chr20 : 59,308,756 – 59,309,130
374 bp 64 TFs 1 linked gene
This 374 bp open chromatin element is linked to EDN3 and is bound by 64 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
EDN3 8.0 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr20:59,303,756 – 59,314,130
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
64 transcription factors
Source
Cell type
ARID1B 2 datasets
ChIP K-562 ENCSR822CCM.ARID1B.K-562 354 bp overlap
ChIP K562 ENCFF938UXQ 159 bp overlap
ARNTL 1 dataset
ChIP U2OS_DMOG GSE85096.ARNTL.U2OS_DMOG 54 bp overlap
BRD4 6 datasets
ChIP COLO-205 GSE73319.BRD4.COLO-205 183 bp overlap
ChIP Kelly_sensitive GSE103030.BRD4.Kelly_sensitive 328 bp overlap
ChIP P493-6_MYC_1H GSE42262.BRD4.P493-6_MYC_1H 180 bp overlap
ChIP SW480 GSE73319.BRD4.SW480 271 bp overlap
ChIP SW480 GSE110473.BRD4.SW480 370 bp overlap
ChIP SW480_16h_TNF-a GSE110473.BRD4.SW480_16h_TNF-a 298 bp overlap
CBFA2T2 1 dataset
ChIP K-562 ENCSR699PVC.CBFA2T2.K-562 218 bp overlap
CBFA2T3 2 datasets
ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 374 bp overlap
ChIP K562 ENCFF673OEZ 202 bp overlap
CDX2 3 datasets
ChIP Caco-2_DIFF GSE23436.CDX2.Caco-2_DIFF 304 bp overlap
ChIP Caco-2_PROLIF GSE23436.CDX2.Caco-2_PROLIF 151 bp overlap
ChIP adult-duodenal-cell GSE115314.CDX2.adult-duodenal-cell 328 bp overlap
CEBPD 1 dataset
ChIP K-562 ENCSR000BVY.CEBPD.K-562 133 bp overlap
CREM 1 dataset
ChIP K-562 ENCSR077DKV.CREM.K-562 93 bp overlap
CTBP1 1 dataset
ChIP K-562 ENCSR201NQZ.CTBP1.K-562 367 bp overlap
CTCF 17 datasets
ChIP Caco-2 ENCFF753NZV 302 bp overlap
ChIP Caco-2 ENCFF753NZV 307 bp overlap
ChIP Caco-2 ENCFF934QYS 217 bp overlap
ChIP Caco-2 ENCSR000DQN.CTCF.Caco-2 146 bp overlap
ChIP Peyer's patch ENCFF701KWW 350 bp overlap
ChIP Peyer's patch ENCFF746TCR 136 bp overlap
ChIP Peyer's patch ENCFF746TCR 206 bp overlap
ChIP Peyers-patch ENCSR375VXU.CTCF.Peyers-patch 365 bp overlap
ChIP Peyers-patch ENCSR419ANE.CTCF.Peyers-patch 231 bp overlap
ChIP Peyers-patch ENCSR799WDT.CTCF.Peyers-patch 156 bp overlap
ChIP body of pancreas ENCFF798MEO 297 bp overlap
ChIP colon_transverse ENCSR102CSD.CTCF.colon_transverse 347 bp overlap
ChIP colon_transverse ENCSR833FWC.CTCF.colon_transverse 240 bp overlap
ChIP endodermal cell ENCFF471YCZ 370 bp overlap
ChIP pancreas_body ENCSR408XTO.CTCF.pancreas_body 175 bp overlap
ChIP transverse colon ENCFF077CMZ 331 bp overlap
ChIP transverse colon ENCFF749DPF 374 bp overlap
Cebpa 1 dataset
ChIP BLaER1 ENCFF031ISE 253 bp overlap
EP300 1 dataset
ChIP transverse colon ENCFF258CAS 241 bp overlap
ESR1 7 datasets
ChIP MCF-7 GSE68355.ESR1.MCF-7 244 bp overlap
ChIP MCF-7_DHT GSE99626.ESR1.MCF-7_DHT 350 bp overlap
ChIP MCF-7_PROG GSE68355.ESR1.MCF-7_PROG 335 bp overlap
ChIP MCF-7_R5020 GSE68355.ESR1.MCF-7_R5020 251 bp overlap
ChIP MCF-7_aldosterone GSE99626.ESR1.MCF-7_aldosterone 305 bp overlap
ChIP MCF-7_parental GSE123284.ESR1.MCF-7_parental 164 bp overlap
ChIP MCF-7_parental_4-hydroxytamoxifen GSE123284.ESR1.MCF-7_parental_4-hydroxytamoxifen 291 bp overlap
EZH2 2 datasets
ChIP A-1847_CARM1-KO GSE95643.EZH2.A-1847_CARM1-KO 374 bp overlap
ChIP THP-1 GSE135024.EZH2.THP-1 332 bp overlap
FOXA2 1 dataset
ChIP Caco-2 GSE66218.FOXA2.Caco-2 132 bp overlap
FOXP4 1 dataset
ChIP Hep-G2 ENCSR232LLP.FOXP4.Hep-G2 143 bp overlap
GATA1 5 datasets
ChIP K-562 GSE107726.GATA1.K-562 245 bp overlap
ChIP K-562 ENCSR000EFT.GATA1.K-562 168 bp overlap
ChIP K-562_dCas9-LSD1 GSE132212.GATA1.K-562_dCas9-LSD1 226 bp overlap
ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 177 bp overlap
ChIP K562 ENCFF094CMK 245 bp overlap
GATA2 8 datasets
ChIP Hep-G2 ENCSR897LDT.GATA2.Hep-G2 279 bp overlap
ChIP HepG2 ENCFF905PYM 294 bp overlap
ChIP K-562 ENCSR000EWG.GATA2.K-562 296 bp overlap
ChIP K-562 ENCSR000BKM.GATA2.K-562 127 bp overlap
ChIP K562 ENCFF513FTZ 293 bp overlap
ChIP LNCaP_CSFCS GSE69043.GATA2.LNCaP_CSFCS 177 bp overlap
ChIP WA09 GSE105081.GATA2.WA09 143 bp overlap
ChIP hiPSC_SLC6ebs GSE107639.GATA2.hiPSC_SLC6ebs 182 bp overlap
GATA3 7 datasets
ChIP CLB-Ga GSE90683.GATA3.CLB-Ga 193 bp overlap
ChIP Jurkat GSE76181.GATA3.Jurkat 299 bp overlap
ChIP Jurkat GSE120063.GATA3.Jurkat 239 bp overlap
ChIP Kelly GSE65664.GATA3.Kelly 265 bp overlap
ChIP MCF-7 ENCFF352QVM 357 bp overlap
ChIP MCF-7 ENCFF437NQS 181 bp overlap
ChIP MCF-7 GSE51274.GATA3.MCF-7 216 bp overlap
GATA4 7 datasets
ChIP DE DE-GATA4-1 374 bp overlap
ChIP DE DE-GATA4-2 374 bp overlap
ChIP ESO-26 GSE132813.GATA4.ESO-26 337 bp overlap
ChIP YCC-3 GSE51705.GATA4.YCC-3 307 bp overlap
ChIP foregut GSE117136.GATA4.foregut 374 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 374 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 374 bp overlap
GATA6 21 datasets
ChIP AGS GSE51705.GATA6.AGS 374 bp overlap
ChIP Caco-2_PROLIF GSE23436.GATA6.Caco-2_PROLIF 234 bp overlap
ChIP DE DE-GATA6-1 298 bp overlap
ChIP DE DE-GATA6-2 374 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 349 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 374 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 374 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 374 bp overlap
ChIP ESO-26 GSE132680.GATA6.ESO-26 371 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 374 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 374 bp overlap
ChIP HUG1N GSE51936.GATA6.HUG1N 229 bp overlap
ChIP KATO-III GSE51705.GATA6.KATO-III 238 bp overlap
ChIP PATU8988 GSE47535.GATA6.PATU8988 374 bp overlap
ChIP YCC-3 GSE51705.GATA6.YCC-3 374 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 374 bp overlap
ChIP foregut GSE117136.GATA6.foregut 374 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 350 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 374 bp overlap
ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 351 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 319 bp overlap
GFI1B 1 dataset
ChIP K-562 ENCSR509GDT.GFI1B.K-562 150 bp overlap
GRHL2 1 dataset
ChIP MCF-7_E2_45min GSE109820.GRHL2.MCF-7_E2_45min 251 bp overlap
HAND2 3 datasets
ChIP CLB-Ga GSE90683.HAND2.CLB-Ga 374 bp overlap
ChIP Kelly GSE94822.HAND2.Kelly 374 bp overlap
ChIP SK-N-BE2-C GSE94822.HAND2.SK-N-BE2-C 146 bp overlap
HDAC1 2 datasets
ChIP K-562 ENCSR387UWP.HDAC1.K-562 374 bp overlap
ChIP K562 ENCFF968WBH 374 bp overlap
HDAC2 4 datasets
ChIP K-562 ENCSR893WSB.HDAC2.K-562 245 bp overlap
ChIP K-562 ENCSR000BMG.HDAC2.K-562 171 bp overlap
ChIP K562 ENCFF744ALD 313 bp overlap
ChIP MCF-7 ENCSR000BTP.HDAC2.MCF-7 149 bp overlap
HNF4A 8 datasets
ChIP Caco-2_DIFF GSE23436.HNF4A.Caco-2_DIFF 373 bp overlap
ChIP Caco-2_PROLIF GSE23436.HNF4A.Caco-2_PROLIF 289 bp overlap
ChIP GP5D GSE51234.HNF4A.GP5D 374 bp overlap
ChIP Hep-G2 ENCSR469FBY.HNF4A.Hep-G2 251 bp overlap
ChIP IM95 GSE114018.HNF4A.IM95 344 bp overlap
ChIP KATO-III GSE114018.HNF4A.KATO-III 277 bp overlap
ChIP LoVo_PHASES GSE51290.HNF4A.LoVo_PHASES 374 bp overlap
ChIP hiPSC GSE104613.HNF4A.hiPSC 374 bp overlap
HNRNPH1 2 datasets
ChIP Hep-G2 ENCSR066FXN.HNRNPH1.Hep-G2 205 bp overlap
ChIP Hep-G2 GSE120104.HNRNPH1.Hep-G2 206 bp overlap
KDM1A 3 datasets
ChIP K-562 GSE117944.KDM1A.K-562 374 bp overlap
ChIP K-562 ENCSR908CMW.KDM1A.K-562 369 bp overlap
ChIP K-562_Wnt GSE117944.KDM1A.K-562_Wnt 212 bp overlap
KLF5 4 datasets
ChIP ESO-26 GSE132680.KLF5.ESO-26 346 bp overlap
ChIP GP5D GSE51234.KLF5.GP5D 213 bp overlap
ChIP KATO-III GSE51705.KLF5.KATO-III 175 bp overlap
ChIP YCC-3 GSE51705.KLF5.YCC-3 141 bp overlap
KMT2B-D 1 dataset
ChIP SW480 GSE115985.KMT2B-D.SW480 223 bp overlap
MED1 1 dataset
ChIP RH4 GSE83726.MED1.RH4 183 bp overlap
MYB 1 dataset
ChIP DU528 GSE94000.MYB.DU528 374 bp overlap
MYC 1 dataset
ChIP GP5D GSE51234.MYC.GP5D 211 bp overlap
MYCN 3 datasets
ChIP Kelly GSE94822.MYCN.Kelly 276 bp overlap
ChIP Kelly_sensitive GSE115249.MYCN.Kelly_sensitive 139 bp overlap
ChIP RH4 GSE83726.MYCN.RH4 255 bp overlap
MYOD1 1 dataset
ChIP RH4 GSE83726.MYOD1.RH4 231 bp overlap
NR2C1 3 datasets
ChIP K-562 ENCSR742IDN.NR2C1.K-562 321 bp overlap
ChIP K-562 ENCSR178DEG.NR2C1.K-562 244 bp overlap
ChIP K562 ENCFF568JLK 302 bp overlap
NR2C2 1 dataset
ChIP K-562 ENCSR750LYM.NR2C2.K-562 197 bp overlap
NR2F1 1 dataset
ChIP K-562 ENCSR970NKQ.NR2F1.K-562 374 bp overlap
NR2F2 3 datasets
ChIP K-562 ENCSR000BRS.NR2F2.K-562 200 bp overlap
ChIP MCF-7 ENCFF329FZB 327 bp overlap
ChIP MCF-7 ENCSR000BUY.NR2F2.MCF-7 301 bp overlap
NR2F6 2 datasets
ChIP K-562 ENCSR707QWA.NR2F6.K-562 219 bp overlap
ChIP K562 ENCFF674RQA 365 bp overlap
NR3C1 1 dataset
ChIP A-549 ENCSR000BJR.NR3C1.A-549 104 bp overlap
PDX1 3 datasets
ChIP hiPSC GSE125768.PDX1.hiPSC 273 bp overlap
ChIP hiPSC_derived_PPs GSE106949.PDX1.hiPSC_derived_PPs 212 bp overlap
ChIP pancreatic-progenitor GSE117136.PDX1.pancreatic-progenitor 249 bp overlap
PGR 2 datasets
ChIP MCF-7_PROG GSE68355.PGR.MCF-7_PROG 228 bp overlap
ChIP MCF-7_R5020 GSE68355.PGR.MCF-7_R5020 315 bp overlap
PML 1 dataset
ChIP K-562 ENCSR000BQY.PML.K-562 151 bp overlap
POLR2A 7 datasets
ChIP Peyer's patch ENCFF767HVN 304 bp overlap
ChIP transverse colon ENCFF193UMS 143 bp overlap
ChIP transverse colon ENCFF193UMS 258 bp overlap
ChIP transverse colon ENCFF607LKE 140 bp overlap
ChIP transverse colon ENCFF610RWV 278 bp overlap
ChIP transverse colon ENCFF610RWV 63 bp overlap
ChIP transverse colon ENCFF840PXT 309 bp overlap
PROX1 1 dataset
ChIP SW480 GSE60390.PROX1.SW480 156 bp overlap
RAD21 1 dataset
ChIP GP5D GSE51234.RAD21.GP5D 326 bp overlap
RCOR1 1 dataset
ChIP K562 ENCFF216EEJ 252 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 342 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 374 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 323 bp overlap
SMAD2_3 4 datasets
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 330 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 308 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 263 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 317 bp overlap
SMAD4 1 dataset
ChIP Caco-2 GSE112946.SMAD4.Caco-2 342 bp overlap
SMC3 1 dataset
ChIP GP5D GSE51234.SMC3.GP5D 258 bp overlap
SNAI2 1 dataset
ChIP RD GSE137168.SNAI2.RD 168 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 229 bp overlap
STAT1 1 dataset
ChIP HeLa-S3 ENCSR000EZK.STAT1.HeLa-S3 241 bp overlap
STAT5A 2 datasets
ChIP K-562 ENCSR000BRR.STAT5A.K-562 165 bp overlap
ChIP K562 ENCFF226BTJ 307 bp overlap
TAL1 12 datasets
ChIP Jurkat GSE29180.TAL1.Jurkat 139 bp overlap
ChIP K-562 ENCSR106FRG.TAL1.K-562 374 bp overlap
ChIP K-562 ENCSR000EHB.TAL1.K-562 227 bp overlap
ChIP K-562 GSE107726.TAL1.K-562 238 bp overlap
ChIP K-562_dCas9-KRAB GSE132212.TAL1.K-562_dCas9-KRAB 211 bp overlap
ChIP K-562_dCas9-LSD1 GSE132212.TAL1.K-562_dCas9-LSD1 255 bp overlap
ChIP K-562_enCRISPRi-KL GSE132212.TAL1.K-562_enCRISPRi-KL 223 bp overlap
ChIP K-562_enCRISPRi-LK GSE132212.TAL1.K-562_enCRISPRi-LK 208 bp overlap
ChIP K-562_sgGal4 GSE132212.TAL1.K-562_sgGal4 361 bp overlap
ChIP K562 ENCFF620GMX 179 bp overlap
ChIP K562 ENCFF661CCK 264 bp overlap
ChIP PRIMA2 GSE33850.TAL1.PRIMA2 180 bp overlap
TBX2 1 dataset
ChIP Kelly GSE94822.TBX2.Kelly 205 bp overlap
TCF12 2 datasets
ChIP K-562 ENCSR744WOO.TCF12.K-562 218 bp overlap
ChIP K562 ENCFF931DJY 339 bp overlap
TCF3 2 datasets
ChIP K-562 ENCSR970OJY.TCF3.K-562 159 bp overlap
ChIP K562 ENCFF319QZT 368 bp overlap
TEAD4 1 dataset
ChIP K562 ENCFF673NIK 161 bp overlap
TFAP2A 1 dataset
ChIP WA09 GSE105081.TFAP2A.WA09 270 bp overlap
TRPS1 1 dataset
ChIP MCF-7 GSE133072.TRPS1.MCF-7 260 bp overlap
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