chr19:38,043,611–38,044,643

chr19 : 38,043,611 – 38,044,643

1,032 bp 66 TFs 8 linked genes

This 1.0 kb open chromatin element is linked to 8 target genes and is bound by 66 transcription factors.

Linked Genes

8 genes

Gene	Expression	Dist. to TSS	Distance	Link type
SIPA1L3		136.6 kb	Distal	Multiome+HiCAR
PPP1R14A		212.7 kb	Distal	Multiome
SPINT2		220.7 kb	Distal	Multiome
ENSG00000291089		226.5 kb	Distal	Multiome
ZNF573		226.6 kb	Distal	Multiome
C19orf33		260.4 kb	Distal	Multiome
YIF1B		272.1 kb	Distal	Multiome
KCNK6		276.0 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

66 transcription factors

ASCL1 1 dataset

ChIP NCI-H889 GSE69394.ASCL1.NCI-H889 111 bp overlap

BACH2 1 dataset

ChIP B-cell_IL2 GSE102460.BACH2.B-cell_IL2 179 bp overlap

BCL3 2 datasets

ChIP GM12878 ENCFF854PAY 351 bp overlap

ChIP GM12878 ENCSR000BNQ.BCL3.GM12878 224 bp overlap

ChIP OCI-Ly1 GSE29282.BCL6.OCI-Ly1 334 bp overlap

ChIP HUES-64 GSE104059.BRD1.HUES-64 218 bp overlap

ChIP MV4-11_IBET151_500nM GSE120715.BRD3.MV4-11_IBET151_500nM 134 bp overlap

BRD4 12 datasets

ChIP CLL_patient1 GSE109411.BRD4.CLL_patient1 344 bp overlap

ChIP CLL_patient1 GSE109411.BRD4.CLL_patient1 454 bp overlap

ChIP CLL_patient1_4h_CpG GSE109411.BRD4.CLL_patient1_4h_CpG 410 bp overlap

ChIP CLL_patient1_4h_CpG_BET GSE109411.BRD4.CLL_patient1_4h_CpG_BET 466 bp overlap

ChIP CLL_patient2_4h_CpG_BET GSE109411.BRD4.CLL_patient2_4h_CpG_BET 193 bp overlap

ChIP CLL_patient3_4h_CpG GSE109411.BRD4.CLL_patient3_4h_CpG 276 bp overlap

ChIP CLL_patient3_4h_CpG_BET GSE109411.BRD4.CLL_patient3_4h_CpG_BET 269 bp overlap

ChIP CLL_patient4 GSE109411.BRD4.CLL_patient4 841 bp overlap

ChIP CLL_patient4_4h_CpG GSE109411.BRD4.CLL_patient4_4h_CpG 412 bp overlap

ChIP Kelly_resistant GSE103030.BRD4.Kelly_resistant 197 bp overlap

ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 209 bp overlap

ChIP retina_AB1-FW23 GSE86981.BRD4.retina_AB1-FW23 542 bp overlap

CBX2 2 datasets

ChIP HEK293T GSE34774.CBX2.HEK293T 326 bp overlap

ChIP HEK293T GSE34774.CBX2.HEK293T 264 bp overlap

CREB1 1 dataset

ChIP MCF-7 ENCSR897JAS.CREB1.MCF-7 218 bp overlap

CTBP1 1 dataset

ChIP K-562 ENCSR201NQZ.CTBP1.K-562 396 bp overlap

CTCF 3 datasets

ChIP B cell ENCFF500PZO 70 bp overlap

ChIP RWPE2 ENCFF911IEE 148 bp overlap

ChIP epithelial cell of prostate ENCFF086GTI 59 bp overlap

Cebpa 4 datasets

ChIP BLaER1 ENCFF031ISE 444 bp overlap

ChIP BLaER1 ENCFF093OYK 251 bp overlap

ChIP BLaER1 ENCFF274GAT 377 bp overlap

ChIP BLaER1 ENCFF335XTP 359 bp overlap

ChIP K-562 ENCSR219BXP.DPF2.K-562 240 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 177 bp overlap

ESR1 36 datasets

ChIP Ishikawa_siNTC-96h GSE129803.ESR1.Ishikawa_siNTC-96h 218 bp overlap

ChIP MCF-7 GSE68355.ESR1.MCF-7 236 bp overlap

ChIP MCF-7 GSE117492.ESR1.MCF-7 324 bp overlap

ChIP MCF-7 GSE103023.ESR1.MCF-7 178 bp overlap

ChIP MCF-7 GSE76893.ESR1.MCF-7 170 bp overlap

ChIP MCF-7_DMSO GSE125594.ESR1.MCF-7_DMSO 389 bp overlap

ChIP MCF-7_E2 ERP000209.ESR1.MCF-7_E2 251 bp overlap

ChIP MCF-7_E2 GSE14664.ESR1.MCF-7_E2 116 bp overlap

ChIP MCF-7_E2-10min-ERalpha GSE94023.ESR1.MCF-7_E2-10min-ERalpha 286 bp overlap

ChIP MCF-7_E2-1280-min-ERalpha GSE94023.ESR1.MCF-7_E2-1280-min-ERalpha 232 bp overlap

ChIP MCF-7_E2-160min-ERalpha GSE94023.ESR1.MCF-7_E2-160min-ERalpha 153 bp overlap

ChIP MCF-7_E2-20min-ERalpha GSE94023.ESR1.MCF-7_E2-20min-ERalpha 315 bp overlap

ChIP MCF-7_E2-320min-ERalpha GSE94023.ESR1.MCF-7_E2-320min-ERalpha 159 bp overlap

ChIP MCF-7_E2-40min-ERalpha GSE94023.ESR1.MCF-7_E2-40min-ERalpha 278 bp overlap

ChIP MCF-7_E2-5min-ERalpha GSE94023.ESR1.MCF-7_E2-5min-ERalpha 283 bp overlap

ChIP MCF-7_E2-80min-ERalpha GSE94023.ESR1.MCF-7_E2-80min-ERalpha 241 bp overlap

ChIP MCF-7_E2_45m GSE67295.ESR1.MCF-7_E2_45m 162 bp overlap

ChIP MCF-7_PROG GSE68355.ESR1.MCF-7_PROG 276 bp overlap

ChIP MCF-7_PaPE-1_OA GSE93510.ESR1.MCF-7_PaPE-1_OA 315 bp overlap

ChIP MCF-7_R5020 GSE68355.ESR1.MCF-7_R5020 250 bp overlap

ChIP MCF-7_SHCRT_E2 ERP000380.ESR1.MCF-7_SHCRT_E2 179 bp overlap

ChIP MCF-7_SICTR_E2 GSE40129.ESR1.MCF-7_SICTR_E2 121 bp overlap

ChIP MCF-7_Veh_OA GSE93510.ESR1.MCF-7_Veh_OA 215 bp overlap

ChIP MCF-7_estradiol-DHT_4h GSE99626.ESR1.MCF-7_estradiol-DHT_4h 317 bp overlap

ChIP MCF-7_estradiol_4h GSE99626.ESR1.MCF-7_estradiol_4h 209 bp overlap

ChIP MCF-7_parental_4-hydroxytamoxifen GSE123284.ESR1.MCF-7_parental_4-hydroxytamoxifen 169 bp overlap

ChIP MCF-7_shFbxo GSE119702.ESR1.MCF-7_shFbxo 138 bp overlap

ChIP MCF-7_shFbxo_E2 GSE119702.ESR1.MCF-7_shFbxo_E2 138 bp overlap

ChIP MCF-7_vehicle GSE102410.ESR1.MCF-7_vehicle 175 bp overlap

ChIP T-47D GSE148277.ESR1.T-47D 341 bp overlap

ChIP T-47D_Y537S GSE148277.ESR1.T-47D_Y537S 250 bp overlap

ChIP T-47D_Y537S_E2 GSE148277.ESR1.T-47D_Y537S_E2 339 bp overlap

ChIP U2OS_100nM-E2 GSE151039.ESR1.U2OS_100nM-E2 351 bp overlap

ChIP U2OS_10nM-E2 GSE151039.ESR1.U2OS_10nM-E2 373 bp overlap

ChIP U2OS_10nM-E2-B GSE151039.ESR1.U2OS_10nM-E2-B 379 bp overlap

ChIP U2OS_E2 GSE26110.ESR1.U2OS_E2 129 bp overlap

GATA1 1 dataset

ChIP K-562 GSE107726.GATA1.K-562 165 bp overlap

GATA2 2 datasets

ChIP K-562 ENCSR000DKA.GATA2.K-562 302 bp overlap

ChIP TF1 GSE73207.GATA2.TF1 199 bp overlap

GATA4 5 datasets

ChIP DE DE-GATA4-1 497 bp overlap

ChIP DE DE-GATA4-2 1032 bp overlap

ChIP foregut GSE117136.GATA4.foregut 246 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 252 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 247 bp overlap

GATA6 11 datasets

ChIP AGS GSE51936.GATA6.AGS 151 bp overlap

ChIP DE DE-GATA6-1 451 bp overlap

ChIP DE DE-GATA6-2 695 bp overlap

ChIP DE DE-GATA6-2 257 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 481 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 498 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 455 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 1032 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 552 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 613 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 464 bp overlap

HAND2 1 dataset

ChIP CLB-Ga GSE90683.HAND2.CLB-Ga 313 bp overlap

HDAC1 1 dataset

ChIP K-562 ENCSR387UWP.HDAC1.K-562 363 bp overlap

HMBOX1 2 datasets

ChIP K-562 ENCSR757IIU.HMBOX1.K-562 165 bp overlap

ChIP K562 ENCFF317JJX 366 bp overlap

ChIP K-562 ENCSR005NMT.ID3.K-562 558 bp overlap

IFNA1 1 dataset

ChIP Huh-7_GFP GSE110511.IFNA1.Huh-7_GFP 146 bp overlap

ChIP DE_D1 S08-DE-d1-JUN-exp1 339 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 371 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 821 bp overlap

ChIP DE_D2 S54-DE-d2-JUN-exp2 320 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 383 bp overlap

ChIP islet ERP004003.MAFB.islet 244 bp overlap

MED1 3 datasets

ChIP HUVEC-C_siCTL GSE124892.MED1.HUVEC-C_siCTL 208 bp overlap

ChIP HUVEC-C_siERG GSE124892.MED1.HUVEC-C_siERG 339 bp overlap

ChIP HUVEC-C_siERG GSE124892.MED1.HUVEC-C_siERG 72 bp overlap

MLLT1 2 datasets

ChIP GM12878 ENCFF995GXC 576 bp overlap

ChIP GM12878 ENCSR552XSN.MLLT1.GM12878 502 bp overlap

ChIP K-562 ENCSR180NCY.MTA3.K-562 374 bp overlap

NANOG 1 dataset

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 237 bp overlap

NCAPH2 1 dataset

ChIP IMR-90_FLAG_OIS GSE118494.NCAPH2.IMR-90_FLAG_OIS 396 bp overlap

ChIP K-562 ENCSR000FCC.NFE2.K-562 51 bp overlap

NKX3-1 1 dataset

ChIP islet ERP004003.NKX3-1.islet 249 bp overlap

NR2F1 1 dataset

ChIP K-562 ENCSR970NKQ.NR2F1.K-562 336 bp overlap

NRIP1 1 dataset

ChIP MCF-7_E2 ERP005838.NRIP1.MCF-7_E2 151 bp overlap

PBX3 3 datasets

ChIP GM12878 ENCFF285BQQ 217 bp overlap

ChIP GM12878 ENCSR000BGR.PBX3.GM12878 105 bp overlap

ChIP GM12878 ENCSR000BGR.PBX3.GM12878 159 bp overlap

ChIP MCF-7_PROG GSE68355.PGR.MCF-7_PROG 200 bp overlap

POLR2A 1 dataset

ChIP A549 ENCFF748RAW 311 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 483 bp overlap

PRDM14 1 dataset

ChIP NCCIT GSE71675.PRDM14.NCCIT 104 bp overlap

PRDM6 1 dataset

ChIP HEK293 GSE76494.PRDM6.HEK293 142 bp overlap

RAD21 2 datasets

ChIP GP5D GSE51234.RAD21.GP5D 300 bp overlap

ChIP HCT-116 GSE131606.RAD21.HCT-116 289 bp overlap

REST 10 datasets

ChIP GM12878 ENCSR000BGF.REST.GM12878 90 bp overlap

ChIP GM12878 ENCSR000BQS.REST.GM12878 131 bp overlap

ChIP H1 ENCFF429RUE 245 bp overlap

ChIP HEK293 ENCFF073DOT 431 bp overlap

ChIP HEK293 ENCSR896UBV.REST.HEK293 249 bp overlap

ChIP K-562 ENCSR137ZMQ.REST.K-562 274 bp overlap

ChIP K-562 ENCSR000BMW.REST.K-562 151 bp overlap

ChIP PANC-1 ENCSR000BPK.REST.PANC-1 146 bp overlap

ChIP PFSK1 ENCSR000BOX.REST.PFSK1 171 bp overlap

ChIP WA01 ENCSR000BHM.REST.WA01 162 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 541 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 788 bp overlap

SMC1 2 datasets

ChIP DKO GSE131606.SMC1.DKO 121 bp overlap

ChIP HCAEC GSE101921.SMC1.HCAEC 203 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 696 bp overlap

STAT1_pS727 1 dataset

ChIP SET-2 GSE100566.STAT1_pS727.SET-2 259 bp overlap

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 188 bp overlap

ChIP GM12878 ENCSR000BQT.TCF3.GM12878 232 bp overlap

TEAD1 1 dataset

ChIP WTC11 ENCFF502QUV 355 bp overlap

THAP1 1 dataset

ChIP K-562 ENCSR000BNN.THAP1.K-562 107 bp overlap

ChIP HCT-116_IR GSE60267.TP53.HCT-116_IR 299 bp overlap

TRIM25 1 dataset

ChIP MDA-MB-231 GSE79588.TRIM25.MDA-MB-231 171 bp overlap

ChIP HEK293 ENCSR966PJJ.WT1.HEK293 312 bp overlap

ChIP Huh-7 GSE97411.YY1.Huh-7 439 bp overlap

ChIP WA01 GSE39096.YY1.WA01 150 bp overlap

ZBTB48 1 dataset

ChIP HEK293 ENCSR781EQJ.ZBTB48.HEK293 207 bp overlap

ZBTB7A 1 dataset

ChIP VCaP_FBS GSE123089.ZBTB7A.VCaP_FBS 225 bp overlap

ChIP GM12878 ENCSR000BND.ZEB1.GM12878 125 bp overlap

ChIP K-562 ENCSR004GKA.ZEB2.K-562 441 bp overlap

ChIP HEK293 ENCFF033NQQ 589 bp overlap

ZNF143 1 dataset

ChIP FLP143HA_T0 GSE39263.ZNF143.FLP143HA_T0 149 bp overlap

ZNF19 1 dataset

ChIP HEK293T GSE78099.ZNF19.HEK293T 391 bp overlap

ZNF24 1 dataset

ChIP K-562 ENCSR099NCH.ZNF24.K-562 245 bp overlap

ZNF398 1 dataset

ChIP H9 GSE133630.ZNF398.H9 154 bp overlap

ZNF467 1 dataset

ChIP HEK293 GSE76494.ZNF467.HEK293 203 bp overlap

ZNF664 2 datasets

ChIP HEK293 ENCFF343XSW 81 bp overlap

ChIP HEK293 ENCSR714LZQ.ZNF664.HEK293 169 bp overlap