chr5 : 176,238,236 – 176,238,453
217 bp 71 TFs 1 linked gene
This 217 bp open chromatin element is linked to SIMC1 and is bound by 71 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
SIMC1 at TSS At TSS Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr5:176,233,236 – 176,243,453
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
71 transcription factors
Source
Cell type
ATF6 1 dataset
Motif DE_24h DE_24h-ATF6_MA1466.2 13 bp overlap
Ahr::Arnt 1 dataset
Motif DE_24h DE_24h-AhrArnt_MA0006.2 5 bp overlap
BRD4 2 datasets
ChIP MCF-10A ERP003925.BRD4.MCF-10A 193 bp overlap
ChIP hESC GSE33281.BRD4.hESC 71 bp overlap
CREB3L1 1 dataset
Motif DE_24h DE_24h-CREB3L1_MA0839.2 13 bp overlap
CXXC5 1 dataset
ChIP K562 ENCFF497CZN 113 bp overlap
Cebpa 1 dataset
ChIP BLaER1 ENCFF460KDD 86 bp overlap
E2F6 3 datasets
ChIP A549 ENCFF550XVR 217 bp overlap
ChIP H1 ENCFF785DWK 52 bp overlap
ChIP K-562 ENCSR000BLI.E2F6.K-562 97 bp overlap
EGR1 1 dataset
ChIP HCT116 ENCFF456NPQ 186 bp overlap
ERG 3 datasets
ChIP K-562 GSE23730.ERG.K-562 168 bp overlap
ChIP K-562_DOX GSE23730.ERG.K-562_DOX 157 bp overlap
ChIP MCF-7 GSE23730.ERG.MCF-7 89 bp overlap
ETV5::FOXO1 1 dataset
Motif DE_24h DE_24h-ETV5FOXO1_MA1947.2 10 bp overlap
GLIS1 4 datasets
Motif DE_12h DE_12h-GLIS1_MA0735.2 15 bp overlap
Motif DE_24h DE_24h-GLIS1_MA0735.2 15 bp overlap
Motif DE_48h DE_48h-GLIS1_MA0735.2 15 bp overlap
Motif DE_72h DE_72h-GLIS1_MA0735.2 15 bp overlap
HMGXB4 1 dataset
ChIP WTC11 ENCFF962POR 217 bp overlap
IKZF1 1 dataset
Motif DE_24h DE_24h-IKZF1_MA1508.2 8 bp overlap
KDM4A 1 dataset
ChIP H1 ENCFF078LED 217 bp overlap
KLF1 5 datasets
Motif DE_24h DE_24h-KLF1_MA0493.3 8 bp overlap
Motif DE_24h DE_24h-KLF1_MA0493.3 8 bp overlap
Motif DE_24h DE_24h-KLF1_MA0493.3 8 bp overlap
Motif DE_48h DE_48h-KLF1_MA0493.3 8 bp overlap
Motif DE_72h DE_72h-KLF1_MA0493.3 8 bp overlap
KLF10 7 datasets
Motif DE_24h DE_24h-KLF10_MA1511.2 9 bp overlap
Motif DE_24h DE_24h-KLF10_MA1511.2 9 bp overlap
Motif DE_24h DE_24h-KLF10_MA1511.2 9 bp overlap
Motif DE_48h DE_48h-KLF10_MA1511.2 9 bp overlap
Motif DE_48h DE_48h-KLF10_MA1511.2 9 bp overlap
Motif DE_72h DE_72h-KLF10_MA1511.2 9 bp overlap
Motif DE_72h DE_72h-KLF10_MA1511.2 9 bp overlap
KLF11 3 datasets
Motif DE_24h DE_24h-KLF11_MA1512.2 10 bp overlap
Motif DE_48h DE_48h-KLF11_MA1512.2 10 bp overlap
Motif DE_72h DE_72h-KLF11_MA1512.2 10 bp overlap
KLF12 7 datasets
Motif DE_24h DE_24h-KLF12_MA0742.2 9 bp overlap
Motif DE_24h DE_24h-KLF12_MA0742.2 9 bp overlap
Motif DE_24h DE_24h-KLF12_MA0742.2 9 bp overlap
Motif DE_48h DE_48h-KLF12_MA0742.2 9 bp overlap
Motif DE_48h DE_48h-KLF12_MA0742.2 9 bp overlap
Motif DE_72h DE_72h-KLF12_MA0742.2 9 bp overlap
Motif DE_72h DE_72h-KLF12_MA0742.2 9 bp overlap
KLF14 7 datasets
Motif DE_24h DE_24h-KLF14_MA0740.2 9 bp overlap
Motif DE_24h DE_24h-KLF14_MA0740.2 9 bp overlap
Motif DE_24h DE_24h-KLF14_MA0740.2 9 bp overlap
Motif DE_48h DE_48h-KLF14_MA0740.2 9 bp overlap
Motif DE_48h DE_48h-KLF14_MA0740.2 9 bp overlap
Motif DE_72h DE_72h-KLF14_MA0740.2 9 bp overlap
Motif DE_72h DE_72h-KLF14_MA0740.2 9 bp overlap
KLF15 5 datasets
Motif DE_24h DE_24h-KLF15_MA1513.2 8 bp overlap
Motif DE_24h DE_24h-KLF15_MA1513.2 8 bp overlap
Motif DE_24h DE_24h-KLF15_MA1513.2 8 bp overlap
Motif DE_48h DE_48h-KLF15_MA1513.2 8 bp overlap
Motif DE_72h DE_72h-KLF15_MA1513.2 8 bp overlap
KLF16 3 datasets
Motif DE_24h DE_24h-KLF16_MA0741.1 11 bp overlap
Motif DE_48h DE_48h-KLF16_MA0741.1 11 bp overlap
Motif DE_72h DE_72h-KLF16_MA0741.1 11 bp overlap
KLF2 5 datasets
Motif DE_24h DE_24h-KLF2_MA1515.2 8 bp overlap
Motif DE_24h DE_24h-KLF2_MA1515.2 8 bp overlap
Motif DE_24h DE_24h-KLF2_MA1515.2 8 bp overlap
Motif DE_48h DE_48h-KLF2_MA1515.2 8 bp overlap
Motif DE_72h DE_72h-KLF2_MA1515.2 8 bp overlap
KLF3 1 dataset
Motif DE_24h DE_24h-KLF3_MA1516.2 10 bp overlap
KLF4 5 datasets
Motif DE_24h DE_24h-KLF4_MA0039.5 8 bp overlap
Motif DE_24h DE_24h-KLF4_MA0039.5 8 bp overlap
Motif DE_24h DE_24h-KLF4_MA0039.5 8 bp overlap
Motif DE_48h DE_48h-KLF4_MA0039.5 8 bp overlap
Motif DE_72h DE_72h-KLF4_MA0039.5 8 bp overlap
KLF5 5 datasets
Motif DE_24h DE_24h-KLF5_MA0599.1 10 bp overlap
Motif DE_24h DE_24h-KLF5_MA0599.1 10 bp overlap
Motif DE_24h DE_24h-KLF5_MA0599.1 10 bp overlap
Motif DE_48h DE_48h-KLF5_MA0599.1 10 bp overlap
Motif DE_72h DE_72h-KLF5_MA0599.1 10 bp overlap
KLF6 3 datasets
Motif DE_24h DE_24h-KLF6_MA1517.2 9 bp overlap
Motif DE_48h DE_48h-KLF6_MA1517.2 9 bp overlap
Motif DE_72h DE_72h-KLF6_MA1517.2 9 bp overlap
KLF7 5 datasets
Motif DE_24h DE_24h-KLF7_MA1959.2 8 bp overlap
Motif DE_24h DE_24h-KLF7_MA1959.2 8 bp overlap
Motif DE_24h DE_24h-KLF7_MA1959.2 8 bp overlap
Motif DE_48h DE_48h-KLF7_MA1959.2 8 bp overlap
Motif DE_72h DE_72h-KLF7_MA1959.2 8 bp overlap
KLF9 4 datasets
Motif DE_24h DE_24h-KLF9_MA1107.3 11 bp overlap
Motif DE_48h DE_48h-KLF9_MA1107.3 11 bp overlap
Motif DE_72h DE_72h-KLF9_MA1107.3 11 bp overlap
ChIP MCF-7 ENCFF618FCM 217 bp overlap
L3MBTL2 1 dataset
ChIP K562 ENCFF320EQC 100 bp overlap
MAX 9 datasets
ChIP A549 ENCFF310XGQ 217 bp overlap
ChIP H1 ENCFF914VQY 212 bp overlap
ChIP HCT116 ENCFF810LEN 217 bp overlap
ChIP HepG2 ENCFF507HCX 127 bp overlap
ChIP HepG2 ENCFF507HCX 217 bp overlap
ChIP K562 ENCFF524IJO 52 bp overlap
ChIP MCF-7 ENCFF169IXS 217 bp overlap
ChIP NCI-H2171 GSE36354.MAX.NCI-H2171 216 bp overlap
ChIP WTC11 ENCFF223QFY 217 bp overlap
MAZ 2 datasets
ChIP K562 ENCFF333ZIV 146 bp overlap
ChIP K562 ENCFF809XHP 217 bp overlap
MED1 1 dataset
ChIP MM1-S_JQ1_500NM GSE42355.MED1.MM1-S_JQ1_500NM 168 bp overlap
MGA 2 datasets
ChIP HepG2 ENCFF057YJE 217 bp overlap
ChIP K562 ENCFF140CEX 217 bp overlap
NR2C2 1 dataset
ChIP K562 ENCFF750AXF 217 bp overlap
NR2F2 1 dataset
ChIP MCF-7 ENCFF329FZB 217 bp overlap
OSR2 1 dataset
Motif DE_24h DE_24h-OSR2_MA1646.2 8 bp overlap
PATZ1 8 datasets
Motif DE_24h DE_24h-PATZ1_MA1961.2 11 bp overlap
Motif DE_24h DE_24h-PATZ1_MA1961.2 11 bp overlap
Motif DE_24h DE_24h-PATZ1_MA1961.2 11 bp overlap
Motif DE_24h DE_24h-PATZ1_MA1961.2 11 bp overlap
Motif DE_48h DE_48h-PATZ1_MA1961.2 11 bp overlap
Motif DE_48h DE_48h-PATZ1_MA1961.2 11 bp overlap
Motif DE_72h DE_72h-PATZ1_MA1961.2 11 bp overlap
Motif DE_72h DE_72h-PATZ1_MA1961.2 11 bp overlap
POLR2A 2 datasets
ChIP GM23338 ENCFF450WCS 217 bp overlap
ChIP spleen ENCFF706IUS 158 bp overlap
POU5F1_M 1 dataset
ChIP DE_D1 DED1-OCT4-M_Batch_II 107 bp overlap
RBFOX2 1 dataset
ChIP K562 ENCFF967GRF 127 bp overlap
RBPJ 1 dataset
Motif DE_24h DE_24h-RBPJ_MA1116.2 6 bp overlap
SMAD2_3 1 dataset
ChIP ESC S23-ESC-d0-SMAD2_3-exp1 85 bp overlap
SMAD4 1 dataset
ChIP K562 ENCFF628RBP 217 bp overlap
SP1 9 datasets
Motif DE_24h DE_24h-SP1_MA0079.5 9 bp overlap
Motif DE_24h DE_24h-SP1_MA0079.5 9 bp overlap
Motif DE_24h DE_24h-SP1_MA0079.5 9 bp overlap
Motif DE_24h DE_24h-SP1_MA0079.5 9 bp overlap
Motif DE_48h DE_48h-SP1_MA0079.5 9 bp overlap
Motif DE_48h DE_48h-SP1_MA0079.5 9 bp overlap
Motif DE_72h DE_72h-SP1_MA0079.5 9 bp overlap
Motif DE_72h DE_72h-SP1_MA0079.5 9 bp overlap
ChIP WTC11 ENCFF688PEU 217 bp overlap
SP2 7 datasets
Motif DE_24h DE_24h-SP2_MA0516.3 9 bp overlap
Motif DE_24h DE_24h-SP2_MA0516.3 9 bp overlap
Motif DE_24h DE_24h-SP2_MA0516.3 9 bp overlap
Motif DE_48h DE_48h-SP2_MA0516.3 9 bp overlap
Motif DE_48h DE_48h-SP2_MA0516.3 9 bp overlap
Motif DE_72h DE_72h-SP2_MA0516.3 9 bp overlap
Motif DE_72h DE_72h-SP2_MA0516.3 9 bp overlap
SP3 7 datasets
Motif DE_24h DE_24h-SP3_MA0746.3 11 bp overlap
Motif DE_24h DE_24h-SP3_MA0746.3 11 bp overlap
Motif DE_24h DE_24h-SP3_MA0746.3 11 bp overlap
Motif DE_48h DE_48h-SP3_MA0746.3 11 bp overlap
Motif DE_48h DE_48h-SP3_MA0746.3 11 bp overlap
Motif DE_72h DE_72h-SP3_MA0746.3 11 bp overlap
Motif DE_72h DE_72h-SP3_MA0746.3 11 bp overlap
SP4 7 datasets
Motif DE_24h DE_24h-SP4_MA0685.2 9 bp overlap
Motif DE_24h DE_24h-SP4_MA0685.2 9 bp overlap
Motif DE_24h DE_24h-SP4_MA0685.2 9 bp overlap
Motif DE_48h DE_48h-SP4_MA0685.2 9 bp overlap
Motif DE_48h DE_48h-SP4_MA0685.2 9 bp overlap
Motif DE_72h DE_72h-SP4_MA0685.2 9 bp overlap
Motif DE_72h DE_72h-SP4_MA0685.2 9 bp overlap
SP8 3 datasets
Motif DE_24h DE_24h-SP8_MA0747.2 11 bp overlap
Motif DE_48h DE_48h-SP8_MA0747.2 11 bp overlap
Motif DE_72h DE_72h-SP8_MA0747.2 11 bp overlap
SP9 7 datasets
Motif DE_24h DE_24h-SP9_MA1564.2 10 bp overlap
Motif DE_24h DE_24h-SP9_MA1564.2 10 bp overlap
Motif DE_24h DE_24h-SP9_MA1564.2 10 bp overlap
Motif DE_48h DE_48h-SP9_MA1564.2 10 bp overlap
Motif DE_48h DE_48h-SP9_MA1564.2 10 bp overlap
Motif DE_72h DE_72h-SP9_MA1564.2 10 bp overlap
Motif DE_72h DE_72h-SP9_MA1564.2 10 bp overlap
Stat5b 1 dataset
Motif DE_24h DE_24h-Stat5b_MA1625.2 9 bp overlap
TFAP4 1 dataset
ChIP K562 ENCFF727PXG 217 bp overlap
TFDP1 1 dataset
ChIP K562 ENCFF584VSB 217 bp overlap
TGIF2 1 dataset
ChIP WTC11 ENCFF649SHI 217 bp overlap
TRIM24 1 dataset
ChIP LNCaP-abl_ETOH GSE69331.TRIM24.LNCaP-abl_ETOH 217 bp overlap
Thap11 1 dataset
Motif DE_24h DE_24h-Thap11_MA1573.2 14 bp overlap
VEZF1 1 dataset
ChIP K562 ENCFF053XDV 217 bp overlap
YY1 1 dataset
ChIP K-562 ENCSR000BMH.YY1.K-562 94 bp overlap
ZBED4 8 datasets
Motif DE_24h DE_24h-ZBED4_MA2328.1 10 bp overlap
Motif DE_24h DE_24h-ZBED4_MA2328.1 10 bp overlap
Motif DE_24h DE_24h-ZBED4_MA2328.1 10 bp overlap
Motif DE_24h DE_24h-ZBED4_MA2328.1 10 bp overlap
Motif DE_48h DE_48h-ZBED4_MA2328.1 10 bp overlap
Motif DE_48h DE_48h-ZBED4_MA2328.1 10 bp overlap
Motif DE_72h DE_72h-ZBED4_MA2328.1 10 bp overlap
Motif DE_72h DE_72h-ZBED4_MA2328.1 10 bp overlap
ZBTB26 1 dataset
ChIP HEK293 ENCFF752TCU 217 bp overlap
ZBTB7A 2 datasets
ChIP Ishikawa ENCFF191NFH 217 bp overlap
ChIP K-562 ENCSR000BME.ZBTB7A.K-562 150 bp overlap
ZFX 2 datasets
ChIP HepG2 ENCFF016NZF 217 bp overlap
ChIP K562 ENCFF536AJO 217 bp overlap
ZNF148 7 datasets
Motif DE_24h DE_24h-ZNF148_MA1653.2 10 bp overlap
Motif DE_24h DE_24h-ZNF148_MA1653.2 10 bp overlap
Motif DE_24h DE_24h-ZNF148_MA1653.2 10 bp overlap
Motif DE_48h DE_48h-ZNF148_MA1653.2 10 bp overlap
Motif DE_48h DE_48h-ZNF148_MA1653.2 10 bp overlap
Motif DE_72h DE_72h-ZNF148_MA1653.2 10 bp overlap
Motif DE_72h DE_72h-ZNF148_MA1653.2 10 bp overlap
ZNF18 1 dataset
ChIP HEK293 ENCFF066NGR 128 bp overlap
ZNF362 1 dataset
ChIP HepG2 ENCFF256AZN 217 bp overlap
ZNF384 1 dataset
Motif DE_24h DE_24h-ZNF384_MA1125.2 8 bp overlap
ZNF460 3 datasets
Motif DE_24h DE_24h-ZNF460_MA1596.1 16 bp overlap
Motif DE_48h DE_48h-ZNF460_MA1596.1 16 bp overlap
Motif DE_72h DE_72h-ZNF460_MA1596.1 16 bp overlap
ZNF610 1 dataset
Motif DE_24h DE_24h-ZNF610_MA1713.2 10 bp overlap
ZNF675 1 dataset
Motif DE_24h DE_24h-ZNF675_MA1714.2 19 bp overlap
ZNF682 4 datasets
Motif DE_24h DE_24h-ZNF682_MA1599.2 11 bp overlap
Motif DE_24h DE_24h-ZNF682_MA1599.2 11 bp overlap
Motif DE_48h DE_48h-ZNF682_MA1599.2 11 bp overlap
Motif DE_72h DE_72h-ZNF682_MA1599.2 11 bp overlap
ZNF687 1 dataset
ChIP HepG2 ENCFF653WIX 217 bp overlap
ZNF93 5 datasets
Motif DE_24h DE_24h-ZNF93_MA1721.2 14 bp overlap
Motif DE_24h DE_24h-ZNF93_MA1721.2 14 bp overlap
Motif DE_24h DE_24h-ZNF93_MA1721.2 14 bp overlap
Motif DE_48h DE_48h-ZNF93_MA1721.2 14 bp overlap
Motif DE_72h DE_72h-ZNF93_MA1721.2 14 bp overlap
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