chr6 : 167,892,666 – 167,893,136
470 bp 86 TFs 1 linked gene
This 470 bp open chromatin element is linked to AFDN and is bound by 86 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
AFDN 542 bp At TSS Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr6:167,887,666 – 167,898,136
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
86 transcription factors
Source
Cell type
AR 1 dataset
ChIP LNCaP_GFP_shFOXA1_Ethanol GSE128883.AR.LNCaP_GFP_shFOXA1_Ethanol 64 bp overlap
ARNTL 1 dataset
ChIP U2OS_DMOG GSE85096.ARNTL.U2OS_DMOG 132 bp overlap
ATF2 1 dataset
ChIP WA01 ENCSR000BQU.ATF2.WA01 151 bp overlap
BCL6B 1 dataset
Motif ES_0h ES_0h-BCL6B_MA0731.1 17 bp overlap
BRD4 1 dataset
ChIP HEK293_sgNT GSE129407.BRD4.HEK293_sgNT 146 bp overlap
Bach1::Mafk 2 datasets
Motif DE_72h DE_72h-Bach1Mafk_MA0591.2 12 bp overlap
Motif ES_0h ES_0h-Bach1Mafk_MA0591.2 12 bp overlap
CHD7 1 dataset
ChIP H1 ENCFF126NLU 451 bp overlap
CREB1 2 datasets
ChIP GM23338 ENCFF432ZEW 227 bp overlap
ChIP GM23338 ENCSR214ZAV.CREB1.GM23338 145 bp overlap
CTCF 1 dataset
ChIP skin_lower-leg ENCSR252XWG.CTCF.skin_lower-leg 286 bp overlap
DMRTC2 1 dataset
Motif DE_72h DE_72h-DMRTC2_MA1479.2 11 bp overlap
E2F5 1 dataset
ChIP WTC11 ENCFF449LLF 371 bp overlap
E2F6 5 datasets
Motif DE_72h DE_72h-E2F6_MA0471.3 8 bp overlap
Motif ES_0h ES_0h-E2F6_MA0471.3 8 bp overlap
ChIP H1 ENCFF785DWK 207 bp overlap
ChIP K-562 ENCSR000BLI.E2F6.K-562 121 bp overlap
ChIP WA01 ENCSR000BSI.E2F6.WA01 269 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 251 bp overlap
ESR1 2 datasets
ChIP endometrioid-adenocarcinoma_tumor_2 GSE94031.ESR1.endometrioid-adenocarcinoma_tumor_2 196 bp overlap
ChIP primary-endometrium-cancer_E1_DSG GSE114737.ESR1.primary-endometrium-cancer_E1_DSG 220 bp overlap
ETV6 1 dataset
ChIP WTC11 ENCFF812SCD 325 bp overlap
EZH2 1 dataset
ChIP DND41 ENCSR000ASW.EZH2.DND41 313 bp overlap
FOS 1 dataset
ChIP endothelial_umbilical-vein ENCSR000EVU.FOS.endothelial_umbilical-vein 231 bp overlap
FOXH1 1 dataset
Motif DE_72h DE_72h-FOXH1_MA0479.2 8 bp overlap
FOXP1 1 dataset
ChIP H9 GSE31006.FOXP1.H9 134 bp overlap
GATA4 1 dataset
ChIP DE DE-GATA4-2 397 bp overlap
GATA6 2 datasets
ChIP DE DE-GATA6-1 337 bp overlap
ChIP DE DE-GATA6-2 443 bp overlap
Gfi1B 2 datasets
Motif DE_72h DE_72h-Gfi1B_MA0483.2 10 bp overlap
Motif ES_0h ES_0h-Gfi1B_MA0483.2 10 bp overlap
HDGF 1 dataset
ChIP K-562 ENCSR563YDA.HDGF.K-562 108 bp overlap
JUN 6 datasets
ChIP DE_D1 S40-DE-d1-JUN-exp2 180 bp overlap
ChIP DE_D2 S02-DE-d2-JUN-exp1 416 bp overlap
ChIP ESC S34-ESC-d0-JUN-exp2 357 bp overlap
ChIP HUES-8 GSE109524.JUN.HUES-8 326 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 311 bp overlap
ChIP Karpas-299 GSE151413.JUN.Karpas-299 337 bp overlap
JUNB 1 dataset
ChIP CFPAC-1 GSE119930.JUNB.CFPAC-1 323 bp overlap
KLF17 1 dataset
ChIP HEK293 ENCSR065WUF.KLF17.HEK293 173 bp overlap
MAF::NFE2 2 datasets
Motif DE_72h DE_72h-MAFNFE2_MA0501.2 11 bp overlap
Motif ES_0h ES_0h-MAFNFE2_MA0501.2 11 bp overlap
MAFF 1 dataset
Motif DE_72h DE_72h-MAFF_MA0495.4 11 bp overlap
MAFK 2 datasets
Motif DE_72h DE_72h-MAFK_MA0496.4 10 bp overlap
Motif ES_0h ES_0h-MAFK_MA0496.4 10 bp overlap
MAX 7 datasets
ChIP H1 ENCFF601FOM 115 bp overlap
ChIP H1 ENCFF914VQY 226 bp overlap
ChIP Ishikawa ENCFF064TDQ 342 bp overlap
ChIP Ishikawa ENCSR000BTY.MAX.Ishikawa 223 bp overlap
ChIP NCI-H2171 GSE41105.MAX.NCI-H2171 200 bp overlap
ChIP WA01 ENCSR000EUP.MAX.WA01 318 bp overlap
ChIP WTC11 ENCFF223QFY 432 bp overlap
MED1 1 dataset
ChIP hESC_PRIMED GSE69646.MED1.hESC_PRIMED 333 bp overlap
MEIS1 2 datasets
Motif DE_72h DE_72h-MEIS1_MA0498.3 5 bp overlap
Motif ES_0h ES_0h-MEIS1_MA0498.3 5 bp overlap
MITF 2 datasets
Motif DE_72h DE_72h-MITF_MA0620.4 10 bp overlap
Motif ES_0h ES_0h-MITF_MA0620.4 10 bp overlap
MXI1 2 datasets
Motif DE_72h DE_72h-MXI1_MA1108.3 6 bp overlap
Motif ES_0h ES_0h-MXI1_MA1108.3 6 bp overlap
MYC 2 datasets
ChIP H1 ENCFF794ZJT 233 bp overlap
ChIP WA01 ENCSR000EBY.MYC.WA01 187 bp overlap
Mafb 1 dataset
Motif DE_72h DE_72h-Mafb_MA0117.3 11 bp overlap
NANOG 7 datasets
ChIP GM23338 ENCFF065NZG 281 bp overlap
ChIP HUES-8 GSE109524.NANOG.HUES-8 452 bp overlap
ChIP WA01 ENCSR000BMT.NANOG.WA01 117 bp overlap
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 332 bp overlap
ChIP WA09 GSE105028.NANOG.WA09 305 bp overlap
ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 280 bp overlap
ChIP hESC GSE18292.NANOG.hESC 174 bp overlap
NRL 1 dataset
Motif DE_72h DE_72h-NRL_MA0842.3 12 bp overlap
Nfe2l2 2 datasets
Motif DE_72h DE_72h-Nfe2l2_MA0150.3 11 bp overlap
Motif ES_0h ES_0h-Nfe2l2_MA0150.3 11 bp overlap
ONECUT2 3 datasets
ChIP A-549 GSE102599.ONECUT2.A-549 223 bp overlap
ChIP A-549 GSE102599.ONECUT2.A-549 89 bp overlap
ChIP AGS_Overexpression GSE113045.ONECUT2.AGS_Overexpression 69 bp overlap
OTX2 1 dataset
ChIP WTC11 ENCFF634NAO 245 bp overlap
PKNOX2 2 datasets
Motif DE_72h DE_72h-PKNOX2_MA0783.1 12 bp overlap
Motif ES_0h ES_0h-PKNOX2_MA0783.1 12 bp overlap
POLR2A 3 datasets
ChIP H1 ENCFF566JSR 432 bp overlap
ChIP H1 ENCFF833NJP 314 bp overlap
ChIP neural cell ENCFF604SPB 141 bp overlap
POU4F2 1 dataset
ChIP HNPC_DIF GSE74814.POU4F2.HNPC_DIF 252 bp overlap
POU5F1 2 datasets
ChIP HUES-8 GSE109524.POU5F1.HUES-8 311 bp overlap
ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 137 bp overlap
RYBP 1 dataset
ChIP WA01 GSE104690.RYBP.WA01 236 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 257 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 277 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 470 bp overlap
SMAD2_3 1 dataset
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 266 bp overlap
SMARCA4 2 datasets
ChIP hiPSC GSE124903.SMARCA4.hiPSC 227 bp overlap
ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 272 bp overlap
SMARCB1 2 datasets
ChIP hiPSC GSE124903.SMARCB1.hiPSC 470 bp overlap
ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 285 bp overlap
SMARCC1 2 datasets
ChIP hiPSC GSE124903.SMARCC1.hiPSC 230 bp overlap
ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 373 bp overlap
SOX13 1 dataset
Motif DE_72h DE_72h-SOX13_MA1120.2 7 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 240 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 268 bp overlap
SOX2 5 datasets
Motif DE_72h DE_72h-SOX2_MA0143.5 7 bp overlap
ChIP HNSC GSE69479.SOX2.HNSC 162 bp overlap
ChIP LK2_GFP GSE137459.SOX2.LK2_GFP 368 bp overlap
ChIP hESC GSE18292.SOX2.hESC 96 bp overlap
ChIP hiPSC GSE56567.SOX2.hiPSC 315 bp overlap
SOX4 1 dataset
Motif DE_72h DE_72h-SOX4_MA0867.3 8 bp overlap
SOX8 1 dataset
Motif DE_72h DE_72h-SOX8_MA0868.3 7 bp overlap
SOX9 1 dataset
Motif DE_72h DE_72h-SOX9_MA0077.2 8 bp overlap
SP1 1 dataset
ChIP WA01 ENCSR000BIR.SP1.WA01 148 bp overlap
SP5 2 datasets
Motif DE_72h DE_72h-SP5_MA1965.2 6 bp overlap
Motif ES_0h ES_0h-SP5_MA1965.2 6 bp overlap
SP7 1 dataset
ChIP HEK293 ENCSR468IJT.SP7.HEK293 219 bp overlap
SRY 1 dataset
Motif DE_72h DE_72h-SRY_MA0084.2 7 bp overlap
Sox17 1 dataset
Motif DE_72h DE_72h-Sox17_MA0078.3 10 bp overlap
Sox3 1 dataset
Motif DE_72h DE_72h-Sox3_MA0514.3 7 bp overlap
Sox5 1 dataset
Motif DE_72h DE_72h-Sox5_MA0087.3 8 bp overlap
Sox6 1 dataset
Motif DE_72h DE_72h-Sox6_MA0515.1 10 bp overlap
Sox7 1 dataset
Motif DE_72h DE_72h-Sox7_MA2095.1 10 bp overlap
TAF1 1 dataset
ChIP WA01 ENCSR000BHO.TAF1.WA01 236 bp overlap
TCF3 1 dataset
ChIP NPC GSE154479.TCF3.NPC 206 bp overlap
TEAD1 1 dataset
ChIP WTC11 ENCFF502QUV 361 bp overlap
TFE3 2 datasets
Motif DE_72h DE_72h-TFE3_MA0831.3 10 bp overlap
Motif ES_0h ES_0h-TFE3_MA0831.3 10 bp overlap
TFEB 2 datasets
Motif DE_72h DE_72h-TFEB_MA0692.2 8 bp overlap
Motif ES_0h ES_0h-TFEB_MA0692.2 8 bp overlap
TFEC 2 datasets
Motif DE_72h DE_72h-TFEC_MA0871.3 8 bp overlap
Motif ES_0h ES_0h-TFEC_MA0871.3 8 bp overlap
USF1 7 datasets
Motif DE_72h DE_72h-USF1_MA0093.4 10 bp overlap
Motif ES_0h ES_0h-USF1_MA0093.4 10 bp overlap
ChIP H1 ENCFF090WVU 134 bp overlap
ChIP Ishikawa ENCFF728IEG 231 bp overlap
ChIP Ishikawa ENCSR000BSX.USF1.Ishikawa 193 bp overlap
ChIP WA01 ENCSR000BIU.USF1.WA01 236 bp overlap
ChIP WTC11 ENCFF699QGS 278 bp overlap
USF2 3 datasets
ChIP H1 ENCFF434EDF 232 bp overlap
ChIP WA01 ENCSR000ECD.USF2.WA01 166 bp overlap
ChIP WTC11 ENCFF139JAW 140 bp overlap
ZFP14 1 dataset
Motif DE_72h DE_72h-ZFP14_MA1972.1 15 bp overlap
ZIC1 1 dataset
Motif ES_0h ES_0h-ZIC1_MA0696.1 14 bp overlap
ZIC4 1 dataset
Motif ES_0h ES_0h-ZIC4_MA0751.2 14 bp overlap
ZIC5 1 dataset
Motif ES_0h ES_0h-ZIC5_MA1584.2 15 bp overlap
ZNF143 1 dataset
ChIP FLP143HA_T4 GSE39263.ZNF143.FLP143HA_T4 203 bp overlap
ZNF317 1 dataset
Motif DE_72h DE_72h-ZNF317_MA1593.2 8 bp overlap
ZNF549 1 dataset
Motif DE_72h DE_72h-ZNF549_MA1728.2 8 bp overlap
ZNF684 1 dataset
Motif DE_72h DE_72h-ZNF684_MA1600.2 14 bp overlap
ZNF708 1 dataset
Motif ES_0h ES_0h-ZNF708_MA1730.2 9 bp overlap
ZNF75A 1 dataset
Motif ES_0h ES_0h-ZNF75A_MA2097.1 12 bp overlap
ZNF75D 1 dataset
Motif ES_0h ES_0h-ZNF75D_MA1601.2 12 bp overlap
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