chr6:109,678,985–109,679,628

chr6 : 109,678,985 – 109,679,628

643 bp 55 TFs 6 linked genes

This 643 bp open chromatin element is linked to 6 target genes and is bound by 55 transcription factors.

Linked Genes

6 genes

Gene	Expression	Dist. to TSS	Distance	Link type
AK9		11.3 kb	Distal	Multiome
FIG4		12.1 kb	Distal	Multiome
ZBTB24		196.0 kb	Distal	Multiome
MICAL1		223.5 kb	Distal	Multiome
SMPD2		238.5 kb	Distal	Multiome
CD164		296.8 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

55 transcription factors

BORCS8,MEF2B 1 dataset

ChIP HepG2 ENCFF255VGS 517 bp overlap

CBFA2T3 2 datasets

ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 213 bp overlap

ChIP K562 ENCFF673OEZ 411 bp overlap

Cebpa 3 datasets

ChIP BLaER1 ENCFF093OYK 104 bp overlap

ChIP BLaER1 ENCFF335XTP 307 bp overlap

ChIP BLaER1 ENCFF460KDD 194 bp overlap

EGR1 12 datasets

ChIP GM12878 ENCFF092DJY 211 bp overlap

ChIP Hep-G2 ENCSR026GSW.EGR1.Hep-G2 266 bp overlap

ChIP HepG2 ENCFF674RQO 325 bp overlap

ChIP HepG2 ENCFF674RQO 162 bp overlap

ChIP K-562 ENCSR211LTF.EGR1.K-562 291 bp overlap

ChIP K-562 ENCSR024CNP.EGR1.K-562 247 bp overlap

ChIP K-562 ENCSR000BNE.EGR1.K-562 184 bp overlap

ChIP K562 ENCFF006PJY 245 bp overlap

ChIP K562 ENCFF113OPQ 127 bp overlap

ChIP K562 ENCFF895KGN 199 bp overlap

ChIP MCF-7 ENCFF679ZBN 341 bp overlap

ChIP MCF-7 ENCSR000BUX.EGR1.MCF-7 162 bp overlap

ChIP HEK293 ENCFF336LFH 261 bp overlap

FOXA1 20 datasets

ChIP 22Rv1_CST GSE123618.FOXA1.22Rv1_CST 224 bp overlap

ChIP HepG2 ENCFF207NVJ 185 bp overlap

ChIP HepG2 ENCFF361KNY 133 bp overlap

ChIP HepG2 ENCFF740VZW 174 bp overlap

ChIP LNCaP_L388M_shFOXA1 GSE128883.FOXA1.LNCaP_L388M_shFOXA1 165 bp overlap

ChIP LNCaP_S2101-4H GSE114266.FOXA1.LNCaP_S2101-4H 358 bp overlap

ChIP MCF-7 GSE140185.FOXA1.MCF-7 209 bp overlap

ChIP MCF-7 GSE59530.FOXA1.MCF-7 218 bp overlap

ChIP MCF-7 ERP001226.FOXA1.MCF-7 133 bp overlap

ChIP MCF-7-TAMR-1_4OH-Tam GSE75201.FOXA1.MCF-7-TAMR-1_4OH-Tam 102 bp overlap

ChIP MCF-7_4OH-Tam GSE75201.FOXA1.MCF-7_4OH-Tam 123 bp overlap

ChIP MCF-7_DOX-neg GSE124654.FOXA1.MCF-7_DOX-neg 148 bp overlap

ChIP MCF-7_E2 GSE23852.FOXA1.MCF-7_E2 132 bp overlap

ChIP MCF-7_E2 GSE59530.FOXA1.MCF-7_E2 129 bp overlap

ChIP MCF-7_E2_TNF GSE59530.FOXA1.MCF-7_E2_TNF 219 bp overlap

ChIP MCF-7_TAMR_E2_TAM ERP000380.FOXA1.MCF-7_TAMR_E2_TAM 135 bp overlap

ChIP MCF-7_TNF GSE59530.FOXA1.MCF-7_TNF 182 bp overlap

ChIP NCI-H3122 GSE39998.FOXA1.NCI-H3122 154 bp overlap

ChIP breast-cancer_Veh-2856 GSE128018.FOXA1.breast-cancer_Veh-2856 253 bp overlap

ChIP breast_tumor_Male_14 GSE104399.FOXA1.breast_tumor_Male_14 298 bp overlap

FOXA2 6 datasets

ChIP DE DE-FOXA2-1 558 bp overlap

ChIP DE DE-FOXA2-2 598 bp overlap

ChIP HepG2 ENCFF533COJ 145 bp overlap

ChIP HepG2 ENCFF570ABM 215 bp overlap

ChIP HepG2 ENCFF894AYY 226 bp overlap

ChIP colorectal-cancer_type-C GSE106921.FOXA2.colorectal-cancer_type-C 223 bp overlap

FOXA3 3 datasets

ChIP HepG2 ENCFF005KGL 156 bp overlap

ChIP K562 ENCFF348SOM 431 bp overlap

ChIP K562 ENCFF781VSC 341 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 388 bp overlap

ChIP DE DE-GATA4-2 400 bp overlap

GATA6 8 datasets

ChIP DE DE-GATA6-1 428 bp overlap

ChIP DE DE-GATA6-2 438 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 487 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 422 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 480 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 456 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 267 bp overlap

ChIP foregut GSE117136.GATA6.foregut 261 bp overlap

HOXA3 1 dataset

ChIP HepG2 ENCFF374TCI 477 bp overlap

IKZF1 1 dataset

ChIP GM12878 ENCFF753XDO 432 bp overlap

ChIP DE_D1 S08-DE-d1-JUN-exp1 296 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 326 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 539 bp overlap

ChIP MDA-BoM-1833 GSE112444.JUN.MDA-BoM-1833 181 bp overlap

KMT2B 2 datasets

ChIP HepG2 ENCFF675TEK 557 bp overlap

ChIP HepG2 ENCFF675TEK 163 bp overlap

MLLT1 1 dataset

ChIP GM12878 ENCFF995GXC 424 bp overlap

MNX1 2 datasets

ChIP Hep-G2 ENCSR108MKR.MNX1.Hep-G2 156 bp overlap

ChIP HepG2 ENCFF938KYA 551 bp overlap

ChIP HepG2 ENCFF038CCB 551 bp overlap

ChIP HepG2 ENCFF575FXK 502 bp overlap

ChIP HepG2 ENCFF815HWK 239 bp overlap

NFKB1 1 dataset

ChIP L1236 GSE63736.NFKB1.L1236 98 bp overlap

PATZ1 1 dataset

ChIP HepG2 ENCFF723PFC 401 bp overlap

PAXIP1 1 dataset

ChIP HepG2 ENCFF526NOJ 489 bp overlap

ChIP HepG2 ENCFF065NWR 568 bp overlap

POU5F1 1 dataset

ChIP DE_D1 DED1-OCT4_Batch_II 359 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 307 bp overlap

PRDM10 1 dataset

ChIP HEK293 ENCFF145WQQ 212 bp overlap

RBBP5 3 datasets

ChIP H1 ENCFF905HFL 357 bp overlap

ChIP H1 ENCFF905HFL 562 bp overlap

ChIP WA01 ENCSR000AQC.RBBP5.WA01 207 bp overlap

RELA 3 datasets

ChIP CD4_Th1_DMSO GSE62482.RELA.CD4_Th1_DMSO 160 bp overlap

ChIP GM12891 ENCSR000EAI.RELA.GM12891 155 bp overlap

ChIP IMR-90_TNF GSE43070.RELA.IMR-90_TNF 163 bp overlap

ChIP GM12878 ENCSR387QUV.RELB.GM12878 247 bp overlap

SALL1 1 dataset

ChIP HepG2 ENCFF426MCK 420 bp overlap

SAP130 1 dataset

ChIP HepG2 ENCFF892EHZ 523 bp overlap

SIN3A 1 dataset

ChIP Hep-G2 ENCSR000BGL.SIN3A.Hep-G2 88 bp overlap

SMAD2_3 4 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 356 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 543 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 385 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 397 bp overlap

SMAD7 2 datasets

ChIP HepG2 ENCFF850FXR 457 bp overlap

ChIP HepG2 ENCFF850FXR 413 bp overlap

SMARCA4 1 dataset

ChIP hiPSC GSE124903.SMARCA4.hiPSC 177 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 225 bp overlap

SOX6 2 datasets

ChIP HepG2 ENCFF767OCK 572 bp overlap

ChIP HepG2 ENCFF767OCK 441 bp overlap

ChIP H1 ENCFF263FUH 321 bp overlap

ChIP WA01 ENCSR000BIR.SP1.WA01 130 bp overlap

ChIP HepG2 ENCFF931FHV 351 bp overlap

ChIP WA01 ENCSR000BHO.TAF1.WA01 183 bp overlap

THAP9 1 dataset

ChIP HepG2 ENCFF687WSR 627 bp overlap

XRCC5 1 dataset

ChIP HepG2 ENCFF680LVJ 341 bp overlap

YY1 11 datasets

ChIP GM12878 ENCFF908JTL 114 bp overlap

ChIP GM12891 ENCFF460SIS 325 bp overlap

ChIP GM12891 ENCSR000BKJ.YY1.GM12891 113 bp overlap

ChIP GM12892 ENCFF802MHJ 317 bp overlap

ChIP GM12892 ENCSR000BLT.YY1.GM12892 124 bp overlap

ChIP H1 ENCFF524BTL 337 bp overlap

ChIP Hep-G2_NC GSE120104.YY1.Hep-G2_NC 356 bp overlap

ChIP HepG2 ENCFF956MUY 377 bp overlap

ChIP NT2-D1 ENCSR000EXG.YY1.NT2-D1 133 bp overlap

ChIP NT2/D1 ENCFF999MII 325 bp overlap

ChIP WA01 ENCSR000BKD.YY1.WA01 140 bp overlap

ZBTB6 3 datasets

ChIP HEK293 ENCFF881ECZ 331 bp overlap

ChIP HEK293 ENCSR619OUC.ZBTB6.HEK293 201 bp overlap

ChIP HEK293 GSE76494.ZBTB6.HEK293 163 bp overlap

ZFHX2 1 dataset

ChIP HEK293 ENCFF167TUA 358 bp overlap

ChIP HepG2 ENCFF016NZF 418 bp overlap

ChIP HepG2 ENCFF016NZF 620 bp overlap

ZIC2 2 datasets

ChIP HEK293 ENCFF033NQQ 301 bp overlap

ChIP HEK293 ENCFF033NQQ 192 bp overlap

ZNF148 2 datasets

ChIP K-562 GSE121133.ZNF148.K-562 201 bp overlap

ChIP K562 ENCFF352SDL 621 bp overlap

ZNF217 1 dataset

ChIP Hep-G2 ENCSR055FQB.ZNF217.Hep-G2 145 bp overlap

ZNF281 3 datasets

ChIP HepG2 ENCFF585QNU 154 bp overlap

ChIP K-562 GSE121133.ZNF281.K-562 245 bp overlap

ChIP K562 ENCFF594VNM 471 bp overlap

ZNF398 1 dataset

ChIP HEK293 ENCSR676ZEF.ZNF398.HEK293 237 bp overlap

ZNF407 1 dataset

ChIP HepG2 ENCFF537FDC 452 bp overlap

ZNF574 1 dataset

ChIP HepG2 ENCFF206MMY 552 bp overlap

ZNF687 1 dataset

ChIP HepG2 ENCFF653WIX 531 bp overlap

ZSCAN16 3 datasets

ChIP HEK293 ENCFF533NFT 215 bp overlap

ChIP HEK293 ENCSR864VJE.ZSCAN16.HEK293 282 bp overlap

ChIP HEK293 GSE76494.ZSCAN16.HEK293 148 bp overlap