chr1 : 239,061,780 – 239,062,377

597 bp 83 TFs 1 linked gene

This 597 bp open chromatin element is linked to ENSG00000227854 and is bound by 83 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000227854		8.9 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

83 transcription factors

Bcl11B 1 dataset

Motif DE_12h DE_12h-Bcl11B_MA1989.2 9 bp overlap

CTCF 2 datasets

ChIP GM23338 ENCFF772DML 201 bp overlap

ChIP THP-1_macrophage_PMA GSE96800.CTCF.THP-1_macrophage_PMA 281 bp overlap

DPRX 1 dataset

Motif DE_12h DE_12h-DPRX_MA1480.2 9 bp overlap

DUXA 1 dataset

Motif DE_12h DE_12h-DUXA_MA0884.2 13 bp overlap

Dmrt1 1 dataset

Motif DE_12h DE_12h-Dmrt1_MA1603.2 9 bp overlap

EHF 1 dataset

Motif DE_12h DE_12h-EHF_MA0598.4 9 bp overlap

ELF1 1 dataset

Motif DE_12h DE_12h-ELF1_MA0473.4 9 bp overlap

ELF2 1 dataset

Motif DE_12h DE_12h-ELF2_MA1483.3 10 bp overlap

ELF3 1 dataset

Motif DE_12h DE_12h-ELF3_MA0640.3 9 bp overlap

ELK1 1 dataset

Motif DE_12h DE_12h-ELK1_MA0028.3 9 bp overlap

ERF 1 dataset

Motif DE_12h DE_12h-ERF_MA0760.2 9 bp overlap

ERF::FOXI1 1 dataset

Motif DE_12h DE_12h-ERFFOXI1_MA1935.2 10 bp overlap

ETS1 3 datasets

Motif DE_12h DE_12h-ETS1_MA0098.4 9 bp overlap

ChIP GM23338 ENCFF701IZH 377 bp overlap

ChIP hESC ENCSR534VHI.ETS1.hESC 150 bp overlap

ETS2 1 dataset

Motif DE_12h DE_12h-ETS2_MA1484.2 9 bp overlap

ETV1 1 dataset

Motif DE_12h DE_12h-ETV1_MA0761.3 9 bp overlap

ETV2 1 dataset

Motif DE_12h DE_12h-ETV2_MA0762.2 9 bp overlap

ETV2::FOXI1 1 dataset

Motif DE_12h DE_12h-ETV2FOXI1_MA1942.2 11 bp overlap

ETV3 1 dataset

Motif DE_12h DE_12h-ETV3_MA0763.2 9 bp overlap

ETV4 1 dataset

Motif DE_12h DE_12h-ETV4_MA0764.4 9 bp overlap

Elf5 1 dataset

Motif DE_12h DE_12h-Elf5_MA0136.4 8 bp overlap

Erg 1 dataset

Motif DE_12h DE_12h-Erg_MA0474.4 10 bp overlap

FEV 1 dataset

Motif DE_12h DE_12h-FEV_MA0156.4 9 bp overlap

FLI1 1 dataset

Motif DE_12h DE_12h-FLI1_MA0475.3 9 bp overlap

FLI1::FOXI1 1 dataset

Motif DE_12h DE_12h-FLI1FOXI1_MA1950.2 11 bp overlap

FOXJ2::ELF1 1 dataset

Motif DE_12h DE_12h-FOXJ2ELF1_MA1952.2 11 bp overlap

FOXO1::ELF1 1 dataset

Motif DE_12h DE_12h-FOXO1ELF1_MA1953.2 13 bp overlap

FOXO1::ELK1 1 dataset

Motif DE_12h DE_12h-FOXO1ELK1_MA1954.2 13 bp overlap

FOXO1::FLI1 1 dataset

Motif DE_12h DE_12h-FOXO1FLI1_MA1956.2 13 bp overlap

GABPA 1 dataset

Motif DE_12h DE_12h-GABPA_MA0062.4 10 bp overlap

HAND2 1 dataset

Motif DE_12h DE_12h-HAND2_MA1638.2 6 bp overlap

HNF4A 1 dataset

ChIP Caco-2_DIFF GSE23436.HNF4A.Caco-2_DIFF 110 bp overlap

IKZF1 1 dataset

Motif DE_12h DE_12h-IKZF1_MA1508.2 8 bp overlap

IKZF2 1 dataset

Motif DE_12h DE_12h-IKZF2_MA2326.1 6 bp overlap

Ikzf3 1 dataset

Motif DE_12h DE_12h-Ikzf3_MA1992.2 9 bp overlap

KDM1A 1 dataset

ChIP SH-SY5Y_B3 GSE58258.KDM1A.SH-SY5Y_B3 164 bp overlap

MAX 2 datasets

ChIP WA01 ENCSR000EUP.MAX.WA01 184 bp overlap

ChIP WTC11 ENCFF223QFY 510 bp overlap

MED26 1 dataset

ChIP HEK293T GSE121024.MED26.HEK293T 182 bp overlap

MEIS1 1 dataset

Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap

MYBL2 1 dataset

ChIP WTC11 ENCFF166TKT 416 bp overlap

MZF1 1 dataset

Motif DE_12h DE_12h-MZF1_MA0056.3 8 bp overlap

NANOG 9 datasets

ChIP GM23338 ENCFF065NZG 300 bp overlap

ChIP GM23338 ENCSR061DGF.NANOG.GM23338 180 bp overlap

ChIP HUES-8 GSE109524.NANOG.HUES-8 452 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 273 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 125 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 355 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 446 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 283 bp overlap

ChIP hESC GSE18292.NANOG.hESC 135 bp overlap

NFATC3 1 dataset

Motif DE_12h DE_12h-NFATC3_MA0625.3 6 bp overlap

NFIA 1 dataset

Motif DE_12h DE_12h-NFIA_MA0670.2 6 bp overlap

NFIX 1 dataset

Motif DE_12h DE_12h-NFIX_MA0671.2 6 bp overlap

NKX2-1 1 dataset

ChIP H9_derived-cIN GSE99937.NKX2-1.H9_derived-cIN 123 bp overlap

NR2C2 1 dataset

Motif DE_12h DE_12h-NR2C2_MA0504.2 14 bp overlap

NR2F1 1 dataset

Motif DE_12h DE_12h-NR2F1_MA0017.3 12 bp overlap

Nfatc1 1 dataset

Motif DE_12h DE_12h-Nfatc1_MA0624.3 6 bp overlap

PAX5 1 dataset

ChIP fetal_testis GSE100639.PAX5.fetal_testis 158 bp overlap

POU5F1 16 datasets

ChIP BG03 GSE21614.POU5F1.BG03 271 bp overlap

ChIP DE_D1 DED1-OCT4_Batch_II 304 bp overlap

ChIP GM23338 ENCFF333SNB 161 bp overlap

ChIP H1 ENCFF698ZAP 205 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 488 bp overlap

ChIP NCCIT GSE36134.POU5F1.NCCIT 278 bp overlap

ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 403 bp overlap

ChIP WA01 ENCSR000BMU.POU5F1.WA01 222 bp overlap

ChIP WA09 GSE105028.POU5F1.WA09 348 bp overlap

ChIP WA09_heat-shock GSE105028.POU5F1.WA09_heat-shock 331 bp overlap

ChIP hESC ENCSR264RJX.POU5F1.hESC 229 bp overlap

ChIP hESC GSE20650.POU5F1.hESC 168 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 392 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 398 bp overlap

ChIP hiPSC GSE56567.POU5F1.hiPSC 329 bp overlap

ChIP hiPSC_3s2 GSE81899.POU5F1.hiPSC_3s2 266 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 257 bp overlap

RORA 1 dataset

Motif DE_12h DE_12h-RORA_MA0072.2 11 bp overlap

RUNX1 1 dataset

ChIP THP-1 GSE79899.RUNX1.THP-1 200 bp overlap

SALL3 1 dataset

ChIP hiPSC GSE104863.SALL3.hiPSC 264 bp overlap

SMAD1 1 dataset

ChIP BG03 GSE36578.SMAD1.BG03 138 bp overlap

SMAD3 1 dataset

ChIP BG03 GSE21614.SMAD3.BG03 255 bp overlap

SMARCA4 3 datasets

ChIP WA09_heat-shock GSE105028.SMARCA4.WA09_heat-shock 292 bp overlap

ChIP hiPSC GSE124903.SMARCA4.hiPSC 319 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 462 bp overlap

SMARCB1 2 datasets

ChIP hiPSC GSE124903.SMARCB1.hiPSC 232 bp overlap

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 425 bp overlap

SMARCC1 2 datasets

ChIP hiPSC GSE124903.SMARCC1.hiPSC 311 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 399 bp overlap

SOX10 1 dataset

Motif DE_12h DE_12h-SOX10_MA0442.3 6 bp overlap

SOX15 1 dataset

Motif DE_12h DE_12h-SOX15_MA1152.2 7 bp overlap

SOX2 3 datasets

ChIP hESC GSE69479.SOX2.hESC 183 bp overlap

ChIP hESC GSE18292.SOX2.hESC 138 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 403 bp overlap

SP1 1 dataset

ChIP WTC11 ENCFF688PEU 501 bp overlap

SREBF1 1 dataset

Motif DE_12h DE_12h-SREBF1_MA0829.3 10 bp overlap

SRF 1 dataset

Motif DE_12h DE_12h-SRF_MA0083.3 16 bp overlap

Stat6 1 dataset

Motif DE_12h DE_12h-Stat6_MA0520.2 10 bp overlap

TAL1 1 dataset

ChIP PRIMA2 GSE33850.TAL1.PRIMA2 200 bp overlap

TEAD4 1 dataset

ChIP H1 ENCFF778PAX 245 bp overlap

TP53 1 dataset

ChIP IMR-90_SENES_SHLUC GSE42728.TP53.IMR-90_SENES_SHLUC 128 bp overlap

USF1 2 datasets

ChIP H1 ENCFF090WVU 241 bp overlap

ChIP WA01 ENCSR000BIU.USF1.WA01 242 bp overlap

USF2 1 dataset

ChIP WTC11 ENCFF139JAW 409 bp overlap

ZBTB21 1 dataset

ChIP WTC11 ENCFF677ZYY 342 bp overlap

ZBTB43 1 dataset

ChIP WTC11 ENCFF058JUB 421 bp overlap

ZNF175 1 dataset

Motif DE_12h DE_12h-ZNF175_MA2332.1 9 bp overlap

ZNF184 1 dataset

ChIP WTC11 ENCFF352POG 430 bp overlap

ZNF207 1 dataset

ChIP WA09 GSE118632.ZNF207.WA09 234 bp overlap

ZNF232 1 dataset

ChIP WTC11 ENCFF901BGD 414 bp overlap

ZNF382 1 dataset

Motif DE_12h DE_12h-ZNF382_MA1594.1 24 bp overlap

ZNF462 1 dataset

ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 243 bp overlap

ZNF534 1 dataset

ChIP HEK293T GSE78099.ZNF534.HEK293T 225 bp overlap

ZNF684 1 dataset

Motif DE_12h DE_12h-ZNF684_MA1600.2 14 bp overlap

ZNF708 1 dataset

Motif DE_12h DE_12h-ZNF708_MA1730.2 9 bp overlap

ZNF777 1 dataset

ChIP HEK293T GSE78099.ZNF777.HEK293T 184 bp overlap