chr2 : 20,045,819 – 20,046,308
489 bp 75 TFs 2 linked genes
This 489 bp open chromatin element is linked to LAPTM4A and LAPTM4A-DT and is bound by 75 transcription factors.
Linked Genes
2 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
LAPTM4A 5.3 kb Proximal Proximity
LAPTM4A-DT 5.8 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr2:20,040,819 – 20,051,308
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
75 transcription factors
Source
Cell type
None 1 dataset
ChIP HepG2 ENCFF731CFD 489 bp overlap
ARID1A 1 dataset
ChIP NGP GSE134626.ARID1A.NGP 209 bp overlap
BNC2 2 datasets
ChIP SK-N-SH ENCFF174EMC 239 bp overlap
ChIP SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour ENCSR754GYI.BNC2.SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour 207 bp overlap
BRD4 3 datasets
ChIP Kelly_resistant_JQ1 GSE103030.BRD4.Kelly_resistant_JQ1 213 bp overlap
ChIP Kelly_sensitive GSE103030.BRD4.Kelly_sensitive 193 bp overlap
ChIP SK-N-BE2-C_Naive-veh GSE107706.BRD4.SK-N-BE2-C_Naive-veh 218 bp overlap
CBFA2T3 2 datasets
ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 191 bp overlap
ChIP K562 ENCFF673OEZ 300 bp overlap
CHD2 2 datasets
ChIP SK-N-SH ENCFF669KMB 114 bp overlap
ChIP SK-N-SH ENCSR274SLQ.CHD2.SK-N-SH 203 bp overlap
CREB5 2 datasets
ChIP SK-N-SH ENCFF144PMI 192 bp overlap
ChIP SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour ENCSR758GOA.CREB5.SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour 212 bp overlap
CSRNP3 1 dataset
ChIP SK-N-SH ENCFF710BXD 265 bp overlap
CTCFL 1 dataset
ChIP Kelly_resistant_JQ1 GSE103030.CTCFL.Kelly_resistant_JQ1 209 bp overlap
EBF3_P177L 1 dataset
ChIP SK-N-SH GSE90682.EBF3_P177L.SK-N-SH 218 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 264 bp overlap
EP300 2 datasets
ChIP SK-N-SH ENCFF829RWA 169 bp overlap
ChIP SK-N-SH ENCSR000EHV.EP300.SK-N-SH 271 bp overlap
ESR1_pS118 1 dataset
ChIP MCF-7_E2_sc GSE117569.ESR1_pS118.MCF-7_E2_sc 177 bp overlap
ESRRG 1 dataset
ChIP SK-N-SH ENCFF394HLU 163 bp overlap
ETV5::HOXA2 2 datasets
Motif DE_36h DE_36h-ETV5HOXA2_MA1948.2 12 bp overlap
Motif DE_48h DE_48h-ETV5HOXA2_MA1948.2 12 bp overlap
FOXA2 3 datasets
ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.FOXA2.BJ1-hTERT_FOXA2_GATA4_Coexp 240 bp overlap
ChIP DE DE-FOXA2-1 489 bp overlap
ChIP DE DE-FOXA2-2 489 bp overlap
FOXJ3 1 dataset
ChIP SK-N-SH ENCFF124KVL 383 bp overlap
GATA1 8 datasets
ChIP CD34_Day7_30min GSE104676.GATA1.CD34_Day7_30min 65 bp overlap
ChIP CD34_ERYTH_BIO GSE29194.GATA1.CD34_ERYTH_BIO 191 bp overlap
ChIP CD34_ERYTH_BMP GSE29194.GATA1.CD34_ERYTH_BMP 216 bp overlap
ChIP K-562 GSE107726.GATA1.K-562 197 bp overlap
ChIP K-562_dCas9-LSD1 GSE132212.GATA1.K-562_dCas9-LSD1 181 bp overlap
ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 210 bp overlap
ChIP erythroblast ENCSR000EXP.GATA1.erythroblast 169 bp overlap
ChIP erythroid_Don003 GSE137982.GATA1.erythroid_Don003 169 bp overlap
GATA2 13 datasets
Motif DE_36h DE_36h-GATA2_MA0036.4 7 bp overlap
Motif DE_48h DE_48h-GATA2_MA0036.4 7 bp overlap
ChIP ESF GSE108408.GATA2.ESF 233 bp overlap
ChIP Hep-G2 ENCSR897LDT.GATA2.Hep-G2 166 bp overlap
ChIP HepG2 ENCFF905PYM 344 bp overlap
ChIP SH-SY5Y ENCFF485YIB 213 bp overlap
ChIP SH-SY5Y ENCSR000EYB.GATA2.SH-SY5Y 336 bp overlap
ChIP SK-N-SH ENCFF764OZD 276 bp overlap
ChIP SK-N-SH ENCSR706VOO.GATA2.SK-N-SH 268 bp overlap
ChIP TF1 GSE73207.GATA2.TF1 202 bp overlap
ChIP dermal-fibroblast_alone GSE51025.GATA2.dermal-fibroblast_alone 220 bp overlap
ChIP primary-endometrial-stromal-cell_IVD_P2 GSE145673.GATA2.primary-endometrial-stromal-cell_IVD_P2 145 bp overlap
ChIP primary-endometrial-stromal-cell_Veh_P2 GSE145673.GATA2.primary-endometrial-stromal-cell_Veh_P2 272 bp overlap
GATA3 14 datasets
ChIP BE2C GSE65664.GATA3.BE2C 287 bp overlap
ChIP CLB-Ga GSE90683.GATA3.CLB-Ga 293 bp overlap
ChIP Kelly GSE94822.GATA3.Kelly 226 bp overlap
ChIP Kelly GSE65664.GATA3.Kelly 227 bp overlap
ChIP MCF-7 ENCFF352QVM 449 bp overlap
ChIP MCF-7 GSE51274.GATA3.MCF-7 194 bp overlap
ChIP MCF-7_sgScr GSE133072.GATA3.MCF-7_sgScr 160 bp overlap
ChIP NGP GSE65664.GATA3.NGP 221 bp overlap
ChIP SH-SY5Y ENCFF475HYF 245 bp overlap
ChIP SH-SY5Y ENCFF475HYF 460 bp overlap
ChIP SH-SY5Y ENCSR000EXZ.GATA3.SH-SY5Y 385 bp overlap
ChIP SH-SY5Y GSE65664.GATA3.SH-SY5Y 214 bp overlap
ChIP SK-N-BE2-C GSE94822.GATA3.SK-N-BE2-C 245 bp overlap
ChIP SK-N-SH ENCFF040SSB 237 bp overlap
GATA3_Nter 1 dataset
ChIP T-47D_CR3flp GSE99479.GATA3_Nter.T-47D_CR3flp 155 bp overlap
GATA4 7 datasets
ChIP DE DE-GATA4-1 489 bp overlap
ChIP DE DE-GATA4-2 489 bp overlap
Motif DE_36h DE_36h-GATA4_MA0482.3 8 bp overlap
Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap
ChIP Hep-G2 GSE135714.GATA4.Hep-G2 267 bp overlap
ChIP foregut GSE117136.GATA4.foregut 331 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 320 bp overlap
GATA5 2 datasets
Motif DE_36h DE_36h-GATA5_MA0766.3 8 bp overlap
Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap
GATA6 16 datasets
ChIP Caco-2_PROLIF GSE23436.GATA6.Caco-2_PROLIF 220 bp overlap
ChIP DE DE-GATA6-1 419 bp overlap
ChIP DE DE-GATA6-2 489 bp overlap
Motif DE_36h DE_36h-GATA6_MA1104.3 8 bp overlap
Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 436 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 489 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 428 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 429 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 489 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 396 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 387 bp overlap
ChIP foregut GSE117136.GATA6.foregut 257 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 239 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 252 bp overlap
ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 165 bp overlap
GLIS1 2 datasets
ChIP HEK293 ENCFF299RSE 281 bp overlap
ChIP HEK293 ENCSR482BBZ.GLIS1.HEK293 258 bp overlap
Gata3 2 datasets
Motif DE_36h DE_36h-Gata3_MA0037.5 8 bp overlap
Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap
HAND2 3 datasets
ChIP CLB-Ga GSE90683.HAND2.CLB-Ga 329 bp overlap
ChIP Kelly GSE94822.HAND2.Kelly 239 bp overlap
ChIP SK-N-BE2-C GSE94822.HAND2.SK-N-BE2-C 279 bp overlap
HDAC2 1 dataset
ChIP K-562 ENCSR893WSB.HDAC2.K-562 124 bp overlap
HSF1 3 datasets
ChIP MCF-10A_HEAT GSE38901.HSF1.MCF-10A_HEAT 71 bp overlap
ChIP MCF-7_hyperthermia-15min GSE137558.HSF1.MCF-7_hyperthermia-15min 189 bp overlap
ChIP NCI-H838 GSE38901.HSF1.NCI-H838 71 bp overlap
IRF3 1 dataset
ChIP SK-N-SH ENCFF921DIM 201 bp overlap
ISL1 2 datasets
ChIP SK-N-BE2-C GSE94822.ISL1.SK-N-BE2-C 278 bp overlap
ChIP SK-N-SH ENCFF285GEQ 192 bp overlap
KDM1A 3 datasets
ChIP SH-SY5Y_B0 GSE58258.KDM1A.SH-SY5Y_B0 185 bp overlap
ChIP SH-SY5Y_B0_SHLSD18A GSE58258.KDM1A.SH-SY5Y_B0_SHLSD18A 160 bp overlap
ChIP SH-SY5Y_B3 GSE58258.KDM1A.SH-SY5Y_B3 258 bp overlap
MAF 2 datasets
Motif DE_36h DE_36h-MAF_MA1520.2 13 bp overlap
Motif DE_48h DE_48h-MAF_MA1520.2 13 bp overlap
MAFA 2 datasets
Motif DE_36h DE_36h-MAFA_MA1521.2 13 bp overlap
Motif DE_48h DE_48h-MAFA_MA1521.2 13 bp overlap
MAML3 1 dataset
ChIP SK-N-SH GSE69119.MAML3.SK-N-SH 276 bp overlap
MXI1 2 datasets
ChIP SK-N-SH ENCFF746HVJ 315 bp overlap
ChIP SK-N-SH ENCSR000EIA.MXI1.SK-N-SH 189 bp overlap
MYC 1 dataset
ChIP NB69 GSE138295.MYC.NB69 227 bp overlap
MYCN 5 datasets
ChIP COG-N-415 GSE138295.MYCN.COG-N-415 183 bp overlap
ChIP Kelly GSE94822.MYCN.Kelly 248 bp overlap
ChIP LA-N-5 GSE138295.MYCN.LA-N-5 275 bp overlap
ChIP NB-1643 GSE94782.MYCN.NB-1643 216 bp overlap
ChIP SK-N-BE2-C GSE94822.MYCN.SK-N-BE2-C 136 bp overlap
NFIC 1 dataset
ChIP SK-N-SH ENCSR000BSV.NFIC.SK-N-SH 144 bp overlap
OSR2 3 datasets
ChIP HEK293 ENCFF875BDB 193 bp overlap
ChIP HEK293 ENCSR324LTM.OSR2.HEK293 244 bp overlap
ChIP HEK293 GSE76494.OSR2.HEK293 147 bp overlap
PHOX2B 2 datasets
ChIP CLB-Ga GSE90683.PHOX2B.CLB-Ga 274 bp overlap
ChIP SK-N-BE2-C GSE94822.PHOX2B.SK-N-BE2-C 86 bp overlap
PITX3 1 dataset
ChIP SH-SY5Y GSE93275.PITX3.SH-SY5Y 428 bp overlap
POLR2A 1 dataset
ChIP SK-N-SH ENCFF683PFH 316 bp overlap
PRDM1 2 datasets
Motif DE_36h DE_36h-PRDM1_MA0508.4 7 bp overlap
Motif DE_48h DE_48h-PRDM1_MA0508.4 7 bp overlap
PRDM4 1 dataset
ChIP HEK293 ENCFF069PHD 370 bp overlap
PRDM6 1 dataset
ChIP HEK293 ENCSR892QHR.PRDM6.HEK293 188 bp overlap
RAD21 1 dataset
ChIP SK-N-SH ENCSR000EHX.RAD21.SK-N-SH 149 bp overlap
RBPJ 2 datasets
Motif DE_36h DE_36h-RBPJ_MA1116.2 6 bp overlap
Motif DE_48h DE_48h-RBPJ_MA1116.2 6 bp overlap
RCOR1 2 datasets
ChIP SK-N-SH ENCFF518EXB 183 bp overlap
ChIP SK-N-SH ENCSR009TKN.RCOR1.SK-N-SH 253 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 397 bp overlap
SMAD2_3 3 datasets
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 66 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 386 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 386 bp overlap
SMAD4 1 dataset
ChIP Caco-2 GSE112946.SMAD4.Caco-2 177 bp overlap
SMARCA4 3 datasets
ChIP NGP GSE134626.SMARCA4.NGP 231 bp overlap
ChIP NGP_ARID1A-mut1 GSE134626.SMARCA4.NGP_ARID1A-mut1 235 bp overlap
ChIP NGP_ARID1A-mut2 GSE134626.SMARCA4.NGP_ARID1A-mut2 229 bp overlap
SNAI2 3 datasets
ChIP SK-N-SH ENCFF449PID 221 bp overlap
ChIP SK-N-SH ENCFF449PID 337 bp overlap
ChIP SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour ENCSR106GVM.SNAI2.SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour 196 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 462 bp overlap
SRF 2 datasets
Motif DE_36h DE_36h-SRF_MA0083.3 16 bp overlap
Motif DE_48h DE_48h-SRF_MA0083.3 16 bp overlap
T 1 dataset
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 205 bp overlap
TAF1 1 dataset
ChIP SK-N-SH ENCSR000BQF.TAF1.SK-N-SH 110 bp overlap
TAL1 4 datasets
ChIP CD34 GSE52924.TAL1.CD34 146 bp overlap
ChIP K-562 ENCSR000EHB.TAL1.K-562 114 bp overlap
ChIP K-562_dCas9-KRAB GSE132212.TAL1.K-562_dCas9-KRAB 151 bp overlap
ChIP ProEs GSE59087.TAL1.ProEs 139 bp overlap
TBX2 1 dataset
ChIP Kelly GSE94822.TBX2.Kelly 237 bp overlap
TCF12 1 dataset
ChIP SK-N-SH ENCFF147AHB 183 bp overlap
TCF4 1 dataset
ChIP SK-N-SH ENCFF270OWF 349 bp overlap
TEAD4 2 datasets
ChIP BE2C GSE84389.TEAD4.BE2C 208 bp overlap
ChIP SK-N-BE2 GSE84389.TEAD4.SK-N-BE2 208 bp overlap
TFAP2B 1 dataset
ChIP SK-N-SH ENCFF869XXQ 271 bp overlap
TOX2 2 datasets
ChIP SK-N-SH ENCFF415OYE 78 bp overlap
ChIP SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour ENCSR226NRS.TOX2.SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour 236 bp overlap
TRPS1 2 datasets
Motif DE_36h DE_36h-TRPS1_MA1970.2 8 bp overlap
Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap
TSHZ2 3 datasets
ChIP SK-N-SH ENCFF182EBB 232 bp overlap
ChIP SK-N-SH ENCFF182EBB 381 bp overlap
ChIP SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour ENCSR282NLQ.TSHZ2.SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour 245 bp overlap
TWIST1 2 datasets
ChIP BE2C GSE80151.TWIST1.BE2C 215 bp overlap
ChIP SK-N-BE2-C GSE80151.TWIST1.SK-N-BE2-C 215 bp overlap
YY1 2 datasets
ChIP Hep-G2_NC GSE120104.YY1.Hep-G2_NC 247 bp overlap
ChIP SK-N-SH ENCSR000BLZ.YY1.SK-N-SH 155 bp overlap
ZBTB33 1 dataset
ChIP HepG2 ENCFF778UKV 272 bp overlap
ZBTB7A 1 dataset
ChIP HUDEP-2 GSE103445.ZBTB7A.HUDEP-2 206 bp overlap
ZNF18 2 datasets
ChIP HEK293 ENCFF066NGR 369 bp overlap
ChIP HEK293 ENCSR977HTH.ZNF18.HEK293 448 bp overlap
ZNF75D 2 datasets
Motif DE_36h DE_36h-ZNF75D_MA1601.2 12 bp overlap
Motif DE_48h DE_48h-ZNF75D_MA1601.2 12 bp overlap
ZNF768 2 datasets
Motif DE_36h DE_36h-ZNF768_MA1731.2 9 bp overlap
Motif DE_48h DE_48h-ZNF768_MA1731.2 9 bp overlap
ZNF8 1 dataset
ChIP SK-N-SH ENCFF131SMT 323 bp overlap
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