chr4 : 4,857,851 – 4,858,461
610 bp 75 TFs 1 linked gene
This 610 bp open chromatin element is linked to MSX1 and is bound by 75 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
MSX1 1.2 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr4:4,852,851 – 4,863,461
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
75 transcription factors
Source
Cell type
AFF4 1 dataset
ChIP MCF-7 GSE144036.AFF4.MCF-7 403 bp overlap
AR 2 datasets
ChIP prostate_cancer-associated-fibroblasts GSE90772.AR.prostate_cancer-associated-fibroblasts 292 bp overlap
ChIP prostate_fetal-fibroblast GSE90772.AR.prostate_fetal-fibroblast 379 bp overlap
ASH2L 2 datasets
ChIP H1 ENCFF399KAM 610 bp overlap
ChIP WA01 ENCSR850KIP.ASH2L.WA01 255 bp overlap
Atoh1 1 dataset
Motif DE_24h DE_24h-Atoh1_MA1467.3 7 bp overlap
BRD1 2 datasets
ChIP HUES-64 GSE104059.BRD1.HUES-64 271 bp overlap
ChIP HUES-64 GSE104059.BRD1.HUES-64 233 bp overlap
BRD4 6 datasets
ChIP CLL_patient2 GSE109411.BRD4.CLL_patient2 519 bp overlap
ChIP CLL_patient2_4h_CpG_BET GSE109411.BRD4.CLL_patient2_4h_CpG_BET 407 bp overlap
ChIP COLO-741 GSE73319.BRD4.COLO-741 251 bp overlap
ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 430 bp overlap
ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 205 bp overlap
ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 278 bp overlap
CBX7 1 dataset
ChIP HEK293T_PCGF2fl GSE119618.CBX7.HEK293T_PCGF2fl 306 bp overlap
CBX8 1 dataset
ChIP H1 ENCFF095JHA 65 bp overlap
CDK9 1 dataset
ChIP HCT-116 GSE72622.CDK9.HCT-116 207 bp overlap
CDKN1B 1 dataset
ChIP MDA-MB-231_p27CK-DD GSE112444.CDKN1B.MDA-MB-231_p27CK-DD 218 bp overlap
CDX2 1 dataset
ChIP intestinal-cell GSE115314.CDX2.intestinal-cell 309 bp overlap
CTBP2 1 dataset
ChIP WA01 ENCSR000EUO.CTBP2.WA01 158 bp overlap
CTCF 5 datasets
ChIP Kelly_sensitive GSE103030.CTCF.Kelly_sensitive 111 bp overlap
ChIP WA01_NEUR GSE52457.CTCF.WA01_NEUR 139 bp overlap
ChIP hESC_D5 GSE116862.CTCF.hESC_D5 244 bp overlap
ChIP neuron_bipolar_doxy_4d ENCSR619IUE.CTCF.neuron_bipolar_doxy_4d 122 bp overlap
ChIP type B pancreatic cell ENCFF910FNQ 491 bp overlap
CTNNB1 2 datasets
ChIP hiPSC_D2 GSE132532.CTNNB1.hiPSC_D2 185 bp overlap
ChIP hiPSC_TT-neg_D2 GSE132532.CTNNB1.hiPSC_TT-neg_D2 208 bp overlap
Cebpa 2 datasets
ChIP BLaER1 ENCFF031ISE 251 bp overlap
ChIP BLaER1 ENCFF274GAT 264 bp overlap
ELF1 1 dataset
ChIP GM12878 ENCSR000BMB.ELF1.GM12878 276 bp overlap
ETS1 2 datasets
ChIP HUVEC-C_VEGF_12H GSE41166.ETS1.HUVEC-C_VEGF_12H 211 bp overlap
ChIP cardiomyocyte_D0 GSE129986.ETS1.cardiomyocyte_D0 225 bp overlap
ETV5::DRGX 1 dataset
Motif DE_24h DE_24h-ETV5DRGX_MA1944.2 12 bp overlap
EZH2 23 datasets
ChIP B-cell ENCSR000AUZ.EZH2.B-cell 414 bp overlap
ChIP GM23338 ENCFF613YON 610 bp overlap
ChIP GM23338 ENCFF886DXX 472 bp overlap
ChIP H1 ENCFF232NZA 610 bp overlap
ChIP HUVEC-C_VEGF_12h GSE109625.EZH2.HUVEC-C_VEGF_12h 610 bp overlap
ChIP HUVEC-C_VEGF_4h GSE109625.EZH2.HUVEC-C_VEGF_4h 610 bp overlap
ChIP LNCaP-abl GSE39459.EZH2.LNCaP-abl 494 bp overlap
ChIP SK-N-SH ENCFF657FZK 220 bp overlap
ChIP astrocyte ENCFF365JTP 595 bp overlap
ChIP astrocyte ENCFF365JTP 200 bp overlap
ChIP astrocyte ENCFF365JTP 334 bp overlap
ChIP endothelial cell of umbilical vein ENCFF539AKL 610 bp overlap
ChIP epithelial_mammary ENCSR000ARE.EZH2.epithelial_mammary 217 bp overlap
ChIP fibroblast of lung ENCFF479BAW 141 bp overlap
ChIP fibroblast of lung ENCFF479BAW 350 bp overlap
ChIP fibroblast_LUNG ENCSR000ARO.EZH2.fibroblast_LUNG 117 bp overlap
ChIP fibroblast_LUNG ENCSR000ARO.EZH2.fibroblast_LUNG 272 bp overlap
ChIP hepatocyte ENCFF552DZB 610 bp overlap
ChIP keratinocyte ENCFF070STK 231 bp overlap
ChIP keratinocyte ENCFF070STK 525 bp overlap
ChIP neural cell ENCFF610EPB 401 bp overlap
ChIP neural progenitor cell ENCFF018MKA 610 bp overlap
ChIP neural progenitor cell ENCFF472NFV 610 bp overlap
EZH2_phosphoT487 1 dataset
ChIP OCI-Ly7 ENCSR565XSL.EZH2_phosphoT487.OCI-Ly7 101 bp overlap
FOXP1 1 dataset
ChIP H9 GSE31006.FOXP1.H9 170 bp overlap
GATA2 1 dataset
ChIP hiPSC_SLC6ebs GSE107639.GATA2.hiPSC_SLC6ebs 345 bp overlap
GATA6 5 datasets
ChIP DE_D1 S09-DE-d1-GATA6-exp1 509 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 600 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 538 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 588 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 610 bp overlap
HAND2 1 dataset
Motif DE_24h DE_24h-HAND2_MA1638.2 6 bp overlap
HEXIM1 2 datasets
ChIP HCT-116 GSE72622.HEXIM1.HCT-116 254 bp overlap
ChIP HCT-116 GSE72622.HEXIM1.HCT-116 133 bp overlap
HIF1A 1 dataset
ChIP BEAS-2B_arsenic GSE145834.HIF1A.BEAS-2B_arsenic 254 bp overlap
HOXB13 1 dataset
ChIP G-401 GSE65381.HOXB13.G-401 467 bp overlap
HOXB2::ELK1 1 dataset
Motif DE_24h DE_24h-HOXB2ELK1_MA1957.1 14 bp overlap
IKZF1 1 dataset
ChIP pre-B-cell GSE107886.IKZF1.pre-B-cell 323 bp overlap
JARID2 3 datasets
ChIP AMIPS6 GSE48516.JARID2.AMIPS6 610 bp overlap
ChIP AMIPS8 GSE48516.JARID2.AMIPS8 610 bp overlap
ChIP UTEIPS4 GSE48516.JARID2.UTEIPS4 610 bp overlap
JUN 4 datasets
ChIP DE_D1 S08-DE-d1-JUN-exp1 235 bp overlap
ChIP DE_D1 S40-DE-d1-JUN-exp2 282 bp overlap
ChIP HUES-8 GSE109524.JUN.HUES-8 287 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 456 bp overlap
LDB1 1 dataset
ChIP H9_DOX-0 GSE137670.LDB1.H9_DOX-0 132 bp overlap
LMO2 1 dataset
ChIP CCRF-CEM GSE33850.LMO2.CCRF-CEM 174 bp overlap
MAFF 1 dataset
Motif DE_24h DE_24h-MAFF_MA0495.4 11 bp overlap
MTF2 2 datasets
ChIP DU145_SH4 GSE135623.MTF2.DU145_SH4 455 bp overlap
ChIP DU145_SH4 GSE135623.MTF2.DU145_SH4 87 bp overlap
MYCN 1 dataset
ChIP COG-N-415 GSE138295.MYCN.COG-N-415 232 bp overlap
Mafb 1 dataset
Motif DE_24h DE_24h-Mafb_MA0117.3 11 bp overlap
Msgn1 1 dataset
Motif DE_24h DE_24h-Msgn1_MA1524.3 10 bp overlap
NANOG 3 datasets
ChIP HUES-8 GSE109524.NANOG.HUES-8 426 bp overlap
ChIP WA01 ENCSR000BMT.NANOG.WA01 204 bp overlap
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 163 bp overlap
NEUROD1 1 dataset
Motif DE_24h DE_24h-NEUROD1_MA1109.2 8 bp overlap
NEUROG2 1 dataset
Motif DE_24h DE_24h-NEUROG2_MA1642.2 7 bp overlap
NFYA 1 dataset
Motif DE_24h DE_24h-NFYA_MA0060.4 8 bp overlap
NFYC 1 dataset
Motif DE_24h DE_24h-NFYC_MA1644.2 7 bp overlap
NRL 1 dataset
Motif DE_24h DE_24h-NRL_MA0842.3 12 bp overlap
Neurod2 1 dataset
Motif DE_24h DE_24h-Neurod2_MA0668.3 8 bp overlap
PHIP 1 dataset
ChIP HCT-116_MLL1-KO__ab833 GSE101646.PHIP.HCT-116_MLL1-KO__ab833 420 bp overlap
POU5F1 4 datasets
ChIP DE_D1 DED1-OCT4_Batch_II 577 bp overlap
ChIP HUES-8 GSE109524.POU5F1.HUES-8 287 bp overlap
ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 350 bp overlap
ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 165 bp overlap
PRPF4 2 datasets
ChIP Hep-G2 GSE120104.PRPF4.Hep-G2 145 bp overlap
ChIP Hep-G2 ENCSR243LNQ.PRPF4.Hep-G2 140 bp overlap
Ptf1A 1 dataset
Motif DE_24h DE_24h-Ptf1A_MA1618.2 9 bp overlap
RARA 2 datasets
ChIP hiPSC_D3 GSE109172.RARA.hiPSC_D3 340 bp overlap
ChIP hiPSC_D4 GSE109172.RARA.hiPSC_D4 421 bp overlap
RARA::RXRA 1 dataset
Motif DE_24h DE_24h-RARARXRA_MA0159.1 17 bp overlap
RELA 1 dataset
ChIP HEK293_TNF-1h GSE75562.RELA.HEK293_TNF-1h 404 bp overlap
RNF2 3 datasets
ChIP H1 ENCFF239FFS 610 bp overlap
ChIP H1 ENCFF239FFS 610 bp overlap
ChIP HEK293T_PCGF2fl GSE119618.RNF2.HEK293T_PCGF2fl 259 bp overlap
SALL3 1 dataset
ChIP hiPSC GSE104863.SALL3.hiPSC 192 bp overlap
SMAD2-3 2 datasets
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 610 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 610 bp overlap
SMAD2_3 3 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 518 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 569 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 565 bp overlap
SMARCA4 2 datasets
ChIP CTV-1_DSG GSE128835.SMARCA4.CTV-1_DSG 126 bp overlap
ChIP HS-SY-2_HA-tagged GSE108926.SMARCA4.HS-SY-2_HA-tagged 294 bp overlap
SMARCC1 1 dataset
ChIP Aska-SS GSE108025.SMARCC1.Aska-SS 275 bp overlap
SP5 1 dataset
Motif DE_24h DE_24h-SP5_MA1965.2 6 bp overlap
SPI1 1 dataset
ChIP CTV-1_FLAG_15perc GSE128835.SPI1.CTV-1_FLAG_15perc 51 bp overlap
SRSF1 1 dataset
ChIP Hep-G2 GSE120104.SRSF1.Hep-G2 221 bp overlap
SRSF3 1 dataset
ChIP K-562 GSE120104.SRSF3.K-562 246 bp overlap
SS18 1 dataset
ChIP Aska-SS GSE108025.SS18.Aska-SS 562 bp overlap
SUZ12 12 datasets
ChIP Aska-SS GSE108025.SUZ12.Aska-SS 504 bp overlap
ChIP CRL-7250_shSS18 GSE108025.SUZ12.CRL-7250_shSS18 610 bp overlap
ChIP GM12878 ENCSR091BOQ.SUZ12.GM12878 480 bp overlap
ChIP H1 ENCFF507HGF 97 bp overlap
ChIP H1 ENCFF881NFR 610 bp overlap
ChIP HEK293T_PCGF135fl GSE119618.SUZ12.HEK293T_PCGF135fl 309 bp overlap
ChIP HEK293T_PCGF2fl GSE119618.SUZ12.HEK293T_PCGF2fl 447 bp overlap
ChIP NT2-D1 GSE101538.SUZ12.NT2-D1 487 bp overlap
ChIP ProEs GSE59087.SUZ12.ProEs 169 bp overlap
ChIP WA01 ENCSR000EUQ.SUZ12.WA01 52 bp overlap
ChIP WA01 ENCSR000ATS.SUZ12.WA01 610 bp overlap
ChIP WA01 ENCSR000EUQ.SUZ12.WA01 335 bp overlap
TAL1 1 dataset
ChIP CHRF28811 ERP008568.TAL1.CHRF28811 316 bp overlap
TCF12 1 dataset
ChIP WA01 ENCSR000BIT.TCF12.WA01 229 bp overlap
YY1 1 dataset
ChIP WA01 ENCSR000BKD.YY1.WA01 199 bp overlap
ZBTB33 1 dataset
ChIP K-562 ENCSR876GXA.ZBTB33.K-562 433 bp overlap
ZBTB48 2 datasets
ChIP U2OS GSE96776.ZBTB48.U2OS 358 bp overlap
ChIP U2OS_ZBTB48-KO GSE96776.ZBTB48.U2OS_ZBTB48-KO 545 bp overlap
ZFX 1 dataset
ChIP HEK293T_FLAG GSE145160.ZFX.HEK293T_FLAG 260 bp overlap
ZKSCAN5 1 dataset
Motif DE_24h DE_24h-ZKSCAN5_MA1652.2 9 bp overlap
ZNF354C 1 dataset
ChIP K562 ENCFF371JMA 285 bp overlap
ZNF512 2 datasets
ChIP K-562 ENCSR591CCL.ZNF512.K-562 144 bp overlap
ChIP WTC11 ENCFF086TTM 217 bp overlap
ZNF513 2 datasets
ChIP HEK293 ENCFF457TCC 88 bp overlap
ChIP HEK293 ENCSR503DPC.ZNF513.HEK293 96 bp overlap
Zbtb2 1 dataset
Motif DE_24h DE_24h-Zbtb2_MA2340.1 10 bp overlap
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