 bp overlap

ChIP cortical-interneuron_KCl-neg_JQ1-pos GSE117508.CTCF.cortical-interneuron_KCl-neg_JQ1-pos 173 bp overlap

ChIP cortical-interneuron_KCl-pos_JQ1-neg GSE117508.CTCF.cortical-interneuron_KCl-pos_JQ1-neg 175 bp overlap

ChIP cortical-interneuron_KCl-pos_JQ1-pos GSE117508.CTCF.cortical-interneuron_KCl-pos_JQ1-pos 153 bp overlap

ChIP dorsolateral prefrontal cortex ENCFF245PVD 477 bp overlap

ChIP dorsolateral prefrontal cortex ENCFF245PVD 314 bp overlap

ChIP dorsolateral prefrontal cortex ENCFF277YTN 437 bp overlap

ChIP dorsolateral prefrontal cortex ENCFF631JNO 464 bp overlap

ChIP dorsolateral prefrontal cortex ENCFF733NZH 437 bp overlap

ChIP dorsolateral prefrontal cortex ENCFF835ZSJ 484 bp overlap

ChIP endodermal cell ENCFF471YCZ 197 bp overlap

ChIP epithelial cell of proximal tubule ENCFF763ZKS 331 bp overlap

ChIP esophagus squamous epithelium ENCFF571ODZ 365 bp overlap

ChIP gastroesophageal sphincter ENCFF125ESZ 445 bp overlap

ChIP hESC_NAIVE GSE69646.CTCF.hESC_NAIVE 291 bp overlap

ChIP heart right ventricle ENCFF027ORH 450 bp overlap

ChIP hepatocyte ENCFF263BLJ 345 bp overlap

ChIP hiPSC_IB12 GSE106870.CTCF.hiPSC_IB12 131 bp overlap

ChIP hiPSC_IB7 GSE106870.CTCF.hiPSC_IB7 121 bp overlap

ChIP islet GSE23784.CTCF.islet 211 bp overlap

ChIP islet ERP004003.CTCF.islet 199 bp overlap

ChIP keratinocyte ENCFF667ULX 325 bp overlap

ChIP keratinocyte ENCSR000DWX.CTCF.keratinocyte 196 bp overlap

ChIP kidney ENCFF335EKK 185 bp overlap

ChIP nephron ENCFF589HXU 447 bp overlap

ChIP neural cell ENCFF335ADI 521 bp overlap

ChIP neural progenitor cell ENCFF420RBO 199 bp overlap

ChIP neural progenitor cell ENCFF581WPG 503 bp overlap

ChIP pancreas ENCFF245KEE 345 bp overlap

ChIP pancreas_body ENCSR265PFQ.CTCF.pancreas_body 299 bp overlap

ChIP pancreas_body ENCSR408XTO.CTCF.pancreas_body 174 bp overlap

ChIP pancreas_body ENCSR484DDO.CTCF.pancreas_body 154 bp overlap

ChIP parathyroid adenoma ENCFF173CEN 337 bp overlap

ChIP parathyroid adenoma ENCFF173NJK 221 bp overlap

ChIP progenitor cell of endocrine pancreas ENCFF492KHV 248 bp overlap

ChIP prostate gland ENCFF193LJV 417 bp overlap

ChIP prostate gland ENCFF655GBO 341 bp overlap

ChIP prostate gland ENCFF979KAF 381 bp overlap

ChIP retinal pigment epithelial cell ENCFF810AAG 257 bp overlap

ChIP stomach ENCFF370OWL 417 bp overlap

ChIP stomach ENCFF719DAZ 431 bp overlap

ChIP thyroid gland ENCFF163TUI 174 bp overlap

ChIP thyroid gland ENCFF204HWS 253 bp overlap

ChIP thyroid gland ENCFF300RYK 222 bp overlap

ChIP thyroid gland ENCFF631QRY 325 bp overlap

ChIP thyroid gland ENCFF748ICQ 137 bp overlap

ChIP thyroid gland ENCFF877DRR 414 bp overlap

ChIP thyroid-gland ENCSR033KMZ.CTCF.thyroid-gland 263 bp overlap

ChIP thyroid-gland ENCSR145HBC.CTCF.thyroid-gland 239 bp overlap

ChIP thyroid-gland ENCSR492ZIW.CTCF.thyroid-gland 228 bp overlap

ChIP thyroid-gland ENCSR955BIB.CTCF.thyroid-gland 210 bp overlap

ChIP type B pancreatic cell ENCFF910FNQ 397 bp overlap

ChIP upper lobe of left lung ENCFF277NLT 412 bp overlap

Motif DE_60h DE_60h-Crx_MA0467.3 6 bp overlap

Motif DE_72h DE_72h-Crx_MA0467.3 6 bp overlap

EP300 3 datasets

ChIP H1 ENCFF927IYK 266 bp overlap

ChIP WA01 ENCSR000BKK.EP300.WA01 127 bp overlap

ChIP neural cell ENCFF442QNK 517 bp overlap

FERD3L 1 dataset

Motif DE_72h DE_72h-FERD3L_MA1485.1 14 bp overlap

FIGLA 2 datasets

Motif DE_60h DE_60h-FIGLA_MA0820.2 6 bp overlap

Motif DE_72h DE_72h-FIGLA_MA0820.2 6 bp overlap

FOXA1 1 dataset

ChIP prostate_2030_T GSE130408.FOXA1.prostate_2030_T 173 bp overlap

FOXA2 3 datasets

ChIP DE DE-FOXA2-1 632 bp overlap

ChIP DE DE-FOXA2-2 145 bp overlap

ChIP DE DE-FOXA2-2 374 bp overlap

FOXH1 2 datasets

Motif DE_60h DE_60h-FOXH1_MA0479.2 8 bp overlap

Motif DE_72h DE_72h-FOXH1_MA0479.2 8 bp overlap

FOXK1 1 dataset

ChIP WTC11 ENCFF875IGU 377 bp overlap

FOXP2 1 dataset

Motif DE_72h DE_72h-FOXP2_MA0593.2 9 bp overlap

Foxl2 1 dataset

Motif DE_72h DE_72h-Foxl2_MA1607.2 10 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 272 bp overlap

ChIP DE DE-GATA4-2 342 bp overlap

GATA6 4 datasets

ChIP DE DE-GATA6-1 389 bp overlap

ChIP DE DE-GATA6-2 376 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 327 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 375 bp overlap

Motif DE_60h DE_60h-GSC_MA0648.2 6 bp overlap

Motif DE_72h DE_72h-GSC_MA0648.2 6 bp overlap

GSC2 2 datasets

Motif DE_60h DE_60h-GSC2_MA0891.2 6 bp overlap

Motif DE_72h DE_72h-GSC2_MA0891.2 6 bp overlap

Motif DE_72h DE_72h-Irf1_MA0050.4 11 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 445 bp overlap

Motif DE_72h DE_72h-MAF_MA1520.2 13 bp overlap

MAF::NFE2 1 dataset

Motif DE_72h DE_72h-MAFNFE2_MA0501.2 11 bp overlap

Motif DE_72h DE_72h-MAFA_MA1521.2 13 bp overlap

ChIP islet ERP004003.MAFB.islet 235 bp overlap

MAFG::NFE2L1 2 datasets

Motif DE_72h DE_72h-MAFGNFE2L1_MA0089.3 11 bp overlap

Motif DE_72h DE_72h-MAFGNFE2L1_MA0089.3 11 bp overlap

MAFK 5 datasets

Motif DE_72h DE_72h-MAFK_MA0496.4 10 bp overlap

ChIP H1 ENCFF854XWE 275 bp overlap

ChIP MCF-7 ENCFF558JLG 300 bp overlap

ChIP OCI-Ly7 GSE47784.MAFK.OCI-Ly7 171 bp overlap

ChIP WA01 ENCSR000EBS.MAFK.WA01 222 bp overlap

Motif DE_72h DE_72h-MSC_MA0665.1 10 bp overlap

ChIP neural cell ENCFF623HQN 515 bp overlap

Motif DE_72h DE_72h-MYF5_MA1641.2 8 bp overlap

MYOD1 1 dataset

Motif DE_72h DE_72h-MYOD1_MA0499.3 9 bp overlap

Motif DE_72h DE_72h-MYOG_MA0500.3 8 bp overlap

Motif DE_72h DE_72h-Mafg_MA0659.4 12 bp overlap

NANOG 5 datasets

ChIP H1 ENCFF747ZPQ 241 bp overlap

ChIP HUES-8 GSE109524.NANOG.HUES-8 332 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 182 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 183 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 181 bp overlap

NEUROD1 4 datasets

ChIP D341-Med_shGFP GSE92582.NEUROD1.D341-Med_shGFP 304 bp overlap

ChIP D341-Med_shGFP GSE92582.NEUROD1.D341-Med_shGFP 264 bp overlap

ChIP D341-Med_shNEUROD1-1154 GSE92582.NEUROD1.D341-Med_shNEUROD1-1154 170 bp overlap

ChIP D341-Med_shNEUROD1-1579 GSE92582.NEUROD1.D341-Med_shNEUROD1-1579 180 bp overlap

NHLH1 1 dataset

Motif DE_72h DE_72h-NHLH1_MA0048.3 9 bp overlap

NHLH2 1 dataset

Motif DE_72h DE_72h-NHLH2_MA1529.2 16 bp overlap

Neurod2 1 dataset

Motif DE_72h DE_72h-Neurod2_MA1993.2 6 bp overlap

Nfe2l2 1 dataset

Motif DE_72h DE_72h-Nfe2l2_MA0150.3 11 bp overlap

Nr2e1 1 dataset

Motif DE_72h DE_72h-Nr2e1_MA0676.1 9 bp overlap

OTX1 2 datasets

Motif DE_60h DE_60h-OTX1_MA0711.2 6 bp overlap

Motif DE_72h DE_72h-OTX1_MA0711.2 6 bp overlap

ChIP WTC11 ENCFF634NAO 245 bp overlap

Olig2 1 dataset

Motif DE_72h DE_72h-Olig2_MA1997.2 6 bp overlap

PITX1 2 datasets

Motif DE_60h DE_60h-PITX1_MA0682.3 6 bp overlap

Motif DE_72h DE_72h-PITX1_MA0682.3 6 bp overlap

PITX3 2 datasets

Motif DE_60h DE_60h-PITX3_MA0714.2 6 bp overlap

Motif DE_72h DE_72h-PITX3_MA0714.2 6 bp overlap

POLR2A 4 datasets

ChIP body of pancreas ENCFF501FEC 165 bp overlap

ChIP body of pancreas ENCFF501FEC 412 bp overlap

ChIP body of pancreas ENCFF727UBE 437 bp overlap

ChIP neural cell ENCFF604SPB 103 bp overlap

Prdm15 2 datasets

Motif DE_72h DE_72h-Prdm15_MA1616.2 11 bp overlap

Motif DE_72h DE_72h-Prdm15_MA1616.2 11 bp overlap

Prdm5 1 dataset

Motif DE_72h DE_72h-Prdm5_MA1999.2 11 bp overlap

Ptf1A 1 dataset

Motif DE_72h DE_72h-Ptf1A_MA1619.2 8 bp overlap

RAD21 3 datasets

ChIP H1 ENCFF698EWO 241 bp overlap

ChIP H1 ENCFF967OJF 245 bp overlap

ChIP neural cell ENCFF564MOT 522 bp overlap

ChIP neural ENCSR000BTV.REST.neural 194 bp overlap

RFX1 5 datasets

Motif DE_72h DE_72h-RFX1_MA0509.3 16 bp overlap

ChIP MCF-7 ENCFF782EZS 388 bp overlap

ChIP MCF-7 ENCFF973QAD 192 bp overlap

ChIP MCF-7 ENCSR066TET.RFX1.MCF-7 631 bp overlap

ChIP MCF-7 ENCSR788XNX.RFX1.MCF-7 266 bp overlap

Motif DE_72h DE_72h-RFX2_MA0600.3 14 bp overlap

Motif DE_72h DE_72h-RFX3_MA0798.3 16 bp overlap

Motif DE_72h DE_72h-RFX5_MA0510.3 14 bp overlap

RHOXF1 2 datasets

Motif DE_60h DE_60h-RHOXF1_MA0719.2 6 bp overlap

Motif DE_72h DE_72h-RHOXF1_MA0719.2 6 bp overlap

SCRT1 2 datasets

Motif DE_60h DE_60h-SCRT1_MA0743.3 10 bp overlap

Motif DE_72h DE_72h-SCRT1_MA0743.3 10 bp overlap

SCRT2 2 datasets

Motif DE_60h DE_60h-SCRT2_MA0744.3 10 bp overlap

Motif DE_72h DE_72h-SCRT2_MA0744.3 10 bp overlap

Motif DE_72h DE_72h-SIX1_MA1118.2 9 bp overlap

ChIP HEK GSE73865.SIX2.HEK 184 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 255 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 257 bp overlap

SMAD2_3 4 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 362 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 364 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 341 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 414 bp overlap

SMARCA4 1 dataset

ChIP hiPSC GSE124903.SMARCA4.hiPSC 240 bp overlap

SMARCC1 2 datasets

ChIP DE_D1 S15-DE-d1-BAF155-exp1 122 bp overlap

ChIP hiPSC GSE124903.SMARCC1.hiPSC 222 bp overlap

ChIP neural cell ENCFF795YGY 400 bp overlap

SNAI1 2 datasets

Motif DE_60h DE_60h-SNAI1_MA1558.2 7 bp overlap

Motif DE_72h DE_72h-SNAI1_MA1558.2 7 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 364 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 562 bp overlap

SOX21 1 dataset

Motif DE_72h DE_72h-SOX21_MA0866.1 15 bp overlap

ChIP H1 ENCFF263FUH 281 bp overlap

Motif DE_72h DE_72h-Sox1_MA0870.1 15 bp overlap

Motif DE_72h DE_72h-Spz1_MA0111.1 11 bp overlap

Stat2 1 dataset

Motif DE_72h DE_72h-Stat2_MA1623.2 10 bp overlap

TAF1 2 datasets

ChIP neural ENCSR000BTX.TAF1.neural 138 bp overlap

ChIP neural cell ENCFF468SPD 446 bp overlap

TCF12 4 datasets

Motif DE_60h DE_60h-TCF12_MA1648.2 7 bp overlap

Motif DE_72h DE_72h-TCF12_MA1648.2 7 bp overlap

ChIP H1 ENCFF203EBH 240 bp overlap

ChIP WA01 ENCSR000BIT.TCF12.WA01 127 bp overlap

TCF21 2 datasets

Motif DE_60h DE_60h-TCF21_MA1568.2 10 bp overlap

Motif DE_72h DE_72h-TCF21_MA1568.2 10 bp overlap

TCF3 2 datasets

Motif DE_60h DE_60h-TCF3_MA0522.4 7 bp overlap

Motif DE_72h DE_72h-TCF3_MA0522.4 7 bp overlap

TCF4 2 datasets

Motif DE_60h DE_60h-TCF4_MA0830.3 8 bp overlap

Motif DE_72h DE_72h-TCF4_MA0830.3 8 bp overlap

TCF7L2 1 dataset

Motif DE_72h DE_72h-TCF7L2_MA0523.2 9 bp overlap

TFAP4::FLI1 1 dataset

Motif DE_72h DE_72h-TFAP4FLI1_MA1967.2 14 bp overlap

Tcf12 1 dataset

Motif DE_72h DE_72h-Tcf12_MA0521.3 6 bp overlap

Tcf21 1 dataset

Motif DE_72h DE_72h-Tcf21_MA0832.2 10 bp overlap

Twist2 1 dataset

Motif DE_72h DE_72h-Twist2_MA0633.3 6 bp overlap

ChIP H1 ENCFF524BTL 337 bp overlap

ZBTB18 1 dataset

Motif DE_72h DE_72h-ZBTB18_MA0698.2 11 bp overlap

ZEB1 2 datasets

Motif DE_60h DE_60h-ZEB1_MA0103.4 6 bp overlap

Motif DE_72h DE_72h-ZEB1_MA0103.4 6 bp overlap

ZFP42 1 dataset

Motif DE_72h DE_72h-ZFP42_MA1651.2 13 bp overlap

ZIC1 2 datasets

Motif DE_60h DE_60h-ZIC1_MA0696.1 14 bp overlap

Motif DE_72h DE_72h-ZIC1_MA0696.1 14 bp overlap

ZIC4 2 datasets

Motif DE_60h DE_60h-ZIC4_MA0751.2 14 bp overlap

Motif DE_72h DE_72h-ZIC4_MA0751.2 14 bp overlap

Motif DE_72h DE_72h-ZIM3_MA1709.2 11 bp overlap

ZNF354C 2 datasets

Motif DE_60h DE_60h-ZNF354C_MA0130.1 6 bp overlap

Motif DE_72h DE_72h-ZNF354C_MA0130.1 6 bp overlap

ZNF418 2 datasets

Motif DE_60h DE_60h-ZNF418_MA1980.1 15 bp overlap

Motif DE_72h DE_72h-ZNF418_MA1980.1 15 bp overlap

ZNF547 1 dataset

Motif DE_72h DE_72h-ZNF547_MA2334.1 13 bp overlap

ZNF682 1 dataset

Motif DE_72h DE_72h-ZNF682_MA1599.2 11 bp overlap

ZNF768 1 dataset

Motif DE_72h DE_72h-ZNF768_MA1731.2 9 bp overlap

ZNF85 2 datasets

Motif DE_60h DE_60h-ZNF85_MA1720.2 12 bp overlap

Motif DE_72h DE_72h-ZNF85_MA1720.2 12 bp overlap

Zfp335 1 dataset

Motif DE_72h DE_72h-Zfp335_MA2002.2 7 bp overlap

Zic1::Zic2 2 datasets

Motif DE_60h DE_60h-Zic1Zic2_MA1628.2 7 bp overlap

Motif DE_72h DE_72h-Zic1Zic2_MA1628.2 7 bp overlap

Zic2 3 datasets

Motif DE_60h DE_60h-Zic2_MA1629.2 9 bp overlap

Motif DE_72h DE_72h-Zic2_MA1629.2 9 bp overlap

Motif DE_72h DE_72h-Zic2_MA1629.2 9 bp overlap

Zic3 2 datasets

Motif DE_60h DE_60h-Zic3_MA0697.3 7 bp overlap

Motif DE_72h DE_72h-Zic3_MA0697.3 7 bp overlap