chr15:64,780,613–64,781,099

chr15 : 64,780,613 – 64,781,099

486 bp 74 TFs 6 linked genes

This 486 bp open chromatin element is linked to 6 target genes and is bound by 74 transcription factors.

Linked Genes

6 genes

Gene	Expression	Dist. to TSS	Distance	Link type
RBPMS2		5.0 kb	Proximal	Proximity
PIF1		44.8 kb	Distal	Multiome
OAZ2		77.6 kb	Distal	Multiome
ANKDD1A		131.1 kb	Distal	Multiome
SPG21		209.1 kb	Distal	Multiome
MTFMT		248.8 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

74 transcription factors

ADNP 2 datasets

ChIP K-562 ENCSR440VKE.ADNP.K-562 303 bp overlap

ChIP K562 ENCFF492SKF 486 bp overlap

ARID1B 2 datasets

ChIP K-562 ENCSR822CCM.ARID1B.K-562 259 bp overlap

ChIP K562 ENCFF938UXQ 143 bp overlap

ASCL1 1 dataset

ChIP NCI-H82 GSE69394.ASCL1.NCI-H82 184 bp overlap

BCL11A 1 dataset

ChIP CD34_Day5_30min GSE104676.BCL11A.CD34_Day5_30min 53 bp overlap

BCOR 2 datasets

ChIP K-562 ENCSR808AKZ.BCOR.K-562 260 bp overlap

ChIP K562 ENCFF343XWA 332 bp overlap

CBFA2T2 2 datasets

ChIP K-562 ENCSR699PVC.CBFA2T2.K-562 298 bp overlap

ChIP K562 ENCFF963TXY 160 bp overlap

CBFA2T3 2 datasets

ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 354 bp overlap

ChIP K562 ENCFF673OEZ 300 bp overlap

CEBPB 1 dataset

ChIP K-562 ENCSR000BRQ.CEBPB.K-562 120 bp overlap

ChIP HAP1_clone21_CTCF-CRISPR GSE152721.CTCF.HAP1_clone21_CTCF-CRISPR 312 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF031ISE 101 bp overlap

ChIP K-562 ENCSR219BXP.DPF2.K-562 225 bp overlap

Motif DE_72h DE_72h-E2F6_MA0471.3 8 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 312 bp overlap

ESR1 4 datasets

ChIP Ishikawa ENCSR000BQR.ESR1.Ishikawa 113 bp overlap

ChIP U2OS_100nM-E2 GSE151039.ESR1.U2OS_100nM-E2 132 bp overlap

ChIP U2OS_10nM-E2 GSE151039.ESR1.U2OS_10nM-E2 138 bp overlap

ChIP U2OS_E2 GSE26110.ESR1.U2OS_E2 129 bp overlap

ESR1_Y537N 1 dataset

ChIP MCF-7_dox GSE94493.ESR1_Y537N.MCF-7_dox 169 bp overlap

ESRRA 2 datasets

ChIP K-562 ENCSR486IFJ.ESRRA.K-562 345 bp overlap

ChIP K562 ENCFF968PEP 292 bp overlap

ESRRG 1 dataset

ChIP cardiomyocyte GSE113760.ESRRG.cardiomyocyte 245 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 309 bp overlap

ChIP DE DE-FOXA2-2 449 bp overlap

FOXD3 1 dataset

Motif DE_72h DE_72h-FOXD3_MA0041.3 14 bp overlap

GATA1 6 datasets

ChIP CD34_Day7_30min GSE104676.GATA1.CD34_Day7_30min 142 bp overlap

ChIP HUDEP-2_30min GSE104676.GATA1.HUDEP-2_30min 148 bp overlap

ChIP K-562 GSE107726.GATA1.K-562 330 bp overlap

ChIP K-562 ENCSR000EFT.GATA1.K-562 118 bp overlap

ChIP K-562_dCas9-LSD1 GSE132212.GATA1.K-562_dCas9-LSD1 219 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 180 bp overlap

GATA2 4 datasets

ChIP K-562 ENCSR000DKA.GATA2.K-562 305 bp overlap

ChIP K-562 ENCSR000EWG.GATA2.K-562 122 bp overlap

ChIP LNCaP_CSFCS GSE69043.GATA2.LNCaP_CSFCS 134 bp overlap

ChIP SKH1 GSE87283.GATA2.SKH1 175 bp overlap

GATA4 3 datasets

ChIP DE DE-GATA4-1 486 bp overlap

ChIP DE DE-GATA4-2 486 bp overlap

ChIP foregut GSE117136.GATA4.foregut 268 bp overlap

GATA6 6 datasets

ChIP DE DE-GATA6-1 486 bp overlap

ChIP DE DE-GATA6-2 486 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 418 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 264 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 422 bp overlap

ChIP foregut GSE117136.GATA6.foregut 423 bp overlap

GTF2I 1 dataset

ChIP K562 ENCFF539BYI 324 bp overlap

HDAC1 3 datasets

ChIP K-562 ENCSR387UWP.HDAC1.K-562 298 bp overlap

ChIP K-562 ENCSR711VWL.HDAC1.K-562 224 bp overlap

ChIP K562 ENCFF968WBH 388 bp overlap

HDAC2 3 datasets

ChIP K-562 ENCSR893WSB.HDAC2.K-562 318 bp overlap

ChIP K-562 ENCSR075HTM.HDAC2.K-562 255 bp overlap

ChIP K562 ENCFF744ALD 327 bp overlap

HMBOX1 1 dataset

ChIP K-562 ENCSR757IIU.HMBOX1.K-562 235 bp overlap

HNF4A 2 datasets

ChIP Hep-G2 ENCSR469FBY.HNF4A.Hep-G2 136 bp overlap

ChIP gastric-epithelial-cell_OE GSE114018.HNF4A.gastric-epithelial-cell_OE 235 bp overlap

Motif DE_72h DE_72h-Hmx1_MA0896.2 9 bp overlap

Hoxa13 1 dataset

Motif DE_72h DE_72h-Hoxa13_MA0650.4 8 bp overlap

Motif DE_72h DE_72h-ISL2_MA0914.2 6 bp overlap

KDM1A 11 datasets

ChIP K-562 GSE117944.KDM1A.K-562 369 bp overlap

ChIP K-562 ENCSR360HRA.KDM1A.K-562 360 bp overlap

ChIP K-562 ENCSR908CMW.KDM1A.K-562 327 bp overlap

ChIP K-562 ENCSR000ATX.KDM1A.K-562 278 bp overlap

ChIP K-562_Wnt GSE117944.KDM1A.K-562_Wnt 284 bp overlap

ChIP K562 ENCFF128TYE 236 bp overlap

ChIP K562 ENCFF133OLU 224 bp overlap

ChIP K562 ENCFF934ZRG 423 bp overlap

ChIP SKNO-1_RN1 GSE71739.KDM1A.SKNO-1_RN1 193 bp overlap

ChIP pancreatic-progenitor_GT GSE104840.KDM1A.pancreatic-progenitor_GT 349 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.KDM1A.pancreatic-progenitor_PP1 274 bp overlap

KLF1 2 datasets

ChIP HEK293 ENCFF159QSW 193 bp overlap

ChIP HEK293 ENCSR859BMR.KLF1.HEK293 297 bp overlap

ChIP HAP1 GSE130417.KLF4.HAP1 381 bp overlap

ChIP HEP GSE52637.LDB1.HEP 176 bp overlap

ChIP CD4_Th1 GSE72266.MAF.CD4_Th1 180 bp overlap

NCOR1 1 dataset

ChIP K-562 ENCSR798ILC.NCOR1.K-562 241 bp overlap

NEUROD1 4 datasets

ChIP D283-Med GSE92582.NEUROD1.D283-Med 179 bp overlap

ChIP D341-Med_shGFP GSE92582.NEUROD1.D341-Med_shGFP 332 bp overlap

ChIP D341-Med_shNEUROD1-1154 GSE92582.NEUROD1.D341-Med_shNEUROD1-1154 168 bp overlap

ChIP D341-Med_shNEUROD1-1579 GSE92582.NEUROD1.D341-Med_shNEUROD1-1579 249 bp overlap

ChIP ProEs GSE59087.NFE2.ProEs 165 bp overlap

NFIA 2 datasets

ChIP HepG2 ENCFF815HWK 364 bp overlap

ChIP K-562 GSE97661.NFIA.K-562 317 bp overlap

NFIB 4 datasets

ChIP MCF-7 ENCFF799WGQ 106 bp overlap

ChIP MCF-7 ENCFF925CGH 382 bp overlap

ChIP MCF-7 ENCSR702BYX.NFIB.MCF-7 387 bp overlap

ChIP MCF-7 ENCSR582ZOA.NFIB.MCF-7 341 bp overlap

NFIC 4 datasets

ChIP Ishikawa ENCFF029AAD 370 bp overlap

ChIP Ishikawa ENCSR000BUT.NFIC.Ishikawa 211 bp overlap

ChIP K-562 ENCSR796ITY.NFIC.K-562 404 bp overlap

ChIP K562 ENCFF167YID 395 bp overlap

ChIP K562 ENCFF382SJS 301 bp overlap

NKX2-3 1 dataset

Motif DE_72h DE_72h-NKX2-3_MA0672.2 8 bp overlap

NKX2-4 1 dataset

Motif DE_72h DE_72h-NKX2-4_MA2003.2 8 bp overlap

NKX2-8 1 dataset

Motif DE_72h DE_72h-NKX2-8_MA0673.2 8 bp overlap

NR2F1 2 datasets

ChIP K-562 ENCSR970NKQ.NR2F1.K-562 294 bp overlap

ChIP K562 ENCFF221HJH 208 bp overlap

NR2F2 2 datasets

ChIP K-562 ENCSR000BRS.NR2F2.K-562 266 bp overlap

ChIP K562 ENCFF004YPK 297 bp overlap

NR2F6 2 datasets

ChIP K-562 ENCSR707QWA.NR2F6.K-562 254 bp overlap

ChIP K562 ENCFF674RQA 335 bp overlap

NR5A1 1 dataset

ChIP Hep-G2 ENCSR310OZS.NR5A1.Hep-G2 131 bp overlap

NR5A2 2 datasets

ChIP A-549 ENCSR190GIW.NR5A2.A-549 326 bp overlap

ChIP A549 ENCFF834RVE 408 bp overlap

Nkx3-1 1 dataset

Motif DE_72h DE_72h-Nkx3-1_MA0124.3 7 bp overlap

Nkx3-2 1 dataset

Motif DE_72h DE_72h-Nkx3-2_MA0122.4 10 bp overlap

Motif DE_72h DE_72h-PAX6_MA0069.1 14 bp overlap

POU5F1 1 dataset

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 341 bp overlap

Pparg::Rxra 1 dataset

Motif DE_72h DE_72h-PpargRxra_MA0065.3 13 bp overlap

RAD21 3 datasets

ChIP HAP1 GSE152721.RAD21.HAP1 304 bp overlap

ChIP HAP1_CTCF GSE126634.RAD21.HAP1_CTCF 373 bp overlap

ChIP HAP1_clone25 GSE152721.RAD21.HAP1_clone25 244 bp overlap

RBM25 1 dataset

ChIP K-562 ENCSR791OZM.RBM25.K-562 292 bp overlap

RCOR1 2 datasets

ChIP K562 ENCFF216EEJ 297 bp overlap

ChIP keratinocyte_diff GSE57702.RCOR1.keratinocyte_diff 303 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 453 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 386 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 330 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 346 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 486 bp overlap

ChIP K-562 ENCSR788RSW.SOX6.K-562 301 bp overlap

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 240 bp overlap

TAL1 11 datasets

ChIP K-562 GSE107726.TAL1.K-562 326 bp overlap

ChIP K-562 ENCSR106FRG.TAL1.K-562 276 bp overlap

ChIP K-562 ENCSR000EHB.TAL1.K-562 231 bp overlap

ChIP K-562_dCas9-KRAB GSE132212.TAL1.K-562_dCas9-KRAB 206 bp overlap

ChIP K-562_dCas9-LSD1 GSE132212.TAL1.K-562_dCas9-LSD1 209 bp overlap

ChIP K-562_enCRISPRi-KL GSE132212.TAL1.K-562_enCRISPRi-KL 219 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.TAL1.K-562_enCRISPRi-LK 234 bp overlap

ChIP K-562_sgGal4 GSE132212.TAL1.K-562_sgGal4 200 bp overlap

ChIP K562 ENCFF620GMX 182 bp overlap

ChIP K562 ENCFF661CCK 277 bp overlap

ChIP ProEs GSE59087.TAL1.ProEs 195 bp overlap

TCF12 2 datasets

ChIP K-562 ENCSR744WOO.TCF12.K-562 271 bp overlap

ChIP K562 ENCFF931DJY 321 bp overlap

TCF3 2 datasets

ChIP K-562 ENCSR970OJY.TCF3.K-562 231 bp overlap

ChIP K562 ENCFF319QZT 312 bp overlap

TEAD4 1 dataset

ChIP K562 ENCFF673NIK 121 bp overlap

ZBTB26 1 dataset

Motif DE_72h DE_72h-ZBTB26_MA1579.2 8 bp overlap

ZMYM3 4 datasets

ChIP Hep-G2 ENCSR848YWD.ZMYM3.Hep-G2 151 bp overlap

ChIP K-562 ENCSR102KIN.ZMYM3.K-562 322 bp overlap

ChIP K-562_Ab_JH39-2-2F10 GSE97661.ZMYM3.K-562_Ab_JH39-2-2F10 328 bp overlap

ChIP K562 ENCFF361LXT 336 bp overlap

ZNF282 1 dataset

Motif DE_72h DE_72h-ZNF282_MA1154.2 15 bp overlap

ZNF530 1 dataset

Motif DE_72h DE_72h-ZNF530_MA1981.2 14 bp overlap

ZNF629 2 datasets

ChIP Hep-G2 ENCSR363ASY.ZNF629.Hep-G2 321 bp overlap

ChIP HepG2 ENCFF490FFQ 310 bp overlap