chr4 : 77,084,016 – 77,084,805
789 bp 93 TFs 4 linked genes
This 789 bp open chromatin element is linked to 4 target genes and is bound by 93 transcription factors.
Linked Genes
4 genes
Distance
Link type
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
ENSG00000289496 8.0 kb Proximal Proximity
CCNI 9.1 kb Proximal Proximity
CCNG2 72.8 kb Distal Multiome
SEPTIN11 134.6 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr4:77,079,016 – 77,089,805
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
93 transcription factors
Source
Cell type
ARID1B 2 datasets
ChIP K-562 ENCSR822CCM.ARID1B.K-562 348 bp overlap
ChIP K562 ENCFF938UXQ 541 bp overlap
ATF1 1 dataset
ChIP K-562 ENCSR091GVJ.ATF1.K-562 467 bp overlap
BRD3 1 dataset
ChIP H-1_DE GSE126661.BRD3.H-1_DE 268 bp overlap
CBFA2T2 1 dataset
ChIP K562 ENCFF963TXY 381 bp overlap
CBFA2T3 2 datasets
ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 316 bp overlap
ChIP K562 ENCFF673OEZ 411 bp overlap
CBX2 1 dataset
ChIP K-562_HS GSE121182.CBX2.K-562_HS 228 bp overlap
CDX2 1 dataset
ChIP COLO-320 GSE30026.CDX2.COLO-320 102 bp overlap
CTBP1 1 dataset
ChIP K-562 ENCSR201NQZ.CTBP1.K-562 224 bp overlap
CXXC5 1 dataset
ChIP K562 ENCFF497CZN 561 bp overlap
DPF2 1 dataset
ChIP K562 ENCFF775HUO 577 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 292 bp overlap
EP300 2 datasets
ChIP K-562 ENCSR000EGE.EP300.K-562 207 bp overlap
ChIP K562 ENCFF226VMS 317 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 730 bp overlap
ChIP DE DE-FOXA2-2 650 bp overlap
FOXO1-PAX3 1 dataset
ChIP RH4_DMSO-6H GSE116344.FOXO1-PAX3.RH4_DMSO-6H 183 bp overlap
GATA1 10 datasets
ChIP CD34_Day7_30min GSE104676.GATA1.CD34_Day7_30min 103 bp overlap
ChIP HUDEP-2_30min GSE104676.GATA1.HUDEP-2_30min 217 bp overlap
ChIP K-562 GSE107726.GATA1.K-562 406 bp overlap
ChIP K-562 ENCSR000EFT.GATA1.K-562 129 bp overlap
ChIP K-562_dCas9-LSD1 GSE132212.GATA1.K-562_dCas9-LSD1 267 bp overlap
ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 282 bp overlap
ChIP K562 ENCFF094CMK 251 bp overlap
ChIP erythroblast ENCSR000EXP.GATA1.erythroblast 353 bp overlap
ChIP erythroid_Don001 GSE137982.GATA1.erythroid_Don001 341 bp overlap
ChIP erythroid_Don003 GSE137982.GATA1.erythroid_Don003 228 bp overlap
GATA2 6 datasets
ChIP CD34_ACY957 GSE60792.GATA2.CD34_ACY957 141 bp overlap
Motif DE_60h DE_60h-GATA2_MA0036.4 7 bp overlap
ChIP K-562 ENCSR000BKM.GATA2.K-562 159 bp overlap
ChIP LNCaP_CSFCS GSE69043.GATA2.LNCaP_CSFCS 130 bp overlap
ChIP TF1 GSE73207.GATA2.TF1 381 bp overlap
ChIP primary-endometrial-stromal-cell_Veh_P2 GSE145673.GATA2.primary-endometrial-stromal-cell_Veh_P2 275 bp overlap
GATA3 1 dataset
ChIP MCF-7_E2 GSE60270.GATA3.MCF-7_E2 138 bp overlap
GATA4 9 datasets
ChIP DE DE-GATA4-1 764 bp overlap
ChIP DE DE-GATA4-2 701 bp overlap
Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap
ChIP Hep-G2 GSE135714.GATA4.Hep-G2 194 bp overlap
ChIP foregut GSE117136.GATA4.foregut 259 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 503 bp overlap
GATA5 4 datasets
Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
Motif DE_72h DE_72h-GATA5_MA0766.3 8 bp overlap
GATA6 15 datasets
ChIP DE DE-GATA6-1 771 bp overlap
ChIP DE DE-GATA6-2 778 bp overlap
Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 632 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 622 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 636 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 587 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 766 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 653 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 484 bp overlap
ChIP foregut GSE117136.GATA6.foregut 261 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 368 bp overlap
Gata3 4 datasets
Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap
HDAC1 2 datasets
ChIP K-562 ENCSR387UWP.HDAC1.K-562 333 bp overlap
ChIP K562 ENCFF968WBH 521 bp overlap
HDAC2 3 datasets
ChIP K-562 ENCSR893WSB.HDAC2.K-562 254 bp overlap
ChIP K-562 ENCSR075HTM.HDAC2.K-562 367 bp overlap
ChIP K562 ENCFF744ALD 421 bp overlap
HMBOX1 2 datasets
ChIP K-562 ENCSR757IIU.HMBOX1.K-562 381 bp overlap
ChIP K562 ENCFF055GAZ 531 bp overlap
HSF4 2 datasets
Motif DE_48h DE_48h-HSF4_MA0771.1 13 bp overlap
Motif DE_60h DE_60h-HSF4_MA0771.1 13 bp overlap
IKZF1 2 datasets
ChIP K-562 ENCSR395HWC.IKZF1.K-562 770 bp overlap
ChIP K562 ENCFF348IBL 398 bp overlap
ILF3 1 dataset
ChIP K-562 GSE103215.ILF3.K-562 789 bp overlap
JUND 1 dataset
ChIP K-562 ENCSR000EGN.JUND.K-562 111 bp overlap
KMT2A 2 datasets
ChIP HEK293T_N-term_C104 GSE90762.KMT2A.HEK293T_N-term_C104 463 bp overlap
ChIP HEK293T_N-term_C104 GSE90762.KMT2A.HEK293T_N-term_C104 57 bp overlap
LDB1 2 datasets
ChIP HEP GSE52637.LDB1.HEP 132 bp overlap
ChIP K-562 GSE142227.LDB1.K-562 222 bp overlap
MITF 4 datasets
ChIP 501-mel GSE137522.MITF.501-mel 267 bp overlap
ChIP 501-mel_20ng_K243R GSE137522.MITF.501-mel_20ng_K243R 287 bp overlap
ChIP K-562 ENCSR797SWM.MITF.K-562 327 bp overlap
ChIP K562 ENCFF731XJJ 188 bp overlap
MTA2 3 datasets
ChIP K-562 ENCSR411UYA.MTA2.K-562 233 bp overlap
ChIP RH4 GSE155861.MTA2.RH4 180 bp overlap
ChIP RH4 GSE155861.MTA2.RH4 166 bp overlap
MYB 1 dataset
ChIP DU528 GSE94000.MYB.DU528 248 bp overlap
Mecom 1 dataset
Motif DE_60h DE_60h-Mecom_MA0029.2 11 bp overlap
NEUROD1 2 datasets
ChIP D283-Med GSE92582.NEUROD1.D283-Med 381 bp overlap
ChIP D341-Med_shGFP GSE92582.NEUROD1.D341-Med_shGFP 155 bp overlap
NFE2 1 dataset
ChIP ProEs GSE59087.NFE2.ProEs 153 bp overlap
NKX6-3 3 datasets
Motif DE_48h DE_48h-NKX6-3_MA1530.2 8 bp overlap
Motif DE_60h DE_60h-NKX6-3_MA1530.2 8 bp overlap
Motif DE_72h DE_72h-NKX6-3_MA1530.2 8 bp overlap
NOTCH1 1 dataset
ChIP CD34 GSE63010.NOTCH1.CD34 223 bp overlap
OSR2 2 datasets
ChIP HEK293 ENCFF875BDB 335 bp overlap
ChIP HEK293 ENCSR324LTM.OSR2.HEK293 236 bp overlap
PHOX2B 3 datasets
Motif DE_48h DE_48h-PHOX2B_MA0681.3 12 bp overlap
Motif DE_60h DE_60h-PHOX2B_MA0681.3 12 bp overlap
Motif DE_72h DE_72h-PHOX2B_MA0681.3 12 bp overlap
PML 1 dataset
ChIP K-562 ENCSR000BQY.PML.K-562 221 bp overlap
POU2F1::SOX2 3 datasets
Motif DE_48h DE_48h-POU2F1SOX2_MA1962.1 17 bp overlap
Motif DE_60h DE_60h-POU2F1SOX2_MA1962.1 17 bp overlap
Motif DE_72h DE_72h-POU2F1SOX2_MA1962.1 17 bp overlap
PRDM10 1 dataset
ChIP HEK293 ENCFF145WQQ 145 bp overlap
PRDM6 2 datasets
ChIP HEK293 GSE76494.PRDM6.HEK293 296 bp overlap
ChIP HEK293 ENCSR892QHR.PRDM6.HEK293 382 bp overlap
PSIP1 2 datasets
ChIP T-REx-293 GSE117155.PSIP1.T-REx-293 72 bp overlap
ChIP T-REx-293 GSE117155.PSIP1.T-REx-293 179 bp overlap
Pou5f1::Sox2 3 datasets
Motif DE_48h DE_48h-Pou5f1Sox2_MA0142.1 15 bp overlap
Motif DE_60h DE_60h-Pou5f1Sox2_MA0142.1 15 bp overlap
Motif DE_72h DE_72h-Pou5f1Sox2_MA0142.1 15 bp overlap
RAD51 1 dataset
ChIP K562 ENCFF133ELP 314 bp overlap
RBPJ 3 datasets
Motif DE_48h DE_48h-RBPJ_MA1116.2 6 bp overlap
Motif DE_60h DE_60h-RBPJ_MA1116.2 6 bp overlap
Motif DE_72h DE_72h-RBPJ_MA1116.2 6 bp overlap
RCOR1 1 dataset
ChIP K562 ENCFF216EEJ 297 bp overlap
RNF2 1 dataset
ChIP K-562 ENCSR076YPO.RNF2.K-562 197 bp overlap
SETDB1 1 dataset
ChIP HEK293 ENCFF676PLV 91 bp overlap
SIX2 6 datasets
Motif DE_48h DE_48h-SIX2_MA1119.2 11 bp overlap
Motif DE_60h DE_60h-SIX2_MA1119.2 11 bp overlap
Motif DE_72h DE_72h-SIX2_MA1119.2 11 bp overlap
ChIP HEK GSE73865.SIX2.HEK 205 bp overlap
ChIP kidney_fetal_16w GSE75948.SIX2.kidney_fetal_16w 93 bp overlap
ChIP kidney_fetal_17w GSE75948.SIX2.kidney_fetal_17w 215 bp overlap
SMAD2 2 datasets
Motif DE_60h DE_60h-SMAD2_MA1964.2 6 bp overlap
ChIP endoderm GSE29422.SMAD2.endoderm 193 bp overlap
SMAD2-3 4 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 767 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 764 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 475 bp overlap
ChIP HUVEC-C_TGFB1 GSE134556.SMAD2-3.HUVEC-C_TGFB1 421 bp overlap
SMAD2_3 5 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 377 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 717 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 450 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 783 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 727 bp overlap
SMAD3 1 dataset
ChIP endoderm GSE29422.SMAD3.endoderm 195 bp overlap
SMAD4 1 dataset
ChIP endoderm GSE29422.SMAD4.endoderm 243 bp overlap
SMARCA4 3 datasets
ChIP K-562 ENCSR587OQL.SMARCA4.K-562 490 bp overlap
ChIP K562 ENCFF506JCB 517 bp overlap
ChIP hiPSC GSE124903.SMARCA4.hiPSC 202 bp overlap
SMARCC1 1 dataset
ChIP DE_D1 S15-DE-d1-BAF155-exp1 395 bp overlap
SMARCE1 2 datasets
ChIP K-562 ENCSR157TCS.SMARCE1.K-562 446 bp overlap
ChIP K562 ENCFF690CFF 517 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 624 bp overlap
SOX6 2 datasets
ChIP K-562 ENCSR788RSW.SOX6.K-562 283 bp overlap
ChIP K562 ENCFF059YCJ 437 bp overlap
SOX8 2 datasets
ChIP RH4 GSE116344.SOX8.RH4 210 bp overlap
ChIP RH4_DMSO-6H GSE116344.SOX8.RH4_DMSO-6H 214 bp overlap
SP7 2 datasets
ChIP HEK293 ENCFF733RBE 512 bp overlap
ChIP HEK293 ENCSR468IJT.SP7.HEK293 499 bp overlap
Stat4 3 datasets
Motif DE_48h DE_48h-Stat4_MA0518.2 10 bp overlap
Motif DE_60h DE_60h-Stat4_MA0518.2 10 bp overlap
Motif DE_72h DE_72h-Stat4_MA0518.2 10 bp overlap
TAL1 8 datasets
ChIP CD34 GSE52924.TAL1.CD34 134 bp overlap
ChIP HSPC-CD34pos GSE93372.TAL1.HSPC-CD34pos 127 bp overlap
ChIP K-562 GSE107726.TAL1.K-562 176 bp overlap
ChIP K-562 ENCSR000EHB.TAL1.K-562 118 bp overlap
ChIP K562 ENCFF620GMX 385 bp overlap
ChIP K562 ENCFF661CCK 277 bp overlap
ChIP ProEs GSE59087.TAL1.ProEs 216 bp overlap
ChIP TSU-1621MT GSE60477.TAL1.TSU-1621MT 200 bp overlap
TEAD4 1 dataset
ChIP K562 ENCFF673NIK 365 bp overlap
TFAP2B 2 datasets
Motif DE_48h DE_48h-TFAP2B_MA0811.2 11 bp overlap
Motif DE_60h DE_60h-TFAP2B_MA0811.2 11 bp overlap
TFAP2C 2 datasets
Motif DE_48h DE_48h-TFAP2C_MA0524.3 11 bp overlap
Motif DE_60h DE_60h-TFAP2C_MA0524.3 11 bp overlap
TFE3 1 dataset
ChIP K562 ENCFF697ABG 317 bp overlap
TP63 5 datasets
ChIP MCF-10A_Nutlin3A GSE111009.TP63.MCF-10A_Nutlin3A 203 bp overlap
ChIP SUIT-2 GSE115461.TP63.SUIT-2 270 bp overlap
ChIP keratinocyte_D0 GSE59824.TP63.keratinocyte_D0 251 bp overlap
ChIP keratinocyte_D2 GSE59824.TP63.keratinocyte_D2 181 bp overlap
ChIP keratinocyte_epidermal GSE67382.TP63.keratinocyte_epidermal 199 bp overlap
TP73_DELTANP 1 dataset
ChIP SaOS-2 GSE15780.TP73_DELTANP.SaOS-2 176 bp overlap
TRIM24 1 dataset
ChIP K-562 ENCSR907MZR.TRIM24.K-562 210 bp overlap
TRPS1 4 datasets
Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap
USF1 1 dataset
ChIP K-562 ENCSR000BKT.USF1.K-562 205 bp overlap
VEZF1 2 datasets
ChIP K562 ENCFF053XDV 671 bp overlap
ChIP K562 ENCFF053XDV 456 bp overlap
YY1 2 datasets
ChIP Hep-G2_NC GSE120104.YY1.Hep-G2_NC 438 bp overlap
ChIP RH4_DMSO-6H GSE116344.YY1.RH4_DMSO-6H 429 bp overlap
ZBTB7A 1 dataset
ChIP K-562 GSE103445.ZBTB7A.K-562 165 bp overlap
ZEB2 2 datasets
ChIP K-562 ENCSR322CFO.ZEB2.K-562 500 bp overlap
ChIP K-562 ENCSR004GKA.ZEB2.K-562 298 bp overlap
ZFP57 1 dataset
ChIP hESC GSE115387.ZFP57.hESC 171 bp overlap
ZIM3 1 dataset
ChIP HEK293 GSE76494.ZIM3.HEK293 226 bp overlap
ZNF121 2 datasets
ChIP HEK293 ENCFF839FUF 215 bp overlap
ChIP HEK293 ENCFF839FUF 415 bp overlap
ZNF2 1 dataset
ChIP HEK293 ENCSR011CKE.ZNF2.HEK293 225 bp overlap
ZNF24 1 dataset
Motif DE_60h DE_60h-ZNF24_MA1124.1 13 bp overlap
ZNF366 2 datasets
ChIP HEK293 ENCFF799ATK 263 bp overlap
ChIP HEK293 ENCSR106EBH.ZNF366.HEK293 153 bp overlap
ZNF449 2 datasets
ChIP HEK293 ENCFF764ZIC 374 bp overlap
ChIP HEK293 ENCSR738SLS.ZNF449.HEK293 381 bp overlap
ZNF549 2 datasets
Motif DE_48h DE_48h-ZNF549_MA1728.2 8 bp overlap
Motif DE_60h DE_60h-ZNF549_MA1728.2 8 bp overlap
ZNF660 1 dataset
ChIP HEK293 ENCSR283DOU.ZNF660.HEK293 133 bp overlap
ZNF75D 3 datasets
Motif DE_48h DE_48h-ZNF75D_MA1601.2 12 bp overlap
Motif DE_60h DE_60h-ZNF75D_MA1601.2 12 bp overlap
Motif DE_72h DE_72h-ZNF75D_MA1601.2 12 bp overlap
ZNF766 3 datasets
Motif DE_48h DE_48h-ZNF766_MA2098.1 9 bp overlap
Motif DE_60h DE_60h-ZNF766_MA2098.1 9 bp overlap
Motif DE_72h DE_72h-ZNF766_MA2098.1 9 bp overlap
Zic1::Zic2 1 dataset
Motif DE_60h DE_60h-Zic1Zic2_MA1628.2 7 bp overlap
Zic3 1 dataset
Motif DE_60h DE_60h-Zic3_MA0697.3 7 bp overlap
Znf423 1 dataset
Motif DE_60h DE_60h-Znf423_MA0116.1 15 bp overlap
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