chr11 : 95,235,300 – 95,235,760

460 bp 110 TFs 2 linked genes

This 460 bp open chromatin element is linked to LNCRNA-IUR and SESN3 and is bound by 110 transcription factors.

Linked Genes

2 genes

Gene	Expression	Dist. to TSS	Distance	Link type
LNCRNA-IUR		4.0 kb	Proximal	Proximity
SESN3		4.1 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

110 transcription factors

ALX3 1 dataset

Motif DE_12h DE_12h-ALX3_MA0634.2 6 bp overlap

ARGFX 1 dataset

Motif DE_12h DE_12h-ARGFX_MA1463.2 8 bp overlap

Alx1 1 dataset

Motif DE_12h DE_12h-Alx1_MA0854.2 8 bp overlap

Alx4 1 dataset

Motif DE_12h DE_12h-Alx4_MA0853.2 12 bp overlap

Arx 1 dataset

Motif DE_12h DE_12h-Arx_MA0874.2 10 bp overlap

BCOR 2 datasets

ChIP WA01 GSE104690.BCOR.WA01 157 bp overlap

ChIP WA01_KDM2B_KO GSE104690.BCOR.WA01_KDM2B_KO 191 bp overlap

CHD7 1 dataset

ChIP WA01 ENCSR000AVA.CHD7.WA01 260 bp overlap

CTNNB1 1 dataset

ChIP hESC_YAP-_activinA_15h GSE99202.CTNNB1.hESC_YAP-_activinA_15h 350 bp overlap

DRGX 1 dataset

Motif DE_12h DE_12h-DRGX_MA1481.2 6 bp overlap

E2F6 1 dataset

Motif DE_12h DE_12h-E2F6_MA0471.3 8 bp overlap

EMX1 1 dataset

Motif DE_12h DE_12h-EMX1_MA0612.3 6 bp overlap

EMX2 1 dataset

Motif DE_12h DE_12h-EMX2_MA0886.2 6 bp overlap

EN1 1 dataset

Motif DE_12h DE_12h-EN1_MA0027.3 6 bp overlap

EN2 1 dataset

Motif DE_12h DE_12h-EN2_MA0642.3 7 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 251 bp overlap

EP300 1 dataset

ChIP hESC GSE17917.EP300.hESC 371 bp overlap

ESX1 1 dataset

Motif DE_12h DE_12h-ESX1_MA0644.3 7 bp overlap

EVX1 1 dataset

Motif DE_12h DE_12h-EVX1_MA0887.2 6 bp overlap

EVX2 1 dataset

Motif DE_12h DE_12h-EVX2_MA0888.2 6 bp overlap

EZH2 1 dataset

ChIP DND41 ENCSR000ASW.EZH2.DND41 214 bp overlap

FOXA2 1 dataset

ChIP DE DE-FOXA2-1 246 bp overlap

FOXP1 1 dataset

ChIP H9 GSE31006.FOXP1.H9 281 bp overlap

GATA6 3 datasets

ChIP DE_D1 S09-DE-d1-GATA6-exp1 412 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 410 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 460 bp overlap

GBX1 1 dataset

Motif DE_12h DE_12h-GBX1_MA0889.2 7 bp overlap

GSX1 1 dataset

Motif DE_12h DE_12h-GSX1_MA0892.2 6 bp overlap

GSX2 1 dataset

Motif DE_12h DE_12h-GSX2_MA0893.3 7 bp overlap

HOXA1 1 dataset

Motif DE_12h DE_12h-HOXA1_MA1495.2 6 bp overlap

HOXA2 1 dataset

Motif DE_12h DE_12h-HOXA2_MA0900.3 6 bp overlap

HOXA3 1 dataset

Motif DE_12h DE_12h-HOXA3_MA2119.1 7 bp overlap

HOXB1 1 dataset

Motif DE_12h DE_12h-HOXB1_MA2093.1 7 bp overlap

HOXB2 1 dataset

Motif DE_12h DE_12h-HOXB2_MA0902.3 6 bp overlap

HOXB3 1 dataset

Motif DE_12h DE_12h-HOXB3_MA0903.2 6 bp overlap

HOXB5 1 dataset

Motif DE_12h DE_12h-HOXB5_MA0904.3 6 bp overlap

HOXC8 1 dataset

Motif DE_12h DE_12h-HOXC8_MA1505.2 6 bp overlap

HOXD3 1 dataset

Motif DE_12h DE_12h-HOXD3_MA0912.2 8 bp overlap

Hmx1 1 dataset

Motif DE_12h DE_12h-Hmx1_MA0896.2 9 bp overlap

Hmx2 1 dataset

Motif DE_12h DE_12h-Hmx2_MA0897.2 15 bp overlap

Hmx3 1 dataset

Motif DE_12h DE_12h-Hmx3_MA0898.2 9 bp overlap

IKZF1 1 dataset

Motif DE_12h DE_12h-IKZF1_MA1508.2 8 bp overlap

ISX 1 dataset

Motif DE_12h DE_12h-ISX_MA0654.2 6 bp overlap

KLF4 1 dataset

ChIP hiPSC GSE56567.KLF4.hiPSC 328 bp overlap

LBX1 1 dataset

Motif DE_12h DE_12h-LBX1_MA0618.2 7 bp overlap

LHX5 1 dataset

Motif DE_12h DE_12h-LHX5_MA1519.2 7 bp overlap

LHX6 1 dataset

Motif DE_12h DE_12h-LHX6_MA0658.2 8 bp overlap

LHX9 1 dataset

Motif DE_12h DE_12h-LHX9_MA0701.3 7 bp overlap

LMX1A 1 dataset

Motif DE_12h DE_12h-LMX1A_MA0702.3 7 bp overlap

LMX1B 1 dataset

Motif DE_12h DE_12h-LMX1B_MA0703.3 8 bp overlap

Lhx1 1 dataset

Motif DE_12h DE_12h-Lhx1_MA1518.3 10 bp overlap

Lhx4 1 dataset

Motif DE_12h DE_12h-Lhx4_MA0704.2 6 bp overlap

Lhx8 1 dataset

Motif DE_12h DE_12h-Lhx8_MA0705.2 6 bp overlap

MEF2A 1 dataset

Motif DE_12h DE_12h-MEF2A_MA0052.5 10 bp overlap

MEOX1 1 dataset

Motif DE_12h DE_12h-MEOX1_MA0661.2 7 bp overlap

MEOX2 1 dataset

Motif DE_12h DE_12h-MEOX2_MA0706.2 7 bp overlap

MGA::EVX1 1 dataset

Motif DE_12h DE_12h-MGAEVX1_MA1960.2 11 bp overlap

MIXL1 1 dataset

Motif DE_12h DE_12h-MIXL1_MA0662.2 6 bp overlap

MNX1 1 dataset

Motif DE_12h DE_12h-MNX1_MA0707.3 6 bp overlap

NANOG 10 datasets

ChIP GM23338 ENCFF065NZG 288 bp overlap

ChIP GM23338 ENCSR061DGF.NANOG.GM23338 199 bp overlap

ChIP HUES-8 GSE109524.NANOG.HUES-8 424 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 460 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 169 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 460 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 402 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 374 bp overlap

ChIP hESC GSE18292.NANOG.hESC 219 bp overlap

ChIP hESC GSE20650.NANOG.hESC 167 bp overlap

NIPBL 2 datasets

ChIP hESC_WNT3A GSE64758.NIPBL.hESC_WNT3A 299 bp overlap

ChIP hESC_WNT3A_ACTIVIN GSE64758.NIPBL.hESC_WNT3A_ACTIVIN 218 bp overlap

NKX6-1 1 dataset

Motif DE_12h DE_12h-NKX6-1_MA0674.2 7 bp overlap

NKX6-2 1 dataset

Motif DE_12h DE_12h-NKX6-2_MA0675.2 6 bp overlap

NOTO 1 dataset

Motif DE_12h DE_12h-NOTO_MA0710.2 7 bp overlap

NR4A1 1 dataset

Motif DE_12h DE_12h-NR4A1_MA1112.3 8 bp overlap

NR4A2 1 dataset

Motif DE_12h DE_12h-NR4A2_MA0160.3 8 bp overlap

NUTM1 1 dataset

ChIP embryonic-kidney_induced GSE133122.NUTM1.embryonic-kidney_induced 232 bp overlap

Nanog 1 dataset

Motif DE_12h DE_12h-Nanog_MA2339.1 7 bp overlap

ONECUT1 1 dataset

Motif DE_12h DE_12h-ONECUT1_MA0679.3 9 bp overlap

PAX3 1 dataset

Motif DE_12h DE_12h-PAX3_MA0780.1 10 bp overlap

PAX4 1 dataset

Motif DE_12h DE_12h-PAX4_MA0068.2 8 bp overlap

PDX1 1 dataset

Motif DE_12h DE_12h-PDX1_MA0132.3 6 bp overlap

PHOX2A 1 dataset

Motif DE_12h DE_12h-PHOX2A_MA0713.1 11 bp overlap

PHOX2B 2 datasets

Motif DE_12h DE_12h-PHOX2B_MA0681.3 12 bp overlap

POU5F1 10 datasets

ChIP GM23338 ENCFF333SNB 277 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 428 bp overlap

ChIP NCCIT GSE36134.POU5F1.NCCIT 282 bp overlap

ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 415 bp overlap

ChIP WA09 GSE105028.POU5F1.WA09 244 bp overlap

ChIP WA09_heat-shock GSE105028.POU5F1.WA09_heat-shock 250 bp overlap

ChIP hESC ENCSR264RJX.POU5F1.hESC 200 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 350 bp overlap

ChIP hiPSC GSE56567.POU5F1.hiPSC 151 bp overlap

ChIP hiPSC_3s2 GSE81899.POU5F1.hiPSC_3s2 267 bp overlap

POU6F1 1 dataset

Motif DE_12h DE_12h-POU6F1_MA0628.2 6 bp overlap

POU6F2 1 dataset

Motif DE_12h DE_12h-POU6F2_MA0793.2 9 bp overlap

PROP1 1 dataset

Motif DE_12h DE_12h-PROP1_MA0715.1 11 bp overlap

PRRX1 1 dataset

Motif DE_12h DE_12h-PRRX1_MA0716.2 6 bp overlap

PRRX2 1 dataset

Motif DE_12h DE_12h-PRRX2_MA0075.4 7 bp overlap

Pax7 1 dataset

Motif DE_12h DE_12h-Pax7_MA0680.3 10 bp overlap

RAD21 1 dataset

ChIP WA09_heat-shock GSE105028.RAD21.WA09_heat-shock 224 bp overlap

RAX2 1 dataset

Motif DE_12h DE_12h-RAX2_MA0717.2 6 bp overlap

RBPJ 1 dataset

Motif DE_12h DE_12h-RBPJ_MA1116.2 6 bp overlap

RNF2 1 dataset

ChIP WA09 GSE105028.RNF2.WA09 245 bp overlap

Rhox11 1 dataset

Motif DE_12h DE_12h-Rhox11_MA0629.2 9 bp overlap

SHOX 1 dataset

Motif DE_12h DE_12h-SHOX_MA0630.2 6 bp overlap

SIX2 1 dataset

Motif DE_12h DE_12h-SIX2_MA1119.2 11 bp overlap

SMARCA4 3 datasets

ChIP WA09_heat-shock GSE105028.SMARCA4.WA09_heat-shock 205 bp overlap

ChIP hiPSC GSE124903.SMARCA4.hiPSC 460 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 371 bp overlap

SMARCB1 2 datasets

ChIP hiPSC GSE124903.SMARCB1.hiPSC 460 bp overlap

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 184 bp overlap

SMARCC1 2 datasets

ChIP hiPSC GSE124903.SMARCC1.hiPSC 414 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 460 bp overlap

SOX2 2 datasets

ChIP hESC GSE18292.SOX2.hESC 155 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 190 bp overlap

SP1 1 dataset

ChIP WA01 ENCSR000BIR.SP1.WA01 161 bp overlap

Shox2 1 dataset

Motif DE_12h DE_12h-Shox2_MA0720.2 6 bp overlap

T 2 datasets

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 224 bp overlap

ChIP H9_MESODERM GSE60606.T.H9_MESODERM 300 bp overlap

TAF1 1 dataset

ChIP SK-N-SH ENCSR000BQF.TAF1.SK-N-SH 109 bp overlap

TEAD4 1 dataset

ChIP hESC GSE99202.TEAD4.hESC 342 bp overlap

TLX2 1 dataset

Motif DE_12h DE_12h-TLX2_MA1577.2 6 bp overlap

Tbx6 1 dataset

Motif DE_12h DE_12h-Tbx6_MA1567.3 9 bp overlap

UNCX 1 dataset

Motif DE_12h DE_12h-UNCX_MA0721.2 6 bp overlap

VAX1 1 dataset

Motif DE_12h DE_12h-VAX1_MA0722.2 7 bp overlap

VAX2 1 dataset

Motif DE_12h DE_12h-VAX2_MA0723.3 6 bp overlap

VSX1 1 dataset

Motif DE_12h DE_12h-VSX1_MA0725.2 7 bp overlap

VSX2 1 dataset

Motif DE_12h DE_12h-VSX2_MA0726.2 7 bp overlap

ZBTB17 1 dataset

Motif DE_12h DE_12h-ZBTB17_MA2102.1 8 bp overlap

ZNF207 1 dataset

ChIP WA09 GSE118632.ZNF207.WA09 247 bp overlap

ZNF382 1 dataset

Motif DE_12h DE_12h-ZNF382_MA1594.1 24 bp overlap

ZNF384 1 dataset

Motif DE_12h DE_12h-ZNF384_MA1125.2 8 bp overlap

ZNF462 2 datasets

ChIP GM23338 ENCFF896CCA 251 bp overlap

ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 209 bp overlap

ZNF740 1 dataset

Motif DE_12h DE_12h-ZNF740_MA0753.3 10 bp overlap

ZNF85 1 dataset

Motif DE_12h DE_12h-ZNF85_MA1720.2 12 bp overlap

ZSCAN16 1 dataset

Motif DE_12h DE_12h-ZSCAN16_MA2100.1 18 bp overlap

mix-a 1 dataset

Motif DE_12h DE_12h-mix-a_MA0621.2 7 bp overlap