chr1 : 243,489,570 – 243,490,456

886 bp 73 TFs 3 linked genes

This 886 bp open chromatin element is linked to SDCCAG8, CEP170, and AKT3 and is bound by 73 transcription factors.

Linked Genes

3 genes

Gene	Dist. to TSS	Distance	Link type
SDCCAG8	233.9 kb	Distal	Multiome
CEP170	234.6 kb	Distal	Multiome
AKT3	361.2 kb	Distal	Multiome+HiCAR

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

73 transcription factors

AFF4 1 dataset

ChIP WTC11 ENCFF556XTF 445 bp overlap

AR 1 dataset

ChIP prostate_cancer-associated-fibroblasts GSE90772.AR.prostate_cancer-associated-fibroblasts 252 bp overlap

BCOR 2 datasets

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 336 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 581 bp overlap

BRD1 2 datasets

ChIP HUES-64 GSE104059.BRD1.HUES-64 319 bp overlap

ChIP HUES-64 GSE104059.BRD1.HUES-64 326 bp overlap

BRD2 2 datasets

ChIP K-562_iBET-IFNG GSE138084.BRD2.K-562_iBET-IFNG 262 bp overlap

ChIP THP-1_iBET GSE138084.BRD2.THP-1_iBET 249 bp overlap

BRD4 2 datasets

ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 101 bp overlap

ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 195 bp overlap

CBFB 1 dataset

ChIP WTC11 ENCFF113HIY 501 bp overlap

Cebpa 3 datasets

ChIP BLaER1 ENCFF262VBH 74 bp overlap

ChIP BLaER1 ENCFF262VBH 251 bp overlap

ChIP BLaER1 ENCFF335XTP 318 bp overlap

E2F6 1 dataset

ChIP WA01 ENCSR000BSI.E2F6.WA01 122 bp overlap

ELK1::SREBF2 2 datasets

Motif DE_12h DE_12h-ELK1SREBF2_MA1933.2 15 bp overlap

Motif ES_0h ES_0h-ELK1SREBF2_MA1933.2 15 bp overlap

ERF::SREBF2 2 datasets

Motif DE_12h DE_12h-ERFSREBF2_MA1939.2 16 bp overlap

Motif ES_0h ES_0h-ERFSREBF2_MA1939.2 16 bp overlap

ETS1 1 dataset

ChIP hESC ENCSR534VHI.ETS1.hESC 141 bp overlap

ETV6 1 dataset

ChIP WTC11 ENCFF812SCD 437 bp overlap

EWSR1-FLI1 1 dataset

Motif ES_0h ES_0h-EWSR1-FLI1_MA0149.1 18 bp overlap

FEZF2 2 datasets

Motif DE_12h DE_12h-FEZF2_MA2341.1 8 bp overlap

Motif ES_0h ES_0h-FEZF2_MA2341.1 8 bp overlap

FOXK1 1 dataset

ChIP WTC11 ENCFF875IGU 391 bp overlap

FOXP4 1 dataset

ChIP WTC11 ENCFF708TAF 377 bp overlap

HNF4A 3 datasets

ChIP Hep-G2 ENCSR469FBY.HNF4A.Hep-G2 131 bp overlap

ChIP Hep-G2 ENCSR000BLF.HNF4A.Hep-G2 116 bp overlap

ChIP liver ENCFF354NRH 329 bp overlap

HNRNPL 1 dataset

ChIP Hep-G2 GSE120104.HNRNPL.Hep-G2 180 bp overlap

HNRNPLL 2 datasets

ChIP Hep-G2 GSE120104.HNRNPLL.Hep-G2 172 bp overlap

ChIP Hep-G2 ENCSR804HMZ.HNRNPLL.Hep-G2 153 bp overlap

Hand1 1 dataset

Motif ES_0h ES_0h-Hand1_MA2123.1 9 bp overlap

IKZF2 1 dataset

Motif ES_0h ES_0h-IKZF2_MA2326.1 6 bp overlap

JUN 2 datasets

ChIP ESC S34-ESC-d0-JUN-exp2 447 bp overlap

ChIP HUES-8 GSE109524.JUN.HUES-8 612 bp overlap

MED1 3 datasets

ChIP HUVEC-C_siCTL GSE124892.MED1.HUVEC-C_siCTL 226 bp overlap

ChIP HUVEC-C_siCTL GSE124892.MED1.HUVEC-C_siCTL 251 bp overlap

ChIP HUVEC-C_siERG GSE124892.MED1.HUVEC-C_siERG 206 bp overlap

MLX 1 dataset

ChIP WTC11 ENCFF823XOY 163 bp overlap

NANOG 5 datasets

ChIP GM23338 ENCFF065NZG 311 bp overlap

ChIP GM23338 ENCSR061DGF.NANOG.GM23338 258 bp overlap

ChIP HUES-8 GSE109524.NANOG.HUES-8 757 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 169 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 315 bp overlap

NCAPH2 1 dataset

ChIP IMR-90_FLAG_OIS GSE118494.NCAPH2.IMR-90_FLAG_OIS 132 bp overlap

NFATC3 1 dataset

Motif ES_0h ES_0h-NFATC3_MA0625.3 6 bp overlap

NR3C1 1 dataset

ChIP WTC11 ENCFF422OEM 444 bp overlap

Nfatc1 1 dataset

Motif ES_0h ES_0h-Nfatc1_MA0624.3 6 bp overlap

OSR2 2 datasets

Motif DE_12h DE_12h-OSR2_MA1646.2 8 bp overlap

Motif ES_0h ES_0h-OSR2_MA1646.2 8 bp overlap

POU5F1 3 datasets

ChIP GM23338 ENCFF333SNB 311 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 677 bp overlap

ChIP hESC ENCSR264RJX.POU5F1.hESC 203 bp overlap

PRDM9 1 dataset

Motif ES_0h ES_0h-PRDM9_MA1723.2 20 bp overlap

Plagl1 2 datasets

Motif DE_12h DE_12h-Plagl1_MA1615.2 8 bp overlap

Motif ES_0h ES_0h-Plagl1_MA1615.2 8 bp overlap

Prdm15 2 datasets

Motif DE_12h DE_12h-Prdm15_MA1616.2 11 bp overlap

Motif ES_0h ES_0h-Prdm15_MA1616.2 11 bp overlap

RORB 2 datasets

Motif DE_12h DE_12h-RORB_MA1150.2 10 bp overlap

Motif ES_0h ES_0h-RORB_MA1150.2 10 bp overlap

SALL3 1 dataset

ChIP hiPSC GSE104863.SALL3.hiPSC 345 bp overlap

SIX1 2 datasets

Motif DE_12h DE_12h-SIX1_MA1118.2 9 bp overlap

Motif ES_0h ES_0h-SIX1_MA1118.2 9 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8 GSE109524.SMAD2-3.HUES-8 317 bp overlap

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 443 bp overlap

SMAD2_3 1 dataset

ChIP ESC S33-ESC-d0-SMAD2_3-exp2 362 bp overlap

SMARCA4 2 datasets

ChIP hiPSC GSE124903.SMARCA4.hiPSC 255 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 313 bp overlap

SMARCB1 2 datasets

ChIP hiPSC GSE124903.SMARCB1.hiPSC 204 bp overlap

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 541 bp overlap

SMARCC1 1 dataset

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 486 bp overlap

SP1 1 dataset

ChIP liver ENCFF597LFJ 378 bp overlap

SP5 1 dataset

Motif ES_0h ES_0h-SP5_MA1965.2 6 bp overlap

SREBF2 1 dataset

ChIP HeLa-S3 ENCSR611WZO.SREBF2.HeLa-S3 130 bp overlap

STAT6 1 dataset

ChIP WTC11 ENCFF271RMR 457 bp overlap

Six4 2 datasets

Motif DE_12h DE_12h-Six4_MA2001.2 7 bp overlap

Motif ES_0h ES_0h-Six4_MA2001.2 7 bp overlap

TBP 1 dataset

ChIP hESC_8h GSE122298.TBP.hESC_8h 110 bp overlap

TEAD1 1 dataset

ChIP WTC11 ENCFF502QUV 405 bp overlap

TFAP2C 1 dataset

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 127 bp overlap

THRB 2 datasets

Motif DE_12h DE_12h-THRB_MA1575.2 17 bp overlap

Motif ES_0h ES_0h-THRB_MA1575.2 17 bp overlap

TP53 1 dataset

ChIP WTC11 ENCFF359JCU 537 bp overlap

Tfcp2l1 2 datasets

Motif DE_12h DE_12h-Tfcp2l1_MA0145.2 14 bp overlap

Motif ES_0h ES_0h-Tfcp2l1_MA0145.2 14 bp overlap

Thap11 1 dataset

Motif ES_0h ES_0h-Thap11_MA1573.2 14 bp overlap

USF1 1 dataset

ChIP WTC11 ENCFF699QGS 425 bp overlap

ZEB1 1 dataset

ChIP neuron_bipolar_doxy_4d ENCSR418KUS.ZEB1.neuron_bipolar_doxy_4d 139 bp overlap

ZFP64 2 datasets

ChIP HEK293 GSE76494.ZFP64.HEK293 170 bp overlap

ChIP Hep-G2 ENCSR487CPI.ZFP64.Hep-G2 197 bp overlap

ZKSCAN3 2 datasets

Motif DE_12h DE_12h-ZKSCAN3_MA1973.2 14 bp overlap

Motif ES_0h ES_0h-ZKSCAN3_MA1973.2 14 bp overlap

ZNF135 1 dataset

Motif ES_0h ES_0h-ZNF135_MA1587.1 14 bp overlap

ZNF184 1 dataset

ChIP K-562 ENCSR621ATC.ZNF184.K-562 216 bp overlap

ZNF232 1 dataset

ChIP WTC11 ENCFF901BGD 305 bp overlap

ZNF263 1 dataset

Motif ES_0h ES_0h-ZNF263_MA0528.3 7 bp overlap

ZNF282 2 datasets

Motif DE_12h DE_12h-ZNF282_MA1154.2 15 bp overlap

Motif ES_0h ES_0h-ZNF282_MA1154.2 15 bp overlap

ZNF530 1 dataset

Motif ES_0h ES_0h-ZNF530_MA1981.2 14 bp overlap

ZNF675 1 dataset

Motif ES_0h ES_0h-ZNF675_MA1714.2 19 bp overlap

ZNF736 1 dataset

ChIP HEK293T GSE78099.ZNF736.HEK293T 99 bp overlap

ZNF75D 1 dataset

Motif ES_0h ES_0h-ZNF75D_MA1601.2 12 bp overlap

ZNF766 2 datasets

Motif DE_12h DE_12h-ZNF766_MA2098.1 9 bp overlap

Motif ES_0h ES_0h-ZNF766_MA2098.1 9 bp overlap

ZNF816 1 dataset

Motif ES_0h ES_0h-ZNF816_MA1719.2 15 bp overlap

Zic1::Zic2 1 dataset

Motif ES_0h ES_0h-Zic1Zic2_MA1628.2 7 bp overlap

Zic2 1 dataset

Motif ES_0h ES_0h-Zic2_MA1629.2 9 bp overlap

Zic3 1 dataset

Motif ES_0h ES_0h-Zic3_MA0697.3 7 bp overlap