chr7 : 154,917,840 – 154,919,124

1,284 bp 61 TFs 3 linked genes

This 1.3 kb open chromatin element is linked to PAXIP1-AS2, PAXIP1, and PAXIP1-DT and is bound by 61 transcription factors.

Linked Genes

3 genes

Gene	Dist. to TSS	Distance	Link type
PAXIP1-AS2	9.3 kb	Proximal	Proximity
PAXIP1	84.2 kb	Distal	Multiome
PAXIP1-DT	84.7 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

61 transcription factors

Arid3a 1 dataset

Motif DE_60h DE_60h-Arid3a_MA0151.1 6 bp overlap

BRD4 2 datasets

ChIP COLO-741 GSE73319.BRD4.COLO-741 277 bp overlap

ChIP HEK293_sgNT GSE129407.BRD4.HEK293_sgNT 218 bp overlap

CEBPB 1 dataset

ChIP K-562 ENCSR000EHE.CEBPB.K-562 152 bp overlap

CEBPG 1 dataset

Motif DE_72h DE_72h-CEBPG_MA1636.2 10 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF335XTP 285 bp overlap

Dux 1 dataset

Motif DE_60h DE_60h-Dux_MA0611.3 11 bp overlap

EOMES 2 datasets

Motif DE_60h DE_60h-EOMES_MA0800.2 9 bp overlap

ChIP hESC GSE26097.EOMES.hESC 278 bp overlap

ESR1 5 datasets

ChIP Ishikawa_DMSO_D538G_clone3 GSE132426.ESR1.Ishikawa_DMSO_D538G_clone3 221 bp overlap

ChIP Ishikawa_siETV4-72h GSE129803.ESR1.Ishikawa_siETV4-72h 304 bp overlap

ChIP Ishikawa_siNTC-72h GSE129803.ESR1.Ishikawa_siNTC-72h 342 bp overlap

ChIP Ishikawa_siNTC-96h GSE129803.ESR1.Ishikawa_siNTC-96h 318 bp overlap

ChIP MCF-7_Veh_OA GSE93510.ESR1.MCF-7_Veh_OA 247 bp overlap

EZH2 1 dataset

ChIP LNCaP GSE39459.EZH2.LNCaP 267 bp overlap

EZH2_phosphoT487 1 dataset

ChIP PC-9 ENCSR702GMW.EZH2_phosphoT487.PC-9 486 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 695 bp overlap

ChIP DE DE-FOXA2-2 1017 bp overlap

GATA4 3 datasets

ChIP DE DE-GATA4-1 662 bp overlap

ChIP DE DE-GATA4-2 816 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 289 bp overlap

GATA6 8 datasets

ChIP DE DE-GATA6-1 732 bp overlap

ChIP DE DE-GATA6-2 823 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 263 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 301 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 622 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 263 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 470 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 446 bp overlap

GLIS3 1 dataset

ChIP H9_plus GSE109562.GLIS3.H9_plus 334 bp overlap

GRHL2 4 datasets

ChIP MCF-7 GSE109820.GRHL2.MCF-7 222 bp overlap

ChIP MCF-7 GSE99680.GRHL2.MCF-7 191 bp overlap

ChIP MCF-7-WS8_VEH GSE113092.GRHL2.MCF-7-WS8_VEH 240 bp overlap

ChIP MCF-7_E2_45min GSE109820.GRHL2.MCF-7_E2_45min 179 bp overlap

HCFC1R1 1 dataset

ChIP cartilage GSE100311.HCFC1R1.cartilage 227 bp overlap

HIF3A 1 dataset

ChIP Hep-3B2-1-7 GSE129491.HIF3A.Hep-3B2-1-7 205 bp overlap

HMBOX1 2 datasets

ChIP K562 ENCFF055GAZ 159 bp overlap

ChIP K562 ENCFF317JJX 158 bp overlap

HNF1A 1 dataset

Motif DE_60h DE_60h-HNF1A_MA0046.3 13 bp overlap

HNF1B 2 datasets

Motif DE_60h DE_60h-HNF1B_MA0153.2 13 bp overlap

ChIP foregut GSE117136.HNF1B.foregut 403 bp overlap

Isl1 1 dataset

Motif DE_60h DE_60h-Isl1_MA1608.2 7 bp overlap

JUN 2 datasets

ChIP DE_D2 S02-DE-d2-JUN-exp1 574 bp overlap

ChIP Karpas-299 GSE151413.JUN.Karpas-299 184 bp overlap

KDM4C 1 dataset

ChIP KYSE-150 GSE53938.KDM4C.KYSE-150 170 bp overlap

MAX 1 dataset

ChIP K562 ENCFF398VJM 278 bp overlap

MGA 1 dataset

Motif DE_60h DE_60h-MGA_MA0801.1 8 bp overlap

MGA::EVX1 2 datasets

Motif DE_60h DE_60h-MGAEVX1_MA1960.2 11 bp overlap

MTA1 1 dataset

ChIP Hep-G2 ENCSR983KRB.MTA1.Hep-G2 169 bp overlap

MYBL1 1 dataset

Motif DE_60h DE_60h-MYBL1_MA0776.1 12 bp overlap

NFIL3 1 dataset

Motif DE_72h DE_72h-NFIL3_MA0025.3 9 bp overlap

NKX6-3 1 dataset

Motif DE_60h DE_60h-NKX6-3_MA1530.2 8 bp overlap

NRF1 1 dataset

ChIP K562 ENCFF689EWI 152 bp overlap

POU4F2 1 dataset

ChIP HNPC_DIF GSE74814.POU4F2.HNPC_DIF 70 bp overlap

Prdm15 1 dataset

Motif DE_72h DE_72h-Prdm15_MA1616.2 11 bp overlap

REST 1 dataset

ChIP colorectal-cancer_shCDH1 GSE112555.REST.colorectal-cancer_shCDH1 103 bp overlap

SOX13 1 dataset

Motif DE_72h DE_72h-SOX13_MA1120.2 7 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 449 bp overlap

SOX2 1 dataset

Motif DE_72h DE_72h-SOX2_MA0143.5 7 bp overlap

SS18-SSX 1 dataset

ChIP fibroblast_78aa-SSX-Tail GSE139053.SS18-SSX.fibroblast_78aa-SSX-Tail 69 bp overlap

Sox3 1 dataset

Motif DE_72h DE_72h-Sox3_MA0514.3 7 bp overlap

TAL1 1 dataset

ChIP PRIMA2 GSE33850.TAL1.PRIMA2 164 bp overlap

TBR1 1 dataset

Motif DE_60h DE_60h-TBR1_MA0802.2 9 bp overlap

TBX1 1 dataset

Motif DE_60h DE_60h-TBX1_MA0805.1 8 bp overlap

TBX15 1 dataset

Motif DE_60h DE_60h-TBX15_MA0803.1 8 bp overlap

TBX18 1 dataset

Motif DE_60h DE_60h-TBX18_MA1565.2 9 bp overlap

TBX19 2 datasets

Motif DE_60h DE_60h-TBX19_MA0804.2 17 bp overlap

Motif DE_72h DE_72h-TBX19_MA0804.2 17 bp overlap

TBX2 1 dataset

Motif DE_60h DE_60h-TBX2_MA0688.2 9 bp overlap

TBX20 1 dataset

Motif DE_60h DE_60h-TBX20_MA0689.1 11 bp overlap

TBX21 1 dataset

Motif DE_60h DE_60h-TBX21_MA0690.3 10 bp overlap

TBX3 1 dataset

Motif DE_60h DE_60h-TBX3_MA1566.3 9 bp overlap

TBX4 1 dataset

Motif DE_60h DE_60h-TBX4_MA0806.1 8 bp overlap

TBX5 1 dataset

Motif DE_60h DE_60h-TBX5_MA0807.1 8 bp overlap

TEAD1 1 dataset

Motif DE_72h DE_72h-TEAD1_MA0090.4 9 bp overlap

TEAD2 1 dataset

Motif DE_72h DE_72h-TEAD2_MA1121.2 7 bp overlap

TEAD3 1 dataset

Motif DE_72h DE_72h-TEAD3_MA0808.1 8 bp overlap

TEAD4 1 dataset

Motif DE_72h DE_72h-TEAD4_MA0809.3 8 bp overlap

THAP1 1 dataset

ChIP K-562 ENCSR000BNN.THAP1.K-562 115 bp overlap

Tbx6 1 dataset

Motif DE_60h DE_60h-Tbx6_MA1567.3 9 bp overlap

ZBTB7A 1 dataset

ChIP K-562 ENCSR000BME.ZBTB7A.K-562 126 bp overlap

ZNF24 1 dataset

Motif DE_60h DE_60h-ZNF24_MA1124.1 13 bp overlap

ZNF343 1 dataset

Motif DE_72h DE_72h-ZNF343_MA1711.2 16 bp overlap

ZNF652 1 dataset

Motif DE_72h DE_72h-ZNF652_MA1657.2 9 bp overlap