chr22:43,226,308–43,226,848

chr22 : 43,226,308 – 43,226,848

540 bp 56 TFs 7 linked genes

This 540 bp open chromatin element is linked to 7 target genes and is bound by 56 transcription factors.

Linked Genes

7 genes

Gene	Expression	Dist. to TSS	Distance	Link type
TTLL12		39.4 kb	Distal	Multiome
TSPO		75.0 kb	Distal	Multiome
MCAT		83.2 kb	Distal	Multiome
SCUBE1		116.8 kb	Distal	Multiome
TTLL1		137.2 kb	Distal	Multiome
PACSIN2		211.4 kb	Distal	Multiome
EFCAB6		585.6 kb	Distal	Multiome+HiCAR

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

56 transcription factors

ChIP Hep-G2 ENCSR555ZMV.AGO1.Hep-G2 183 bp overlap

ChIP MDA-MB-453_FOXA1 ERP003503.AR.MDA-MB-453_FOXA1 152 bp overlap

ChIP VCaP_DHT24H_SHFOXP1 GSE58428.AR.VCaP_DHT24H_SHFOXP1 162 bp overlap

ChIP VCaP_DHT24H_SHRUNX1 GSE58428.AR.VCaP_DHT24H_SHRUNX1 57 bp overlap

ChIP prostate_1798_T GSE130408.AR.prostate_1798_T 81 bp overlap

ChIP prostate_1816_T GSE130408.AR.prostate_1816_T 313 bp overlap

ASH2L 1 dataset

ChIP WA01 ENCSR850KIP.ASH2L.WA01 238 bp overlap

BCOR 2 datasets

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 448 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 540 bp overlap

BRD4 4 datasets

ChIP Kelly_sensitive GSE103030.BRD4.Kelly_sensitive 444 bp overlap

ChIP VCaP_R1881 GSE148358.BRD4.VCaP_R1881 219 bp overlap

ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 268 bp overlap

ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 133 bp overlap

CTCF 98 datasets

ChIP 786-O_NORMOXIA GSE78113.CTCF.786-O_NORMOXIA 265 bp overlap

ChIP AG04449 ENCFF248MBD 181 bp overlap

ChIP AG04450 ENCFF116DJL 297 bp overlap

ChIP AG09309 ENCFF478XPS 277 bp overlap

ChIP AG09319 ENCFF401ZTN 277 bp overlap

ChIP AG10803 ENCFF549AQK 257 bp overlap

ChIP BE2C ENCFF757SRF 317 bp overlap

ChIP BE2C ENCSR000DQD.CTCF.BE2C 215 bp overlap

ChIP BJ ENCFF434HEC 311 bp overlap

ChIP BJ ENCSR000DQI.CTCF.BJ 245 bp overlap

ChIP H1 ENCFF230QSV 165 bp overlap

ChIP H1 ENCFF414GZI 217 bp overlap

ChIP H1 ENCFF764RHO 277 bp overlap

ChIP H9 ENCFF152GTF 215 bp overlap

ChIP Hep-G2 ERP000209.CTCF.Hep-G2 147 bp overlap

ChIP Hep-G2 ENCSR000BIE.CTCF.Hep-G2 144 bp overlap

ChIP Hep-G2 ENCSR000DLS.CTCF.Hep-G2 99 bp overlap

ChIP Hep-G2 ENCSR000DUG.CTCF.Hep-G2 134 bp overlap

ChIP HepG2 ENCFF127KUP 231 bp overlap

ChIP HepG2 ENCFF757EKU 351 bp overlap

ChIP IMR-90 ENCSR000EFI.CTCF.IMR-90 158 bp overlap

ChIP IMR-90 GSE43070.CTCF.IMR-90 141 bp overlap

ChIP K-562 GSE70764.CTCF.K-562 169 bp overlap

ChIP K562 ENCFF111MGE 245 bp overlap

ChIP Kelly_resistant GSE103030.CTCF.Kelly_resistant 156 bp overlap

ChIP Kelly_sensitive GSE103030.CTCF.Kelly_sensitive 219 bp overlap

ChIP MCF-7 ENCFF198DQX 231 bp overlap

ChIP MCF-7 ENCFF414SZG 191 bp overlap

ChIP MCF-7 ENCFF424NQR 191 bp overlap

ChIP MCF-7 ENCFF494VXA 231 bp overlap

ChIP MCF-7 ENCSR000DMR.CTCF.MCF-7 152 bp overlap

ChIP MCF-7 ERP000380.CTCF.MCF-7 137 bp overlap

ChIP MCF-7_E2 ERP000380.CTCF.MCF-7_E2 143 bp overlap

ChIP MCF-7_TAM ERP000380.CTCF.MCF-7_TAM 173 bp overlap

ChIP MCF-7_TAM ERP000783.CTCF.MCF-7_TAM 103 bp overlap

ChIP NB69 GSE101295.CTCF.NB69 193 bp overlap

ChIP RH4 GSE83726.CTCF.RH4 151 bp overlap

ChIP SK-N-AS GSE101295.CTCF.SK-N-AS 121 bp overlap

ChIP T-47D_Y537S GSE148277.CTCF.T-47D_Y537S 235 bp overlap

ChIP WA01 ENCSR000BNH.CTCF.WA01 158 bp overlap

ChIP WA01 ENCSR000DLK.CTCF.WA01 131 bp overlap

ChIP WA01_NEUR GSE52457.CTCF.WA01_NEUR 144 bp overlap

ChIP WERI-Rb-1 ENCFF349QKF 231 bp overlap

ChIP WERI-Rb-1 ENCSR000DXW.CTCF.WERI-Rb-1 143 bp overlap

ChIP adrenal-gland ENCSR770IWO.CTCF.adrenal-gland 153 bp overlap

ChIP astrocyte_cerebellum ENCSR000DSZ.CTCF.astrocyte_cerebellum 212 bp overlap

ChIP bonchial_epithelial ENCSR000DXI.CTCF.bonchial_epithelial 110 bp overlap

ChIP brain ENCFF067KUH 415 bp overlap

ChIP brain ENCFF163BBN 185 bp overlap

ChIP brain ENCFF685VRG 482 bp overlap

ChIP brain microvascular endothelial cell ENCFF526VHE 281 bp overlap

ChIP cardiac muscle cell ENCFF777TNC 365 bp overlap

ChIP cardiac-muscle ENCSR713SXF.CTCF.cardiac-muscle 262 bp overlap

ChIP cardiac_muscle ENCSR000DTI.CTCF.cardiac_muscle 231 bp overlap

ChIP chondrocyte ENCFF134ORZ 229 bp overlap

ChIP endodermal cell ENCFF471YCZ 231 bp overlap

ChIP endodermal cell ENCFF471YCZ 314 bp overlap

ChIP endothelial_brain-microvascular ENCSR000DTA.CTCF.endothelial_brain-microvascular 237 bp overlap

ChIP epithelial_mammary ENCSR000DUS.CTCF.epithelial_mammary 131 bp overlap

ChIP epithelial_retinal_pigment ENCSR000DVI.CTCF.epithelial_retinal_pigment 168 bp overlap

ChIP erythroid GSE67783.CTCF.erythroid 205 bp overlap

ChIP fibroblast of lung ENCFF356FDN 317 bp overlap

ChIP fibroblast of villous mesenchyme ENCFF345VQO 321 bp overlap

ChIP fibroblast_FORESKIN ENCSR000DWQ.CTCF.fibroblast_FORESKIN 219 bp overlap

ChIP fibroblast_GINGIVA ENCSR000DPS.CTCF.fibroblast_GINGIVA 206 bp overlap

ChIP fibroblast_LUNG ENCSR000DPM.CTCF.fibroblast_LUNG 167 bp overlap

ChIP fibroblast_LUNG ENCSR000DVA.CTCF.fibroblast_LUNG 126 bp overlap

ChIP fibroblast_SKIN_ABDOMEN ENCSR000DPV.CTCF.fibroblast_SKIN_ABDOMEN 131 bp overlap

ChIP fibroblast_SKIN_LEG ENCSR000DPG.CTCF.fibroblast_SKIN_LEG 182 bp overlap

ChIP fibroblast_VILLOUS_MESENCHYME ENCSR000DVQ.CTCF.fibroblast_VILLOUS_MESENCHYME 209 bp overlap

ChIP foreskin fibroblast ENCFF671HLG 321 bp overlap

ChIP hESC_D0 GSE116862.CTCF.hESC_D0 187 bp overlap

ChIP hESC_D5 GSE116862.CTCF.hESC_D5 540 bp overlap

ChIP hepatocyte ENCFF263BLJ 345 bp overlap

ChIP hepatocyte ENCSR252QYR.CTCF.hepatocyte 290 bp overlap

ChIP keratinocyte ENCSR000DWX.CTCF.keratinocyte 159 bp overlap

ChIP keratinocyte GSE154221.CTCF.keratinocyte 168 bp overlap

ChIP leukemia GSE142161.CTCF.leukemia 191 bp overlap

ChIP mammary epithelial cell ENCFF164SPU 265 bp overlap

ChIP myoblast_skeletal_muscle ENCSR000ANE.CTCF.myoblast_skeletal_muscle 192 bp overlap

ChIP myotube ENCSR000ANS.CTCF.myotube 251 bp overlap

ChIP nephron ENCFF411ACD 450 bp overlap

ChIP nephron ENCFF972IQB 354 bp overlap

ChIP neural crest cell ENCFF182LWK 427 bp overlap

ChIP neural progenitor cell ENCFF420RBO 132 bp overlap

ChIP neural progenitor cell ENCFF581WPG 475 bp overlap

ChIP neural progenitor cell ENCFF581WPG 433 bp overlap

ChIP neural_progenitor ENCSR125NBL.CTCF.neural_progenitor 354 bp overlap

ChIP neuron_bipolar_doxy_4d ENCSR619IUE.CTCF.neuron_bipolar_doxy_4d 178 bp overlap

ChIP osteocyte ENCFF929FPD 453 bp overlap

ChIP primary-glioblastoma_G523 GSE121601.CTCF.primary-glioblastoma_G523 231 bp overlap

ChIP primary-glioblastoma_G567 GSE121601.CTCF.primary-glioblastoma_G567 218 bp overlap

ChIP primary-glioblastoma_G583 GSE121601.CTCF.primary-glioblastoma_G583 224 bp overlap

ChIP prostate_epithelial ENCSR196HOM.CTCF.prostate_epithelial 354 bp overlap

ChIP retinal pigment epithelial cell ENCFF810AAG 257 bp overlap

ChIP skeletal muscle myoblast ENCFF813BQI 291 bp overlap

ChIP smooth-muscle-cell ENCSR261VAS.CTCF.smooth-muscle-cell 270 bp overlap

ChIP type B pancreatic cell ENCFF910FNQ 228 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF896HSY 149 bp overlap

E2F6 2 datasets

ChIP H1 ENCFF785DWK 406 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 177 bp overlap

ESR1 9 datasets

ChIP MCF-7 GSE119057.ESR1.MCF-7 289 bp overlap

ChIP MCF-7_ER_t10 GSE119057.ESR1.MCF-7_ER_t10 237 bp overlap

ChIP MCF-7_ER_t20 GSE119057.ESR1.MCF-7_ER_t20 198 bp overlap

ChIP MCF-7_ER_t30 GSE119057.ESR1.MCF-7_ER_t30 227 bp overlap

ChIP MCF-7_ER_t40 GSE119057.ESR1.MCF-7_ER_t40 213 bp overlap

ChIP MCF-7_ER_t50 GSE119057.ESR1.MCF-7_ER_t50 231 bp overlap

ChIP MCF-7_ER_t70 GSE119057.ESR1.MCF-7_ER_t70 203 bp overlap

ChIP MCF-7_ER_t80 GSE119057.ESR1.MCF-7_ER_t80 218 bp overlap

ChIP MCF-7_ER_t90 GSE119057.ESR1.MCF-7_ER_t90 187 bp overlap

EZH2 4 datasets

ChIP DND41 ENCSR000ASW.EZH2.DND41 55 bp overlap

ChIP Hep-3B2-1-7 GSE128137.EZH2.Hep-3B2-1-7 253 bp overlap

ChIP SU-DHL-6 GSE134136.EZH2.SU-DHL-6 235 bp overlap

ChIP SU-DHL-6 GSE134136.EZH2.SU-DHL-6 101 bp overlap

FOXA1 2 datasets

ChIP breast_tumor_Male_13 GSE104399.FOXA1.breast_tumor_Male_13 179 bp overlap

ChIP primary-prostate-cancer_P2_DSG GSE114737.FOXA1.primary-prostate-cancer_P2_DSG 169 bp overlap

GABPA 2 datasets

ChIP H1 ENCFF739QFD 341 bp overlap

ChIP WA01 ENCSR000BIW.GABPA.WA01 141 bp overlap

GFI1B 1 dataset

ChIP K-562 ENCSR509GDT.GFI1B.K-562 117 bp overlap

GLIS3 1 dataset

ChIP H9_plus GSE109562.GLIS3.H9_plus 319 bp overlap

HEXIM1 1 dataset

ChIP HCT-116 GSE72622.HEXIM1.HCT-116 256 bp overlap

HIF3A 1 dataset

ChIP Hep-3B2-1-7 GSE129491.HIF3A.Hep-3B2-1-7 250 bp overlap

JARID2 1 dataset

ChIP MRC-5_IPS25_CTR GSE48515.JARID2.MRC-5_IPS25_CTR 195 bp overlap

ChIP 786-O GSE86092.JUN.786-O 161 bp overlap

ChIP Karpas-299 GSE151413.JUN.Karpas-299 262 bp overlap

ChIP HEK293 ENCSR859BMR.KLF1.HEK293 142 bp overlap

ChIP WTC11 ENCFF223QFY 435 bp overlap

MED1 2 datasets

ChIP VCaP GSE148358.MED1.VCaP 130 bp overlap

ChIP VCaP_R1881 GSE148358.MED1.VCaP_R1881 258 bp overlap

ChIP Jurkat GSE59657.MYB.Jurkat 294 bp overlap

ChIP MOLT-3 GSE59657.MYB.MOLT-3 108 bp overlap

ChIP MOLT-3 GSE59657.MYB.MOLT-3 152 bp overlap

ChIP MCF-7 ENCSR000DMQ.MYC.MCF-7 117 bp overlap

MYCN 3 datasets

ChIP Kelly GSE94822.MYCN.Kelly 205 bp overlap

ChIP Kelly GSE94782.MYCN.Kelly 146 bp overlap

ChIP Kelly_sensitive GSE115249.MYCN.Kelly_sensitive 277 bp overlap

MYOD1 1 dataset

ChIP IMR-90_GM GSE128527.MYOD1.IMR-90_GM 449 bp overlap

NEUROG2 2 datasets

ChIP MRC-5_NFD_02DPT GSE75910.NEUROG2.MRC-5_NFD_02DPT 190 bp overlap

ChIP MRC-5_NFD_1DPT GSE75910.NEUROG2.MRC-5_NFD_1DPT 178 bp overlap

PCGF1 1 dataset

ChIP WA01 GSE104690.PCGF1.WA01 419 bp overlap

RAD21 10 datasets

ChIP H1 ENCFF698EWO 241 bp overlap

ChIP H1 ENCFF967OJF 245 bp overlap

ChIP HEK293_siE1A GSE130135.RAD21.HEK293_siE1A 508 bp overlap

ChIP Hep-G2 ERP000209.RAD21.Hep-G2 125 bp overlap

ChIP Hep-G2 ENCSR054FKH.RAD21.Hep-G2 100 bp overlap

ChIP IMR-90 ENCFF752PTH 237 bp overlap

ChIP IMR-90 ENCSR000EFJ.RAD21.IMR-90 162 bp overlap

ChIP MCF-7 ERP000209.RAD21.MCF-7 121 bp overlap

ChIP MCF-7_E2 ERP000209.RAD21.MCF-7_E2 111 bp overlap

ChIP RH4 GSE83726.RAD21.RH4 182 bp overlap

RBBP5 1 dataset

ChIP WA01 ENCSR000AQC.RBBP5.WA01 137 bp overlap

ChIP PANC-1 ENCSR000BJO.REST.PANC-1 164 bp overlap

RUNX1 1 dataset

ChIP VCaP_DHT24H GSE58428.RUNX1.VCaP_DHT24H 75 bp overlap

RUNX2 1 dataset

ChIP Karpas-45 GSE151819.RUNX2.Karpas-45 213 bp overlap

RYBP 2 datasets

ChIP WA01 GSE104690.RYBP.WA01 288 bp overlap

ChIP WA01 GSE104690.RYBP.WA01 168 bp overlap

SAP30 1 dataset

ChIP WA01 ENCSR000ATR.SAP30.WA01 185 bp overlap

SIN3A 6 datasets

ChIP H1 ENCFF042ZSL 459 bp overlap

ChIP H1 ENCFF896IJG 301 bp overlap

ChIP WA01 ENCSR000EBO.SIN3A.WA01 194 bp overlap

ChIP WA01 ENCSR000BIS.SIN3A.WA01 167 bp overlap

ChIP hiPSC_IB12 GSE106870.SIN3A.hiPSC_IB12 256 bp overlap

ChIP hiPSC_IID12 GSE106870.SIN3A.hiPSC_IID12 162 bp overlap

SIRT6 1 dataset

ChIP SK-MEL-239_L-C-B GSE102813.SIRT6.SK-MEL-239_L-C-B 159 bp overlap

SMARCA4 1 dataset

ChIP hiPSC GSE124903.SMARCA4.hiPSC 307 bp overlap

ChIP DKO GSE131606.SMC1.DKO 243 bp overlap

ChIP K-562 ENCSR000EGW.SMC3.K-562 121 bp overlap

ChIP WA01 ENCSR000BIR.SP1.WA01 130 bp overlap

ChIP WTC11 ENCFF688PEU 465 bp overlap

ChIP HEK293 GSE76494.SP4.HEK293 203 bp overlap

STAG1 4 datasets

ChIP Hep-G2 ERP000209.STAG1.Hep-G2 185 bp overlap

ChIP Hep-G2 ENCSR167MTG.STAG1.Hep-G2 145 bp overlap

ChIP MCF-7 ERP000209.STAG1.MCF-7 146 bp overlap

ChIP MCF-7_E2 ERP000209.STAG1.MCF-7_E2 136 bp overlap

ChIP H9_MESODERM GSE60606.T.H9_MESODERM 118 bp overlap

ChIP MOLT-3 GSE59657.TAL1.MOLT-3 145 bp overlap

ChIP hESC GSE122298.TBP.hESC 132 bp overlap

ChIP Kelly GSE94822.TBX2.Kelly 146 bp overlap

TFAP2C 3 datasets

ChIP MCF-7_ETOH GSE23852.TFAP2C.MCF-7_ETOH 230 bp overlap

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 540 bp overlap

ChIP UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc 540 bp overlap

TFAP4 2 datasets

ChIP Hep-G2 ENCSR103SZL.TFAP4.Hep-G2 172 bp overlap

ChIP K562 ENCFF727PXG 477 bp overlap

ChIP keratinocyte_diff GSE33571.TP63.keratinocyte_diff 70 bp overlap

ZBTB48 1 dataset

ChIP U2OS_ZBTB48-KO GSE96776.ZBTB48.U2OS_ZBTB48-KO 128 bp overlap

ChIP HEK293T_FLAG GSE145160.ZFX.HEK293T_FLAG 525 bp overlap

ZNF276 1 dataset

ChIP Hep-G2 ENCSR076KLJ.ZNF276.Hep-G2 76 bp overlap

ZNF512 1 dataset

ChIP WTC11 ENCFF086TTM 301 bp overlap

ZNF550 1 dataset

ChIP Hep-G2 ENCSR198BHH.ZNF550.Hep-G2 162 bp overlap

ZNF770 1 dataset

ChIP HEK293 GSE76494.ZNF770.HEK293 211 bp overlap

ZSCAN22 1 dataset

ChIP HEK293 GSE76494.ZSCAN22.HEK293 211 bp overlap