chr2 : 207,093,267 – 207,093,735

468 bp 65 TFs 3 linked genes

This 468 bp open chromatin element is linked to KLF7, CPO, and ENSG00000229321 and is bound by 65 transcription factors.

Linked Genes

3 genes

Gene	Dist. to TSS	Distance	Link type
KLF7	73.6 kb	Distal	Multiome
CPO	153.8 kb	Distal	Multiome
ENSG00000229321	294.9 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

65 transcription factors

AR 1 dataset

ChIP VCaP GSE148358.AR.VCaP 83 bp overlap

ARID1A 1 dataset

ChIP HAP1 GSE108387.ARID1A.HAP1 250 bp overlap

ASH2L 2 datasets

ChIP H1 ENCFF399KAM 468 bp overlap

ChIP WA01 ENCSR850KIP.ASH2L.WA01 414 bp overlap

ATF2 1 dataset

ChIP WA01 ENCSR000BQU.ATF2.WA01 233 bp overlap

BCOR 1 dataset

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 163 bp overlap

BRD3 1 dataset

ChIP HUVEC-C GSE60171.BRD3.HUVEC-C 225 bp overlap

BRD4 3 datasets

ChIP HAP1 GSE108387.BRD4.HAP1 468 bp overlap

ChIP SK-N-BE2-C_Resistant-veh GSE107706.BRD4.SK-N-BE2-C_Resistant-veh 468 bp overlap

ChIP hESC GSE33281.BRD4.hESC 87 bp overlap

BRF1 1 dataset

ChIP H9 GSE94418.BRF1.H9 155 bp overlap

CEBPB 1 dataset

ChIP HFOB_DIFF GSE82295.CEBPB.HFOB_DIFF 87 bp overlap

CHD1 1 dataset

ChIP WA01 ENCSR000AQK.CHD1.WA01 164 bp overlap

CHD7 1 dataset

ChIP WA01 ENCSR000AVA.CHD7.WA01 149 bp overlap

CTCF 1 dataset

ChIP HAP1_clone21_CTCF-TSS-CRISPR_1 GSE152721.CTCF.HAP1_clone21_CTCF-TSS-CRISPR_1 295 bp overlap

E2F6 2 datasets

ChIP H1 ENCFF785DWK 369 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 151 bp overlap

ESR1 1 dataset

ChIP MCF-7 GSE148277.ESR1.MCF-7 97 bp overlap

EWSR1-FLI1 1 dataset

Motif DE_12h DE_12h-EWSR1-FLI1_MA0149.1 18 bp overlap

FOXO1 1 dataset

ChIP CD34 GSE80773.FOXO1.CD34 233 bp overlap

GABPA 1 dataset

ChIP VCaP_R1881 GSE49091.GABPA.VCaP_R1881 102 bp overlap

GTF3C2 1 dataset

ChIP H9 GSE94418.GTF3C2.H9 204 bp overlap

HNF4A 2 datasets

Motif DE_12h DE_12h-HNF4A_MA1494.2 14 bp overlap

Motif ES_0h ES_0h-HNF4A_MA1494.2 14 bp overlap

KDM1A 1 dataset

ChIP H1 ENCFF696SGD 468 bp overlap

KLF10 1 dataset

Motif DE_12h DE_12h-KLF10_MA1511.2 9 bp overlap

KLF12 1 dataset

Motif DE_12h DE_12h-KLF12_MA0742.2 9 bp overlap

KLF14 1 dataset

Motif DE_12h DE_12h-KLF14_MA0740.2 9 bp overlap

KLF17 1 dataset

Motif DE_12h DE_12h-KLF17_MA1514.2 14 bp overlap

KLF5 1 dataset

Motif DE_12h DE_12h-KLF5_MA0599.1 10 bp overlap

MAX 1 dataset

ChIP H1 ENCFF914VQY 105 bp overlap

MAZ 1 dataset

Motif DE_12h DE_12h-MAZ_MA1522.2 8 bp overlap

NANOG 4 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 403 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 448 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 308 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 210 bp overlap

NR3C1 1 dataset

ChIP BEAS-2B_DEX_IA1 GSE125623.NR3C1.BEAS-2B_DEX_IA1 96 bp overlap

PATZ1 1 dataset

Motif DE_12h DE_12h-PATZ1_MA1961.2 11 bp overlap

POU5F1 7 datasets

ChIP BG03 GSE21614.POU5F1.BG03 165 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 355 bp overlap

ChIP NCCIT GSE36134.POU5F1.NCCIT 166 bp overlap

ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 468 bp overlap

ChIP WA09_heat-shock GSE105028.POU5F1.WA09_heat-shock 269 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 313 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 64 bp overlap

RAD21 4 datasets

ChIP HAP1 GSE126634.RAD21.HAP1 435 bp overlap

ChIP HAP1 GSE152721.RAD21.HAP1 319 bp overlap

ChIP HAP1_CTCF GSE126634.RAD21.HAP1_CTCF 359 bp overlap

ChIP WA09_heat-shock GSE105028.RAD21.WA09_heat-shock 184 bp overlap

RELA 1 dataset

ChIP MCF-7_IL1b_45m GSE67295.RELA.MCF-7_IL1b_45m 144 bp overlap

SMARCA4 2 datasets

ChIP hiPSC GSE124903.SMARCA4.hiPSC 72 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 449 bp overlap

SMARCB1 1 dataset

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 382 bp overlap

SMARCC1 3 datasets

ChIP ESC S25-ESC-d0-BAF155-exp1 161 bp overlap

ChIP hiPSC GSE124903.SMARCC1.hiPSC 177 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 86 bp overlap

SOX2 1 dataset

ChIP hiPSC GSE56567.SOX2.hiPSC 72 bp overlap

SP1 1 dataset

Motif DE_12h DE_12h-SP1_MA0079.5 9 bp overlap

SP2 1 dataset

Motif DE_12h DE_12h-SP2_MA0516.3 9 bp overlap

SP4 1 dataset

Motif DE_12h DE_12h-SP4_MA0685.2 9 bp overlap

SP5 1 dataset

Motif DE_12h DE_12h-SP5_MA1965.2 6 bp overlap

STAT3 2 datasets

Motif DE_12h DE_12h-STAT3_MA0144.3 9 bp overlap

Motif ES_0h ES_0h-STAT3_MA0144.3 9 bp overlap

Spi1 1 dataset

Motif DE_12h DE_12h-Spi1_MA0080.7 13 bp overlap

TBP 2 datasets

ChIP H1 ENCFF859IIO 322 bp overlap

ChIP WA01 ENCSR000ECB.TBP.WA01 162 bp overlap

TBX18 1 dataset

Motif DE_12h DE_12h-TBX18_MA1565.2 9 bp overlap

TBX5 2 datasets

ChIP cardiomyocyte GSE85628.TBX5.cardiomyocyte 327 bp overlap

ChIP cardiomyocyte_1 GSE85628.TBX5.cardiomyocyte_1 327 bp overlap

TEAD4 2 datasets

ChIP H1 ENCFF778PAX 245 bp overlap

ChIP hMSC-TERT4 GSE140782.TEAD4.hMSC-TERT4 245 bp overlap

TFAP2A 1 dataset

Motif DE_12h DE_12h-TFAP2A_MA0810.2 11 bp overlap

TFAP2B 1 dataset

Motif DE_12h DE_12h-TFAP2B_MA0811.2 11 bp overlap

TFAP2C 2 datasets

Motif DE_12h DE_12h-TFAP2C_MA0524.3 11 bp overlap

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 336 bp overlap

THAP1 1 dataset

Motif DE_12h DE_12h-THAP1_MA0597.3 8 bp overlap

TP53 1 dataset

ChIP hESC_DAMAGED GSE39912.TP53.hESC_DAMAGED 166 bp overlap

TRIM28 4 datasets

ChIP HEK293 ENCFF582MWI 455 bp overlap

ChIP HEK293 ENCFF582MWI 244 bp overlap

ChIP WIBR3_NAIVE GSE84382.TRIM28.WIBR3_NAIVE 256 bp overlap

ChIP hESC GSE115387.TRIM28.hESC 175 bp overlap

ZBTB12 2 datasets

Motif DE_12h DE_12h-ZBTB12_MA1649.2 7 bp overlap

Motif ES_0h ES_0h-ZBTB12_MA1649.2 7 bp overlap

ZBTB7A 1 dataset

ChIP VCaP_FBS GSE123089.ZBTB7A.VCaP_FBS 233 bp overlap

ZKSCAN5 1 dataset

Motif DE_12h DE_12h-ZKSCAN5_MA1652.2 9 bp overlap

ZNF148 1 dataset

Motif DE_12h DE_12h-ZNF148_MA1653.2 10 bp overlap

ZNF16 2 datasets

Motif DE_12h DE_12h-ZNF16_MA1654.2 21 bp overlap

Motif ES_0h ES_0h-ZNF16_MA1654.2 21 bp overlap

ZNF257 2 datasets

Motif DE_12h DE_12h-ZNF257_MA1710.2 10 bp overlap

Motif ES_0h ES_0h-ZNF257_MA1710.2 10 bp overlap

ZNF281 1 dataset

Motif DE_12h DE_12h-ZNF281_MA1630.3 10 bp overlap

ZNF343 1 dataset

Motif DE_12h DE_12h-ZNF343_MA1711.2 16 bp overlap

ZNF462 1 dataset

ChIP GM23338 ENCFF896CCA 251 bp overlap

ZNF549 1 dataset

Motif DE_12h DE_12h-ZNF549_MA1728.2 8 bp overlap

ZSCAN31 1 dataset

Motif DE_12h DE_12h-ZSCAN31_MA1722.2 18 bp overlap

Zfp335 2 datasets

Motif DE_12h DE_12h-Zfp335_MA2002.2 7 bp overlap